Risk factors for acne development in the first 2 years after initiating masculinizing testosterone therapy among transgender men

To the Editor: Female-to-male transgender patients (herein referred to as transgender men) receive masculinizing doses of testosterone to induce virilization and suppress menstruation. Studies have shown that elevated androgen levels among transgender men have been associated with an increased incidence of acne.1-5 Studies suggest that testosterone therapy increases the development of acne, though severe acne occurs only rarely.3 Our study assessed the timing of acne onset relative to initiation of testosterone therapy in transgender men and the biologic, behavioral, and sociodemographic predictors of acne in this population.

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