Human newborn B cells mount an IFNAR-dependent humoral response to RSV

Publication date: Available online 5 December 2016
Source:Journal of Allergy and Clinical Immunology
Author(s): Jop Jans, Matthew Pettengill, Dhohyung Kim, Cas van der Made, Ronald de Groot, Stefanie Henriet, Marien I. de Jonge, Gerben Ferwerda, Ofer Levy

Teaser

This study provides evidence of a first line of human humoral defense against RSV infection in early life including the presence of natural neutralizing anti-RSV IgM as well as an IFN-β-mediated newborn B cell activation.


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