Management of anaphylaxis and allergies in patients with long QT syndrome - review of current evidence

Long QT syndrome (LQTS) represents a diverse group of inherited and acquired disorders of ventricular repolarization characterized by prolongation of the QT interval associated with an increased risk of life-threatening Torsades de Pointes (TdP) ventricular tachycardias. Symptoms of TdP ventricular tachycardia range from syncope, when TdP stops spontaneously, to cardiac arrest, when TdP deteriorates to ventricular fibrillation. The diagnosis of inherited LQTS (iLQTS) relies on prolonged QT interval in the electrocardiogram (ECG) or prolongation of the heart beat corrected QT interval (QTc) respectively, clinical and family history and/ or genetic testing 1.

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