Differentiating 131I Radiation Sialadenitis from Autoimmune (Sjogren’s Syndrome) Sialadenitis: Case Report•

Publication date: Available online 17 April 2017
Source:Journal of Oral and Maxillofacial Surgery
Author(s): Louis Mandel, Loren Wissner Greene
Radioactive iodine (131I) is used effectively for the treatment of differentiated thyroid cancers. Because it is actively secreted by the salivary glands, radiation damage to these glands can occur. Obstructive swellings, following mealtime salivary stimulation, are common occurrences. Dry mouth is not usually seen if low doses of 131I are used.A subjective complaint of xerostomia in a patient treated with 75.8 mCi 131I proved to be related to the simultaneous presence of Sjogren's syndrome (SS). Serologic, histologic, scintigraphic and salivary volume findings, along with the patient's subjective complaints, served to establish the pre-existence of SS.



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