Early Detection of Cherubism with Eventual Bilateral Progression: A Literature Review and Case Report

Publication date: Available online 1 September 2018

Source: Oral Surgery, Oral Medicine, Oral Pathology and Oral Radiology

Author(s): Tyler J. Holley, Peter J. Giannini, Nagamani Narayana, Valmont P. Desa

Abstract

Cherubism is a rare familial disease of childhood that commonly affects the bilateral mandible and maxilla and typically resolves in adulthood. It has been shown to have a male predilection and has been mapped to the SH3BP2 gene. Only two cases of unilateral cherubism have been documented in the literature, with the first case eventually affecting the contralateral side. Although rare, unilateral cherubism presents a diagnostic dilemma to the surgeon. This case report describes a unique presentation of unilateral cherubism that progressed to affect the contralateral side and describes some of the considerations for surgeons in the diagnosis and treatment of unilateral benign giant cell lesions of the jaws.

https://ift.tt/2MHoI9L