Prospective Follow-up of Outcomes in Patients Receiving Photodynamic Therapy for Neoplastic Diseases
Prospective Follow-up of Outcomes in Patients Receiving Photodynamic Therapy for Neoplastic Diseases: *Condition*: Neoplastic Disease *Intervention*: Other: Data Collection *Sponsor*: Abramson Cancer Center of the University of Pennsylvania From 1996-present, we have used photodynamic therapy (PDT) to treat a number of neoplastic diseases both on prospective research protocols (for head and neck cancer, pleural malignancies, peritoneal carcinomatosis or sarcomatosis and prostate cancer) as well as for FDA approved and off label or compassionate exemption indications (neoplas... περισσότερα »
Thoracic Spine Manipulation With or Without Trigger Point Dry Needling for Mechanical Neck Pain
Short-Term Response of Thoracic Spine Manipulation With or Without Trigger Point Dry Needling for Mechanical Neck Pain: *Condition*: Neck Pain *Interventions*: Procedure: Thoracic spinal manipulation; Procedure: Trigger point dry needling; Behavioral: Cervical range of motion exercises; Behavioral: Posterior neck muscle activation exercise; Procedure: Trigger point dry needling sham; Device: Seirin J-type stainless steel needles, 0-2-0.3 x 40-50 mm *Sponsor*: Brooke Army Medical Center ArmsAssigned InterventionsExperimental: SMT and TDN Thoracic spinal manipulatio... περισσότερα »
IJERPH, Vol. 13, Pages 129: Behavior Change without Behavior Change Communication: Nudging Handwashing among Primary School Students in Bangladesh
Behavior change communication for improving handwashing with soap can be labor and resource intensive, yet quality results are difficult to achieve. Nudges are environmental cues engaging unconscious decision-making processes to prompt behavior change. In this proof-of-concept study, we developed an inexpensive set of nudges to encourage handwashing with soap after toilet use in two primary schools in rural Bangladesh. We completed direct observation of behaviors at baseline, after providing traditional handwashing infrastructure, and at multiple time periods following targeted ha... περισσότερα »
Remote Sensing, Vol. 8, Pages 64: Correction: Pimont, F. et al. Estimating Leaf Bulk Density Distribution in a Tree Canopy Using Terrestrial LiDAR and a Straightforward Calibration Procedure. Remote Sens. 2015, 7(6), 7995-8018
After publication of the research paper [1] an error during the data analysis process was recognized. [...] from #Medicine via ola Kala on Inoreader http://ift.tt/1ROsWpR via IFTTT
Sustainability, Vol. 8, Pages 77: Determinants of Financial Sustainability for Farm Credit Applications—A Delphi Study
Farmers use credit from commercial credit providers to finance production activities. Commercial credit providers have to predict the financial sustainability of the enterprise to ensure that the borrower will have the ability to repay the loan. A Delphi study was conducted to explore what factors are used as indicators of loan-repayment ability of farmers. The objective was not only to identify factors that are currently considered, but also to identify other personal attributes that may improve the accuracy in predicting the repayment ability of potential borrowers. The Delphi w... περισσότερα »
Energies, Vol. 9, Pages 44: Screening Criteria and Considerations of Offshore Enhanced Oil Recovery
The application of enhanced oil recovery (EOR) in offshore oil fields has received significant attention due to the potentially enormous amount of recoverable oil. However, EOR application offshore is in its very early stage due to conditions that are more complex than onshore oil fields, owing to the unique parameters present offshore. Therefore, successful EOR applications in offshore oil fields require different screening criteria than those for conventional onshore applications. A comprehensive database for onshore applications of EOR processes together with a limited offshore ... περισσότερα »
Remote Sensing, Vol. 8, Pages 62: Quantifying Multi-Decadal Change of Planted Forest Cover Using Airborne LiDAR and Landsat Imagery
Continuous monitoring of forest cover condition is key to understanding the carbon dynamics of forest ecosystems. This paper addresses how to integrate single-year airborne LiDAR and time-series Landsat imagery to derive forest cover change information. LiDAR data were used to extract forest cover at the sub-pixel level of Landsat for a single year, and the Landtrendr algorithm was applied to Landsat spectral data to explore the temporal information of forest cover change. Four different approaches were employed to model the relationship between forest cover and Landsat spectral da... περισσότερα »
IJERPH, Vol. 13, Pages 128: Occupants’ Perceptions of Amenity and Efficiency for Verification of Spatial Design Adequacy
The best spatial design condition to satisfy the occupancy needs of amenity and efficiency is determined through analyzing the spatial design adequacy (SDA). In this study, the relationship between the space design elements and space on future occupants' perception are analyzed. The thirty-three participants reported their self-evaluated SDA that describes the quality of eight alternative housing living rooms with different spatial factors. The occupants were guided through the perception processing elaboration in order for them to evaluate the actual perception in the real space. ... περισσότερα »
Crystals, Vol. 6, Pages 11: Accelerated Approach for the Band Structures Calculation of Phononic Crystals by Finite Element Method
We present here a fast and easily realized computational approach based on the finite element methods with consistent and lumped mass matrices (CM-FEM and LM-FEM, respectively), and the Bloch's theorem, to calculate the elastic band structures of phononic crystals. Two improvements, the adjustment of the introduction of Bloch's theorem as well as weighting treatment of consistent and lumped mass matrices, are performed. Numerical simulations show that convergence speed is accelerated obviously. Furthermore, the method is verified by analytical solutions in specified homogeneous ca...περισσότερα »
Energies, Vol. 9, Pages 45: Matching of Energy Provisions in Multihop Wireless Infra-Structures
Recently there have been large advances in energy technologies for battery-operated systems, including green energy resources and high capacity batteries. The effective use of battery energy resources in wireless infrastructure networks to improve the versatility and reliability of wireless communications is an important issue. Emerging applications of smart cities, Internet of Things (IoT), and emergency responses highly rely on the basic communication network infrastructures that enable ubiquitous network connections. However, energy consumption by nodes in a wireless infrastruc... περισσότερα »
Small mandibular asymmetries may be corrected by unilateral sagittal split ramus osteotomy (USSO)
Unilateral sagittal split mandibular ramus osteotomy: indications and geometry: Small mandibular asymmetries may be corrected by unilateral sagittal split ramus osteotomy (USSO). This study had two objectives: first to define the geometric changes in the mandibular condyle and the lower incisor teeth that result from the rotation of the major segment (n=26), and secondly to examine in a clinical study the temporomandibular joints (TMJ) of 23 patients after correction of mandibular asymmetry by USSO to find out if there were any long-term adverse effects. Small mandibular asymmetries... περισσότερα »
Radical surgery for neoplasms of the tongue can endanger one or both lingual arteries, threatening the survival of the remaining tissue and the recovery of speech and swallowing
Arterial Anastomosis in the Tongue via Oral and Maxillofacial Surgery Publication date: Available online 7 January 2016 *Source:*Journal of Oral and Maxillofacial Surgery Author(s): Jennifer O’Neill, John Shaw-Dunn, Stuart Robertson, Paul Rea PurposeRadical surgery for neoplasms of the tongue can endanger one or both lingual arteries, threatening the survival of the remaining tissue and the recovery of speech and swallowing.Our hypothesis is that although there is little anastomosis in the substance of the tongue, arterial anastomoses outside of it could provide a collateral circulation... περισσότερα »
Among patients undergoing ablative treatment for oral cancer, does the provision of oral rehabilitation improve the quality of life?
A review of the current literature via Oral and Maxillofacial Surgery Publication date: Available online 7 January 2016 *Source:*Journal of Oral and Maxillofacial Surgery Author(s): Vahe Petrosyan, Dimity Ball, Rebecca Harrison, Phillip Ameerally Background & PurposeThe impact of oral cancer and its treatment is well documented; therefore, oral rehabilitation (OH), e.g. with prosthetics, osseointegrated implants, etc., can be indicated to restore some level of form, function and well-being. The purpose of this study was to review the current literature and evaluate the impact of OH on ...περισσότερα »
Chronic refractory myofascial pain and denervation supersensitivity as global public health disease
Chronic pain with a 30.3% global prevalence significantly impacts universal health. Low back pain has a 9.4% prevalence worldwide causing the most widespread disability. Neck pain ranks 4th highest regarding years lived with disability with a 4.9% prevalence worldwide. The principal cause of pain in 85% of patients visiting a tertiary pain clinic has a myofascial origin. The root cause is multifocal neuromuscular ischaemia at myofascial trigger points from muscle tightening and shortening following spondylotic radiculopathy induced partial denervation. Chronic refractory myofascial... περισσότερα »
Case 1-2016: An 18-Year-Old Man with Fever, Abdominal Pain, and Thrombocytopenia
Presentation of Case. Dr. Emily R. Lynch (Pediatrics): An 18-year-old man was admitted to this hospital because of fever and pain in the lower abdomen, groin, and scrotum. The patient had been well until 4 days before admission, when fatigue, subjective fever, and chills developed. The next day, he… from Cases via ola Kala on Inoreader http://ift.tt/1ROiDlH via IFTTT
Pharyngeal Flap is Effective Treatment for Post Maxillary Advancement Velopharyngeal Insufficiency
in Patients with Repaired Cleft Lip and Palate via Oral and Maxillofacial Surgery Publication date: Available online 7 January 2016 *Source:*Journal of Oral and Maxillofacial Surgery Author(s): Kelley M. Dentino, Eileen M. Marrinan, Katherine Brustowicz, John B. Mulliken, Bonnie L. Padwa PurposePatients with repaired cleft lip and/or palate (CL/P) can develop velopharyngeal insufficiency after Le Fort I maxillary advancement. The aim of this study was to evaluate speech outcomes in patients who required a pharyngeal flap after Le Fort I maxillary advancement.Patients and MethodsRetros... περισσότερα »
A modified preauricular approach for treating intracapsular condylar fractures to prevent facial nerve injury: the supratemporalis approach
A modified preauricular approach for treating intracapsular condylar fractures to prevent facial nerve injury: the supratemporalis approach via Oral and Maxillofacial Surgery Publication date: Available online 7 January 2016 *Source:*Journal of Oral and Maxillofacial Surgery Author(s): Hui Li, Gang Zhang, Junhui Cui, Weilong Liu, Dilnu Dilxat, Lei Liu PurposeThe facial nerve remains at risk of injury with the preauricular approach and thus preservation of the functional integrity of the facial nerve is considered a significant factor in the success of temporomandibular joint surgery. T...περισσότερα »
Epstein Barr Virus–Positive Diffuse Large B-Cell Non-Hodgkin’s Lymphoma with widespread skeletal muscle, masticatory muscle, and parotid gland involvement, as well as the development of interesting erythematous lesions in the neck during chemotherapy
Unusual Presentation of Epstein Barr Virus–Positive Diffuse Large B-Cell Non-Hodgkin’s Lymphoma of the Elderly via Oral and Maxillofacial Surgery Publication date: Available online 7 January 2016 *Source:*Journal of Oral and Maxillofacial Surgery Author(s): Bosun Hong, Vahe Petrosyan, Anton R. Kruger We describe a case of a 76-year-old woman diagnosed with Epstein Barr virus (EBV)-positive diffuse large B-cell non-Hodgkin’s lymphoma of the elderly. She had an unusual presentation of the disease with widespread skeletal muscle, masticatory muscle, and parotid gland involvement, as well a... περισσότερα »
The “Papillon” Anterolateral Thigh Flap for Total Pharyngolaryngectomy Reconstruction
The Value of the “Papillon” Anterolateral Thigh Flap for Total Pharyngolaryngectomy Reconstruction: A Retrospective Case Series via Oral and Maxillofacial Surgery Publication date: February 2016 *Source:*Journal of Oral and Maxillofacial Surgery, Volume 74, Issue 2 Author(s): Naseem Ghazali, Todd C. Hanna, Donita Dyalram, Joshua E. Lubek PurposeThe tubed, buried anterolateral thigh (ALT) flap is a popular reconstruction method for total pharyngolaryngectomy defects. The “papillon”-designed ALT flap, described by Hayden et al, offers an alternative method of using the ALT flap in this si...περισσότερα »
Natural Head Postures of Patients With Facial Asymmetry in Frontal View
Are Corrected After Orthognathic Surgeries via Oral and Maxillofacial Surgery Publication date: February 2016 *Source:*Journal of Oral and Maxillofacial Surgery, Volume 74, Issue 2 Author(s): Ji-Youn Kim, Moon-Ho Kang, Jun-Young You, Hyeon-Gun Jee, Jin Wook Yi, Byoung-Ho Kim PurposeAlthough orthognathic surgeries focus on adjustment of facial asymmetry (FA), many clinicians know by experience that the natural head posture (NHP) also is corrected after the surgery. The authors examined whether this was indeed the case by the measuring the NHP during the course of orthognathic treatment... περισσότερα »
Geriatric Facial Trauma
Interpersonal Violence is Associated with Increased Severity of Geriatric Facial Trauma via Oral and Maxillofacial Surgery Publication date: Available online 7 January 2016 *Source:*Journal of Oral and Maxillofacial Surgery Author(s): Joseph E. Cillo, Talmage M. Holmes BackgroundThe geriatric population is rapidly increasing in number with increased demand on health care resources including those spent on the treatment of maxillofacial trauma. The purpose of this analysis was to investigate the independent and cumulative associations between potential risk factors (age, gender, mechani...περισσότερα »
Effect of Aging on Periodontal Inflammation, Microbial Colonization, and Disease Susceptibility
Periodontitis is a chronic inflammatory disease induced by a biofilm that forms on the tooth surface. Increased periodontal disease is associated with aging. We investigated the effect of aging on challenge by oral pathogens, examining the host response, colonization, and osteoclast numbers in aged versus young mice. We also compared the results with mice with lineage-specific deletion of the transcription factor FOXO1, which reduces dendritic cell (DC) function. Periodontitis was induced by oral inoculation of *Porphyromonas gingivalis* and *Fusobacterium nucleatum* in young (4 t... περισσότερα »
Selective versus comprehensive neck dissection in T1/2 oral squamous cell carcinoma patients with cN0pN+ neck
Selective versus comprehensive neck dissection in T1/2 oral squamous cell carcinoma patients with cN0pN+ neck via Oral and Maxillofacial Surgery Publication date: Available online 7 January 2016 *Source:*Journal of Oral and Maxillofacial Surgery Author(s): Li-zhong Liang, Xiang-qi Liu, Qian-ying Kong, Gui-qing Liao PurposeThere is still no consensus on the oncologic safety of selective neck dissection (SND) in the management of pathologically positive neck in oral cavity squamous cell carcinoma patients. This study aimed to compare the clinical outcome between the selective and comprehe... περισσότερα »
Sialendoscopy of salivary glands affected by Sjögren’s syndrome
. A randomized controlled pilot study via Oral and Maxillofacial Surgery Publication date: Available online 7 January 2016 *Source:*Journal of Oral and Maxillofacial Surgery Author(s): Derk Jan Jager, K. Hakki Karagozoglu, Floor Maarse, Henk S. Brand, Tim Forouzanfar PurposeSialendoscopy of the major salivary glands could possibly alleviate the oral symptoms of Sjogren’s syndrome and restore salivary function. The aim of this pilot study was therefore to evaluate the effect of sialendoscopy of the major salivary glands on salivary flow, saliva composition and mouthfeel in Sjögren’s syn...περισσότερα »
Submandibular Fistula After Reconstruction for Osteoradionecrosis
Role of Negative-Pressure Wound Therapy in the Management of via Oral and Maxillofacial Surgery Publication date: February 2016 *Source:*Journal of Oral and Maxillofacial Surgery, Volume 74, Issue 2 Author(s): Da-ming Zhang, Zhao-hui Yang, Pei-lin Zhuang, You-yuan Wang, Wei-liang Chen, Bin Zhang PurposeAlthough negative-pressure wound therapy (NPWT) for complicated wounds has been extensively studied, it is rarely used in cases involving a submandibular fistula due to radiation-induced osteoradionecrosis of the mandible. This study aimed to investigate the efficacy of NPWT for submand... περισσότερα »
Correlation between preoperative predictions and surgical findings in the parotid surgery for tumors
Correlation between preoperative predictions and surgical findings in the parotid surgery for tumors: Background: To compare preoperative CT/MRI based predictions with real surgical findings for deep lobe parotid gland surgery. Methods: The study analyzed 122 parotidectomies (2004–2014) for benign tumor removal. The facial nerve, the Utrecht line, the Conn’s arc, and the retromandibular vein were used as landmarks for CT/MRI presurgical evaluation of patients. We assessed 106 CT images and 86 MRI images. The study compared preoperative evaluation of tumor location with its actual loc...περισσότερα »
TGFβ1-Smad3-Jagged1-Notch1–Slug signaling pathway takes part in tumorigenesis and progress of tongue squamous cell carcinoma
TGFβ1-Smad3-Jagged1-Notch1–Slug signaling pathway takes part in tumorigenesis and progress of tongue squamous cell carcinoma: Background TGFβ1 and Smad3 play an important role in the process of EMT. TGFβ1 regulates the expression of Jagged1 by modulating Notch signaling. Jagged1 is related to tumor invasion, metastasis, chemotherapy resistance, and tumor immune escape. The aims of this study are to examine deregulation of TGFβ1-Smad3-Jagged1-Notch1-Slug signaling in TSCC and to investigate its roles in TSCC progression. Materials and Methods Notch1, Smad3, Jagged1 and Slug proteins ... περισσότερα »
Prevalence and subjective knowledge of tongue lesions
in an Indian population via ScienceDirect Publication: Journal of Oral Biology and Craniofacial Research Publication date: Available online 13 January 2016 *Source:*Journal of Oral Biology and Craniofacial Research Author(s): Preeti Tomar Bhattacharya, Rupam Sinha, Sumona Pal AimThe current study was designed to determine prevalence of various tongue lesions and their association with age, gender, systemic illness, deleterious habits, and distribution over the surfaces of tongue. It also explored the awareness and knowledge of subjects in relation to presence of tongue lesions, etiolo...περισσότερα »
Carotid cavernous sinus fistula associated with Le Fort III osteotomy
An anatomical study of the pathophysiology of carotid cavernous sinus fistula associated with Le Fort III osteotomy: Carotid-cavernous sinus fistula (CCF) is a rare complication occurring after the Le Fort osteotomy. We aimed to elucidate the cause of CCF in the Le Fort osteotomy. Summary Carotid-cavernous sinus fistula (CCF) is a rare complication occurring after the Le Fort osteotomy. We aimed to elucidate the cause of CCF in the Le Fort osteotomy. Methods Eleven fresh cadavers were used. After craniotomy, a Le Fort III bipartition osteotomy was then performed. On the left side,... περισσότερα »
Computer-assisted design and computer-aided manufacturing (CAD/CAM) technology in nasoalveolar molding (NAM)
Pitfalls and Solutions in Virtual Design of Nasoalveolar Molding Plates by Using CAD/CAM Technology – a Preliminary Clinical Study: Computer-assisted design and computer-aided manufacturing (CAD/CAM) technology in nasoalveolar molding (NAM) should save time and manpower and reduce family input in cases of cleft lip and palate.Intraoral casts from twelve infants with complete unilateral cleft lip and palate were taken immediately after birth (T1) and after (T2) NAM treatment, digitalized, and transformed into STL data. The infants were randomized into Group 1 (n = 6) receiving conven...περισσότερα »
Persistent Upgaze Restriction after Orbital Floor Fracture Repair
Persistent Upgaze Restriction after Orbital Floor Fracture Repair: Cranial Maxillofac Trauma Reconstruction DOI: 10.1055/s-0035-1570076 Here we present two cases of marked postoperative upgaze restriction after successful repair of orbital floor fracture and release of inferior rectus entrapment. In both cases, follow-up imaging showed enlargement of the inferior rectus, and gradual resolution of gaze limitation was observed over several months of conservative management. Thus, in patients with postoperative findings suggestive of residual inferior rectus entrapment, follow-up imag... περισσότερα »
Factors that affect the quality of life of patients with oral cancer who have had their defects reconstructed immediately after excision of the tumour
Factors that affect the quality of life of patients with oral cancer who have had their defects reconstructed immediately after excision of the tumour: Physical, social, and psychological factors profoundly affect the quality of life (QoL) of patients with oral cancer. Here we have investigated these factors in patients who have had resection and reconstruction of their oral cancer. We have assessed patients who had reconstructions with a pectoralis major myocutaneous (PMM) flap or a free anterolateral thigh (ALT) perforator flap using the University of Washington Quality of Life ve... περισσότερα »
MSG-Evoked c-Fos Activity in the Nucleus of the Solitary Tract Is Dependent upon Fluid Delivery and Stimulation Parameters
MSG-Evoked c-Fos Activity in the Nucleus of the Solitary Tract Is Dependent upon Fluid Delivery and Stimulation Parameters: The marker of neuronal activation, c-Fos, can be used to visualize spatial patterns of neural activity in response to taste stimulation. Because animals will not voluntarily consume aversive tastes, these stimuli are infused directly into the oral cavity via intraoral cannulae, whereas appetitive stimuli are given in drinking bottles. Differences in these 2 methods make comparison of taste-evoked brain activity between results that utilize these methods proble... περισσότερα »
Immediate results of photodynamic therapy for the treatment of halitosis
Immediate results of photodynamic therapy for the treatment of halitosis in adolescents: a randomized, controlled, clinical trial: AbstractLight with or without chemical agents has been used to induce therapeutic and antimicrobial effects. With photodynamic therapy, the antimicrobial effect is confined to areas covered by a photosensitive dye and irradiated with light. The aim of the present study was to evaluate the effect of photodynamic therapy for the treatment of halitosis in adolescents through the analysis of volatile sulfur compounds, especially sulfide. A controlled, clini... περισσότερα »
Treatment of hypertrophic scars and keloids by fractional carbon dioxide laser: a clinical, histological, and immunohistochemical study
Treatment of hypertrophic scars and keloids by fractional carbon dioxide laser: a clinical, histological, and immunohistochemical study: AbstractTreatment of keloids (K) and hypertrophic scars (HTS) is challenging. A few case reports reported good results in HTS treated by fractional CO2 laser. The aim of the present study was the assessment of the clinical response as well as histological changes in K and HTS treated by fractional CO2 laser and the role of matrix metalloproteinase 9 (MMP9) in the response. A randomized half of the scar was treated by fractional CO2 laser in 30 pat...περισσότερα »
455-nm blue LED to reduce the load of Staphylococcus aureus and Candida albicans biofilms in compact bone tissue
In vitro effectiveness of 455-nm blue LED to reduce the load of Staphylococcus aureus and Candida albicans biofilms in compact bone tissue: AbstractThe aim of this study was to evaluate the effectiveness of a 455-nm blue light-emitting diode (LED), at different application times, to reduce the load of *Staphylococcus aureus* and *Candida albicans* biofilms applied to compact bone tissue. The microorganisms *S. aureus* (ATCC 25923) and *C. albicans* (ATCC 18804) were used to form biofilms on 160 specimens of compact bones that had been divided into eight experimental groups (*n* = 1... περισσότερα »
A locally delivered gel containing green tea extract
Clinical effect of locally delivered gel containing green tea extract as an adjunct to non-surgical periodontal treatment: AbstractGreen tea catechins had an in vitro antibacterial effect against periodontopathic bacteria and were able to inhibit destruction of the periodontal tissue. In this study, we aimed to evaluate the effect of locally delivered gel containing green tea extract as an adjunct to non-surgical periodontal treatment. Forty-eight subjects who had teeth with probing pocket depth of 5–10 mm were randomly allocated into the test or control group. Probing pocket depth... περισσότερα »
Angioleiomyoma of the tongue
Angioleiomyoma of the tongue: a case report and review of the literature: AbstractAngioleiomyoma (AL) is a benign tumor derived from smooth muscle. The overwhelming majority of ALs occur in the uterus, gastrointestinal tract, or skin; AL of the oral cavity is infrequent, and AL of the tongue is particularly rare. The present report describes a case of AL of the tongue that resulted in a good outcome. We also review the literature with a special emphasis on the etiology of ALs. It is generally agreed that minor trauma, venous stasis, and hormonal changes are etiological factors for ... περισσότερα »
Prospective evaluation of radiation-induced skin toxicity in a race/ethnically diverse breast cancer population
fasoladaellinikiστοOTOLARYNGOLOGY LIFELONG LEARNING : OTOLARYNGOLOGY BY ALEXANDROS SFAKIANAKIS,GREECE CRETE,ANAPAFSEOS 5 AGIOS NIKOLAOS 72100,TEL : 00302841026182,00306932607174Πριν από 14 δευτερόλεπτα
Abstract We evaluated predictors of radiation-induced skin toxicity in a prospective study of a tri-racial/ethnic breast cancer population. We evaluated patient demographics, tumor characteristics, and treatment variables in the first 392 patients in a prospective study assessing radiation-induced skin toxicity. Logistic regression analyses were conducted to evaluate potential predictors of skin toxicity. The study consists […]
An Age Old Problem? Estimating the Impact of Dementia on Past Human Populations
fasoladaellinikiστοOTOLARYNGOLOGY LIFELONG LEARNING : OTOLARYNGOLOGY BY ALEXANDROS SFAKIANAKIS,GREECE CRETE,ANAPAFSEOS 5 AGIOS NIKOLAOS 72100,TEL : 00302841026182,00306932607174Πριν από 14 δευτερόλεπτα
Objective: To model the impact of dementia on past societies. Method: We consider multiple lines of evidence indicating elderly individuals to have been more common throughout the past than is frequently accepted. We then apply known dementia incidence/prevalence rates to plausible assumptions of past population structures to suggest prevalence in the past. Results: Dementia prevalence […]
Eisai submits EMA application of in-house developed lenvatinib for renal cell carcinoma
fasoladaellinikiστοOTOLARYNGOLOGY LIFELONG LEARNING : OTOLARYNGOLOGY BY ALEXANDROS SFAKIANAKIS,GREECE CRETE,ANAPAFSEOS 5 AGIOS NIKOLAOS 72100,TEL : 00302841026182,00306932607174Πριν από 14 δευτερόλεπτα
The number of patients with renal cancer in Europe is estimated to be 115,000,1 and renal cell carcinoma comprises more than 90% of all malignancies of the kidney.2 For advanced or metastatic renal cell carcinoma that is difficult to treat with surgery, the standard treatment method is molecular targeted drug therapy, however with low 5-year […]
Predictors of early androgen deprivation treatment failure in prostate cancer with bone metastases
fasoladaellinikiστοOTOLARYNGOLOGY LIFELONG LEARNING : OTOLARYNGOLOGY BY ALEXANDROS SFAKIANAKIS,GREECE CRETE,ANAPAFSEOS 5 AGIOS NIKOLAOS 72100,TEL : 00302841026182,00306932607174Πριν από 14 δευτερόλεπτα
Abstract Approximately 15% of men with hormone naïve metastatic prostate cancer primarily fail to respond to androgen deprivation treatment (ADT). The reason why the response to ADT differs in this subgroup of men with prostate cancer remains unclear. The aim of this study was to describe the characteristics of these men and to thereby define […]
Does a multidisciplinary team approach in a tertiary referral centre impact on the initial management of head and neck cancer?
fasoladaellinikiστοOTOLARYNGOLOGY LIFELONG LEARNING : OTOLARYNGOLOGY BY ALEXANDROS SFAKIANAKIS,GREECE CRETE,ANAPAFSEOS 5 AGIOS NIKOLAOS 72100,TEL : 00302841026182,00306932607174Πριν από 14 δευτερόλεπτα
Publication date: Available online 13 January 2016 Source:Oral Oncology Author(s): Cristiana Bergamini, Laura Locati, Paolo Bossi, Roberta Granata, Salvatore Alfieri, Carlo Resteghini, Martina Imbimbo, Carlo Fallai, Ester Orlandi, Silvia Tana, Nicola Alessandro Iacovelli, Marco Guzzo, Tullio Ibba, Sarah Colombo, Roberto Bianchi, Natalia Pizzi, Walter Fontanella, Lisa Licitra ObjectivesA multi-disciplinary team (MDT) is essential in the […]
Driver views on speed and enforcement
fasoladaellinikiστοOTOLARYNGOLOGY LIFELONG LEARNING : OTOLARYNGOLOGY BY ALEXANDROS SFAKIANAKIS,GREECE CRETE,ANAPAFSEOS 5 AGIOS NIKOLAOS 72100,TEL : 00302841026182,00306932607174Πριν από 14 δευτερόλεπτα
Publication date: April 2016 Source:Accident Analysis & Prevention, Volume 89 Author(s): Edna Schechtman, Hillel Bar-Gera, Oren Musicant This paper reports on the results of a drivers’ survey regarding the effects of speed cameras for speed enforcement in Israel. The survey was part of a larger study that accompanied the introduction of digital speed cameras. Speed […]
Sp1-mediated ectopic expression of T-cell lymphoma invasion and metastasis 2 in hepatocellular carcinoma
fasoladaellinikiστοOTOLARYNGOLOGY LIFELONG LEARNING : OTOLARYNGOLOGY BY ALEXANDROS SFAKIANAKIS,GREECE CRETE,ANAPAFSEOS 5 AGIOS NIKOLAOS 72100,TEL : 00302841026182,00306932607174Πριν από 14 δευτερόλεπτα
Abstract T-cell lymphoma invasion and metastasis 2 (TIAM2) is a neuron-specific protein that has been found ectopically expressed in hepatocellular carcinoma (HCC). Results from clinical specimens and cellular and animal models have shown that the short form of TIAM2 (TIAM2S) functions as an oncogene in the tumorigenesis of liver cancer. However, the regulation of TIAM2S […]
Predictors of early androgen deprivation treatment failure in prostate cancer with bone metastases
fasoladaellinikiστοOTOLARYNGOLOGY LIFELONG LEARNING : OTOLARYNGOLOGY BY ALEXANDROS SFAKIANAKIS,GREECE CRETE,ANAPAFSEOS 5 AGIOS NIKOLAOS 72100,TEL : 00302841026182,00306932607174Πριν από 14 δευτερόλεπτα
Abstract Approximately 15% of men with hormone naïve metastatic prostate cancer primarily fail to respond to androgen deprivation treatment (ADT). The reason why the response to ADT differs in this subgroup of men with prostate cancer remains unclear. The aim of this study was to describe the characteristics of these men and to thereby define […]
Epithelial ovarian cancer subtypes attributable to smoking in the Norwegian Women and Cancer Study, 2012
fasoladaellinikiστοOTOLARYNGOLOGY LIFELONG LEARNING : OTOLARYNGOLOGY BY ALEXANDROS SFAKIANAKIS,GREECE CRETE,ANAPAFSEOS 5 AGIOS NIKOLAOS 72100,TEL : 00302841026182,00306932607174Πριν από 14 δευτερόλεπτα
Abstract Among European women, ovarian cancer is the fifth most common cancer. Smoking is an established risk factor for mucinous tumors. We estimated the impact of smoking in Norwegian women using population attributable fractions (PAFs) of epithelial ovarian cancer (EOC), by invasiveness and by histological subtypes in the Norwegian Women and Cancer Study with an […]
Morningness/eveningness and the synchrony effect for spatial attention
fasoladaellinikiστοOTOLARYNGOLOGY LIFELONG LEARNING : OTOLARYNGOLOGY BY ALEXANDROS SFAKIANAKIS,GREECE CRETE,ANAPAFSEOS 5 AGIOS NIKOLAOS 72100,TEL : 00302841026182,00306932607174Πριν από 14 δευτερόλεπτα
Publication date: Available online 13 January 2016 Source:Accident Analysis & Prevention Author(s): Jillian Dorrian, Benjamin McLean, Siobhan Banks, Tobias Loetscher There is evidence that a decrease in alertness is associated with a rightward shift of attention. Alertness fluctuates throughout the day and peak times differ between individuals. Some individuals feel most alert in the morning; […]
Rapid palatal expansion effects on mandibular transverse dimensions in unilateral posterior crossbite patients: a three-dimensional digital imaging study
Rapid palatal expansion effects on mandibular transverse dimensions in unilateral posterior crossbite patients: a three-dimensional digital imaging study: Background: The purpose of this controlled study was to investigate indirect effects on mandibular arch dimensions, 1 year after rapid palatal expansion (RPE) therapy. Methods: Thirty-three patients in mixed dentition (mean age 8.8 years) showing unilateral posterior crossbite and maxillary deficiency were treated with a RPE (Haas type) cemented on the first permanent molars. Treatment protocol consisted of two turns per day until ...περισσότερα »
A custom face mask for the treatment of obstructive sleep apnea
Fabrication technique for via The Journal of Prosthetic Dentistry Publication date: Available online 8 January 2016 *Source:*The Journal of Prosthetic Dentistry Author(s): Ronald S. Prehn, Tom Colquitt The development of the positive airway pressure custom mask (TAP-PAP CM) has changed the treatment of obstructive sleep apnea. The TAP-PAP CM is used in continuous positive airway pressure therapy (CPAP) and is fabricated from the impression of the face. This mask is then connected to a post screwed into the mechanism of the TAP3 (Thornton Anterior Positioner) oral appliance. This strap... περισσότερα »
Innate Immunity and Saliva in Candida albicans-mediated Oral Diseases
Innate Immunity and Saliva in Candida albicans-mediated Oral Diseases: The oral cavity is a unique niche where *Candida albicans* infections occur in immunocompetent as well as immunosuppressed individuals. Here we critically review the significance of human innate immune response in preventing oral candidiasis. One important line of defense against oropharyngeal candidiasis is the oral microbiota that prevents infection by competing for space and nutrients as well as by secreting antagonistic molecules and triggering local inflammatory responses. *C. albicans* is able to induce mu...περισσότερα »
New T. gondii genetic types: Toxoplasmosis
Toxoplasmosis in the Caribbean islands: literature review, seroprevalence in pregnant women in ten countries, isolation of viable Toxoplasma gondii from dogs from St. Kitts, West Indies with report of new T. gondii genetic types: AbstractLittle is currently known of clinical toxoplasmosis in humans and animals in the Caribbean. We investigated the prevalence of IgG and IgM antibodies in 437 pregnant women from 10 English speaking Caribbean countries. Overall, antibodies (IgG) to *Toxoplasma gondii* (modified agglutination test, MAT, cut-off 1:6) were found in 174 (39.8 %) of 437 h... περισσότερα »
Probiotic Compared with Standard Milk for High-caries Children
Probiotic Compared with Standard Milk for High-caries Children: A Cluster Randomized Trial: The aim of this study was to compare milk supplemented with probiotic lactobacilli with standard milk for the increment of caries in preschool children after 10 mo of intervention. The study was a triple-blind, placebo-controlled randomized trial. Participants were children aged 2 and 3 y (*n* = 261) attending 16 nursery schools in a metropolitan region in Chile. Nursery schools were randomly assigned to 2 parallel groups: children in the intervention group were given 150 mL of milk suppleme... περισσότερα »
Gait, bilateral coordination, and asymmetry in women with fibromyalgia
Variability of via Gait & Posture Publication date: Available online 12 January 2016 *Source:*Gait & Posture Author(s): J. Heredia-Jimenez, E. Orantes-Gonzalez, V.M. Soto-Hermoso PurposeTo analyze how fibromyalgia affected the variability, asymmetry, and bilateral coordination of gait walking at comfortable and fast speeds.Methods65 fibromyalgia (FM) patients and 50 healthy women were analyzed. Gait analysis was performed using an instrumented walkway (GAITRite system). Average walking speed, coefficient of variation (CV) of stride length, swing time, and step width data were obtained... περισσότερα »
Influence of non-spatial working memory demands on reach-grasp responses to loss of balance
: Effects of age and fall risk via Gait & Posture Publication date: Available online 12 January 2016 *Source:*Gait & Posture Author(s): Kelly P. Westlake, Brian P. Johnson, Robert A. Creath, Rachel M. Neff, Mark W. Rogers Reactive balance recovery strategies following an unexpected loss of balance are crucial to the prevention of falls, head trauma and other major injuries in older adults. While a longstanding focus has been on understanding lower limb recovery responses, the upper limbs also play a critical role. However, when a fall occurs, little is known about the role of memory a...περισσότερα »
Localization-in-noise and binaural medial olivocochlear functioning in children and young adults
Localization-in-noise and binaural medial olivocochlear functioning in children and young adults: Children as young as 5 yr old localize sounds as accurately as adults in quiet in the frontal hemifield. However, children's ability to localize in noise and in the front/back (F/B) dimension are scantily studied. To address this, the first part of this study investigated localization-in-noise ability of children vs young adults in two maskers: broadband noise (BBN) and speech-babble (SB) at three signal-to-noise ratios: −12, −6, and 0 dB. In the second part, relationship between bina... περισσότερα »
Development of Insertion Models Predicting Cochlear Implant Electrode Position.
Development of Insertion Models Predicting Cochlear Implant Electrode Position.: Objectives: To assess the possibility to define a preferable range for electrode array insertion depth and surgical insertion distance for which frequency mismatch is minimalized. To develop a surgical insertion guidance tool by which a preferred target angle can be attained using preoperative available anatomical data and surgically controllable insertion distance. Design: Multiplanar reconstructions of pre- and post-operative CT scans were evaluated in a population of 336 patients implanted with the CI... περισσότερα »
The Cost of Meniere's Disease: A Novel Multisource Approach.
The Cost of Meniere's Disease: A Novel Multisource Approach.: Objectives: To estimate the annual cost of Meniere's disease and the cost per person in the UK population and to investigate the direct and indirect costs of the condition. Design: The authors utilized a multidata approach to provide the first estimate of the cost of Meniere's. Data from the UK Biobank (a study of 500,000 individuals collected between 2007 and 2012), the Hospital Episode Statistics (data on all hospital admissions in England from 2008 to 2012) and the UK Meniere's Society (2014) were used to estimate the c...περισσότερα »
Laryngology litigation
Laryngology litigation in the United States: Thirty years in review: Objectives/Hypothesis Malpractice claims pertaining to laryngology procedures are a potentially important source of information that could be used to minimize the risk of future litigation and improve patient care. Study Design A retrospective review of two publicly available databases containing jury verdicts and settlements. Methods The LexisNexis Jury Verdicts and Settlements and WestlawNext legal databases were reviewed for all lawsuits and out-of-court adjudications related to the practice of laryngology. Data ... περισσότερα »
Congenital nasal neuroglial heterotopia and encephaloceles: An update on current evaluation and management
Congenital nasal neuroglial heterotopia and encephaloceles: An update on current evaluation and management: Objectives/Hypothesis To describe our experience and current management approach for congenital nasal neuroglial heterotopia (NGH) and encephaloceles. Study Design Retrospective chart review at a tertiary pediatric hospital from 1970 to 2013. Methods Thirty patients met inclusion criteria: 21 NGH and nine encephaloceles. Data including demographics, pathology, imaging modality, surgical approach, resection extent, outcomes, and complications were analyzed. Results Fourteen NGH ... περισσότερα »
GI-6207 in Patients With Recurrent Medullary Thyroid Cancer
A Phase 2 Study of GI-6207 in Patients With Recurrent Medullary Thyroid Cancer: *Condition*: Medullary Thyroid Cancer *Intervention*: Biological: GI-6207 *Sponsors*: National Institutes of Health Clinical Center (CC); National Institutes of Health (NIH); National Cancer Institute (NCI) This study is being done because standard therapies have not been effective in medullary thyroid cancer (MTC). The NIH research team is studying how an experimental vaccine will affect MTC. The vaccine (GI-6207) is made with yeast and designed to target cells making a protein called CEA (... περισσότερα »
A Study of Chemo +/- Low-dose Radiation as Induction Therapy in SCCHN
A Study of Chemo +/- Low-dose Radiation as Induction Therapy in SCCHN: *Conditions*: Head and Neck Cancer; Larynx *Interventions*: Radiation: Low dose fractionated radiation - 80cGy with chemotherapy; Drug: Docetaxel and Carboplatin AUC 6 *Sponsor*: University of Kentucky ArmsAssigned InterventionsExperimental: Chemotherapy plus Radiation Therapy Low dose fractionated radiation - 80cGy with chemotherapy Radiation: Low dose fractionated radiation - 80cGy with chemotherapy Chemotherapy + 80 cGy of RT Active Comparator: Chemotherapy without Radiation Chemotherapy only Drug: Do... περισσότερα »
Prospective Follow-up of Outcomes in Patients Receiving Photodynamic Therapy for Neoplastic Diseases
Prospective Follow-up of Outcomes in Patients Receiving Photodynamic Therapy for Neoplastic Diseases: *Condition*: Neoplastic Disease *Intervention*: Other: Data Collection *Sponsor*: Abramson Cancer Center of the University of Pennsylvania From 1996-present, we have used photodynamic therapy (PDT) to treat a number of neoplastic diseases both on prospective research protocols (for head and neck cancer, pleural malignancies, peritoneal carcinomatosis or sarcomatosis and prostate cancer) as well as for FDA approved and off label or compassionate exemption indications (neoplas... περισσότερα »
Impact of Symbiotic Administration on Intestinal Function of Head and Neck Patients Surgically Treated
Impact of Symbiotic Administration on Intestinal Function of Head and Neck Patients Surgically Treated: *Conditions*: Head and Neck Cancer; Synbiotics; Nutrition Therapy *Interventions*: Dietary Supplement: LactoFos; Dietary Supplement: Maltodextrin *Sponsor*: Federal University of Minas Gerais ArmsAssigned InterventionsExperimental: Symbiotic Patients will receive twice a day the symbiotic product during seven days after surgical treatment Dietary Supplement: LactoFos Patients will receive the product twice a day during seven days after surgical treatment Placebo Comp... περισσότερα »
Intrafollicular Epstein-Barr virus-positive large B cell lymphoma. A variant of “germinotropic” lymphoproliferative disorder
Intrafollicular Epstein-Barr virus-positive large B cell lymphoma. A variant of “germinotropic” lymphoproliferative disorder: AbstractGerminotropic lymphoproliferative disorders were previously described as localized disorders associated with coinfection by human herpes virus 8 and Epstein-Barr virus and characterized by good clinical outcome. We report the clinical, morphological, phenotypical, and molecular features of three cases of a hitherto unreported variant of Epstein-Barr virus (EBV)-positive, human herpes virus 8 (HHV8)-negative large B cell lymphoma with exclusive intraf... περισσότερα »
Canalolithiasis and cupulopathy using bow and lean test and head-roll test
Lateralization of horizontal semicircular canal canalolithiasis and cupulopathy using bow and lean test and head-roll test: AbstractAccurate lateralization is important to improve treatment outcomes in horizontal semicircular canal (HSCC) benign paroxysmal positional vertigo (BPPV). To determine the involved side in HSCC-BPPV, the intensity of nystagmus has been compared in a head-roll test (HRT) and the direction of nystagmus was evaluated in a bow and lean test (BLT). The aim of this study is to compare the results of a BLT with those of a HRT for lateralization of HSCC-canalolit... περισσότερα »
Lateralization of horizontal semicircular canal canalolithiasis and cupulopathy using bow and lean test and head-roll test
Lateralization of horizontal semicircular canal canalolithiasis and cupulopathy using bow and lean test and head-roll test: AbstractAccurate lateralization is important to improve treatment outcomes in horizontal semicircular canal (HSCC) benign paroxysmal positional vertigo (BPPV). To determine the involved side in HSCC-BPPV, the intensity of nystagmus has been compared in a head-roll test (HRT) and the direction of nystagmus was evaluated in a bow and lean test (BLT). The aim of this study is to compare the results of a BLT with those of a HRT for lateralization of HSCC-canalolit... περισσότερα »
Distinct vestibular phenotypes in DFNA9 families with COCH variants
Distinct vestibular phenotypes in DFNA9 families with COCH variants: AbstractMutations of *COCH* can cause hearing loss and less frequently vestibular symptoms. However, vestibular phenotypes, especially in terms of the location of specific variants are not well documented yet. In this study, a retrospective and prospective cohort survey was performed in two tertiary referral hospitals to demonstrate vestibular phenotypes of DFNA9 subjects with a focus on the relationship with the location of *COCH* mutations. Two DFNA9 subjects were recruited from the previously collected cohort, ... περισσότερα »
Lifestyle Factors and Migraine in Childhood
Lifestyle Factors and Migraine in Childhood: AbstractMigraine is one of the most common pain symptoms in children. Indeed, a high percentage of adult migraine patients report to have suffered from recurrent headache during the childhood. In particular, children could experience the so-called childhood periodic syndromes (such as cyclic vomiting, abdominal migraine, and benign paroxysmal vertigo) that have been usually considered precursors of migraine or they could develop overt migraine headaches. However, typical cohort of migraine symptoms could be absent and children could not ...περισσότερα »
Headache in Intracranial and Cervical Artery Dissections
Headache in Intracranial and Cervical Artery Dissections: AbstractDissection refers to a tear in the wall of an artery, with the two main types being intracranial or extracranial. Dissections tend to occur most commonly in the young, sometimes secondary to trauma involving the neck. To confirm a dissection, some type of vessel imaging is necessary, including magnetic resonance angiography (MRA), computed tomography angiography (CTA), or angiography. The most common presentation of a dissection (especially extracranial) is pain, usually head and neck pain along with a Horner’s syndr...περισσότερα »
Prospective cohort pilot study of 2-visit CAD/CAM monolithic complete dentures and implant-retained overdentures
Publication date: Available online 13 January 2016 *Source:*The Journal of Prosthetic Dentistry Author(s): Avinash S. Bidra, Kimberly Farrell, David Burnham, Ajay Dhingra, Thomas D. Taylor, Chia-Ling Kuo Statement of problemPresently, no studies have evaluated clinical outcomes or patient-centered outcomes for complete dentures fabricated with computer-aided design and computer aided manufacturing (CAD/CAM) technology.PurposeThe purpose of this prospective cohort pilot study was to evaluate the clinical and patient-centered outcomes for CAD/CAM monolithic dentures fabricated in 2 vi...περισσότερα »
Clinical evaluation of different desensitizing agents in home-bleaching gels
Publication date: Available online 13 January 2016 *Source:*The Journal of Prosthetic Dentistry Author(s): Jussara Karina Bernardon, Marceli Vieira Martins, Gabrielle Branco Rauber, Sylvio Monteiro Junior, Luiz Narciso Baratieri Statement of problemThe influence of different compositions of desensitizing agents in whitening gels should be evaluated.PurposeThe purpose of this clinical trial was to compare the effectiveness of 4 carbamide peroxide (CP)-based bleaching gels containing desensitizing agents regarding the degree of bleaching, tooth sensitivity, degree of participant satis... περισσότερα »
Crystals, Vol. 6, Pages 10: A Review on the Properties of Iron Aluminide Intermetallics
Alexandros G. SfakianakisστοNews in OtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 27 δευτερόλεπτα
Iron aluminides have been among the most studied intermetallics since the 1930s, when their excellent oxidation resistance was first noticed. Their low cost of production, low density, high strength-to-weight ratios, good wear resistance, ease of fabrication and resistance to high temperature oxidation and sulfurization make them very attractive as a substitute for routine stainless steel in industrial applications. Furthermore, iron aluminides allow for the conservation of less accessible and expensive elements such as nickel and molybdenum. These advantages have led to the consi... περισσότερα »
Melanoma in pregnancy: a case report and review of the literature.
Related Articles *Melanoma in pregnancy: a case report and review of the literature.* Postepy Dermatol Alergol. 2015 Dec;32(6):483-7 Authors: Wielowieyska-Szybińska DK, Spałkowska M, Wojas-Pelc A PMID: 26755917 [PubMed] from #ENT-PubMed via ola Kala on Inoreader http://ift.tt/1UQvNOn via IFTTT
Successful treatment of multiple cutaneous leiomyomas with carbon dioxide laser ablation.
Related Articles *Successful treatment of multiple cutaneous leiomyomas with carbon dioxide laser ablation.* Postepy Dermatol Alergol. 2015 Dec;32(6):480-2 Authors: Michajłowski I, Błażewicz I, Karpinsky G, Sobjanek M, Nowicki R PMID: 26755916 [PubMed] from #ENT-PubMed via ola Kala on Inoreader http://ift.tt/1UQvNxW via IFTTT
Effectiveness of omalizumab in an asthmatic patient with severe airway and blood eosinophilia.
Related Articles *Effectiveness of omalizumab in an asthmatic patient with severe airway and blood eosinophilia.* Postepy Dermatol Alergol. 2015 Dec;32(6):478-9 Authors: Kupryś-Lipińska I, Kołacińska-Flont M, Marczak J, Górski P, Kurmanowska Z, Kuna P PMID: 26755915 [PubMed] from #ENT-PubMed via ola Kala on Inoreader http://ift.tt/1UQvNht via IFTTT
Interstitial granulomatous dermatitis: a characteristic histological pattern with variable clinical manifestations.
Related Articles *Interstitial granulomatous dermatitis: a characteristic histological pattern with variable clinical manifestations.* Postepy Dermatol Alergol. 2015 Dec;32(6):475-7 Authors: Błażewicz I, Szczerkowska-Dobosz A, Pęksa R, Stawczyk-Macieja M, Barańska-Rybak W, Nowicki R PMID: 26755914 [PubMed] from #ENT-PubMed via ola Kala on Inoreader http://ift.tt/1UQvLG9 via IFTTT
Seckel syndrome with cutaneous pigmentary changes: two siblings and a review of the literature.
Related Articles *Seckel syndrome with cutaneous pigmentary changes: two siblings and a review of the literature.* Postepy Dermatol Alergol. 2015 Dec;32(6):470-4 Authors: Kilic A, Çakmak SK, Tuncali T, Koz O, Ozhamamci E, Yasun O, Artuz F PMID: 26755913 [PubMed] from #ENT-PubMed via ola Kala on Inoreader http://ift.tt/1UQvLpL via IFTTT
Quality of life in patients with leg ulcers or skin lesions - a pilot study.
Related Articles *Quality of life in patients with leg ulcers or skin lesions - a pilot study.* Postepy Dermatol Alergol. 2015 Dec;32(6):465-9 Authors: Szewczyk MT, Mościcka P, Jawień A, Cwajda-Białasik J, Cierzniakowska K, Ślusarz R, Hancke E Abstract INTRODUCTION: Attempts to determine the quality of life are advisable in patients with ulcers as the group affected with this problem is relatively large. According to one Polish randomized trial, approximately 0.3-2% of the adult population suffers from active or healed venous ulcers. AIM: To compare the quality of life of patient... περισσότερα »
Self-assessment of striae gravidarum prophylaxis.
Related Articles *Self-assessment of striae gravidarum prophylaxis.* Postepy Dermatol Alergol. 2015 Dec;32(6):459-64 Authors: Antoszewski B, Sobczak M, Kasielska-Trojan A Abstract INTRODUCTION: Striae are the most frequently occurring pathology of connective tissue during pregnancy. According to the statistical data, 70-90% of women suffer from striae gravidarum. AIM: To assess effectiveness of topical products and massage used by pregnant women in striae gravidarum prophylaxis. MATERIAL AND METHODS: The questionnaire study was conducted among 299 women who were maximum 6 months a... περισσότερα »
Frequency of streptococcal upper respiratory tract infections and HLA-Cw*06 allele in 70 patients with guttate psoriasis from northern Poland.
Related Articles *Frequency of streptococcal upper respiratory tract infections and HLA-Cw*06 allele in 70 patients with guttate psoriasis from northern Poland.* Postepy Dermatol Alergol. 2015 Dec;32(6):455-8 Authors: Maciejewska-Radomska A, Szczerkowska-Dobosz A, Rębała K, Wysocka J, Roszkiewicz J, Szczerkowska Z, Placek W Abstract INTRODUCTION: The association of guttate psoriasis with a streptococcal throat infection and HLA-Cw*06 allele is well established in different populations. Nevertheless, only few studies on this form of disease have been performed in the Polish popul... περισσότερα »
Optical rhinometry in nasal provocation testing.
Related Articles *Optical rhinometry in nasal provocation testing.* Postepy Dermatol Alergol. 2015 Dec;32(6):449-54 Authors: Krzych-Fałta E, Sybilski A, Wojas O, Samoliński B Abstract INTRODUCTION: Optical rhinometry (ORM) is a technique that allows for direct continuous measurement of changes in blood flow (optical density) in nasal vessels, at the same time analyzing changes per unit of time in the evaluated variable: intravascular blood flow and oxygen saturation. AIM: To assess the extent to which ORM can be used as an objective measure of nasal mucosal edema following a nasal...περισσότερα »
Concentration of angiopoietins 1 and 2 and their receptor Tie-2 in peripheral blood in patients with chronic obstructive pulmonary disease.
Related Articles *Concentration of angiopoietins 1 and 2 and their receptor Tie-2 in peripheral blood in patients with chronic obstructive pulmonary disease.* Postepy Dermatol Alergol. 2015 Dec;32(6):443-8 Authors: Kierszniewska-Stępień D, Pietras T, Ciebiada M, Górski P, Stępień H Abstract INTRODUCTION: Both angiopoietins (angiopoietin 1 - Ang-1, angiopoietin 2 - Ang-2) and angiopoietin receptors (Tie) are involved in angiogenesis and vascular remodeling. AIM: To assess concentrations of Ang-1, Ang-2 and Tie-2 in blood of patients with chronic obstructive pulmonary disease (COPD)...περισσότερα »
Expression of CXCR4 and CXCL12 and their correlations to the cell proliferation and angiogenesis in mycosis fungoides.
Related Articles *Expression of CXCR4 and CXCL12 and their correlations to the cell proliferation and angiogenesis in mycosis fungoides.* Postepy Dermatol Alergol. 2015 Dec;32(6):437-42 Authors: Maj J, Jankowska-Konsur AM, Hałoń A, Woźniak Z, Plomer-Niezgoda E, Reich A Abstract INTRODUCTION: Chemokines play an important role in tumor growth, invasion and metastasis. The CXCR4/CXCL12 axis has been implicated in development of both solid tumors and hematological malignancies and is also relevant in the pathogenesis of the most common primary cutaneous T-cell lymphoma, mycosis fung... περισσότερα »
Extrabronchial symptoms and late phase reaction enhance the diagnostic value of aspirin bronchial challenge.
Related Articles *Extrabronchial symptoms and late phase reaction enhance the diagnostic value of aspirin bronchial challenge.* Postepy Dermatol Alergol. 2015 Dec;32(6):431-6 Authors: Tworek D, Zielińska-Wyderkiewicz E, Górski P, Kuna P Abstract INTRODUCTION: Lysine aspirin (l-ASA) bronchial challenge can be used in the diagnostics of aspirin exacerbated respiratory disease. It is safer than oral challenge, however it is characterized by a lower sensitivity. AIM: We sought to investigate whether additional indicators of the positive result of l-ASA bronchial challenge, i.e. late p...περισσότερα »
The initial management of head and neck cancer
Does a multidisciplinary team approach in a tertiary referral centre impact on the initial management of head and neck cancer? via ScienceDirect Publication: Oral Oncology Publication date: Available online 13 January 2016 *Source:*Oral Oncology Author(s): Cristiana Bergamini, Laura Locati, Paolo Bossi, Roberta Granata, Salvatore Alfieri, Carlo Resteghini, Martina Imbimbo, Carlo Fallai, Ester Orlandi, Silvia Tana, Nicola Alessandro Iacovelli, Marco Guzzo, Tullio Ibba, Sarah Colombo, Roberto Bianchi, Natalia Pizzi, Walter Fontanella, Lisa Licitra ObjectivesA multi-disciplinary team (MDT...περισσότερα »
Histopathological aspects and bone destruction characteristics in acquired middle ear cholesteatoma
Analysis of histopathological aspects and bone destruction characteristics in acquired middle ear cholesteatoma of pediatric and adult patients via International Journal of Pediatric Otorhinolaryngology Publication date: Available online 13 January 2016 *Source:*International Journal of Pediatric Otorhinolaryngology Author(s): Mustafa Aslıer, Taner Kemal Erdag, Sulen Sarioglu, Enis Alpin Güneri, Ahmet Omer Ikiz, Evren Uzun, Erdener Özer ObjectiveThe aim of this study was to investigate the proliferative and apoptotic activity of middle ear cholesteatoma in pediatric and adult patients, ... περισσότερα »
Larygotracheal reconstruction in the management of recurrent croup in patients with subglottic stenosis
The role of via International Journal of Pediatric Otorhinolaryngology Publication date: Available online 13 January 2016 *Source:*International Journal of Pediatric Otorhinolaryngology Author(s): Bianca Siegel, Prasad Thottam, Deepak Mehta ObjectivesTo determine the role of laryngotracheal reconstruction for recurrent croup and evaluate surgical outcomes in this cohort of patients.MethodsRetrospective chart review at a tertiary care pediatric hospital.ResultsSix patients who underwent laryngotracheal reconstruction (LTR) for recurrent croup with underlying subglottic stenosis were id... περισσότερα »
Age differences in behavioral and neural correlates of proactive interference: Disentangling the role of overall working memory performance
[image: S10538119.gif] Publication date: 15 February 2016 *Source:*NeuroImage, Volume 127 Author(s): Sandra V. Loosli, Benjamin Rahm, Josef M. Unterrainer, Irina Mader, Cornelius Weiller, Christoph P. Kaller Reliable performance in working memory (WM) critically depends on the ability to resist proactive interference (PI) from previously relevant WM contents. Both WM performance and PI susceptibility are subject to cognitive decline at older adult age. However, the behavioral and neural processes underlying these co-evolving developmental changes and their potential interdependencie... περισσότερα »
Patch-based augmentation of Expectation–Maximization for brain MRI tissue segmentation at arbitrary age after premature birth
[image: S10538119.gif] Publication date: 15 February 2016 *Source:*NeuroImage, Volume 127 Author(s): Mengyuan Liu, Averi Kitsch, Steven Miller, Vann Chau, Kenneth Poskitt, Francois Rousseau, Dennis Shaw, Colin Studholme Accurate automated tissue segmentation of premature neonatal magnetic resonance images is a crucial task for quantification of brain injury and its impact on early postnatal growth and later cognitive development. In such studies it is common for scans to be acquired shortly after birth or later during the hospital stay and therefore occur at arbitrary gestational ag...περισσότερα »
Identification of the murine H-2D b and human HLA-A*0201 MHC class I-restricted HPV6 E7-specific cytotoxic T lymphocyte epitopes
Abstract Recurrent respiratory papillomatosis is caused by human papillomavirus (HPV) infection, most commonly types 6 (HPV-6) and 11 (HPV-11). Due to failed host immune responses, HPV is unable to be cleared from the host, resulting in recurrent growth of HPV-related lesions that can obstruct the lumen of the airway within the upper aerodigestive tract. In our murine model, the HPV-6b and HPV-11 E7 antigens are not innately immunogenic. In order to enhance the host immune responses against the HPV E7 antigen, we linked calreticulin (CRT) to HPV-6b E7 and found that vaccinating C57...περισσότερα »
Chemotherapy for Tuberculous Meningitis
Tuberculous meningitis, the most destructive form of tuberculosis, continues to be associated with considerable mortality and morbidity; among children, it is the major cause of death resulting from tuberculosis. The consequences of tuberculous meningitis are yet again clearly shown in the article… from NeuroSurgery via xlomafota13 on Inoreader http://ift.tt/1TWMqIe via IFTTT
Intensified Antituberculosis Therapy in Adults with Tuberculous Meningitis
[image: nejmoa1507062_f1.gif] Early treatment with antituberculosis chemotherapy and adjunctive treatment with glucocorticoids reduce the rate of death and disability from tuberculous meningitis, but the disease still kills or disables almost half the patients with the condition. The current guidelines recommend treatment with… from NeuroSurgery via xlomafota13 on Inoreader http://ift.tt/1Q6Zdsc via IFTTT
Relationship between Nonmedical Prescription-Opioid Use and Heroin Use
[image: nejmra1508490_f1.gif] The nonmedical use of prescription opioids is a major public health issue in the United States, both because of the overall high prevalence and because of marked increases in associated morbidity and mortality. In 2014, a total of 10.3 million persons reported using prescription opioids… from NeuroSurgery via xlomafota13 on Inoreader http://ift.tt/1Q6ZawM via IFTTT
Long-lasting deficits in hedonic and nucleus accumbens reactivity to sweet rewards by sugar overconsumption during adolescence
Abstract Adolescence is a critical period characterized by major neurobiological changes. Chronic stimulation of the reward system might constitute an important factor in vulnerability to pathological development. In spite of the dramatic increase in the consumption of sweet palatable foods during adolescence in our modern societies, the long-term consequences of such exposure on brain reward processing remain poorly understood. Here, we investigated in rats the long-lasting effects of sugar overconsumption during their adolescence on their adult reactivity to the hedonic properti... περισσότερα »
Integration of high-resolution data for temporal bone surgical simulations
Abstract Purpose To report on the state of the art in obtaining high-resolution 3D data of the microanatomy of the temporal bone and to process that data for integration into a surgical simulator. Specifically, we report on our experience in this area and discuss the issues involved to further the field. Data sources Current temporal bone image acquisition and image processing established in the literature as well as in house methodological development. Review methods We reviewed the current English literature for the techniques used in computer-based temporal bone simulation sy... περισσότερα »
A novel method for texture-mapping conoscopic surfaces for minimally invasive image-guided kidney surgery
Abstract Purpose Organ-level registration is critical to image-guided therapy in soft tissue. This is especially important in organs such as the kidney which can freely move. We have developed a method for registration that combines three-dimensional locations from a holographic conoscope with an endoscopically obtained textured surface. By combining these data sources clear decisions as to the tissue from which the points arise can be made. Methods By localizing the conoscope's laser dot in the endoscopic space, we register the textured surface to the cloud of conoscopic points. ...περισσότερα »
Corticospinal tract modeling for neurosurgical planning by tracking through regions of peritumoral edema and crossing fibers using two-tensor unscented Kalman filter tractography
Abstract Purpose The aim of this study was to present a tractography algorithm using a two-tensor unscented Kalman filter (UKF) to improve the modeling of the corticospinal tract (CST) by tracking through regions of peritumoral edema and crossing fibers. Methods Ten patients with brain tumors in the vicinity of motor cortex and evidence of significant peritumoral edema were retrospectively selected for the study. All patients underwent 3-T magnetic resonance imaging (MRI) including functional MRI (fMRI) and a diffusion-weighted data set with 31 directions. Fiber tracking was perf... περισσότερα »
Supinoxin™ Oral Administration Produces Clinically Meaningful Tumor Inhibition
In a poster presentation entitled “The Anti-Cancer Effects of Supinoxin (RX-5902) in Renal Cell Cancer,” Rexahn scientists detailed the results of several preclinical studies showing the antiproliferative effects of Supinoxin in various human renal cancer cell lines and xenograft renal cancer models.01/13/2016 (Source: Kidney Cancer Association) from #Medicine-SfakianakisAlexandros via o.lakala70 on Inoreader http://ift.tt/1KeHcC1 via IFTTT… Continue reading Supinoxin™ Oral Administration Produces Clinically Meaningful Tumor Inhibition
Genetics and Breast Cancer – Oncologists Perspectives
Abstract Breast cancer is the most common cancer in women worldwide. The clinical outcomes of which, have improved in the past decade, primarily due early diagnosis and multimodal management. Understanding of the disease biology with findings from omics-based research and molecular genetic characterization of the disease has been an important component of the therapy in… Continue reading Genetics and Breast Cancer – Oncologists Perspectives
Totally Implantable Venous Access Devices in Children Requiring Long-Term Chemotherapy: Analysis of Outcome in 122 Children from a Single Institution.
Abstract Children with malignancy require venous access that is reliable, safe and compliant on a long-term basis. There is little data available on utilization of totally implantable venous access devices (TIVAD) for long term chemotherapy in children in an Indian setting [1]. We report our long-term follow-up results of utilization of totally implantable venous access… Continue reading Totally Implantable Venous Access Devices in Children Requiring Long-Term Chemotherapy: Analysis of Outcome in 122 Children from a Single Institution.
Kidney Cancer Association Video Blog
News and features from our Pressroom in a video blog (VLOG) hosted by Carrie Konosky and Bill Bro, Co-CEOs of the Kidney Cancer Association.01/31/2016 (Source: Kidney Cancer Association) from #Medicine-SfakianakisAlexandros via o.lakala70 on Inoreader http://ift.tt/230SdTb via IFTTT from #Med Blogs by Alexandros G.Sfakianakis via Alexandros G.Sfakianakis on Inoreader http://ift.tt/1N8Snfq via IFTTT
Methylated circulating tumor DNA in blood: power in cancer prognosis and response
Circulating tumor DNA (ctDNA) in the plasma or serum of cancer patients provides an opportunity for non-invasive sampling of tumor DNA. This ‘liquid biopsy’ allows for interrogations of DNA such as quantity, chromosomal alterations, sequence mutations and epigenetic changes, and can be used to guide and improve treatment throughout the course of the disease. This… Continue reading Methylated circulating tumor DNA in blood: power in cancer prognosis and response
Eisai submits EMA application of in-house developed lenvatinib for renal cell carcinoma
The number of patients with renal cancer in Europe is estimated to be 115,000,1 and renal cell carcinoma comprises more than 90% of all malignancies of the kidney.2 For advanced or metastatic renal cell carcinoma that is difficult to treat with surgery, the standard treatment method is molecular targeted drug therapy, however with low 5-year… Continue reading Eisai submits EMA application of in-house developed lenvatinib for renal cell carcinoma
An Age Old Problem? Estimating the Impact of Dementia on Past Human Populations
Objective: To model the impact of dementia on past societies. Method: We consider multiple lines of evidence indicating elderly individuals to have been more common throughout the past than is frequently accepted. We then apply known dementia incidence/prevalence rates to plausible assumptions of past population structures to suggest prevalence in the past. Results: Dementia prevalence… Continue reading An Age Old Problem? Estimating the Impact of Dementia on Past Human Populations
Prospective evaluation of radiation-induced skin toxicity in a race/ethnically diverse breast cancer population
Abstract We evaluated predictors of radiation-induced skin toxicity in a prospective study of a tri-racial/ethnic breast cancer population. We evaluated patient demographics, tumor characteristics, and treatment variables in the first 392 patients in a prospective study assessing radiation-induced skin toxicity. Logistic regression analyses were conducted to evaluate potential predictors of skin toxicity. The study consists… Continue reading Prospective evaluation of radiation-induced skin toxicity in a race/ethnically diverse breast cancer population
Predictors of early androgen deprivation treatment failure in prostate cancer with bone metastases
Abstract Approximately 15% of men with hormone naïve metastatic prostate cancer primarily fail to respond to androgen deprivation treatment (ADT). The reason why the response to ADT differs in this subgroup of men with prostate cancer remains unclear. The aim of this study was to describe the characteristics of these men and to thereby define… Continue reading Predictors of early androgen deprivation treatment failure in prostate cancer with bone metastases
Does a multidisciplinary team approach in a tertiary referral centre impact on the initial management of head and neck cancer?
Publication date: Available online 13 January 2016 Source:Oral Oncology Author(s): Cristiana Bergamini, Laura Locati, Paolo Bossi, Roberta Granata, Salvatore Alfieri, Carlo Resteghini, Martina Imbimbo, Carlo Fallai, Ester Orlandi, Silvia Tana, Nicola Alessandro Iacovelli, Marco Guzzo, Tullio Ibba, Sarah Colombo, Roberto Bianchi, Natalia Pizzi, Walter Fontanella, Lisa Licitra ObjectivesA multi-disciplinary team (MDT) is essential in the… Continue reading Does a multidisciplinary team approach in a tertiary referral centre impact on the initial management of head and neck cancer?
Totally Implantable Venous Access Devices in Children Requiring Long-Term Chemotherapy: Analysis of Outcome in 122 Children from a Single Institution.
fasoladaellinikiστοOTOLARYNGOLOGY LIFELONG LEARNING : OTOLARYNGOLOGY BY ALEXANDROS SFAKIANAKIS,GREECE CRETE,ANAPAFSEOS 5 AGIOS NIKOLAOS 72100,TEL : 00302841026182,00306932607174Πριν από 55 δευτερόλεπτα
Abstract Children with malignancy require venous access that is reliable, safe and compliant on a long-term basis. There is little data available on utilization of totally implantable venous access devices (TIVAD) for long term chemotherapy in children in an Indian setting [1]. We report our long-term follow-up results of utilization of totally implantable venous access […]
Genetics and Breast Cancer – Oncologists Perspectives
fasoladaellinikiστοOTOLARYNGOLOGY LIFELONG LEARNING : OTOLARYNGOLOGY BY ALEXANDROS SFAKIANAKIS,GREECE CRETE,ANAPAFSEOS 5 AGIOS NIKOLAOS 72100,TEL : 00302841026182,00306932607174Πριν από 55 δευτερόλεπτα
Abstract Breast cancer is the most common cancer in women worldwide. The clinical outcomes of which, have improved in the past decade, primarily due early diagnosis and multimodal management. Understanding of the disease biology with findings from omics-based research and molecular genetic characterization of the disease has been an important component of the therapy in […]
Supinoxin™ Oral Administration Produces Clinically Meaningful Tumor Inhibition
fasoladaellinikiστοOTOLARYNGOLOGY LIFELONG LEARNING : OTOLARYNGOLOGY BY ALEXANDROS SFAKIANAKIS,GREECE CRETE,ANAPAFSEOS 5 AGIOS NIKOLAOS 72100,TEL : 00302841026182,00306932607174Πριν από 55 δευτερόλεπτα
In a poster presentation entitled “The Anti-Cancer Effects of Supinoxin (RX-5902) in Renal Cell Cancer,” Rexahn scientists detailed the results of several preclinical studies showing the antiproliferative effects of Supinoxin in various human renal cancer cell lines and xenograft renal cancer models.01/13/2016 (Source: Kidney Cancer Association) from #Medicine-SfakianakisAlexandros via o.lakala70 on Inoreader http://ift.tt/1KeHcC1 via IFTTT
Kidney Cancer Association Video Blog
fasoladaellinikiστοOTOLARYNGOLOGY LIFELONG LEARNING : OTOLARYNGOLOGY BY ALEXANDROS SFAKIANAKIS,GREECE CRETE,ANAPAFSEOS 5 AGIOS NIKOLAOS 72100,TEL : 00302841026182,00306932607174Πριν από 55 δευτερόλεπτα
News and features from our Pressroom in a video blog (VLOG) hosted by Carrie Konosky and Bill Bro, Co-CEOs of the Kidney Cancer Association.01/31/2016 (Source: Kidney Cancer Association) from #Medicine-SfakianakisAlexandros via o.lakala70 on Inoreader http://ift.tt/230SdTb via IFTTT
Eisai submits EMA application of in-house developed lenvatinib for renal cell carcinoma
fasoladaellinikiστοOTOLARYNGOLOGY LIFELONG LEARNING : OTOLARYNGOLOGY BY ALEXANDROS SFAKIANAKIS,GREECE CRETE,ANAPAFSEOS 5 AGIOS NIKOLAOS 72100,TEL : 00302841026182,00306932607174Πριν από 55 δευτερόλεπτα
The number of patients with renal cancer in Europe is estimated to be 115,000,1 and renal cell carcinoma comprises more than 90% of all malignancies of the kidney.2 For advanced or metastatic renal cell carcinoma that is difficult to treat with surgery, the standard treatment method is molecular targeted drug therapy, however with low 5-year […]
An Age Old Problem? Estimating the Impact of Dementia on Past Human Populations
fasoladaellinikiστοOTOLARYNGOLOGY LIFELONG LEARNING : OTOLARYNGOLOGY BY ALEXANDROS SFAKIANAKIS,GREECE CRETE,ANAPAFSEOS 5 AGIOS NIKOLAOS 72100,TEL : 00302841026182,00306932607174Πριν από 55 δευτερόλεπτα
Objective: To model the impact of dementia on past societies. Method: We consider multiple lines of evidence indicating elderly individuals to have been more common throughout the past than is frequently accepted. We then apply known dementia incidence/prevalence rates to plausible assumptions of past population structures to suggest prevalence in the past. Results: Dementia prevalence […]
Methylated circulating tumor DNA in blood: power in cancer prognosis and response
fasoladaellinikiστοOTOLARYNGOLOGY LIFELONG LEARNING : OTOLARYNGOLOGY BY ALEXANDROS SFAKIANAKIS,GREECE CRETE,ANAPAFSEOS 5 AGIOS NIKOLAOS 72100,TEL : 00302841026182,00306932607174Πριν από 55 δευτερόλεπτα
Circulating tumor DNA (ctDNA) in the plasma or serum of cancer patients provides an opportunity for non-invasive sampling of tumor DNA. This ‘liquid biopsy’ allows for interrogations of DNA such as quantity, chromosomal alterations, sequence mutations and epigenetic changes, and can be used to guide and improve treatment throughout the course of the disease. This […]
Predictors of early androgen deprivation treatment failure in prostate cancer with bone metastases
fasoladaellinikiστοOTOLARYNGOLOGY LIFELONG LEARNING : OTOLARYNGOLOGY BY ALEXANDROS SFAKIANAKIS,GREECE CRETE,ANAPAFSEOS 5 AGIOS NIKOLAOS 72100,TEL : 00302841026182,00306932607174Πριν από 55 δευτερόλεπτα
Abstract Approximately 15% of men with hormone naïve metastatic prostate cancer primarily fail to respond to androgen deprivation treatment (ADT). The reason why the response to ADT differs in this subgroup of men with prostate cancer remains unclear. The aim of this study was to describe the characteristics of these men and to thereby define […]
Does a multidisciplinary team approach in a tertiary referral centre impact on the initial management of head and neck cancer?
fasoladaellinikiστοOTOLARYNGOLOGY LIFELONG LEARNING : OTOLARYNGOLOGY BY ALEXANDROS SFAKIANAKIS,GREECE CRETE,ANAPAFSEOS 5 AGIOS NIKOLAOS 72100,TEL : 00302841026182,00306932607174Πριν από 55 δευτερόλεπτα
Publication date: Available online 13 January 2016 Source:Oral Oncology Author(s): Cristiana Bergamini, Laura Locati, Paolo Bossi, Roberta Granata, Salvatore Alfieri, Carlo Resteghini, Martina Imbimbo, Carlo Fallai, Ester Orlandi, Silvia Tana, Nicola Alessandro Iacovelli, Marco Guzzo, Tullio Ibba, Sarah Colombo, Roberto Bianchi, Natalia Pizzi, Walter Fontanella, Lisa Licitra ObjectivesA multi-disciplinary team (MDT) is essential in the […]
Sp1-mediated ectopic expression of T-cell lymphoma invasion and metastasis 2 in hepatocellular carcinoma
fasoladaellinikiστοOTOLARYNGOLOGY LIFELONG LEARNING : OTOLARYNGOLOGY BY ALEXANDROS SFAKIANAKIS,GREECE CRETE,ANAPAFSEOS 5 AGIOS NIKOLAOS 72100,TEL : 00302841026182,00306932607174Πριν από 55 δευτερόλεπτα
Abstract T-cell lymphoma invasion and metastasis 2 (TIAM2) is a neuron-specific protein that has been found ectopically expressed in hepatocellular carcinoma (HCC). Results from clinical specimens and cellular and animal models have shown that the short form of TIAM2 (TIAM2S) functions as an oncogene in the tumorigenesis of liver cancer. However, the regulation of TIAM2S […]
Docosahexaenoic Acid Promotes Axon Outgrowth by Translational Regulation of Tau and Collapsin Response Mediator Protein 2 Expression. Cell Biology
medicinesfakianakisστοMedicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 1 ώρα
N-3 polyunsaturated fatty acids (PUFAs) are essential for neuronal development and brain function; however, the molecular mechanisms underlying their biological effects remain unclear. Here we examined the mechanistic action of docosahexaenoic acid (DHA), the most abundant n-3 PUFA in the brain. We found that DHA treatment of cortical neurons resulted in enhanced axon outgrowth that […]
Sterbebegleitung: Was ist dem Arzt erlaubt?
medicinesfakianakisστοMedicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 1 ώρα
Auf der sicheren Seite Inmitten der Debatten um die Neuregelung der Sterbebegleitung vertritt der Münchner Medizinrechtsexperte Wolfgang Putz eine klare Position: Rechtmäßig ist, was fachlich indiziert ist und dem Willen des Patienten entspricht. from #Medicine-SfakianakisAlexandros via o.lakala70 on Inoreader http://ift.tt/1W9GVat via IFTTT Medicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174
Whole-brain MRI phenotyping in dysplasia-related frontal lobe epilepsy
medicinesfakianakisστοMedicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 1 ώρα
Objective: To perform whole-brain morphometry in patients with frontal lobe epilepsy and evaluate the utility of group-level patterns for individualized diagnosis and prognosis. Methods: We compared MRI-based cortical thickness and folding complexity between 2 frontal lobe epilepsy cohorts with histologically verified focal cortical dysplasia (FCD) (13 type I; 28 type II) and 41 closely matched […]
New Family of Ulvan Lyases Identified in Three Isolates from the Alteromonadales Order Microbiology
sfakianakisdiseasesστοHuman Diseases Medicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 1 ώρα
Ulvan is the main polysaccharide component of the Ulvales (green seaweed) cell wall. It is composed of disaccharide building blocks comprising 3-sulfated rhamnose (Rha3S) linked to either D-glucuronic acid (GlcA), L-iduronic acid (IduA) or D-xylose (Xyl). The degradation of ulvan requires ulvan lyase, which catalyses the endolytic cleavage of the glycoside bond between Rha3S and […]
Loss of alpha-Tubulin Acetylation is Associated with TGF-beta-induced Epithelial-Mesenchymal Transition Signal Transduction
sfakianakisdiseasesστοHuman Diseases Medicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 1 ώρα
The epithelial-to-mesenchymal transition (EMT) is a process by which differentiated epithelial cells reprogram gene expression, lose their junctions and polarity, reorganize their cytoskeleton, increase cell motility and assume a mesenchymal morphology. Despite the critical functions of the microtubule (MT) in cytoskeletal organization, how it participates in EMT induction and maintenance remains poorly understood. Here we […]
Characterization of the first {alpha}-(1->3) branching sucrases of GH70 family Enzymology
sfakianakisdiseasesστοHuman Diseases Medicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 1 ώρα
Leuconostoc citreum NRRL B-742 is known for years to produce a highly α-(1→3) branched dextran, for which the synthesis had never been elucidated. In this work, a gene coding for a putative α-transglucosylase of the GH70 family was identified in the reported genome of this bacteria, and functionally characterized. From sucrose alone, the corresponding recombinant […]
Docosahexaenoic Acid Promotes Axon Outgrowth by Translational Regulation of Tau and Collapsin Response Mediator Protein 2 Expression. Cell Biology
sfakianakisdiseasesστοHuman Diseases Medicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 1 ώρα
N-3 polyunsaturated fatty acids (PUFAs) are essential for neuronal development and brain function; however, the molecular mechanisms underlying their biological effects remain unclear. Here we examined the mechanistic action of docosahexaenoic acid (DHA), the most abundant n-3 PUFA in the brain. We found that DHA treatment of cortical neurons resulted in enhanced axon outgrowth that […]
In response to: Predictors for outcome of paper patch myringoplasty in patients with chronic tympanic membrane perforations
sfakianakisdiseasesστοHuman Diseases Medicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 1 ώρα
from #AlexandrosSfakianakis via Alexandros G.Sfakianakis on Inoreader http://ift.tt/1Zvqlag via IFTTT
Distinct vestibular phenotypes in DFNA9 families with COCH variants
sfakianakisdiseasesστοHuman Diseases Medicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 1 ώρα
Abstract Mutations of COCH can cause hearing loss and less frequently vestibular symptoms. However, vestibular phenotypes, especially in terms of the location of specific variants are not well documented yet. In this study, a retrospective and prospective cohort survey was performed in two tertiary referral hospitals to demonstrate vestibular phenotypes of DFNA9 subjects with a […]
Lateralization of horizontal semicircular canal canalolithiasis and cupulopathy using bow and lean test and head-roll test
sfakianakisdiseasesστοHuman Diseases Medicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 1 ώρα
Abstract Accurate lateralization is important to improve treatment outcomes in horizontal semicircular canal (HSCC) benign paroxysmal positional vertigo (BPPV). To determine the involved side in HSCC-BPPV, the intensity of nystagmus has been compared in a head-roll test (HRT) and the direction of nystagmus was evaluated in a bow and lean test (BLT). The aim of […]
Neutrophil to lymphocyte ratio in allergic rhinitis
sfakianakisdiseasesστοHuman Diseases Medicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 1 ώρα
from #AlexandrosSfakianakis via Alexandros G.Sfakianakis on Inoreader http://ift.tt/1ZvqmuX via IFTTT
Laboratory tests of headache disorders – dawn of a new era?
sfakianakisdiseasesστοHuman Diseases Medicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 1 ώρα
Context The classification of headache disorders has improved over the years, but further work is needed to develop and improve headache diagnosis within headache subtypes. The present review is a call for action to implement laboratory tests in the classification and management of primary and some secondary headaches. Background In this narrative review we present […]
Beyond engagement analytics: which online mixed-data factors predict student learning outcomes?
sfakianakisdiseasesστοHuman Diseases Medicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 1 ώρα
Abstract This mixed-method study focuses on online learning analytics, a research area of importance. Several important student attributes and their online activities are examined to identify what seems to work best to predict higher grades. The purpose is to explore the relationships between student grade and key learning engagement factors using a large sample from […]
What’s new in emergencies, trauma and shock? The tortuous path in the management of necrotizing fasciitis: Is early surgical intervention critical?
sfakianakistherapeuticsστοTherapeutics Infections Emergencies MEDICINE BY ALEXANDROS G.SFAKIANAKIS,ANAPAFSEOS 5 AGIOS NIKOLAOS,CRETE 72100,GREECE,TEL :00302841026182 & 00306932607174Πριν από 1 ώρα
Debabrata Bandyopadhyay, Jordan V Jacobs, Tanmay S Panchabhai Journal of Emergencies, Trauma, and Shock 2016 9(1):1-2 from Emergencies via Alexandros G.Sfakianakis on Inoreader http://ift.tt/1Q51PXJ via IFTTT
Abdominal injuries in communal crises: The Jos experience
sfakianakistherapeuticsστοTherapeutics Infections Emergencies MEDICINE BY ALEXANDROS G.SFAKIANAKIS,ANAPAFSEOS 5 AGIOS NIKOLAOS,CRETE 72100,GREECE,TEL :00302841026182 & 00306932607174Πριν από 1 ώρα
Emmanuel Olorundare Ojo, Kenneth N Ozoilo, Augustine Z Sule, Benjamin T Ugwu, Michael A Misauno, Bashiru O Ismaila, Solomon D Peter, Adeyinka A Adejumo Journal of Emergencies, Trauma, and Shock 2016 9(1):3-9 Background: Abdominal injuries contribute significantly to battlefield trauma morbidity and mortality. This study sought to determine the incidence, demographics, clinical features, spectrum, severity, […]
Left ventricular thrombus diagnosed by point-of-care ultrasonography
sfakianakistherapeuticsστοTherapeutics Infections Emergencies MEDICINE BY ALEXANDROS G.SFAKIANAKIS,ANAPAFSEOS 5 AGIOS NIKOLAOS,CRETE 72100,GREECE,TEL :00302841026182 & 00306932607174Πριν από 1 ώρα
Erden Erol ?nlüer, Umut Payza, Serdar Bayata, Fatih Esad Topal Journal of Emergencies, Trauma, and Shock 2016 9(1):42-43 from Emergencies via Alexandros G.Sfakianakis on Inoreader http://ift.tt/1J4bnAP via IFTTT
Does community emergency care initiative improve the knowledge and skill of healthcare workers and laypersons in basic emergency care in India?
sfakianakistherapeuticsστοTherapeutics Infections Emergencies MEDICINE BY ALEXANDROS G.SFAKIANAKIS,ANAPAFSEOS 5 AGIOS NIKOLAOS,CRETE 72100,GREECE,TEL :00302841026182 & 00306932607174Πριν από 1 ώρα
Sanjeev Bhoi, Nirmal Thakur, Pankaj Verma, Chhavi Sawhney, Sameer Vankar, Deepak Agrawal, Tejprakash Sinha Journal of Emergencies, Trauma, and Shock 2016 9(1):10-16 Background: Due to lack of training in emergency care, basic emergency care in India is still in its infancy. We designed All India Institute of Medical Sciences basic emergency care course (AIIMS BECC) […]
Luxatio erecta humeri in the swimmer’s shoulder: A combination of ligamentous laxity and motion dyskinesis
sfakianakistherapeuticsστοTherapeutics Infections Emergencies MEDICINE BY ALEXANDROS G.SFAKIANAKIS,ANAPAFSEOS 5 AGIOS NIKOLAOS,CRETE 72100,GREECE,TEL :00302841026182 & 00306932607174Πριν από 1 ώρα
Vamsi K Kancherla, Daniel S Heckman, Gregory F Carolan Journal of Emergencies, Trauma, and Shock 2016 9(1):39-40 from Emergencies via Alexandros G.Sfakianakis on Inoreader http://ift.tt/1Q51PqH via IFTTT
Cross-border firing and injury patterns
sfakianakistherapeuticsστοTherapeutics Infections Emergencies MEDICINE BY ALEXANDROS G.SFAKIANAKIS,ANAPAFSEOS 5 AGIOS NIKOLAOS,CRETE 72100,GREECE,TEL :00302841026182 & 00306932607174Πριν από 1 ώρα
Nital Gupta, Shafiq Hackla, Virendar Bhagat, Satvir Singh, Farid Hussain, Anil Gupta Journal of Emergencies, Trauma, and Shock 2016 9(1):17-21 Introduction: Cross-border firing are increasingly being common in the modern era. The injuries resulting from these low intensity conflicts are a source of anxiety among treating physicians and their respective governments. The provisions are required […]
A fatal anal impalement
sfakianakistherapeuticsστοTherapeutics Infections Emergencies MEDICINE BY ALEXANDROS G.SFAKIANAKIS,ANAPAFSEOS 5 AGIOS NIKOLAOS,CRETE 72100,GREECE,TEL :00302841026182 & 00306932607174Πριν από 1 ώρα
Fausto Fama’, Alessandra Villari, Dario Lo Presti, Maria Gioffre’-Florio Journal of Emergencies, Trauma, and Shock 2016 9(1):45-45 from Emergencies via Alexandros G.Sfakianakis on Inoreader http://ift.tt/1J4bnko via IFTTT
Early surgical intervention and its impact on patients presenting with necrotizing soft tissue infections: A single academic center experience
sfakianakistherapeuticsστοTherapeutics Infections Emergencies MEDICINE BY ALEXANDROS G.SFAKIANAKIS,ANAPAFSEOS 5 AGIOS NIKOLAOS,CRETE 72100,GREECE,TEL :00302841026182 & 00306932607174Πριν από 1 ώρα
George J Hadeed, Judith Smith, Terrence O’Keeffe, Narong Kulvatunyou, Julie L Wynne, Bellal Joseph, Randall S Friese, Thomas L Wachtel, Peter M Rhee, Ayman El-Menyar, Rifat Latifi Journal of Emergencies, Trauma, and Shock 2016 9(1):22-27 Objectives: Early diagnosis and emergent surgical debridement of necrotizing soft tissue infections (NSTIs) remains the cornerstone of care. We aimed […]
Successful resuscitation after splenic artery aneurysm rupture
sfakianakistherapeuticsστοTherapeutics Infections Emergencies MEDICINE BY ALEXANDROS G.SFAKIANAKIS,ANAPAFSEOS 5 AGIOS NIKOLAOS,CRETE 72100,GREECE,TEL :00302841026182 & 00306932607174Πριν από 1 ώρα
Andreas Frasnelli Journal of Emergencies, Trauma, and Shock 2016 9(1):38-39 from Emergencies via Alexandros G.Sfakianakis on Inoreader http://ift.tt/1mVdyMK via IFTTT
Tweeting the meeting: A comparative analysis of an Australian emergency medicine conference over four years
sfakianakistherapeuticsστοTherapeutics Infections Emergencies MEDICINE BY ALEXANDROS G.SFAKIANAKIS,ANAPAFSEOS 5 AGIOS NIKOLAOS,CRETE 72100,GREECE,TEL :00302841026182 & 00306932607174Πριν από 1 ώρα
Cristian Udovicich, Anthony Barberi, Kalpa Perera Journal of Emergencies, Trauma, and Shock 2016 9(1):28-31 Objective: Social media allows user-generated content and dialog between users and has also entered into the domain of healthcare. The purpose of this study was to compare the use of Twitter at the Australasian College of Emergency Medicine Annual Scientific Meeting […]
Auricular ossification: A newly recognized feature of osteoprotegerin-deficiency juvenile Paget disease
We report auricular ossification (AO) affecting the elastic cartilage of the ear as a newly recognized feature of osteoprotegerin (OPG)-deficiency juvenile Paget disease (JPD). AO and auricular calcification refer interchangeably to rigid pinnae, sparing the ear lobe, from various etiologies. JPD is a rare Mendelian disorder characterized by elevated serum alkaline phosphatase activity accompanied by skeletal pain and deformity from rapid bone turnover. Autosomal recessive transmission of loss-of-function mutations within *TNFRSF11B* encoding OPG accounts for most JPD (JPD1). JPD...περισσότερα »
A nonsense mutation in CHCHD2 in a patient with Parkinson disease
While Parkinson disease (PD) was for many years regarded as a textbook example of a nongenetic disease, this view has dramatically changed over the past 2 decades with the identification of a number of genes, mutations in which cause monogenic PD. In recent years, the identification of disease genes was facilitated due to the advent… Continue reading A nonsense mutation in CHCHD2 in a patient with Parkinson disease
Early- vs late-onset subcortical vascular cognitive impairment
Objective: To evaluate the differences between early-onset subcortical vascular cognitive impairment (EO-SVCI) and late-onset subcortical vascular cognitive impairment (LO-SVCI) with regard to pathologic burden, structural changes, and cognitive function. Methods: We prospectively recruited 142 patients from a single referral center. Patients were divided into EO-SVCI (n = 30, age at onset <65 years) and LO-SVCI… Continue reading Early- vs late-onset subcortical vascular cognitive impairment
Does a multidisciplinary team approach in a tertiary referral centre impact on the initial management of head and neck cancer?
Head and neck cancer (HNC) ranks fifth among the most common neoplasms, with >500.000 new cases diagnosed every year [1]. HNC comprises a group of malignant tumours located in the upper aero-digestive tract which show similar biological behaviour. The classification of HNC can be based on the anatomic sites of origin (i.e. nasopharynx, nasal cavity,… Continue reading Does a multidisciplinary team approach in a tertiary referral centre impact on the initial management of head and neck cancer?
The Time Intensity of Childcare Provided by Older Immigrant Women in the United States
Older adults comprise an increasing share of new legal admits to the United States. While many are financially dependent on their families, a more complete picture requires taking into account the nonmonetary contributions of this population. Using the American Time Use Survey, this study examines whether older recent immigrant women provide more unpaid childcare than… Continue reading The Time Intensity of Childcare Provided by Older Immigrant Women in the United States
Mandibular dysfunction as a reflection of bulbar involvement in SMA type 2 and 3
Objective: In a cross-sectional study, we aimed to determine (1) the effect of spinal muscular atrophy (SMA) type 2 and 3 on mandibular function reflected as masticatory performance, mandibular range of motion, and bite force and (2) the predictors of mandibular dysfunction. Methods: Sixty patients with SMA type 2 and 3 (mean age 32.3 years,… Continue reading Mandibular dysfunction as a reflection of bulbar involvement in SMA type 2 and 3
Gradient-based electrical conductivity imaging using MR phase
Purpose To develop a fast, practically applicable, and boundary artifact free electrical conductivity imaging method that does not use transceive phase assumption, and that is more robust against the noise. Theory Starting from the Maxwell’s equations, a new electrical conductivity imaging method that is based solely on the MR transceive phase has been proposed. Different… Continue reading Gradient-based electrical conductivity imaging using MR phase
Improved estimation of MR relaxation parameters using complex-valued data
Purpose In MR image analysis, T1, T2, and maps are generally calculated using magnitude MR data. Without knowledge of the underlying noise variance, parameter estimates at low signal to noise ratio (SNR) are usually biased. This leads to confounds in studies that compare parameters across SNRs and or across scanners. This article compares several estimation… Continue reading Improved estimation of MR relaxation parameters using complex-valued data
Photography and Documentary Film in the Making of Modern Brazil, Luciana Martins. Manchester University Press, Manchester (2013)
Publication date: Available online 13 January 2016 Source:Journal of Historical Geography Author(s): Louise Purbrick from #Medicine-SfakianakisAlexandros via o.lakala70 on Inoreader http://ift.tt/1PsJyPn via IFTTT Medicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174 from #Med Blogs by Alexandros G.Sfakianakis via Alexandros G.Sfakianakis on Inoreader http://ift.tt/1J4pdmV via IFTTT from #Med Blogs by Alexandros G.Sfakianakis via… Continue reading Photography and Documentary Film in the Making of Modern Brazil, Luci... περισσότερα »
Second-order motion compensated PRESS for cardiac spectroscopy
Purpose Second-order motion compensation for point-resolved spectroscopy (PRESS) is proposed to allow for robust single-voxel cardiac spectroscopy throughout the entire cardiac cycle and at various heart rates. Methods Bipolar FID spoiling gradient pairs compensating for first and second-order motion were designed and implemented into a cardiac-triggered PRESS sequence on a clinical MR system. A numerical… Continue reading Second-order motion compensated PRESS for cardiac spectroscopy
Highly dispersive nano-TiO 2 in situ growing on functional graphene with high photocatalytic activity
Abstract We present a novel approach to prepare highly dispersive nano-TiO2 by in situ growth on functional graphene (FG) via impregnation-hydrothermal method. The functional graphene was obtained by means of triethanolamine to modify graphene oxide. The characterization results collected by Fourier-transform infrared spectra, transmission electron microscope, X-ray diffraction, and X-ray photoelectron spectroscopy showed that nano-TiO2… Continue reading Highly dispersive nano-TiO 2 in situ growing on functional graphene with high photocatalytic activity
Mandibular dysfunction as a reflection of bulbar involvement in SMA type 2 and 3
fasoladaellinikiστοOTOLARYNGOLOGY LIFELONG LEARNING : OTOLARYNGOLOGY BY ALEXANDROS SFAKIANAKIS,GREECE CRETE,ANAPAFSEOS 5 AGIOS NIKOLAOS 72100,TEL : 00302841026182,00306932607174Πριν από 1 ώρα
Objective: In a cross-sectional study, we aimed to determine (1) the effect of spinal muscular atrophy (SMA) type 2 and 3 on mandibular function reflected as masticatory performance, mandibular range of motion, and bite force and (2) the predictors of mandibular dysfunction. Methods: Sixty patients with SMA type 2 and 3 (mean age 32.3 years, […]
Does a multidisciplinary team approach in a tertiary referral centre impact on the initial management of head and neck cancer?
fasoladaellinikiστοOTOLARYNGOLOGY LIFELONG LEARNING : OTOLARYNGOLOGY BY ALEXANDROS SFAKIANAKIS,GREECE CRETE,ANAPAFSEOS 5 AGIOS NIKOLAOS 72100,TEL : 00302841026182,00306932607174Πριν από 1 ώρα
Head and neck cancer (HNC) ranks fifth among the most common neoplasms, with >500.000 new cases diagnosed every year [1]. HNC comprises a group of malignant tumours located in the upper aero-digestive tract which show similar biological behaviour. The classification of HNC can be based on the anatomic sites of origin (i.e. nasopharynx, nasal cavity, […]
Early- vs late-onset subcortical vascular cognitive impairment
fasoladaellinikiστοOTOLARYNGOLOGY LIFELONG LEARNING : OTOLARYNGOLOGY BY ALEXANDROS SFAKIANAKIS,GREECE CRETE,ANAPAFSEOS 5 AGIOS NIKOLAOS 72100,TEL : 00302841026182,00306932607174Πριν από 1 ώρα
Objective: To evaluate the differences between early-onset subcortical vascular cognitive impairment (EO-SVCI) and late-onset subcortical vascular cognitive impairment (LO-SVCI) with regard to pathologic burden, structural changes, and cognitive function. Methods: We prospectively recruited 142 patients from a single referral center. Patients were divided into EO-SVCI (n = 30, age at onset <65 years) and LO-SVCI […]
The Time Intensity of Childcare Provided by Older Immigrant Women in the United States
fasoladaellinikiστοOTOLARYNGOLOGY LIFELONG LEARNING : OTOLARYNGOLOGY BY ALEXANDROS SFAKIANAKIS,GREECE CRETE,ANAPAFSEOS 5 AGIOS NIKOLAOS 72100,TEL : 00302841026182,00306932607174Πριν από 1 ώρα
Older adults comprise an increasing share of new legal admits to the United States. While many are financially dependent on their families, a more complete picture requires taking into account the nonmonetary contributions of this population. Using the American Time Use Survey, this study examines whether older recent immigrant women provide more unpaid childcare than […]
A nonsense mutation in CHCHD2 in a patient with Parkinson disease
fasoladaellinikiστοOTOLARYNGOLOGY LIFELONG LEARNING : OTOLARYNGOLOGY BY ALEXANDROS SFAKIANAKIS,GREECE CRETE,ANAPAFSEOS 5 AGIOS NIKOLAOS 72100,TEL : 00302841026182,00306932607174Πριν από 1 ώρα
While Parkinson disease (PD) was for many years regarded as a textbook example of a nongenetic disease, this view has dramatically changed over the past 2 decades with the identification of a number of genes, mutations in which cause monogenic PD. In recent years, the identification of disease genes was facilitated due to the advent […]
Photography and Documentary Film in the Making of Modern Brazil, Luciana Martins. Manchester University Press, Manchester (2013)
fasoladaellinikiστοOTOLARYNGOLOGY LIFELONG LEARNING : OTOLARYNGOLOGY BY ALEXANDROS SFAKIANAKIS,GREECE CRETE,ANAPAFSEOS 5 AGIOS NIKOLAOS 72100,TEL : 00302841026182,00306932607174Πριν από 1 ώρα
Publication date: Available online 13 January 2016 Source:Journal of Historical Geography Author(s): Louise Purbrick from #Medicine-SfakianakisAlexandros via o.lakala70 on Inoreader http://ift.tt/1PsJyPn via IFTTT Medicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174 from #Med Blogs by Alexandros G.Sfakianakis via Alexandros G.Sfakianakis on Inoreader http://ift.tt/1J4pdmV via IFTTT
Gradient-based electrical conductivity imaging using MR phase
fasoladaellinikiστοOTOLARYNGOLOGY LIFELONG LEARNING : OTOLARYNGOLOGY BY ALEXANDROS SFAKIANAKIS,GREECE CRETE,ANAPAFSEOS 5 AGIOS NIKOLAOS 72100,TEL : 00302841026182,00306932607174Πριν από 1 ώρα
Purpose To develop a fast, practically applicable, and boundary artifact free electrical conductivity imaging method that does not use transceive phase assumption, and that is more robust against the noise. Theory Starting from the Maxwell’s equations, a new electrical conductivity imaging method that is based solely on the MR transceive phase has been proposed. Different […]
Highly dispersive nano-TiO 2 in situ growing on functional graphene with high photocatalytic activity
fasoladaellinikiστοOTOLARYNGOLOGY LIFELONG LEARNING : OTOLARYNGOLOGY BY ALEXANDROS SFAKIANAKIS,GREECE CRETE,ANAPAFSEOS 5 AGIOS NIKOLAOS 72100,TEL : 00302841026182,00306932607174Πριν από 1 ώρα
Abstract We present a novel approach to prepare highly dispersive nano-TiO2 by in situ growth on functional graphene (FG) via impregnation-hydrothermal method. The functional graphene was obtained by means of triethanolamine to modify graphene oxide. The characterization results collected by Fourier-transform infrared spectra, transmission electron microscope, X-ray diffraction, and X-ray photoelectron spectroscopy showed that nano-TiO2 […]
Improved estimation of MR relaxation parameters using complex-valued data
fasoladaellinikiστοOTOLARYNGOLOGY LIFELONG LEARNING : OTOLARYNGOLOGY BY ALEXANDROS SFAKIANAKIS,GREECE CRETE,ANAPAFSEOS 5 AGIOS NIKOLAOS 72100,TEL : 00302841026182,00306932607174Πριν από 1 ώρα
Purpose In MR image analysis, T1, T2, and maps are generally calculated using magnitude MR data. Without knowledge of the underlying noise variance, parameter estimates at low signal to noise ratio (SNR) are usually biased. This leads to confounds in studies that compare parameters across SNRs and or across scanners. This article compares several estimation […]
Co-based ternary nanocomposites: synthesis and their superior performances for hydrogenation of p -nitrophenol and adsorption for methyl blue
fasoladaellinikiστοOTOLARYNGOLOGY LIFELONG LEARNING : OTOLARYNGOLOGY BY ALEXANDROS SFAKIANAKIS,GREECE CRETE,ANAPAFSEOS 5 AGIOS NIKOLAOS 72100,TEL : 00302841026182,00306932607174Πριν από 1 ώρα
Abstract A new kind of Co-based ternary nanocomposites has been obtained via one step without any additional surfactant at zero centigrade degree. Some experimental parameters play crucial roles in determining the morphologies and homogeneity of the final products, such as reaction temperature and the introduction of Na2S2O3·5H2O. The samples were characterized by XRD, SEM, TEM, […]
Syphilitic orchitis mimicking a testicular tumor in a clinically occult HIV-infected young man: a case report with emphasis on a challenging pathological diagnosis
Background: Syphilitic orchitis is a rare manifestation of gumma in tertiary syphilis, microscopically typically characterized by multiple discrete granulomas with central necrosis and peripheral fibrosis. We report a case of syphilitic orchitis mimicking a testicular tumor with atypical histological features.Case presentationA 33-year-old clinically occult HIV-infected man had a testicular tumor. A radical orchiectomy was performed, and a histological examination showed an acute and chronic interstitial inflammatory lesion as well as spindle cell proliferation, without typical gu... περισσότερα »
MSG-Evoked c-Fos Activity in the Nucleus of the Solitary Tract Is Dependent upon Fluid Delivery and Stimulation Parameters
The marker of neuronal activation, c-Fos, can be used to visualize spatial patterns of neural activity in response to taste stimulation. Because animals will not voluntarily consume aversive tastes, these stimuli are infused directly into the oral cavity via intraoral cannulae, whereas appetitive stimuli are given in drinking bottles. Differences in these 2 methods make comparison of taste-evoked brain activity between results that utilize these methods problematic. Surprisingly, the intraoral cannulae experimental conditions that produce a similar pattern of c-Fos activity in res... περισσότερα »
Smaller Dentate Gyrus and CA2 and CA3 Volumes Are Associated with Kynurenine Metabolites in Collegiate Football Athletes
Journal of Neurotrauma , Vol. 0, No. 0. from Neurology via xlomafota13 on Inoreader http://ift.tt/1Q6YQ0Z via IFTTT
Health and economic benefits of public financing of epilepsy treatment in India: An agent-based simulation model
[image: cover.gif?v=1&s=86d3aef2ad3355d25bd62fb1] Summary Objective An estimated 6–10 million people in India live with active epilepsy, and less than half are treated. We analyze the health and economic benefits of three scenarios of publicly financed national epilepsy programs that provide: (1) first-line antiepilepsy drugs (AEDs), (2) first- and second-line AEDs, and (3) first- and second-line AEDs and surgery. Methods We model the prevalence and distribution of epilepsy in India using IndiaSim, an agent-based, simulation model of the Indian population. Agents in the model a... περισσότερα »
The Neonatal CD8+ T Cell Repertoire Rapidly Diversifies during Persistent Viral Infection IMMUNE REGULATION
medicinesfakianakisστοMedicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 2 ώρες
CMV is the most common congenital infection in the United States. The major target of congenital CMV is the brain, with clinical manifestations including mental retardation, vision impairment, and sensorineural hearing loss. Previous reports have shown that CD8+ T cells are required to control viral replication and significant numbers of CMV-specific CD8+ T cells persist […]
60 YEARS OF POMC: From the prohormone theory to proopiomelanocortin and to proprotein convertases (PCSK1 to PCSK9)
medicinesfakianakisστοMedicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 2 ώρες
POMC, pro-opio-melano-cortin, is a polyprotein expressed in the pituitary and the brain where it is proteolytically processed into peptide hormones and neuropeptides with distinct biological activities. It is the prototype of multipotent prohormones. The prohormone theory was first suggested in 1967 when Chrétien and Li discovered -lipotropin (-LPH) and observed that a) it was part […]
How Are Moral Foundations Associated with Climate-Friendly Consumption?
medicinesfakianakisστοMedicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 2 ώρες
Abstract We examined whether differences in climate-friendly choices between the supporters of left-wing and right-wing ideologies are based on different moral foundations. Moreover, we compared general and issue-specific endorsement of moral foundations applied to climate change. Study 1 examined the endorsement of general moral foundations of university students living in Finland (N = 272). Individualizing […]
Alternative splicing within the Wnt signaling pathway: role in cancer development
medicinesfakianakisστοMedicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 2 ώρες
Abstract Background The Wnt signaling cascade plays a fundamental role in embryonic development, adult tissue regeneration, homeostasis and stem cell maintenance. Abnormal Wnt signaling has been found to be prevalent in various human cancers. Also, a role of Wnt signaling in the regulation of alternative splicing of several cancer-related genes has been established. In addition, […]
Ibrutinib for mantle cell lymphoma
medicinesfakianakisστοMedicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 2 ώρες
Future Oncology Ahead of Print. from #Medicine-SfakianakisAlexandros via o.lakala70 on Inoreader http://ift.tt/1OjmbtW via IFTTT Medicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174
177Lu-DOTA0,Tyr3-octreotate in the treatment of midgut neuroendocrine tumors
medicinesfakianakisστοMedicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 2 ώρες
Future Oncology Ahead of Print. from #Medicine-SfakianakisAlexandros via o.lakala70 on Inoreader http://ift.tt/1OjmdSz via IFTTT Medicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174
EM Talk: communication skills training for emergency medicine patients with serious illness
medicinesfakianakisστοMedicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 2 ώρες
The emergency department visit for a patient with serious illness represents a sentinel event, signalling a change in the illness trajectory. By better understanding patient and family wishes, emergency physicians can reinforce advance care plans and ensure the hospital care provided matches the patient’s values. Despite their importance in care at the end of life, […]
Does a multidisciplinary team approach in a tertiary referral centre impact on the initial management of head and neck cancer?
medicinesfakianakisστοMedicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 2 ώρες
Head and neck cancer (HNC) ranks fifth among the most common neoplasms, with >500.000 new cases diagnosed every year [1]. HNC comprises a group of malignant tumours located in the upper aero-digestive tract which show similar biological behaviour. The classification of HNC can be based on the anatomic sites of origin (i.e. nasopharynx, nasal cavity, […]
The Time Intensity of Childcare Provided by Older Immigrant Women in the United States
medicinesfakianakisστοMedicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 2 ώρες
Older adults comprise an increasing share of new legal admits to the United States. While many are financially dependent on their families, a more complete picture requires taking into account the nonmonetary contributions of this population. Using the American Time Use Survey, this study examines whether older recent immigrant women provide more unpaid childcare than […]
Photography and Documentary Film in the Making of Modern Brazil, Luciana Martins. Manchester University Press, Manchester (2013)
medicinesfakianakisστοMedicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 2 ώρες
Publication date: Available online 13 January 2016 Source:Journal of Historical Geography Author(s): Louise Purbrick from #Medicine-SfakianakisAlexandros via o.lakala70 on Inoreader http://ift.tt/1PsJyPn via IFTTT Medicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174
The relationship between a patient's Angle type of occlusion and recorded Bennett angle values
Publication date: Available online 13 January 2016 *Source:*The Journal of Prosthetic Dentistry Author(s): Samir Cimić, Sonja Kraljević Simunković, Amir Catić Statement of problemThe Bennett angle can be an important parameter to accurately record and program into an articulator during restorative procedures. Few data exist regarding the impact and association of a patient's occlusion types on their recorded Bennett angle values.PurposeThe purpose of this in vivo study was to investigate the effect of a patient's occlusion type on recorded Bennett angle values.Material and methodsThi...περισσότερα »
Fixation of a severely resorbed mandible for complete arch screw-retained rehabilitation: A clinical report
Publication date: Available online 13 January 2016 *Source:*The Journal of Prosthetic Dentistry Author(s): Vinicius Fabris, Atais Bacchi Severely resorbed mandibles with placed endosteal dental implants can fracture. Therefore, techniques to reduce the risk or minimize the consequences of these fractures are needed. This clinical report presents a technique for placing a titanium plate in a severely resorbed mandible subjected to complete-arch implant therapy. The titanium plate is placed in the same surgical procedure as the implants, allowing immediate implant loading. This techni... περισσότερα »
Technique for fabricating individualized dentures with a gingiva-shade composite resin
Publication date: Available online 13 January 2016 *Source:*The Journal of Prosthetic Dentistry Author(s): Beom-Woo Park, Nam-Jin Kim, Jonghyuk Lee, Hae-Hyoung Lee More natural dental esthetics have been sought by patients who wear conventional complete or partial dentures. Recently, gingiva-shade composite resins (GSCRs) have become available for replicating soft tissue for both fixed and removable prostheses. The technique presented is for fabricating individualized complete dentures. First the acrylic resin is mixed with a coloring agent and processed to modify the base shade of t...περισσότερα »
Antimicrobial activity and properties of irreversible hydrocolloid impression materials incorporated with silver nanoparticles
Publication date: Available online 13 January 2016 *Source:*The Journal of Prosthetic Dentistry Author(s): Kishore Ginjupalli, Rama Krishna Alla, Chaitanya Tellapragada, Lokendra Gupta, Nagaraja Upadhya Perampalli Statement of problemConventional spray and the immersion disinfection of irreversible hydrocolloid impression materials may lead to dimensional changes.PurposeThe purpose of this in vitro study was to investigate the antimicrobial activity and properties of irreversible hydrocolloid impression materials incorporated with silver nanoparticles.Materials and methodsThe antimi...περισσότερα »
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