The International Classification of Functioning, Disability and Health as a Framework for Providing Patient- and Family-Centered Audiological Care for Older Adults and Their Significant Others
otolaryngologistsfakianakisστοOtoRhinoLaryngology by Sfakianakis G.Alexandros,,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,tel : 00302841026182,00306932607174Πριν από 5 δευτερόλεπτα
The International Classification of Functioning, Disability and Health as a Framework for Providing Patient- and Family-Centered Audiological Care for Older Adults and Their Significant Others: Semin Hear 2016; 37: 187-199DOI: 10.1055/s-0036-1584411 Hearing impairment is highly prevalent in the older population, and it impacts communication and quality of life for both the people with the hearing […]
Aphasia and Auditory Processing after Stroke through an International Classification of Functioning, Disability and Health Lens
otolaryngologistsfakianakisστοOtoRhinoLaryngology by Sfakianakis G.Alexandros,,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,tel : 00302841026182,00306932607174Πριν από 5 δευτερόλεπτα
Aphasia and Auditory Processing after Stroke through an International Classification of Functioning, Disability and Health Lens: Semin Hear 2016; 37: 233-246DOI: 10.1055/s-0036-1584408 Aphasia is an acquired language impairment affecting speaking, listening, reading, and writing. Aphasia occurs in about a third of patients who have ischemic stroke and significantly affects functional recovery and return to work. […]
Hearing and Cognitive Impairment and the Role of the International Classification of Functioning, Disability and Health as a Rehabilitation Framework
otolaryngologistsfakianakisστοOtoRhinoLaryngology by Sfakianakis G.Alexandros,,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,tel : 00302841026182,00306932607174Πριν από 5 δευτερόλεπτα
Hearing and Cognitive Impairment and the Role of the International Classification of Functioning, Disability and Health as a Rehabilitation Framework: Semin Hear 2016; 37: 200-215DOI: 10.1055/s-0036-1584410 The International Classification of Functioning, Disability and Health (ICF) has been applied widely in the literature to describe and differentiate the broad implications of hearing impairment (HI) and cognitive […]
Factors predisposing to worsening of sleep apnea in response to fluid overload in men
otolaryngologistsfakianakisστοOtoRhinoLaryngology by Sfakianakis G.Alexandros,,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,tel : 00302841026182,00306932607174Πριν από 5 δευτερόλεπτα
Factors predisposing to worsening of sleep apnea in response to fluid overload in men: • Pre-sleep bioimpedance measures and NC can predict susceptibility to fluid overload• Men with larger pharyngeal tissue may be more susceptible to OSA with fluid overload• Fluid overloading results in more fluid accumulation in the neck Highlights • Pre-sleep bioimpedance measures […]
Video-polysomnographic documentation of non−rapid eye movement sleep parasomnia followed by rapid eye movement sleep behavior disorder: A parasomnia overlap disorder?
otolaryngologistsfakianakisστοOtoRhinoLaryngology by Sfakianakis G.Alexandros,,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,tel : 00302841026182,00306932607174Πριν από 5 δευτερόλεπτα
Video-polysomnographic documentation of non−rapid eye movement sleep parasomnia followed by rapid eye movement sleep behavior disorder: A parasomnia overlap disorder?: Parasomnia overlap disorder (POD) is the coexistence of non−rapid eye movement (NREM) parasomnia (eg, sleepwalking, confusional arousals) and rapid eye movement (REM) sleep behavior disorder (RBD) in the same individual [1]. POD can be idiopathic […]
Catathrenia, a REM predominant disorder of arousal?
otolaryngologistsfakianakisστοOtoRhinoLaryngology by Sfakianakis G.Alexandros,,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,tel : 00302841026182,00306932607174Πριν από 5 δευτερόλεπτα
Catathrenia, a REM predominant disorder of arousal?: • Catathrenia is an uncommon sleep disorder with a characteristic breathing pattern, often accompanied by groaning.• It usually arises from REM sleep and is generally preceded by an arousal from sleep.• While generally considered a social nuisance, a high proportion of catathrenia patients also report daytime sleepiness.• CPAP […]
Mast cell–mediated host defense, pseudoallergic drug reactions, and chronic inflammatory diseases
otolaryngologistsfakianakisστοOtoRhinoLaryngology by Sfakianakis G.Alexandros,,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,tel : 00302841026182,00306932607174Πριν από 5 δευτερόλεπτα
Roles of Mas-related G protein–coupled receptor X2 on mast cell–mediated host defense, pseudoallergic drug reactions, and chronic inflammatory diseases: Mast cells (MCs), which are granulated tissue-resident cells of hematopoietic lineage, contribute to vascular homeostasis, innate/adaptive immunity, and wound healing. However, MCs are best known for their roles in allergic and inflammatory diseases, such as anaphylaxis, […]
Sinus pericranii, petrosquamosal sinus and extracranial sigmoid sinus: Anatomical variations to consider during a retroauricular approach
otolaryngologistsfakianakisστοOtoRhinoLaryngology by Sfakianakis G.Alexandros,,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,tel : 00302841026182,00306932607174Πριν από 5 δευτερόλεπτα
Sinus pericranii, petrosquamosal sinus and extracranial sigmoid sinus: Anatomical variations to consider during a retroauricular approach: Lateral and sigmoid sinus malformations are uncommon and dangerous anatomical variations that surgeons may encounter when performing a retroauricular approach. We report three cases of rare temporal bone venous sinus anomalies seen in patients who underwent cochlear implant surgery. […]
DNA methylation markers for oral pre-cancer progression
otolaryngologistsfakianakisστοOtoRhinoLaryngology by Sfakianakis G.Alexandros,,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,tel : 00302841026182,00306932607174Πριν από 5 δευτερόλεπτα
Corrigendum to “DNA methylation markers for oral pre-cancer progression: A critical review” [Oral Oncology 53 (2015) 1–9]: The authors regret the error published in Introduction Section on Page 1, Line 7: “Over a million new cases are reported every year from more developed regions of the World [1], more so among young adults [4,5]”. Please […]
Majantol Is a Relevant Fragrance Allergy in Adolescent Children
otolaryngologistsfakianakisστοOtoRhinoLaryngology by Sfakianakis G.Alexandros,,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,tel : 00302841026182,00306932607174Πριν από 5 δευτερόλεπτα
Majantol Is a Relevant Fragrance Allergy in Adolescent Children: http://ift.tt/29PnNg4
Disparities in HIV clinic care across Europe: findings from the EuroSIDA clinic survey
Although advances in HIV medicine have yielded increasingly better treatment outcomes in recent years, HIV-positive people with access to antiretroviral therapy (ART) still face complex health challenges. The ... from Infection via ola Kala on Inoreader http://ift.tt/29VW6r9 via IFTTT
Sinus pericranii, petrosquamosal sinus and extracranial sigmoid sinus: Anatomical variations to consider during a retroauricular approach
Sinus pericranii, petrosquamosal sinus and extracranial sigmoid sinus: Anatomical variations to consider during a retroauricular approach: Lateral and sigmoid sinus malformations are uncommon and dangerous anatomical variations that surgeons may encounter when performing a retroauricular approach. We report three cases of rare temporal bone venous sinus anomalies seen in patients who underwent cochlear implant surgery. The first patient had a diagnosis of CHARGE syndrome and presented a bilateral persistent petrosquamosal sinus with sigmoid sinus agenesis, which made mastoidectomy f... περισσότερα »
DNA methylation markers for oral pre-cancer progression
Corrigendum to “DNA methylation markers for oral pre-cancer progression: A critical review” [Oral Oncology 53 (2015) 1–9]: The authors regret the error published in Introduction Section on Page 1, Line 7: “Over a million new cases are reported every year from more developed regions of the World [1], more so among young adults [4,5]”. Please note the corrected statement with respect to the above mentioned line: “Over a hundred thousand new cases are reported every year from more developed regions of the World [1], more so among young adults [4,5]”.
Majantol Is a Relevant Fragrance Allergy in Adolescent Children
Majantol Is a Relevant Fragrance Allergy in Adolescent Children:
Essential Oils: Emerging “Medicaments”
Essential Oils: Emerging “Medicaments”
Essential Oils Contact Allergy
Essential Oils, Part IV: Contact Allergy: Nearly 80 essential oils (including 2 jasmine absolutes) have caused contact allergy. Fifty-five of these have been tested in consecutive patients suspected of contact dermatitis, and nine (laurel, turpentine, orange, tea tree, citronella, ylang-ylang, sandalwood, clove, and costus root) showed greater than 2% positive patch test reactions. Relevance data are generally missing or inadequate. Most reactions are caused by application of pure oils or high-concentration products. The clinical picture depends on the responsible product. Occupati... περισσότερα »
Contact Dermatitis to Formaldehyde From Kissing a Corpse?
Contact Dermatitis to Formaldehyde From Kissing a Corpse?:
Current Quality-of-Life Tools Available for Use in Contact Dermatitis
Current Quality-of-Life Tools Available for Use in Contact Dermatitis: Contact dermatitis is a common dermatologic condition that can cause significant impairment in patients’ overall quality of life (QoL). This impact is separate and potentially more clinically relevant than one’s disease “severity” in contact dermatitis and should be consistently addressed by dermatologists. Despite this, QoL tools specific to contact dermatitis are lacking, and there is little consistency in the literature regarding the tool used to evaluate clinical response to therapies. Measurements currently... περισσότερα »
American Contact Dermatitis Society Contact Allergy Management Program App
American Contact Dermatitis Society Contact Allergy Management Program App:
A Pragmatic Approach to Patch Testing Atopic Dermatitis Patients
: Clinical Recommendations Based on Expert Consensus Opinion: Allergic contact dermatitis (ACD) may complicate the clinical course of atopic dermatitis (AD), and patch testing remains the criterion standard for diagnosing ACD. To date, there have been no guidelines or consensus recommendations on when and how to patch test individuals with AD. Failure to patch test when appropriate may result in overlooking an important and potentially curable complicating comorbidity. In this article, we present consensus recommendations regarding when to perform patch testing in the AD patient, be... περισσότερα »
Sensitization to Rubber Accelerators : The Triveneto Patch Test Database
Sensitization to Rubber Accelerators in Northeastern Italy: The Triveneto Patch Test Database: [image: image]Background: Natural and synthetic rubbers containing rubber accelerators are well-known causes of occupational skin disease. Allergic contact dermatitis caused by rubber gloves is frequent and has almost exclusively been attributed to contact sensitization to accelerators. Objective: This study aimed to evaluate the frequency of rubber accelerators sensitization in the population living in northeastern Italy, to find time trend and a correlation with occupations, and to inves... περισσότερα »
Vapor Pressure and Predicted Stability of American Contact Dermatitis Society Core Allergens
Vapor Pressure and Predicted Stability of American Contact Dermatitis Society Core Allergens: Background: Accurate patch testing is reliant on proper preparation of patch test allergens. The stability of patch test allergens is dependent on several factors including vapor pressure (VP). Objective: This investigation reviews the VP of American Contact Dermatitis Society Core Allergens and compares stability predictions based on VP with those established through clinical testing. Methods: Standard references were accessed for determining VP in millimeters of mercury and associated t... περισσότερα »
A Patch Test–Positive Titanium Hypersensitivity Reaction
A Patch Test–Positive Titanium Hypersensitivity Reaction
Leather Contains Cobalt and Poses a Risk of Allergic Contact Dermatitis: Cobalt Indicator Solution and X-ray Florescence Spectrometry as Screening Tests
Leather Contains Cobalt and Poses a Risk of Allergic Contact Dermatitis: Cobalt Indicator Solution and X-ray Florescence Spectrometry as Screening Tests: Background: Cobalt was recently identified in a leather couch responsible for dermatitis. Cobalt content/release in leather in the United States is unknown. We evaluated leather for cobalt content/release and investigated screening methods for identifying cobalt in leather. Methods: One hundred thirty-one leather swatches were screened for cobalt content/release with X-ray fluorescence (XRF) spectrometry and cobalt indicator soluti... περισσότερα »
Contact Urticaria From Occupational Exposure to Formaldehyde
Contact Urticaria From Occupational Exposure to Formaldehyde:
Cement-Induced Chromate Occupational Allergic Contact Dermatitis
Cement-Induced Chromate Occupational Allergic Contact Dermatitis: [image: image] Background: Hexavalent chromium in cement is a common cause of occupational allergic contact dermatitis (OACD). Methods: Analysis of patch test data during 1999 to 2013 was done. Patients with cement-induced chromate OACD filled the Dermatology Life Quality Index, graded 1 to 5. Results: Of 4846 consecutive patients who were patch tested, 146 (3%) were chromate-sensitive. Of 46 (31.5%) who presented with chromate OACD, 27 (59%) had cement-induced chromate OACD. The proportion of chromate-sensitive pat... περισσότερα »
Utilization and Geographic Variation of Patch Testing Among Medicare Beneficiaries
Utilization and Geographic Variation of Patch Testing Among Medicare Beneficiaries:
Amalgam Contact Allergy in Oral Lichenoid Lesions
Amalgam Contact Allergy in Oral Lichenoid Lesions: Abstract Background: Oral lichenoid lesions (OLLs) cannot be distinguished from oral lichen planus (OLP) except that causative factors can be identified. Amalgam is one of the causative allergens, and replacement may lead to resolution. Objectives: The aim of this study was to determine the prevalence, prognosis, and aggravating factors of amalgam contact allergy in patients with OLLs. Methods: A clinical retrospective and prospective cohort study was carried out at the Dermatology Department, Siriraj Hospital, Mahidol University... περισσότερα »
‘Cytology-on-a-chip’ based sensors for monitoring of potentially malignant oral lesions
‘Cytology-on-a-chip’ based sensors for monitoring of potentially malignant oral lesions: It is estimated that 1–2% of adults in the United States present with a worrisome white or red patch or other potentially malignant oral lesion (PMOL) during a routine oral examination [1]. However, the vast majority of these lesions are benign, and only 1–2% will undergo progression into oral squamous cell carcinoma (OSCC) [2,3]. Oral healthcare providers are often the first line of defense in the early detection of oral cancer and are faced with the challenge of recognizing PMOL and deciding w... περισσότερα »
Transoral robotic surgery: The radiation oncologist’s perspective
Transoral robotic surgery: The radiation oncologist’s perspective: Surgery has been the cornerstone in the curative management of head and neck cancer for centuries [1]. Over the past 40years, however, non-operative management has become the most common therapy for cancers of the larynx and pharynx due to advances in radiotherapy technique and the significant functional deficits left by traditional surgical approaches. The efficacy and safety of non-operative therapy in head and neck cancer has been established by multiple large phase III trials [2–6]. However, over the past decade, ... περισσότερα »
The Management of Locally Invasive Primary Thyroid Paraganglioma
The Ma A Case Report and Review of the Literature: AbstractParagangliomas (PG) are very rare neuroendocrine tumours, arising from neural crest derived paraganglia of the autonomic nervous system. Primary thyroid paraganglioma (PTPG) is a rare site of PG and only 45 cases have been previously reported. The preoperative diagnosis of PTPGs presents a challenge as the clinical, cytological and histological features overlap with more common primary thyroid cancers. A 55 year old male was found to have significant enlargement of the left lobe of his thyroid. Following lobectomy, the thyr... περισσότερα »
Selective laser melting of titanium alloy enables osseointegration of porous multi-rooted implants in a rabbit model
Osseointegration refers to the direct connection between living bone and the surface of a load-bearing artificial implant. Porous implants with well-controlled porosity and pore size can enhance osseointegrati... from Biomedical Engineering via xlomafota13 on Inoreader http://ift.tt/2aiMVQS via IFTTT
Selective laser melting of titanium alloy enables osseointegration of porous multi-rooted implants in a rabbit model
Osseointegration refers to the direct connection between living bone and the surface of a load-bearing artificial implant. Porous implants with well-controlled porosity and pore size can enhance osseointegrati... from Biomedical Engineering via ola Kala on Inoreader http://ift.tt/2aiMVQS via IFTTT
Catalytic One-Pot Diastereoselective Michael-Initiated Ring-Closure of Methyl Ketones with 3-Bromochromones: Synthesis of Cyclopropa[b]chromanones
A one-pot diastereoselective base-catalyzed Michael-initiated ring-closure (MIRC) of activated methyl ketones with 3-bromochromones to give cyclopropa[ *b*]chromanones is described. Three asymmetric centres are generated in the new cyclopropa[*b*]chromanone skeleton. Stereochemistry studies based on NMR spectroscopy and single-crystal X-ray diffraction analysis revealed the *trans* configuration of the cyclopropane ring, with the (1*R*,1a*S*,7a*R* )/(1*S*,1a*R*,7a*S*) pair of enantiomers, as was further confirmed by chiral HPLC. The use of acetone in our reaction produced a 1-acety... περισσότερα »
Stellenwert der autologen Fetttransplantation in der ästhetischen Chirurgie des Mammakarzinoms
στοOtoRhinoLaryngology - Head and Neck SurgeryΠριν από 32 δευτερόλεπτα
Zusammenfassung Die autologe Fetttransplantation gilt als sekundär rekonstruktives Verfahren und hat als Therapieziel eine Verbesserung der Lebensqualität. Beim Lipofilling wird autologes Fett in den Empfängersitus übertragen, um die Weichteilkontur der Empfängerregion zu optimieren. Brustkrebs ist die häufigste Krebserkrankung der Frau. Dank individualisierter Behandlungsmethoden steigen zwar die Heilungsraten, aber immer mehr Frauen müssen viele Jahre mit den Ergebnissen und Folgen der Operation leben. Auch wenn die Operationsverfahren immer differenzierter und an den individuell... περισσότερα »
Sinonasal Inflammatory Myofibroblastic Tumor with Anaplastic Lymphoma Kinase 1 Rearrangement: Case Study and Literature Review
στοOtoRhinoLaryngology - Head and Neck SurgeryΠριν από 32 δευτερόλεπτα
Abstract Inflammatory myofibroblastic tumors (IMTs) are rare mesenchymal tumors initially described in the lung. About half of them exhibit expression of the ALK1 protein, generally resulting from a gene rearrangement. Paranasal sinus IMTs are extremely uncommon, and gene rearrangement of ALK1 is very rare in this localization. A 47-year-old woman presented with rapidly progressive vision loss in her left eye. Clinical and imaging work-up revealed a tumor invading the left ethmoidal and sphenoidal sinuses and extending into the nasal cavity, the orbit and the skull base. Complete ... περισσότερα »
Care for head and neck cancer doesn’t end in hospital – UQ News
sfakianakisdiseasesστοHuman Diseases Medicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 35 δευτερόλεπτα
UQ News Care for head and neck cancer doesn’t end in hospital UQ News Ahead of World Head and Neck Cancer Day on 27 July, University of Queensland School of Dentistry researcher Kelsey Pateman wants to turn the spotlight to the psychological and social care needs of survivors. “One of the reasons this is becoming […]
For a New Generation of Objective Indicators in Governance and Corruption Studies
sfakianakisdiseasesστοHuman Diseases Medicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 35 δευτερόλεπτα
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Comparison of Diaphragmatic Breathing Exercise, Volume and Flow Incentive Spirometry, on Diaphragm Excursion and Pulmonary Function in Patients Undergoing Laparoscopic Surgery: A Randomized Controlled Trial
sfakianakisdiseasesστοHuman Diseases Medicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 35 δευτερόλεπτα
Objective. To evaluate the effects of diaphragmatic breathing exercises and flow and volume-oriented incentive spirometry on pulmonary function and diaphragm excursion in patients undergoing laparoscopic abdominal surgery. Methodology. We selected 260 patients posted for laparoscopic abdominal surgery and they were block randomization as follows: 65 patients performed diaphragmatic breathing exercises, 65 patients performed flow incentive […]
Prediction of Collapse Scope of Deep-Buried Tunnels Using Pressure Arch Theory
sfakianakisdiseasesστοHuman Diseases Medicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 35 δευτερόλεπτα
Tunnel collapse remains a serious problem in practice. Effective prediction methods on tunnel collapse are necessary for tunnel engineering. In this study, systematic study on the pressure arch was presented to predict tunnel collapse. Multiple factors under different conditions were considered. First, the pressure arch was described as a certain scope in comparison with the […]
Mathematical Model of Homogeneous Corrosion of Steel Pipe Pile Foundation for Offshore Wind Turbines and Corrosive Action
sfakianakisdiseasesστοHuman Diseases Medicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 35 δευτερόλεπτα
In this paper, the nonlinear corrosion model under the combined action of the anticorrosion system and corrosive environment is chosen as the mathematical model of homogeneous corrosion of steel pipe pile foundation for the offshore wind turbine. Based on the mathematical model, a three-dimensional finite element model was established for the steel pipe pile foundation […]
Innovations in Glaucoma Surgery: Improving the Results
sfakianakisdiseasesστοHuman Diseases Medicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 35 δευτερόλεπτα
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Niosome Encapsulation of Curcumin: Characterization and Cytotoxic Effect on Ovarian Cancer Cells
sfakianakisdiseasesστοHuman Diseases Medicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 35 δευτερόλεπτα
Curcumin, a natural chemical compound found in Curcuma longa, has been applied in multiple medicinal areas from antibiotic to antitumor treatment. However, the chemical structure of curcumin results in poor stability, low solubility, and rapid degradation in vivo, hindering its clinical utilization. To address these issues, we have developed a novel niosome system composed of […]
Clinical Outcomes and Complications of Cortical Button Distal Biceps Repair: A Systematic Review of the Literature
sfakianakisdiseasesστοHuman Diseases Medicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 35 δευτερόλεπτα
Objectives. The purpose of the present study was to investigate the clinical outcomes and complications of the cortical button distal biceps fixation method. Material and Methods. All methods followed the PRISMA guidelines. Included studies had to describe clinical outcomes and complications after acute distal biceps repair with cortical button fixation. Eligibility criteria also included English […]
Influenza Virus Induces Inflammatory Response in Mouse Primary Cortical Neurons with Limited Viral Replication
sfakianakisdiseasesστοHuman Diseases Medicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 35 δευτερόλεπτα
Unlike stereotypical neurotropic viruses, influenza A viruses have been detected in the brain tissues of human and animal models. To investigate the interaction between neurons and influenza A viruses, mouse cortical neurons were isolated, infected with human H1N1 influenza virus, and then examined for the production of various inflammatory molecules involved in immune response. We […]
Acute Lower Leg Compartment Syndrome: A Rare Complication following CABG
sfakianakisdiseasesστοHuman Diseases Medicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 35 δευτερόλεπτα
Compartment syndrome of lower legs following coronary artery bypass grafting is a rare complication which results from a combination of local and systemic factors. Early recognition is vital for good outcome. The case discussed describes this rare complication of CABG resulting in long term disability. from #AlexandrosSfakianakis via Alexandros G.Sfakianakis on Inoreader http://ift.tt/2absa8t via IFTTT
‘Cytology-on-a-chip’ based sensors for monitoring of potentially malignant oral lesions
otolaryngologistsfakianakisστοOtoRhinoLaryngology by Sfakianakis G.Alexandros,,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,tel : 00302841026182,00306932607174Πριν από 36 δευτερόλεπτα
‘Cytology-on-a-chip’ based sensors for monitoring of potentially malignant oral lesions: It is estimated that 1–2% of adults in the United States present with a worrisome white or red patch or other potentially malignant oral lesion (PMOL) during a routine oral examination [1]. However, the vast majority of these lesions are benign, and only 1–2% will […]
Transoral robotic surgery: The radiation oncologist’s perspective
otolaryngologistsfakianakisστοOtoRhinoLaryngology by Sfakianakis G.Alexandros,,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,tel : 00302841026182,00306932607174Πριν από 36 δευτερόλεπτα
Transoral robotic surgery: The radiation oncologist’s perspective: Surgery has been the cornerstone in the curative management of head and neck cancer for centuries [1]. Over the past 40years, however, non-operative management has become the most common therapy for cancers of the larynx and pharynx due to advances in radiotherapy technique and the significant functional deficits […]
The Management of Locally Invasive Primary Thyroid Paraganglioma
otolaryngologistsfakianakisστοOtoRhinoLaryngology by Sfakianakis G.Alexandros,,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,tel : 00302841026182,00306932607174Πριν από 36 δευτερόλεπτα
The Ma A Case Report and Review of the Literature: Abstract Paragangliomas (PG) are very rare neuroendocrine tumours, arising from neural crest derived paraganglia of the autonomic nervous system. Primary thyroid paraganglioma (PTPG) is a rare site of PG and only 45 cases have been previously reported. The preoperative diagnosis of PTPGs presents a challenge […]
Surgeon specialization and operative mortality in United States: retrospective analysis
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Compliance with birth dose of Hepatitis B vaccine in high endemic and hard to reach areas in the Colombian amazon: results from a vaccination survey
Abstract Background Hepatitis B vaccination was introduced into the Expanded Program of Immunization in Colombia in 1992, in response to WHO recommendations on hepatitis B immunization. Colombia is a low endemic country for Hepatitis B virus infection (HBV) but it has several high endemic areas like the Amazon basin where more than 70 % of… Continue reading Compliance with birth dose of Hepatitis B vaccine in high endemic and hard to reach areas in the Colombian amazon: results from a vaccination survey
Availability and utilization of medical devices in Jimma zone hospitals, Southwest Ethiopia: a case study
Abstract Background Health systems throughout the world, whether in developed or developing countries, are struggling with the challenge of how to manage health-care delivery in conditions of resource constraint. The availability and utilization of various health care equipments at all levels of the health care system has been emphasized for effective and efficient service delivery.… Continue reading Availability and utilization of medical devices in Jimma zone hospitals, Southwest Ethiopia: a case study
Integrative approaches to treating pain
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Pain rehabilitation
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Using Non-Traditional Interfaces to Support Physical Therapy for Knee Strengthening
Abstract Physical therapy consists mainly in the execution of rehabilitation processes that aim to help overcome injuries, as well as develop, maintain, or restore maximum body movement. Knee rehabilitation is one kind of physical therapy that requires daily exercises which could be considered monotonous and boring by the patients, discouraging their improvement. This is coupled… Continue reading Using Non-Traditional Interfaces to Support Physical Therapy for Knee Strengthening
Naturalistic Enactment to Elicit and Recognize Caregiver State Anxiety
Abstract Caring for people with dementia imposes significant stress on family members and caregivers. Often, these informal caregivers have no coping strategy to deal with these behaviors. Anxiety and stress episodes are often triggered by problematic behaviors exhibited by the person who suffers from dementia. Detecting these behaviors could help them in dealing with them… Continue reading Naturalistic Enactment to Elicit and Recognize Caregiver State Anxiety
Implementation and Validation of PACS Integrated Peer Review for Discrepancy Recording of Radiology Reporting
Abstract The purpose of this work is to demonstrate the possibility of implementation of a PACS-integrated peer review system based on RADPEER™ classification providing a step-wise implementation plan utilizing features already present in the standard PACS implementation and without the requirement of additional software development. Furthermore, we show the usage and effects of the system… Continue reading Implementation and Validation of PACS Integrated Peer Review for Discrepancy Recording of Radiology Reporting
Proopiomelanocortin Deficiency Treated with a Melanocortin-4 Receptor Agonist
Melanocyte-stimulating hormone, which is produced from proopiomelanocortin, plays a pivotal role in the regulation of satiety and energy expenditure. In the hypothalamic leptin–melanocortin signaling pathway, melanocyte-stimulating hormone transmits the anorexic effect of leptin through the… from #Medicine-Sfakianakis via simeraentaxei on Inoreader http://ift.tt/2aiBvMM via IFTTT
HIV Infection Linked to Injection Use of Oxymorphone in Indiana, 2014–2015
The epidemic of prescription opioid analgesic use and abuse in the United States over the past two decades has led to a marked increase in the incidence of death from opioid analgesic poisoning, with a quadrupling of the incidence from 1999 through 2011. In 2009, for the first time, deaths from… from #Medicine-Sfakianakis via simeraentaxei… Continue reading HIV Infection Linked to Injection Use of Oxymorphone in Indiana, 2014–2015
Erratum to: Prevalence and factors related to smoking and smoking cessation 6 months following a cancer diagnosis: a population-based study
from Cancer via xlomafota13 on Inoreader http://ift.tt/2abgum4 via IFTTT http://ift.tt/2ad7Sgu from #Med Blogs by Alexandros G.Sfakianakis via Alexandros G.Sfakianakis on Inoreader http://ift.tt/2a2nfGl via IFTTT
Association between CD14 SNP -159 C/T and gastric cancer: an independent case–control study and an updated meta-analysis
[image: 88x31.png] from Cancer via xlomafota13 on Inoreader http://ift.tt/2a1bxfU via IFTTT http://ift.tt/2aaODRU from #Med Blogs by Alexandros G.Sfakianakis via Alexandros G.Sfakianakis on Inoreader http://ift.tt/29WOPBh via IFTTT
Evaluation of MMP-9 and MMP-2 and their suppressor TIMP-1 and TIMP-2 in adenocarcinoma of esophagogastric junction
[image: 88x31.png] from Cancer via xlomafota13 on Inoreader http://ift.tt/2a1bdhd via IFTTT http://ift.tt/2aaOQEw from #Med Blogs by Alexandros G.Sfakianakis via Alexandros G.Sfakianakis on Inoreader http://ift.tt/2a2ngdn via IFTTT
Endocannabinoid system as a regulator of tumor cell malignancy – biological pathways and clinical significance
[image: 88x31.png] from Cancer via xlomafota13 on Inoreader http://ift.tt/29XV9cj via IFTTT http://ift.tt/2ad7sXj from #Med Blogs by Alexandros G.Sfakianakis via Alexandros G.Sfakianakis on Inoreader http://ift.tt/29WPum6 via IFTTT
Case 22-2016: A 65-Year-Old Man with Syncope, Dyspnea, and Leg Edema
Presentation of Case. Dr. David K. Rhee (Cardiology): A 65-year-old man was admitted to this hospital because of syncope, dyspnea, and leg edema. The patient had been in his usual health until approximately 1 month before admission, when cough occurred. One week later, his legs became swollen and… from Cases via ola Kala on Inoreader http://ift.tt/2a158l3 via IFTTT http://ift.tt/2aeqjOG from #Med Blogs by Alexandros G.Sfakianakis via Alexandros G.Sfakianakis on Inoreader http://ift.tt/2a2mRHP via IFTTT
Randomized trial comparing efficacies of zoledronate and alendronate for improving bone mineral density and inhibiting bone remodelling in women with post-menopausal osteoporosis
Summary What is known and objective Bisphosphonates are the first-line medications for treating osteoporosis. The aim of our prospective study was to compare the efficacy of zoledronate with that of alendronate in women with post-menopausal osteoporosis based on the evaluations of bone mineral density (BMD) and serum levels of biochemical markers of bone remodelling. Methods Chinese women with post-menopausal osteoporosis were randomly assigned to the zoledronate (*n* = 52) or alendronate (*n* = 53) group, and were treated with 5 mg zoledronate intravenously once per year and 70 ... περισσότερα »
Nerve growth factor: role in growth, differentiation and controlling cancer cell development
Abstract Recent progress in the Nerve Growth Factor (NGF) research has shown that this factor acts not only outside its classical domain of the peripheral and central nervous system, but also on non-neuronal and cancer cells. This latter observation has led to divergent hypothesis about the role of NGF, its specific distribution pattern within the tissues and its implication in induction as well as progression of carcinogenesis. Moreover, other recent studies have shown that NGF has direct clinical relevance in certain human brain neuron degeneration and a number of human ocular di... περισσότερα »
Safety of interferon-free therapies for chronic hepatitis C: a network meta-analysis
Summary What is known and objective Interferon-free (IFN-free) therapies for hepatitis C virus (HCV) have been developed to provide more effective, tolerable and safer therapeutic strategies. To date, no network meta-analysis (NMA) evaluating the safety profile of these regimens has been performed. This systematic review and NMA aimed to evaluate safety outcomes of IFN-free treatment options for chronic hepatitis C. Methods A systematic review was performed according to PRISMA and Cochrane recommendations. A literature search was conducted in PubMed/Medline, Scopus, Cochrane Lib... περισσότερα »
Natural Convection Coupled with Thermal Radiation in a Square Porous Cavity Having a Heated Plate Inside
Abstract This study reports a numerical simulation of the natural convection combined with thermal radiation in a square porous cavity with a thin isothermally heated plate placed horizontally or vertically at its center. The vertical walls of the cavity are cooled while the horizontal ones are adiabatic. The governing equations were solved using a finite volume method on a uniformly staggered grid system. The computational results are presented in the form of isotherm and streamline plots and Nusselt numbers. The effects of the Darcy number ( \(10^{-5} \le \mathrm{Da} \le ~10^{-2}... περισσότερα »
Drug utilisation in medical intensive care unit: a retrospective analysis from a tertiary care teaching hospital
AlexAndros SfakianakisστοMedicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026Πριν από 46 δευτερόλεπτα
2016-07-21T02-54-44Z *Source:* International Journal of Basic & Clinical Pharmacology Arathy R, Jiyo Chacko, Santosh Pillai, Anish Bhanu, Ruby Raphael, Jalajakumari M. Background: The World Health Organisation has defined drug utilization study as the marketing, distribution, prescription and use of drugs in a society, with special emphasis on the resulting medical, social, and economic consequences. The objective was to evaluate drug utilization pattern in medical intensive care unit (MICU) in a tertiary care teaching hospital. Methods: A retrospective observational study was condu... περισσότερα »
Comparison of cardiovascular safety of escitalopram and sertraline based on electrocardiographic alterations: a pharmacovigilance study
AlexAndros SfakianakisστοMedicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026Πριν από 46 δευτερόλεπτα
2016-07-21T02-54-44Z *Source:* International Journal of Basic & Clinical Pharmacology Balwant K. Choure, Girish T. Raparti, Jayprakash B. Ramanand, Jyoti B. Tapase, Praveenkumar T. Patil, Nitin N. Puram, Rama R. Bhosale. Background: Escitalopram and sertraline are the most commonly prescribed antidepressant drugs, belongs to SSRI class. Both the drugs are long been considered as free from cardiovascular adverse effects. Recently number of studies reported potential association between these drugs and pronounced cardiovascular adverse effects. ECG changes like prolongation of QT inte... περισσότερα »
Prospective study of blood lipid parameters in patients with type-2 diabetes mellitus and its correlation with the glycated hemoglobin
AlexAndros SfakianakisστοMedicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026Πριν από 46 δευτερόλεπτα
2016-07-21T02-49-55Z *Source:* International Journal of Advances in Medicine Kumar Prafull Chandra, Dhirendra Kumar Shukla. Background: Patients with type 2 diabetes mellitus (T2DM) are accompanied (many a time ignored) by dyslipidemia; such patients are the easy targets for the development of cardiovascular disease (CVD). An early treatment to normalize abnormal lipid levels can reduce the CVD and related mortality. The aim was to measure blood lipid parameters in patients with T2DM and their relation with the glycemic control. Methods: Prospective study including 124 T2DM patients... περισσότερα »
Mysterious Myofibroblast: A Cell with Diverse Origin and Multiple Functions
AlexAndros SfakianakisστοMedicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026Πριν από 46 δευτερόλεπτα
2016-07-21T02-41-17Z *Source:* Journal of Interdisciplinary Histopathology Sowmya Rao, Jagadish Rao, Jyothi B.M, Varsha V.K. Myofibroblasts are one of the most controversial cells in recent times. Ever since its first discovery, numerous discussions have been done on its illusive nature and functions. They are commonly considered as smooth muscle like fibroblasts. Their presence and distribution in normal and pathological conditions are still not clear since they are difficult to identify with the routine histological techniques. Recent studies have shown their ubiquitous presence i... περισσότερα »
Effects of oral carbohydrate with amino acid solution on the metabolic status of patients in the preoperative period: a randomized, prospective clinical trial
AlexAndros SfakianakisστοMedicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026Πριν από 46 δευτερόλεπτα
Abstract Objective Enhanced recovery after surgery is increasingly desired nowadays, and preoperative nutrient intake may be beneficial for this purpose. In this study, we investigated whether the intake of preoperative carbohydrate with amino acid (ONS) solution can improve starvation status and lipid catabolism before the induction of anesthesia. Methods This randomized, prospective clinical trial included 24 patients who were divided into two groups before surgery under general anesthesia: a control group, comprising patients who fasted after their last meal the day before sur... περισσότερα »
Progressive impairment of cerebellar mGluR signalling and its therapeutic potential for cerebellar ataxia in spinocerebellar ataxia type 1 model mice
Abstract Spinocerebellar ataxia type 1 (SCA1) is a progressive neurodegenerative disease that presents with cerebellar ataxia and motor learning defects. Previous studies have indicated that the pathology of SCA1, as well as other ataxic diseases, is related to signalling pathways mediated by the metabotropic glutamate receptor type 1 (mGluR1), which is indispensable for proper motor coordination and learning. However, the functional contribution of mGluR signalling to SCA1 pathology is unclear. In the present study, we show that SCA1 model mice develop a functional impairment of m... περισσότερα »
Risk factors, clinical presentation and prognosis of mixed candidaemia: a population-based surveillance in Spain
Summary The low incidence of mixed candidaemia (MC) may have precluded a better knowledge of its clinical presentation. The aim of the study was to analyse the risk factors, clinical presentation and prognosis of MC episodes. A comparison between MC and monomicrobial candidaemia within a prospective programme on candidaemia was performed in 29 hospitals between April 2010 and May 2011. In fifteen episodes of candidaemia corresponding to 15 patients, out of 752, two species of *Candida* (1.9%) were isolated. MC was more frequent in patients with HIV infection (12%, *P* = 0.038) and ... περισσότερα »
Synthesis of Figure-of-Eight Helical BisBODIPY Macrocycles and Their Chiroptical Properties
[image: CrossMark.jpg] *Chem. Commun.*, 2016, Accepted Manuscript *DOI*: 10.1039/C6CC05439K, Communication Makoto Saikawa, Takashi Nakamura, Junji Uchida, Masaki Yamamura, Tatsuya Nabeshima A macrocyclic bisBODIPY (bis(boron-dipyrromethene)) complex [*1*B2] with a figure-of-eight helicity was synthesized and successfully resolved. [*1*B2] was proven to be one of the most efficient red-emitting CPL (circularly polarized luminescence)... The content of this RSS Feed (c) The Royal Society of Chemistry from BioChemistry via xlomafota13 on Inoreader http://ift.tt/2awQHlU via IFTTT
Influenza Virus Induces Inflammatory Response in Mouse Primary Cortical Neurons with Limited Viral Replication
Unlike stereotypical neurotropic viruses, influenza A viruses have been detected in the brain tissues of human and animal models. To investigate the interaction between neurons and influenza A viruses, mouse cortical neurons were isolated, infected with human H1N1 influenza virus, and then examined for the production of various inflammatory molecules involved in immune response. We found that replication of the influenza virus in neurons was limited, although early viral transcription was not affected. Virus-induced neuron viability decreased at 6 h postinfection (p.i.) but increa... περισσότερα »
The Roles of System and Organizational Leadership in System-Wide Evidence-Based Intervention Sustainment: A Mixed-Method Study
AlexAndros SfakianakisστοMedicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026Πριν από 1 ώρα
Abstract If evidence-based interventions (EBIs) are not sustained, investments are wasted and public health impact is limited. Leadership has been suggested as a key determinant of implementation and sustainment; however, little empirical work has examined this factor. This mixed-methods study framed using the Exploration, Preparation, Implementation, Sustainment (EPIS) conceptual framework examines leadership in both the outer service system context and inner organizational context in eleven system-wide implementations of the same EBI across two U.S. states and 87 counties. Quant... περισσότερα »
Simple risk factors to predict urgent endoscopy in nonvariceal upper gastrointestinal bleeding pre-endoscopically
AlexAndros SfakianakisστοMedicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026Πριν από 1 ώρα
Medicine from Gastroenterology via xlomafota13 on Inoreader http://ift.tt/29WL0vO via IFTTT
Efficacy and safety of endoscopic balloon dilation for upper gastrointestinal strictures of Crohn's disease
AlexAndros SfakianakisστοMedicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026Πριν από 1 ώρα
Digestive Diseases and Sciences from Gastroenterology via xlomafota13 on Inoreader http://ift.tt/2a2j9yb via IFTTT
Association of visceral fat area with abdominal skeletal muscle distribution in overweight Japanese adults
AlexAndros SfakianakisστοMedicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026Πριν από 1 ώρα
Obesity Research & Clinical Practice from Gastroenterology via xlomafota13 on Inoreader http://ift.tt/29WL3b2 via IFTTT
HCV eradication does not impact gut dysbiosis or systemic inflammation in cirrhotic patients
AlexAndros SfakianakisστοMedicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026Πριν από 1 ώρα
Alimentary Pharmacology and Therapeutics from Gastroenterology via xlomafota13 on Inoreader http://ift.tt/2a2iY5N via IFTTT
Sleeve gastrectomy and anti-reflux procedures
AlexAndros SfakianakisστοMedicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026Πριν από 1 ώρα
Surgical Endoscopy from Gastroenterology via xlomafota13 on Inoreader http://ift.tt/29WKYny via IFTTT
A phase II study of the HSP90 inhibitor AUY922 in chemotherapy refractory advanced pancreatic cancer
AlexAndros SfakianakisστοMedicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026Πριν από 1 ώρα
Cancer Chemotherapy and Pharmacology from Gastroenterology via xlomafota13 on Inoreader http://ift.tt/2a2iTz5 via IFTTT
Association of model for end-stage liver disease score with mortality in emergency general surgery patients
AlexAndros SfakianakisστοMedicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026Πριν από 1 ώρα
JAMA Surgery from Gastroenterology via xlomafota13 on Inoreader http://ift.tt/29WLfHj via IFTTT
Efficacy and safety of linagliptin in type 2 diabetes patients with self-reported hepatic disorders: A retrospective pooled analysis of 17 randomized, double-blind, placebo-controlled clinical trials
AlexAndros SfakianakisστοMedicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026Πριν από 1 ώρα
Journal of Diabetes and its Complications from Gastroenterology via xlomafota13 on Inoreader http://ift.tt/2a2j5OA via IFTTT
Laparoscopic paraesophageal hernia repair is safe in elderly patients
AlexAndros SfakianakisστοMedicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026Πριν από 1 ώρα
Surgical Endoscopy from Gastroenterology via xlomafota13 on Inoreader http://ift.tt/29WLt1b via IFTTT
Pancreatitis and cholecystitis in primary acute symptomatic Epstein-Barr virus infection - Systematic review of the literature
AlexAndros SfakianakisστοMedicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026Πριν από 1 ώρα
Journal of Clinical Virology from Gastroenterology via xlomafota13 on Inoreader http://ift.tt/2a2jssB via IFTTT
Body fat mass distribution and interrupter resistance, fractional exhaled nitric oxide and asthma at school-age
AlexAndros SfakianakisστοMedicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026Πριν από 1 ώρα
The Journal of Allergy and Clinical Immunology from Gastroenterology via xlomafota13 on Inoreader http://ift.tt/29WL1Qv via IFTTT
Hepatitis due to reactivation of HBV in endemic areas among patients with hepatitis C treated with direct-acting antivirals agents
AlexAndros SfakianakisστοMedicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026Πριν από 1 ώρα
Clinical Gastroenterology and Hepatology from Gastroenterology via xlomafota13 on Inoreader http://ift.tt/2a2iHQt via IFTTT
The risk of coronary artery disease and cerebrovascular disease in patients with hepatitis C: A systematic review and meta-analysis
AlexAndros SfakianakisστοMedicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026Πριν από 1 ώρα
International Journal of Cardiology from Gastroenterology via xlomafota13 on Inoreader http://ift.tt/29WLemu via IFTTT
Prevalence and clinical features of opioid-induced constipation in the general population: A French study of 15,000 individuals
AlexAndros SfakianakisστοMedicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026Πριν από 1 ώρα
United European Gastroenterology Journal from Gastroenterology via xlomafota13 on Inoreader http://ift.tt/2a2jgJS via IFTTT
Early neurodevelopmental outcomes of infants with intestinal failure
AlexAndros SfakianakisστοMedicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026Πριν από 1 ώρα
Early Human Development from Gastroenterology via xlomafota13 on Inoreader http://ift.tt/29WL2Uz via IFTTT
Humoral and cellular responses to casein in food protein-induced enterocolitis to cows milk
AlexAndros SfakianakisστοMedicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026Πριν από 1 ώρα
The Journal of Allergy and Clinical Immunology from Gastroenterology via xlomafota13 on Inoreader http://ift.tt/2a2iVqD via IFTTT
Critical role of fatty acid metabolism in ILC2-mediated barrier protection during malnutrition and helminth infection
AlexAndros SfakianakisστοMedicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026Πριν από 1 ώρα
Journal of Experimental Medicine from Gastroenterology via xlomafota13 on Inoreader http://ift.tt/29Qtcmm via IFTTT
Trajectories and predictors of state and trait anxiety in patients receiving chemotherapy for breast and colorectal cancer: Results from a longitudinal study
AlexAndros SfakianakisστοMedicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026Πριν από 1 ώρα
European Journal of Oncology Nursing from Gastroenterology via xlomafota13 on Inoreader http://ift.tt/2abkEu0 via IFTTT
Evaluating the surgeons perception of difficulties of two techniques to perform STARR for obstructed defecation syndrome: A multicenter randomized trial
AlexAndros SfakianakisστοMedicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026Πριν από 1 ώρα
Surgical Innovation from Gastroenterology via xlomafota13 on Inoreader http://ift.tt/29QtCsZ via IFTTT
Environmental factors in the etiology of type 1 diabetes, celiac disease, and narcolepsy
AlexAndros SfakianakisστοMedicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026Πριν από 1 ώρα
Pediatric Diabetes from Gastroenterology via xlomafota13 on Inoreader http://ift.tt/2abjJdo via IFTTT
What is the BMI threshold for open ventral hernia repair?
AlexAndros SfakianakisστοMedicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026Πριν από 1 ώρα
Abstract Background Overweight and obese patients are often asked to lose weight prior to ventral hernia repair (VHR). Improved outcomes are the reasons behind this strategy. Data regarding weight loss targets are scant, and it is not known at what body mass index (BMI) threshold postoperative complications increase. This study aimed to determine the threshold to allow proper patient counseling. Methods All patients who underwent open VHR at our institution between 2002 and 2015 captured in the NSQIP database were included. The primary outcome was defined as any (≥1) of 18 captur... περισσότερα »
Natural Convection Coupled with Thermal Radiation in a Square Porous Cavity Having a Heated Plate Inside
Abstract This study reports a numerical simulation of the natural convection combined with thermal radiation in a square porous cavity with a thin isothermally heated plate placed horizontally or vertically at its center. The vertical walls of the cavity are cooled while the horizontal ones are adiabatic. The governing equations were solved using a finite volume method on a uniformly staggered grid system. The computational results are presented in the form of isotherm and streamline plots and Nusselt numbers. The effects of the Darcy number ( \(10^{-5} \le \mathrm{Da} \le ~10^{-2}... περισσότερα »
Machine learning based methodology to identify cell shape phenotypes associated with microenvironmental cues
[image: S01429612.gif] Publication date: October 2016 *Source:*Biomaterials, Volume 104 Author(s): Desu Chen, Sumona Sarkar, Julián Candia, Stephen J. Florczyk, Subhadip Bodhak, Meghan K. Driscoll, Carl G. Simon, Joy P. Dunkers, Wolfgang Losert Cell morphology has been identified as a potential indicator of stem cell response to biomaterials. However, determination of cell shape phenotype in biomaterials is complicated by heterogeneous cell populations, microenvironment heterogeneity, and multi-parametric definitions of cell morphology. To associate cell morphology with cell-materia... περισσότερα »
Superhydrophobic materials for biomedical applications
[image: S01429612.gif] Publication date: October 2016 *Source:*Biomaterials, Volume 104 Author(s): Eric J. Falde, Stefan T. Yohe, Yolonda L. Colson, Mark W. Grinstaff Superhydrophobic surfaces are actively studied across a wide range of applications and industries, and are now finding increased use in the biomedical arena as substrates to control protein adsorption, cellular interaction, and bacterial growth, as well as platforms for drug delivery devices and for diagnostic tools. The commonality in the design of these materials is to create a stable or metastable air layer at the m... περισσότερα »
In-situ second harmonic generation by cancer cell targeting ZnO nanocrystals to effect photodynamic action in subcellular space
[image: S01429612.gif] Publication date: October 2016 *Source:*Biomaterials, Volume 104 Author(s): Bobo Gu, Artem Pliss, Andrey N. Kuzmin, Alexander Baev, Tymish Y. Ohulchanskyy, Jossana A. Damasco, Ken-Tye Yong, Shuangchun Wen, Paras N. Prasad This paper introduces the concept of in-situ upconversion of deep penetrating near infrared light via second harmonic generation from ZnO nanocrystals delivered into cells to effect photo activated therapies, such as photodynamic therapy, which usually require activation by visible light with limited penetration through biological tissues. We... περισσότερα »
Hypoxia-directed and activated theranostic agent: Imaging and treatment of solid tumor
[image: S01429612.gif] Publication date: October 2016 *Source:*Biomaterials, Volume 104 Author(s): Rajesh Kumar, Eun-Joong Kim, Jiyou Han, Hyunseung Lee, Weon Sup Shin, Hyun Min Kim, Sankarprasad Bhuniya, Jong Seung Kim, Kwan Soo Hong Hypoxia, a distinguished feature of various solid tumors, has been considered as a key marker for tumor progression. Inadequate vasculature and high interstitial pressures result in relatively poor drug delivery to these tumors. Herein, we developed an antitumor theranostic agent, 4, which is activated in hypoxic conditions and can be used for the diagn... περισσότερα »
Machine learning based methodology to identify cell shape phenotypes associated with microenvironmental cues
[image: S01429612.gif] Publication date: October 2016 *Source:*Biomaterials, Volume 104 Author(s): Desu Chen, Sumona Sarkar, Julián Candia, Stephen J. Florczyk, Subhadip Bodhak, Meghan K. Driscoll, Carl G. Simon, Joy P. Dunkers, Wolfgang Losert Cell morphology has been identified as a potential indicator of stem cell response to biomaterials. However, determination of cell shape phenotype in biomaterials is complicated by heterogeneous cell populations, microenvironment heterogeneity, and multi-parametric definitions of cell morphology. To associate cell morphology with cell-materia... περισσότερα »
Hypoxia-directed and activated theranostic agent: Imaging and treatment of solid tumor
[image: S01429612.gif] Publication date: October 2016 *Source:*Biomaterials, Volume 104 Author(s): Rajesh Kumar, Eun-Joong Kim, Jiyou Han, Hyunseung Lee, Weon Sup Shin, Hyun Min Kim, Sankarprasad Bhuniya, Jong Seung Kim, Kwan Soo Hong Hypoxia, a distinguished feature of various solid tumors, has been considered as a key marker for tumor progression. Inadequate vasculature and high interstitial pressures result in relatively poor drug delivery to these tumors. Herein, we developed an antitumor theranostic agent, 4, which is activated in hypoxic conditions and can be used for the diagn... περισσότερα »
Graphene oxide reinforced polyvinyl alcohol/polyethylene glycol blend composites as high-performance dielectric material
Abstract Novel flexible dielectric composites composed of polyvinyl alcohol (PVA), polyethylene glycol (PEG), and graphene oxide (GO) with high dielectric constant and low dielectric loss have been developed using facile and eco-friendly colloidal processing technique. The structure and morphology of the PVA/PEG/GO composites were evaluated using Fourier transform infrared spectroscopy (FTIR), Raman spectroscopy, UV-vis spectroscopy (UV-vis), X-ray diffraction (XRD), scanning electron microscopy (SEM), and atomic force microscopy (AFM). The dielectric behavior of PVA/PEG/GO compos... περισσότερα »
Annonaceous acetogenins nanosuspensions stabilized by PCL–PEG block polymer: significantly improved antitumor efficacy
sfakianakisdiseasesστοHuman Diseases Medicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 1 ώρα
from #AlexandrosSfakianakis via Alexandros G.Sfakianakis on Inoreader http://ift.tt/2awNXFk via IFTTT
Remote magnetic targeting of iron oxide nanoparticles for cardiovascular diagnosis and therapeutic drug delivery: where are we now?
sfakianakisdiseasesστοHuman Diseases Medicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 1 ώρα
from #AlexandrosSfakianakis via Alexandros G.Sfakianakis on Inoreader http://ift.tt/2awO1oC via IFTTT
Effects of oral carbohydrate with amino acid solution on the metabolic status of patients in the preoperative period: a randomized, prospective clinical trial
Abstract Objective Enhanced recovery after surgery is increasingly desired nowadays, and preoperative nutrient intake may be beneficial for this purpose. In this study, we investigated whether the intake of preoperative carbohydrate with amino acid (ONS) solution can improve starvation status and lipid catabolism before the induction of anesthesia. Methods This randomized, prospective clinical trial included 24 patients who were divided into two groups before surgery under general anesthesia: a control group, comprising patients who fasted after their last meal the day before sur... περισσότερα »
Stellenwert der autologen Fetttransplantation in der ästhetischen Chirurgie des Mammakarzinoms
otolaryngologistsfakianakisστοOtoRhinoLaryngology by Sfakianakis G.Alexandros,,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,tel : 00302841026182,00306932607174Πριν από 1 ώρα
Zusammenfassung Die autologe Fetttransplantation gilt als sekundär rekonstruktives Verfahren und hat als Therapieziel eine Verbesserung der Lebensqualität. Beim Lipofilling wird autologes Fett in den Empfängersitus übertragen, um die Weichteilkontur der Empfängerregion zu optimieren. Brustkrebs ist die häufigste Krebserkrankung der Frau. Dank individualisierter Behandlungsmethoden steigen zwar die Heilungsraten, aber immer mehr Frauen müssen viele Jahre mit […]
Open Frontal Sinus Surgery
In this article, the historical context and current application of external frontal sinus procedures are discussed. In particular, the frontal trephine, frontoethmoidectomy, and osteoplastic flap are described. (Source: Otolaryngologic clinics of North America) from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader http://ift.tt/2a2oA00 via IFTTT
Index
Note: Page numbers of article titles are in boldface type. (Source: Otolaryngologic clinics of North America) from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader http://ift.tt/29WQ5nK via IFTTT
Case 22-2016: A 65-Year-Old Man with Syncope, Dyspnea, and Leg Edema
Presentation of Case. Dr. David K. Rhee (Cardiology): A 65-year-old man was admitted to this hospital because of syncope, dyspnea, and leg edema. The patient had been in his usual health until approximately 1 month before admission, when cough occurred. One week later, his legs became swollen and… from #Medicine-Sfakianakis via simeraentaxei on Inoreader http://ift.tt/2a158l3… Continue reading Case 22-2016: A 65-Year-Old Man with Syncope, Dyspnea, and Leg Edema
Contributors
JEAN ANDERSON ELOY, MD, FACS (Source: Otolaryngologic clinics of North America) from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader http://ift.tt/2a2o2aj via IFTTT
Alveolar Bone Graft: Clinical Profile and Risk Factors for Complications in Oral Cleft Patients.
CONCLUSIONS: Patients with cleft lip and palate who were 12 years or older had a greater chance of developing complications after grafting the alveolar bone. Furthermore, particulate alveolar graft from iliac crest had significantly better outcomes. PMID: 27427932 [PubMed – as supplied by publisher] (Source: The Cleft Palate-Craniofacial Journal) from #Medicine-Sfakianakis via simeraentaxei on Inoreader… Continue reading Alveolar Bone Graft: Clinical Profile and Risk Factors for Complications in Oral Cleft Patients.
Anaphylaxis
Title: AnaphylaxisCategory: Diseases and ConditionsCreated: 4/15/2000 12:00:00 AMLast Editorial Review: 7/20/2016 12:00:00 AM (Source: MedicineNet Allergies General) from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader http://ift.tt/29WQbvz via IFTTT
What Really Rigs Up RIG-I
RIG-I (retinoic acid-inducible gene 1) is an archetypal member of the cytoplasmic DEAD-box dsRNA helicase family (RIG-I-like receptors or RLRs), the members of which play essential roles in the innate immune response of the metazoan cell. RIG-I functions as a pattern recognition receptor that detects nonself RNA as a pathogen-associated molecular pattern (PAMP). However, the… Continue reading What Really Rigs Up RIG-I
Comparison of Oxygen Saturation During Impression Taking Before and After Presurgical Orthopedic Therapy in Babies With Cleft Lip and Palate.
CONCLUSION: The SpO2 values were low at the onset of POT in infants with CLP before any intervention. Oxygen saturation levels may decrease particularly during extraoral impression taking in infants with CLP despite the supplemental oxygen. SpO2 measurements were higher during post-POT intraoral and extraoral impression taking when compared with pre-POT measurements. PMID: 27427934 [PubMed… Continue reading Comparison of Oxygen Saturation During Impression Taking Before and After Presurgical Orthopedic Therapy in Babies With Cleft Lip and Palate.
Size of Velopharyngeal Structures After Primary Palatoplasty.
CONCLUSION: The findings of this study confirmed the hypothesis that patients who underwent surgery with the Furlow technique may present with significantly longer velums than patients who underwent surgery with the Langenbeck procedure. Information regarding velopharyngeal morphology was predictive of velopharyngeal dysfunction for speech for 80% of the participants and can be useful in documenting… Continue reading Size of Velopharyngeal Structures After Primary Palatoplasty.
Characterization and function of a cathepsin B in red crayfish (Procambarus clarkii) following lipopolysaccharide challenge
Publication date: September 2016 Source:Fish & Shellfish Immunology, Volume 56 Author(s): Li-Shang Dai, Yu Sun, Yu-Xuan Sun, Bao-Jian Zhu, Chao-Liang Liu Cathepsin B is a lysosomal cysteine protease of the papain-like enzyme family with multiple biological functions. In the present study, a cathepsin B gene (named PcCTSB) was cloned and characterized from the red crayfish,… Continue reading Characterization and function of a cathepsin B in red crayfish (Procambarus clarkii) following lipopolysaccharide challenge
Machine learning based methodology to identify cell shape phenotypes associated with microenvironmental cues
[image: S01429612.gif] Publication date: October 2016 *Source:*Biomaterials, Volume 104 Author(s): Desu Chen, Sumona Sarkar, Julián Candia, Stephen J. Florczyk, Subhadip Bodhak, Meghan K. Driscoll, Carl G. Simon, Joy P. Dunkers, Wolfgang Losert Cell morphology has been identified as a potential indicator of stem cell response to biomaterials. However, determination of cell shape phenotype in biomaterials is complicated by heterogeneous cell populations, microenvironment heterogeneity, and multi-parametric definitions of cell morphology. To associate cell morphology with cell-materia... περισσότερα »
Superhydrophobic materials for biomedical applications
[image: S01429612.gif] Publication date: October 2016 *Source:*Biomaterials, Volume 104 Author(s): Eric J. Falde, Stefan T. Yohe, Yolonda L. Colson, Mark W. Grinstaff Superhydrophobic surfaces are actively studied across a wide range of applications and industries, and are now finding increased use in the biomedical arena as substrates to control protein adsorption, cellular interaction, and bacterial growth, as well as platforms for drug delivery devices and for diagnostic tools. The commonality in the design of these materials is to create a stable or metastable air layer at the m... περισσότερα »
In-situ second harmonic generation by cancer cell targeting ZnO nanocrystals to effect photodynamic action in subcellular space
[image: S01429612.gif] Publication date: October 2016 *Source:*Biomaterials, Volume 104 Author(s): Bobo Gu, Artem Pliss, Andrey N. Kuzmin, Alexander Baev, Tymish Y. Ohulchanskyy, Jossana A. Damasco, Ken-Tye Yong, Shuangchun Wen, Paras N. Prasad This paper introduces the concept of in-situ upconversion of deep penetrating near infrared light via second harmonic generation from ZnO nanocrystals delivered into cells to effect photo activated therapies, such as photodynamic therapy, which usually require activation by visible light with limited penetration through biological tissues. We... περισσότερα »
Hypoxia-directed and activated theranostic agent: Imaging and treatment of solid tumor
[image: S01429612.gif] Publication date: October 2016 *Source:*Biomaterials, Volume 104 Author(s): Rajesh Kumar, Eun-Joong Kim, Jiyou Han, Hyunseung Lee, Weon Sup Shin, Hyun Min Kim, Sankarprasad Bhuniya, Jong Seung Kim, Kwan Soo Hong Hypoxia, a distinguished feature of various solid tumors, has been considered as a key marker for tumor progression. Inadequate vasculature and high interstitial pressures result in relatively poor drug delivery to these tumors. Herein, we developed an antitumor theranostic agent, 4, which is activated in hypoxic conditions and can be used for the diagn... περισσότερα »
Machine learning based methodology to identify cell shape phenotypes associated with microenvironmental cues
[image: S01429612.gif] Publication date: October 2016 *Source:*Biomaterials, Volume 104 Author(s): Desu Chen, Sumona Sarkar, Julián Candia, Stephen J. Florczyk, Subhadip Bodhak, Meghan K. Driscoll, Carl G. Simon, Joy P. Dunkers, Wolfgang Losert Cell morphology has been identified as a potential indicator of stem cell response to biomaterials. However, determination of cell shape phenotype in biomaterials is complicated by heterogeneous cell populations, microenvironment heterogeneity, and multi-parametric definitions of cell morphology. To associate cell morphology with cell-materia... περισσότερα »
Hypoxia-directed and activated theranostic agent: Imaging and treatment of solid tumor
[image: S01429612.gif] Publication date: October 2016 *Source:*Biomaterials, Volume 104 Author(s): Rajesh Kumar, Eun-Joong Kim, Jiyou Han, Hyunseung Lee, Weon Sup Shin, Hyun Min Kim, Sankarprasad Bhuniya, Jong Seung Kim, Kwan Soo Hong Hypoxia, a distinguished feature of various solid tumors, has been considered as a key marker for tumor progression. Inadequate vasculature and high interstitial pressures result in relatively poor drug delivery to these tumors. Herein, we developed an antitumor theranostic agent, 4, which is activated in hypoxic conditions and can be used for the diagn... περισσότερα »
Graphene oxide reinforced polyvinyl alcohol/polyethylene glycol blend composites as high-performance dielectric material
Abstract Novel flexible dielectric composites composed of polyvinyl alcohol (PVA), polyethylene glycol (PEG), and graphene oxide (GO) with high dielectric constant and low dielectric loss have been developed using facile and eco-friendly colloidal processing technique. The structure and morphology of the PVA/PEG/GO composites were evaluated using Fourier transform infrared spectroscopy (FTIR), Raman spectroscopy, UV-vis spectroscopy (UV-vis), X-ray diffraction (XRD), scanning electron microscopy (SEM), and atomic force microscopy (AFM). The dielectric behavior of PVA/PEG/GO compos... περισσότερα »
Fugitive emissions from nanopowder manufacturing
Abstract In response to health and safety questions and concerns regarding particulate matter emissions from equipment used for synthesizing NiFe and TiO2 nanopowders, a study was undertaken to assess their impact on the air quality inside and outside a laboratory where the manufacturing equipment is operated. Elemental concentrations determined by ion beam analysis (IBA) of air particulate matter (PM) samples collected hourly with a StreakerTM sampler were used to identify possible sources and estimate contributions from nanopowder production and other sources. The fugitive nanopo... περισσότερα »
Tamoxifen metabolite endoxifen interferes with the polyamine pathway in breast cancer
Abstract Tamoxifen is the most widely used drug to treat women with estrogen receptor α (ERα)-positive breast cancer. Endoxifen is recognized as the active metabolite of tamoxifen in humans. We studied endoxifen effects on ERα-positive MCF-7 breast cancer cells. Estradiol increased the proliferation of MCF-7 cells by two- to threefold and endoxifen suppressed its effects. Endoxifen suppressed *c*-*myc*, *c*-*fos* and *Tff1* oncogene expression, as revealed by RT-PCR. Estradiol increased the activity of ornithine decarboxylase (ODC) and adenosyl methioninedecarboxylase (AdoMetDC), ... περισσότερα »
Gyroscopic behavior exhibited by the optical Kerr effect in bimetallic Au–Pt nanoparticles suspended in ethanol
Abstract The modification in the third-order nonlinear optical response exhibited by rotating bimetallic Au–Pt nanoparticles in an ethanol solution was analyzed. The samples were prepared by a sol–gel processing route. The anisotropy associated to the elemental composition of the nanoparticles was confirmed by high-resolution transmission electron microscopy and energy-dispersive X-ray spectroscopy measurements. The size of the nanoparticles varies in the range from 9 to 13 nm, with an average size of 11 nm. Changes in the spatial orientation of the nanomaterials automatically gen... περισσότερα »
A photochemical approach to aromatic extension of the corannulene nucleus
[image: GA?id=C6CC04910A] *Chem. Commun.*, 2016, Advance Article *DOI*: 10.1039/C6CC04910A, Communication Venkatachalam Rajeshkumar, Mihaiela C. Stuparu Conjugated aromatic units of choice can be fused to corannulene in an efficient manner through a photo-induced oxidative cyclization process. To cite this article before page numbers are assigned, use the DOI form of citation above. The content of this RSS Feed (c) The Royal Society of Chemistry [image: 2aiDFfm] from BioChemistry via xlomafota13 on Inoreader http://ift.tt/2a1ddpB via IFTTT from #Med Blogs by Alexandros G.Sfakianakis ... περισσότερα »
Pembrolizumab-Induced Demyelinating Polyradiculoneuropathy
To the Editor: Pembrolizumab and nivolumab, two humanized antibodies against programmed cell death 1 (PD-1) receptor, were recently approved for the treatment of unresectable or metastatic melanoma and for other cancers. We report two cases of severe demyelinating polyradiculoneuropathy that… from Melanoma via xlomafota13 on Inoreader http://ift.tt/2aejix9 from #Med Blogs by Alexandros G.Sfakianakis via Alexandros G.Sfakianakis on Inoreader http://ift.tt/29QtZnl via IFTTT from #Med Blogs by Alexandros G.Sfakianakis via Alexandros G.Sfakianakis on Inoreader http://ift.tt/2aeucTM ... περισσότερα »
Pembrolizumab-Induced Demyelinating Polyradiculoneuropathy
[image: nejmc1515584_f1.gif] To the Editor: Pembrolizumab and nivolumab, two humanized antibodies against programmed cell death 1 (PD-1) receptor, were recently approved for the treatment of unresectable or metastatic melanoma and for other cancers. We report two cases of severe demyelinating polyradiculoneuropathy that… from Melanoma via xlomafota13 on Inoreader http://ift.tt/2aejix9 from #Med Blogs by Alexandros G.Sfakianakis via Alexandros G.Sfakianakis on Inoreader http://ift.tt/2abklja via IFTTT from #Med Blogs by Alexandros G.Sfakianakis via Alexandros G.Sfakianakis on Inor... περισσότερα »
What is the BMI threshold for open ventral hernia repair?
Abstract Background Overweight and obese patients are often asked to lose weight prior to ventral hernia repair (VHR). Improved outcomes are the reasons behind this strategy. Data regarding weight loss targets are scant, and it is not known at what body mass index (BMI) threshold postoperative complications increase. This study aimed to determine the threshold to allow proper patient counseling. Methods All patients who underwent open VHR at our institution between 2002 and 2015 captured in the NSQIP database were included. The primary outcome was defined as any (≥1) of 18 captur... περισσότερα »
Case 22-2016: A 65-Year-Old Man with Syncope, Dyspnea, and Leg Edema
Presentation of Case. Dr. David K. Rhee (Cardiology): A 65-year-old man was admitted to this hospital because of syncope, dyspnea, and leg edema. The patient had been in his usual health until approximately 1 month before admission, when cough occurred. One week later, his legs became swollen and… from Cases via ola Kala on Inoreader http://ift.tt/2a158l3 via IFTTT from #Med Blogs by Alexandros G.Sfakianakis via Alexandros G.Sfakianakis on Inoreader http://ift.tt/2aeqjOG via IFTTT from #Med Blogs by Alexandros G.Sfakianakis via Alexandros G.Sfakianakis on Inoreader http://ift.tt/... περισσότερα »
Simple risk factors to predict urgent endoscopy in nonvariceal upper gastrointestinal bleeding pre-endoscopically
Medicine from Gastroenterology via xlomafota13 on Inoreader http://ift.tt/29WL0vO via IFTTT from #Med Blogs by Alexandros G.Sfakianakis via Alexandros G.Sfakianakis on Inoreader http://ift.tt/2aetm9B via IFTTT
Efficacy and safety of endoscopic balloon dilation for upper gastrointestinal strictures of Crohn's disease
Digestive Diseases and Sciences from Gastroenterology via xlomafota13 on Inoreader http://ift.tt/2a2j9yb via IFTTT from #Med Blogs by Alexandros G.Sfakianakis via Alexandros G.Sfakianakis on Inoreader http://ift.tt/29XzFii via IFTTT
Association of visceral fat area with abdominal skeletal muscle distribution in overweight Japanese adults
Obesity Research & Clinical Practice from Gastroenterology via xlomafota13 on Inoreader http://ift.tt/29WL3b2 via IFTTT from #Med Blogs by Alexandros G.Sfakianakis via Alexandros G.Sfakianakis on Inoreader http://ift.tt/2awLwT7 via IFTTT
Sleeve gastrectomy and anti-reflux procedures
Abstract Background Obesity is an epidemic in the USA that continues to grow, becoming a leading cause of premature avoidable death. Bariatric surgery has become an effective solution for obesity and its comorbidities, and one of the most commonly utilized procedures, the sleeve gastrectomy, can lead to an increase in gastroesophageal reflux following the operation. While these data are controversial, sometimes operative intervention can be necessary to provide durable relief for this problem. Methods We performed an extensive literature review examining the different methods of ... περισσότερα »
HCV eradication does not impact gut dysbiosis or systemic inflammation in cirrhotic patients
Alimentary Pharmacology and Therapeutics from Gastroenterology via xlomafota13 on Inoreader http://ift.tt/2a2iY5N via IFTTT from #Med Blogs by Alexandros G.Sfakianakis via Alexandros G.Sfakianakis on Inoreader http://ift.tt/2awLJWC via IFTTT
Pembrolizumab-Induced Demyelinating Polyradiculoneuropathy
To the Editor: Pembrolizumab and nivolumab, two humanized antibodies against programmed cell death 1 (PD-1) receptor, were recently approved for the treatment of unresectable or metastatic melanoma and for other cancers. We report two cases of severe demyelinating polyradiculoneuropathy that… from Melanoma via xlomafota13 on Inoreader http://ift.tt/2aejix9 from #Med Blogs by Alexandros G.Sfakianakis via Alexandros G.Sfakianakis on Inoreader http://ift.tt/29QtZnl via IFTTT
Pembrolizumab-Induced Demyelinating Polyradiculoneuropathy
[image: nejmc1515584_f1.gif] To the Editor: Pembrolizumab and nivolumab, two humanized antibodies against programmed cell death 1 (PD-1) receptor, were recently approved for the treatment of unresectable or metastatic melanoma and for other cancers. We report two cases of severe demyelinating polyradiculoneuropathy that… from Melanoma via xlomafota13 on Inoreader http://ift.tt/2aejix9 from #Med Blogs by Alexandros G.Sfakianakis via Alexandros G.Sfakianakis on Inoreader http://ift.tt/2abklja via IFTTT
What is the BMI threshold for open ventral hernia repair?
Abstract Background Overweight and obese patients are often asked to lose weight prior to ventral hernia repair (VHR). Improved outcomes are the reasons behind this strategy. Data regarding weight loss targets are scant, and it is not known at what body mass index (BMI) threshold postoperative complications increase. This study aimed to determine the threshold to allow proper patient counseling. Methods All patients who underwent open VHR at our institution between 2002 and 2015 captured in the NSQIP database were included. The primary outcome was defined as any (≥1) of 18 captur... περισσότερα »
Case 22-2016: A 65-Year-Old Man with Syncope, Dyspnea, and Leg Edema
Presentation of Case. Dr. David K. Rhee (Cardiology): A 65-year-old man was admitted to this hospital because of syncope, dyspnea, and leg edema. The patient had been in his usual health until approximately 1 month before admission, when cough occurred. One week later, his legs became swollen and… from Cases via ola Kala on Inoreader http://ift.tt/2a158l3 via IFTTT from #Med Blogs by Alexandros G.Sfakianakis via Alexandros G.Sfakianakis on Inoreader http://ift.tt/2aeqjOG via IFTTT
Sleeve gastrectomy and anti-reflux procedures
Abstract Background Obesity is an epidemic in the USA that continues to grow, becoming a leading cause of premature avoidable death. Bariatric surgery has become an effective solution for obesity and its comorbidities, and one of the most commonly utilized procedures, the sleeve gastrectomy, can lead to an increase in gastroesophageal reflux following the operation. While these data are controversial, sometimes operative intervention can be necessary to provide durable relief for this problem. Methods We performed an extensive literature review examining the different methods of ... περισσότερα »
Phytostabilization potential of two ecotypes of Vetiveria zizanioides in cadmium-contaminated soils: greenhouse and field experiments
sfakianakisdiseasesστοHuman Diseases Medicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 1 ώρα
Abstract Soil contamination by cadmium (Cd) poses a serious environmental and public health concern. Phytoremediation, i.e., the use of plants to remove contaminants from soil, has been proposed for treatment of Cd-contaminated ecosystems. In this study, we demonstrated the potential of Vetiveria zizanioides, commonly known as vetiver, to serve as an effective phytoremediation agent. Two […]
Simultaneous arsenite oxidation and nitrate reduction at the electrodes of bioelectrochemical systems
sfakianakisdiseasesστοHuman Diseases Medicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 1 ώρα
Abstract Arsenic and nitrate contaminations in the soil and groundwater have urged the scientific community to explore suitable technologies for treatment of both contaminants. This study reports, for the first time, a novel application of bioelectrochemical systems for coupling As detoxification at the anode and denitrification at the cathode. A similar As(III) oxidation efficiency was […]
Anthropogenic disturbances influencing ciliate functional feeding groups in impacted tropical streams
sfakianakisdiseasesστοHuman Diseases Medicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 1 ώρα
Abstract Anthropogenic disturbances change the trophic structure of streams, ultimately affecting ecosystem functioning. We investigated the effects of human disturbances, mainly organic pollution, on ciliate functional feeding groups (FFG) in 10 tropical streams near agricultural and urban habitats, in the dry and rainy seasons. We hypothesised that the organic pollution would affect the ciliate composition […]
Effects of honey HMF on enzyme activities and serum biochemical parameters of Wistar rats
sfakianakisdiseasesστοHuman Diseases Medicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 1 ώρα
Abstract Hydroxymethylfurfural (HMF) is a by-product of thermal degradation of glucose and fructose. In this study, the effects of high HMF content of honey on biochemical parameters of rats were investigated. Experiments were conducted with 40 Wistar albino male rats, each weighing 250–350 g and covered a period of 5 weeks. The animals were divided […]
Should people who are not terminally ill have the right to die?
sfakianakisdiseasesστοHuman Diseases Medicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 1 ώρα
The debate around extending assisted suicide to people who experience unbearable mental suffering, rather than physical suffering, is an ethical minefield from #AlexandrosSfakianakis via Alexandros G.Sfakianakis on Inoreader http://ift.tt/29TXC8T via IFTTT
CT myocardial perfusion imaging evolves
sfakianakisdiseasesστοHuman Diseases Medicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 1 ώρα
As researchers gain experience with CT myocardial perfusion imaging (MPI),… Read more on AuntMinnieEurope.com Related Reading: Very low calcium scores do not guarantee negative MPI Cardiac MRI beats SPECT for predicting heart events CCTA falls short in detecting culprit plaque CCTA halves adverse events in SCOT-HEART trial from #AlexandrosSfakianakis via Alexandros G.Sfakianakis on Inoreader http://ift.tt/2aaLt0p […]
Sinonasal Inflammatory Myofibroblastic Tumor with Anaplastic Lymphoma Kinase 1 Rearrangement: Case Study and Literature Review
sfakianakisdiseasesστοHuman Diseases Medicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 1 ώρα
Abstract Inflammatory myofibroblastic tumors (IMTs) are rare mesenchymal tumors initially described in the lung. About half of them exhibit expression of the ALK1 protein, generally resulting from a gene rearrangement. Paranasal sinus IMTs are extremely uncommon, and gene rearrangement of ALK1 is very rare in this localization. A 47-year-old woman presented with rapidly progressive vision […]
A phase I trial of cabozantinib and gemcitabine in advanced pancreatic cancer
sfakianakisdiseasesστοHuman Diseases Medicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 1 ώρα
Summary Background Cabozantinib and gemcitabine improve tumor control in pancreatic ductal adenocarcinoma (PDAC) in preclinical models through c-Met inhibition. We sought to determine the maximum tolerated dose (MTD) of this combination in patients with advanced PDAC. Methods Patients with ≤1 prior treatment and adequate performance status were eligible. Cabozantinib was given orally once daily, beginning […]
Endpoints for therapeutic interventions in faecal incontinence: small step or game changer
Abstract Faecal incontinence (FI) is common and its pathophysiology and treatments continue to evolve. However, a standard measure(s) for assessing its clinical outcome has been elusive. Consequently, over 100 measures and scoring systems, each with intrinsic biases have been reported. These include adequate relief or global satisfaction, ≥50% reduction in episodes or days without FI, quality of life (QOL), FI severity scales and composite indices. Earlier scales relied on the frequency and type of solid, liquid or flatus incontinence and effects on life style whereas newer scales ... περισσότερα »
The brain is not empty: Central mechanisms of nausea and vomiting
from Swallowing and Swallowing Disorders (Dysphagia) via xlomafota13 on Inoreader http://ift.tt/29Qgu7f via IFTTT
Sinonasal Inflammatory Myofibroblastic Tumor with Anaplastic Lymphoma Kinase 1 Rearrangement: Case Study and Literature Review
otolaryngologistsfakianakisστοOtoRhinoLaryngology by Sfakianakis G.Alexandros,,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,tel : 00302841026182,00306932607174Πριν από 2 ώρες
Abstract Inflammatory myofibroblastic tumors (IMTs) are rare mesenchymal tumors initially described in the lung. About half of them exhibit expression of the ALK1 protein, generally resulting from a gene rearrangement. Paranasal sinus IMTs are extremely uncommon, and gene rearrangement of ALK1 is very rare in this localization. A 47-year-old woman presented with rapidly progressive vision […]
Effects of oral carbohydrate with amino acid solution on the metabolic status of patients in the preoperative period: a randomized, prospective clinical trial
Abstract Objective Enhanced recovery after surgery is increasingly desired nowadays, and preoperative nutrient intake may be beneficial for this purpose. In this study, we investigated whether the intake of preoperative carbohydrate with amino acid (ONS) solution can improve starvation status and lipid catabolism before the induction of anesthesia. Methods This randomized, prospective clinical trial included 24 patients who were divided into two groups before surgery under general anesthesia: a control group, comprising patients who fasted after their last meal the day before sur... περισσότερα »
Clinicopathologic Characteristics of Solid Papillary Carcinoma of the Breast.
[image: wk-health-logo.gif] Solid papillary carcinoma (SPC) of the breast is defined as a "distinctive form of papillary carcinoma characterized by closely apposed expansive, cellular nodules." This uncommon tumor frequently demonstrates neuroendocrine differentiation. SPCs are staged as in situ tumors, except those that exhibit jagged borders within desmoplastic stroma, or if accompanied by conventional invasive carcinoma, which is separately graded and staged. In this study, we review the immunomorphologic characteristics of SPCs diagnosed at our institution, with a view toward e... περισσότερα »
A Histomorphologic Grading System That Predicts Overall Survival in Diffuse Malignant Peritoneal Mesothelioma With Epithelioid Subtype.
[image: wk-health-logo.gif] Diffuse malignant peritoneal mesothelioma (MPeM) is rare and arises from peritoneal serosal surfaces. Although it shares similar histomorphology with its counterpart, malignant pleural mesothelioma, etiologies, clinical courses, and therapies differ. Nuclear grading and level of mitoses have been correlated with prognosis in malignant pleural mesothelioma with epithelioid subtype. Whether nuclear grading and level of mitoses correlate with prognosis in MPeM is still unknown. Our study utilizes a 2 tier system incorporating nuclear features and level of t... περισσότερα »
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