Anti interleukin 12/23 in the treatment of erythema nodosum and Crohn disease: A case report

Abstract

Erythema nodosum is one of the most common dermatologic conditions associated with Inflammatory Bowel Disease (IBD) such as Crohn disease and it is characterized by hypodermic connectival septs inflammation. Crohn disease is an IBD that may interest any part of the gastrointestinal tract from mouth to anus. Nowadays biological drugs as anti tumor necrosis factor alpha (adalimumab) and more recently, anti interleukin 12/23 (ustekinumab) antibodies are utilized in the treatment of IBD with good results. We present a case of a 43 y.o. woman affected by Crohn disease with extra intestinal manifestations (Erythema nodosum) treated with ustekinumab. The patient showed a complete remission of both the dermatological and gastroenterological symptoms.

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