Screening for Wiskott-Aldrich syndrome by flow cytometry

Publication date: Available online 3 May 2018
Source:Journal of Allergy and Clinical Immunology
Author(s): Samuel Chiang

Teaser

Quantifying WAS protein predicts WAS mutations with 89% sensitivity and 100% specificity, but correlated poorly with disease severity. Absent WAS protein confirms WAS mutation but the presence of WAS protein must be corroborated by sequencing.


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