Clinical and Microstructural Findings in Paget's Disease of the Entire Mandible

Publication date: Available online 20 July 2017
Source:Journal of Oral and Maxillofacial Surgery
Author(s): Reinhard E. Friedrich, Andreas M. Luebke, Michael Amling, Till Koehne
Paget's disease of bone (PDB) is a chronic progressive bone disorder characterized by localized increased bone turnover and focal areas of woven bone formation. Although skull involvement is common, PDB very rarely affects the mandible. This report describes the clinical and histological findings in a 75-year old patient with PDB involving the mandible. Microstructural analyses revealed the altered quality of the bone microstructure and the depletion of the affected bone from calcium. Differential diagnosis of PDB affecting the mandible is discussed.



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