Isolated gluteal metastasis three years after sufficiently treated oral squamous cell carcinoma: case report and literature review

Publication date: Available online 31 August 2018

Source: Oral Surgery, Oral Medicine, Oral Pathology and Oral Radiology

Author(s): Andreas Naros, Hannes Weise, Michael Krimmel, Siegmar Reinert

Abstract

Metastases from oral squamous cell carcinoma usually occur in the cervical lymph nodes. Distant skeletal muscle metastases are exceedingly rare and have been reported only in sporadic cases.

A 70-year-old male patient was diagnosed with non-metastatic oral SCC (pT4aN0M0). The patient underwent successful surgical treatment involving tumor resection and selective neck dissection of both sides, including adjuvant radiotherapy. After three years of uneventful course, with no clinical or radiographic evidence for local recurrence or metastasis, an isolated distant metastasis in the gluteal muscles was diagnosed. Patient deceased seven months after diagnosis despite further surgical resection and adjuvant chemotherapy.

Distant metastases are mostly accompanied by systemic spread of tumor cells. Thus, the prognosis is generally very poor. The therapeutic concept of surgical tumor resection and adjuvant chemotherapy failed to significant improving the patient's prognosis in the present case.

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