Hyperspectral imaging in detecting dermal invasion in lentigo maligna melanoma

Abstract

Invasive lentigo maligna melanoma (LMM) and its in situ precursor lentigo maligna (LM) are the most common melanoma types on the head and neck areas ¹. Clinically unsuspected invasion is revealed histologically in 5-52% of LMs ². Thus, correct early diagnoses are crucial for determining accurate resection margins and the discussion of sentinel lymph node examination ³.

Hyperspectral imaging is based on the detection of spectral differences reflecting a tissue's biological properties and can be used for detecting skin malignancies ^4,5.

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