Comparison of Ozone and Photobiomodulation Therapies on Mental Nerve Injury in Rats

Publication date: Available online 26 April 2017
Source:Journal of Oral and Maxillofacial Surgery
Author(s): Türker Yücesoy, Nükhet Kütük, Dilek Günay Canpolat, Alper ALKAN
AimThis study compares photobiomodulation (PBM) and ozone therapy (OT) techniques on mental nerve injury by counting Schwann cell (SC) numbers, fasciculated nerve branches numbers and measuring the fascicule areas of the nerves.MethodsIn the present study, the effects of ozone and PBM therapies on mental nerve injury were evaluated. Mental nerves of 27 rats were partly suturated and allocated into three groups. Group 1 recevied no treatment, whereas OT and PBM therapies were administered in Group 2 and Group 3, respectively. Number of fascicules after nerve branching and Schwann cell counting before and after nerve injury have been evaluated histologically.ResultsA better healing pattern was observed in the treatment groups. The number of Schwann cells were significantly greater in OT and PBM groups then control groups.ConclusionsOral and maxillofacial surgeons must be familiar with the differential diagnosis, prevention, and management of neurosensory disturbances. This study provides insights into the management of neurosensory disturbances related to mental nerve injury by using OT and PBM. Our study clearly suggest that OT and PBM are promising novel methods in the treatment of mental nerve injury.



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