Natural history of untreated squamous cell carcinoma of the head and neck

Abstract

The natural history of untreated head and neck squamous cell carcinoma (SCC) was not well defined.

A total of 206 patients with untreated head and neck SCC were retrospectively enrolled.

The 1‐year survival rate for cancers arising in oral cavity, oropharynx, throat, and hypopharynx was 31%, 20%, 0%, and 3%, respectively, the difference was significant (p<0.001).

57.2% of the patients died within 12 months, median survival time was 11 months.

The prognosis of untreated head and neck SCC patients is extremely unfavorable. T stage is the strongest predictors for the survival time.

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