How Microneedles Can Change Cutaneous Drug Delivery

The year was 1971, and Intel had unveiled its first microchip. That same year, the US patent office registered an application from Martin S. Gerstel and Virgil A. Place for the drug delivery device that we know today as a microneedle array. Amazingly, although the sketch submitted by the inventors described a device very much like what we recognize today as a microneedle array, the technology to produce such small needles did not exist at that time. The vision became a reality when microfabrication technology made manufacturing of microscopic needles possible.

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