Nail removal in pachyonychia congenita: Patient-reported survey outcomes

To the Editor: Pachyonychia congenita (PC), a genodermatosis characterized by onychodystrophy and painful palmoplantar keratoderma, is caused by mutations in several keratin genes (KRT6A, KRT6B, KRT6C, KRT16, KRT17). The nail dystrophy may cause pain, infection, and functional and psychosocial impairment.1 Prior studies on nail removal are limited.2,3

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