Predictive Value of Intraoperative Troponin I Elevation in Pediatric Living Donor Liver Transplant Recipients With Biliary Atresia.

Background: Pediatric living donor liver transplantation is associated with slight alteration in cardiac enzymes without ongoing acute cardiac injury, but available information about the significance of these changes is limited. The aims of this study were to analyze the link between the anomalies of intraoperative serum cardiac troponin I (cTnI) and acute lung injury during the first week after liver transplantation. Methods: In this retrospective study, 123 children suffered from biliary atresia were enrolled. Several perioperative variables, particularly cTnI before operation and at 30min of neohepatic phase were recorded. 64 recipients were divided into high-cTnI group (>=0.07ng/mL) and 59 recipients composed normal-cTnI group (=0.07ng/mL (OR=3.475, confidence interval 1.114-10.842) was the risk factors for acute lung injury after transplantation. The value of cTnI showed the close correlation with preoperative bilirubin (OR=1.005, confidence interval 1.002-1.008) and pretransplant albumin (OR=0.915, confidence interval 0.849-0.986). Conclusions: Intraoperative cTnI elevation was the significant prognostic risk factor in acute lung injury after pediatric living-donor liver transplantation for children with biliary atresia. And the value of cTnI was associated with preoperative bilirubin and albumin level. Copyright (C) 2017 Wolters Kluwer Health, Inc. All rights reserved.

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