Αρχειοθήκη ιστολογίου

Αλέξανδρος Γ. Σφακιανάκης
ΩτοΡινοΛαρυγγολόγος
Αναπαύσεως 5
Άγιος Νικόλαος Κρήτη 72100
2841026182
6032607174

Τρίτη 6 Φεβρουαρίου 2018

Characterization of drug-neutralizing antibodies in patients with Fabry disease during infusion

Publication date: Available online 5 February 2018
Source:Journal of Allergy and Clinical Immunology
Author(s): Malte Lenders, Boris Schmitz, Stefan Martin Brand, Dirk Foell, Eva Brand
In patients with Fabry disease, neutralizing anti-drug antibodies were identified as IgG4 isotypes. The determination of antibody titers during infusions indicated that high dosages of enzyme overcome anti-drug antibody titers, necessitating individually tailored dose adjustment.



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