Array-based sequencing of filaggrin gene for comprehensive detection of disease-associated variants

Publication date: Available online 19 October 2017
Source:Journal of Allergy and Clinical Immunology
Author(s): X. F. Colin C. Wong, Simon L.I.J. Denil, Jia Nee Foo, Huijia Chen, Angeline Su Ling Tay, Rebecca L. Haines, Mark B.Y. Tang, W. H. Irwin McLean, Aileen Sandilands, Frances J.D. Smith, E. Birgitte Lane, Jianjun Liu, John E.A. Common

Teaser

Comprehensive sequencing of FLG is a challenging endeavour. We have developed a method using array-based amplicon PCR and NGS for a robust and cost efficient method to analyze this major atopic dermatitis risk factor.


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