Spanish Version of Actinic Keratosis Quality of Life Questionnaire (AKQoL)

Abstract

Background

Patient Reported Outcome Measures are very important outcomes. For specific diseases Health Related Quality of Life-instruments (HRQoL) are increasingly used to provide data on patients' overall perceptions of the course of a given disease. Actinic keratoses (AKs) are common keratotic lesions that occur on chronically sunlight-exposed skin. Only few studies regarding HRQoL in AKs have been made.

Objective

In order to be able to compare HRQoL among different countries and cultures we aimed to translate and validate the Actinic Keratosis Quality of Life (AKQoL) questionnaire into Spanish and quantify the impairment caused by AKs in Spanish patients.

Methods

The AKQoL was translated. Then 15 patients with AKs were interviewed to ensure cultural adaption before it was tested in one hundred patients with AK lesions at the Melanoma Unit of Hospital Clinic in Barcelona.

Results

Validation showed high inter-item correlations, as well as a high correlation of each item and the total score. Internal consistency (Cronbachs coefficient alpha) was also high at 0.91 and an alpha value of 0.90 at retest. The test-retest correlation was 0.96 and the intra class coefficient was 0.98.

Conclusion

The presented data support the AKQoL Spanish version as a valid and reliable HRQoL questionnaire for the description of AK-related QoL, and may provide a method for comparison of AK specific QoL between different cultures and countries.

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