Histamine H2 receptor stimulation up-regulates Th2 chemokine CCL17 production in human M2a macrophages

Publication date: Available online 18 July 2017
Source:Journal of Allergy and Clinical Immunology
Author(s): Susanne Mommert, Karl Gregor, Kristine Rossbach, Katrin Schaper, Torsten Witte, Ralf Gutzmer, Thomas Werfel

Teaser

Stimulation of the histamine H2 receptor significantly increased CCL17 production in human monocyte derived M2a macrophages. These results may be helpful to identify novel therapeutical target structures in diseases driven at least in part by histamine.


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