Autologous Platelet Rich Fibrin: Can it Secure a Better Healing ?

Publication date: Available online 31 August 2018

Source: Oral Surgery, Oral Medicine, Oral Pathology and Oral Radiology

Author(s): Sheetal Kapse, Sanidhya Surana, M. Satish, Syed Erfan Hussain, Sunil Vyas, Deepak Thakur

Abstract

Objective

To evaluate the efficacy of platelet rich fibrin (PRF) in the healing of impacted mandibular third molar (M3) extraction sockets.

Study Design

This study included 30 patients with bilaterally symmetrical impacted M3 (total n = 60) requiring transalveolar extraction. All patients were randomly provided numbers; left-sided odd numbered M3 patients and right-sided even numbered patients were categorized into group A (test group), while the other side of the mouth was classified as "Group B" (control group). Group A M3 extraction sockets received PRF, while group B sockets were closed without PRF. Patients were evaluated for pain and swelling on post-operative days 1,3,7, and 14. Bone healing was compared on the 8^th and 16^th post-operative weeks. ANOVA and Tukey multiple comparison tests were applied for statistical analysis.

Results

A total of 30 patients between the age of 18 to 40 yearsparticipated in this study. The overall post-operative pain score (VAS) and facial swelling percentages were lower for group A compared to group B (p<0.05). Early bone healing was also evident on the 8^th and 16^th week post-operative radiographs in group A (p < 0.001).

Conclusion

Use of autologous PRF aids in earlier and better wound healing in a controlled manner.

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