Rhabdomyolysis after Prolonged Surgery: Report of Two Cases and Review of Literature

Publication date: Available online 2 February 2018
Source:Journal of Oral and Maxillofacial Surgery
Author(s): Rebecca Grammer, Jingping Wang, Edward Lahey
Rhabdomyolysis is a condition in which damaged muscle tissue breaks down and intracellular contents, including myoglobin, are released into circulation. This produces a non-specific clinical syndrome including electrolyte disturbances, hypovolemia, metabolic acidosis, coagulopathies, and risk for acute kidney injury. Rhabdomyolysis has been reported as a complication of prolonged surgical procedures but has rarely been reported in the oral and maxillofacial surgery literature. Early diagnosis and treatment of rhabdomyolysis are important to avoid long-term complications such as renal failure. We present two cases of postoperative rhabdomyolysis following prolonged maxillofacial surgical procedures in which the patients were managed without long-term sequelae. The pathophysiology, risk factors, diagnosis and treatment for postoperative rhabdomyolysis are discussed here with a brief review of the literature.



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