Odontogenic tumours and lesions from 1992-2016 in a single specialist Oral and Maxillofacial Pathology Unit in the United Kingdom

Publication date: Available online 5 October 2018

Source: Oral Surgery, Oral Medicine, Oral Pathology and Oral Radiology

Author(s): B.S.M.S. Siriwardena, Hannah Crane, Niall O'Neill, Rasha Abdelkarim, Daniel J. Brierley, Christopher D. Franklin, Paula M. Farthing, Paul M. Speight, Keith D. Hunter

Abstract

Objectives

Odontogenic tumours (ODTs) are a heterogeneous group of lesions derived from elements of the tooth-forming tissues. There are no published detailed data on the incidence of odontogenic tumours in the UK.

Aim

to retrospectively describe the range and incidence of odontogenic tumours from 1992-2016 in a single specialist unit and to compare this with other populations.

Study Design

Using the Oral and Maxillofacial Pathology database, Sheffield, both local and referred consultation cases were included. A proportion of diagnoses were re-classified in accordance with the 2017 WHO classification.

Results

In total, 559 odontogenic tumours were diagnosed. Overall, the most common lesions were ameloblastoma (196; 33.8%), odontome (148; 25.5%) and odontogenic myxoma (37; 6.3%), but this varied between local and referral case populations, with odontomes most common in the local population (43%). The sites affected, gender and age of patients were similar to other western populations. Malignant ODTs comprised 33 cases (5.7%), of which nine (27.3%) were ameloblastic carcinoma. The majority of the malignant ODTs were referral cases.

Conclusions

These are the first detailed data on odontogenic tumours within a UK population and the pattern of incidence from the local population is similar to other western populations. The exceptional rarity of malignant ODTs emphasises the need for specialist centres in order to gain diagnostic experience.

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