Multiple cutaneous reticulohistiocytomas after haematopoietic cell transplantation: contribution of donor and host‐derived cells

Abstract

Reticulohistiocytoma or reticulohistiocytosis of the skin is a histiocytic disorder which is histologically characterized by the presence of numerous reticulohistiocytes: large histiocytes with an abundant eosinophilic cytoplasm. The aetiology of reticulohistiocytosis and the origin of reticulohistiocytes are unknown. Multiple cutaneous reticulohistiocytomas (MCR) is a reticulohistiocytosis of the skin that is characterized by generalized eruptions and an absence of articular symptoms or internal malignancies. Around 20 MCR cases have been reported in the literature, but the association between reticulohistiocytosis and haematopoietic cell transplantation (HCT) has not been described.

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