Intestinal microbial-derived sphingolipids are inversely associated with childhood food allergy

Publication date: Available online 2 May 2018
Source:Journal of Allergy and Clinical Immunology
Author(s): Kathleen Lee-Sarwar, Rachel S. Kelly, Jessica Lasky-Su, D. Branch Moody, Alex R. Mola, Tan-Yun Cheng, Laurie E. Comstock, Robert S. Zeiger, George T. O'Connor, Megan T. Sandel, Leonard B. Bacharier, Avraham Beigelman, Nancy Laranjo, Diane R. Gold, Supinda Bunyavanich, Jessica H. Savage, Scott T. Weiss, Patrick J. Brennan, Augusto A. Litonjua

Teaser

Intestinal Bacteroides-derived sphingolipids in infancy were inversely associated with food allergy among sensitized subjects. This may be mediated in part by invariant NK T cell activation.


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