Mohs micrographic surgery of rare cutaneous tumors

Abstract

Background

Recurrence rates after Mohs micrographic surgery (MMS) for rare cutaneous tumors are poorly defined.

Objective

Investigate the recurrence rate after MMS for rare cutaneous tumors at a university center.

Methods & Materials

Retrospective review of all rare cutaneous tumors treated with MMS at a large university center between January 2008 and December 2012. To detect all recurrences, patients were linked to The nationwide network and registry of histo- and cytopathology (PALGA).

Results

In total, 80 patients with 80 tumors were included. Tumor types included dermatofibrosarcoma protuberans (27), atypical fibroxanthoma (22), Merkel cell carcinoma (8), microcystic adnexal carcinoma (9), sebaceous carcinoma (6), extramammary Paget's disease (2), and other (6). Mean follow-up time was 3.7 years (standard deviation 1.4) during which two atypical fibroxanthomas recurred (2.5%).

Conclusion

This large case series shows that MMS is an appropriate treatment for rare cutaneous tumors with a recurrence rate less than 3%. Preferably, MMS for rare cutaneous tumors is performed in experienced multidisciplinary centers to further improve the quality of treatment.

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