Ameloblastic fibrodentinoma and ameloblastic fibro-odontoma: an updated systematic review of cases reported in the literature

Publication date: Available online 6 January 2017
Source:Journal of Oral and Maxillofacial Surgery
Author(s): Bruno Ramos Chrcanovic, Ricardo Santiago Gomez
PurposeTo integrate the available data published on ameloblastic fibrodentinoma (AFD) and ameloblastic fibro-odontoma (AFO) into a comprehensive analysis of its clinical/radiologic features.MethodsAn electronic search was undertaken in August/2016. Eligibility criteria included publications reporting cases of AFD and/or AFO having enough clinical, radiological and histological information to confirm the diagnosis. Demographic data, lesion site and size, treatment approach, and recurrence were analyzed and compared between AFD and AFO.Results55 publications reporting 64 AFDs (60 central, 4 peripheral) and 137 publications reporting 215 AFOs (211 central, 3 peripheral, 1 unknown) were included. The difference in recurrence rate (when the information about recurrence was provided) was not statistically significant. The mean age of the patients affected by AFD was not statistically significantly different from those affected by AFO.ConclusionsAFD and AFO presented several similarities: higher prevalence in males and in mandibles, similar patients' mean age, rate of cortical bone perforation and of the lesions' association with displaced/unerupted teeth and tooth root resorption, mean lesion size, and recurrence rate. The lesions differed with regard to the presence of radiopacities and locularity. Taken together, our data do not support the concept of progressive maturation of these tumoral conditions.



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