Biopsy correlation of surface area vs single axis measurements on CT scan of lymph nodes in patients with erythrodermic mycosis fungoides and Sezary syndrome

Abstract

Sezary syndrome (SS) presents with erythroderma, leukaemic blood involvement and frequent lymphadenopathy whilst 15% of mycosis fungoides (MF) patients present with erythroderma¹. Staging of patients with erythrodermic (e)MF/SS includes IIIA, IIIB, IVA or IVB dependant on blood, lymph node (LN) or visceral involvement².

In MF/SS; an abnormal LN is either firm, irregular, clustered, or fixed on examination or ≥15mm on imaging. Excisional biopsy is indicated of the largest, most suspicious node ^{2 −4}.

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