Granulocyte transfusions in patients with chronic granulomatous disease and refractory infections: the NIH experience

Publication date: Available online 22 March 2017
Source:Journal of Allergy and Clinical Immunology
Author(s): Beatriz E. Marciano, Elisabeth S. Allen, Cathy C. Cantilena, Ervand Kristosturyan, Harvey G. Klein, Thomas A. Fleisher, Steven M. Holland, Harry L. Malech, Sergio D. Rosenzweig
Granulocyte transfusions are a relatively safe adjunctive therapeutic option for patients with chronic granulomatous disease and severe/refractory bacterial or fungal infections. Early initiation, high frequency and sustained therapy is associated with significantly better outcomes.



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