Discrepancy between clinical and pathological neck staging in oral cavity carcinomas

Publication date: March–April 2018
Source:Acta Otorrinolaringologica (English Edition), Volume 69, Issue 2
Author(s): Vânia Henriques, Eduardo Breda, Eurico Monteiro
IntroductionThe presence of cervical lymph node metastases in patients with oral cavity squamous cell carcinoma reduces survival by up to 50%.ObjectiveThe aims of this study are to assess the accuracy of clinical N staging versus pathological N staging and its impact on survival in order to identify predictive factors associated with the presence of occult neck metastases.MethodsOutcomes of 105 patients with oral cavity squamous cell carcinoma who underwent surgical treatment of the primary tumor and neck were retrospectively evaluated.ResultsFor pN0 and pN+ patients 5-year overall survival was respectively 53% and 27%; disease specific survival was 66% for pN0 and 33% for pN+. Patients with clinical negative lymph nodes were pathologically upstaged in 62% of cases. Disease specific survival according to staging discrepancy had statistically significant impact on survival (p=0.009).ConclusionClinical staging usually underestimates the presence of nodal disease. Neck dissection should be performed in cN0 oral cavity squamous cell carcinoma.



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