Αρχειοθήκη ιστολογίου

Αλέξανδρος Γ. Σφακιανάκης
ΩτοΡινοΛαρυγγολόγος
Αναπαύσεως 5
Άγιος Νικόλαος Κρήτη 72100
2841026182
6032607174

Πέμπτη 15 Δεκεμβρίου 2016

Monitoring structural changes in Demodex mites under topical Ivermectin in Rosacea by means of Reflectance confocal microscopy: a case series

Abstract

Rosacea is a common inflammatory disease, mainly affecting the face and with significant impact on patients' life quality. Just recently, topical Ivermectin (Soolantra® 10mg/g Crème) has been introduced in the treatment of rosacea thanks to its double anti-parasitic and anti-inflammatory activity, resulting in a reduction of papulo-pustular manifestations, blepharitis and cutaneous demodicosis.1 Although the role of the human skin commensal Demodex folliculorum (DF) in the pathogenesis of the disease is still debated2, numerous studied reported an abnormal increase in the density of mites (>5 mites/cm2) in patients affected by papulo-pustular rosacea, measured by regular and standardized superficial skin biopsy, skin scraping, PCR or reflectance confocal microscopy (RCM)3-6.

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