Insulin effect on hearing recovery in idiopathic sudden sensorineural hearing loss: retrospective study of 145 patients

Abstract

1.We compared the hearing results of idiopathic sudden sensorineural hearing loss (ISSNHL) in normoglycemic patients versus those with pre-diabetes and diabetes mellitus (DM), including demographics and the impact of insulin administration.

2.The success rate for return of hearing in patients with DM was very high (80.0%) contrary to very low success rate for patients with pre-diabetes (38.2%).

3.High SD and MAGE in DM group could be explained by the effect of insulin and steroid treatment.

4.We believe the best explanation for the salutary impact of administration of insulin on hearing return was through reversal of ischemia

5.Intensive glucose management with insulin during steroid treatment in patients with ISSNHL and hyperglycemia beneficial to hearing recovery.

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