Low dose provocation and skin tests in patients with hypersensitivity to Gadolinium‐based contrast agents

Abstract

Reported reactions rates with gadolinium‐based contrast agents (GBCA) ranged from 0.07 to 2.4%, the rate of hypersensitivity reaction (HS) is around 0.1% (1) and immediate and delayed HS have been reported (1–4). The diagnosis of HS to GBCA is challenging, based on clinical history and skin tests. Although little data is available on the performances of the GBCA skin tests, its negative predictive value appears to be of interest (5).

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