Prevalence profile of odontogenic cysts and tumors on Brazilian sample after the reclassification of odontogenic keratocyst

Publication date: Available online 18 December 2016
Source:Journal of Cranio-Maxillofacial Surgery
Author(s): Filipe Jaeger, Mariana Saturnino de Noronha, Maiza Luiza Vieira Silva, Márcio Bruno Figueiredo Amaral, Soraya de Mattos Carmago Grossmann, Martinho Campolina Rebello Horta, Paulo Eduardo Alencar de Souza, Maria Cássia Ferreira de Aguiar, Ricardo Alves Mesquita
PurposeThe aim of this study was to evaluate the impact of the reclassification of odontogenic keratocyst (OKC) as a tumor on the prevalence profile of odontogenic cysts (OCs) and odontogenic tumors (OTs).Study designTwo referral Oral and Maxillofacial Pathology services in Brazil were evaluated. All cases diagnosed as OCs or OTs were selected and classified according to the 1992 WHO-classification (cases before 2005 WHO classification of tumors excluding OKC) and the 2005 WHO classification of tumors, going forward including cases of odontogenic keratocyst tumor (KCOT). The frequency and prevalence of OCs and OTs were compared before and after the reclassification.ResultsAmong 27,854 oral biopsies, 4,920 (17.66%) were OCs and 992 (3.56%) were OTs. The prevalence of OTs before 2005 WHO classification of tumors was 2.04%, while the prevalence after 2005 WHO classification was 11.51% (p˂ 0.0001). Before 2006, the most frequent tumor diagnosed was odontoma with 194 cases (39.67%), and after 2005 WHO classification of tumors the KCOT was the most frequent with 207 cases (41.07%).ConclusionsThe increase in the prevelance of OTs after 2005 WHO is related to the improvement of pathology services and to the inclusion of KCOT in the OTs group.



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