Clinical characteristics of patients with low functional IL-6 production upon TLR/IL-1R stimulation

Publication date: Available online 5 May 2017
Source:Journal of Allergy and Clinical Immunology
Author(s): Glynis Frans, Jutte Van der Werff Ten Bosch, Leen Moens, Greet Wuyts, Heidi Schaballie, David Tuerlinckx, Mia De Bie, Francois Vermeulen, Rik Schrijvers, Wim Meert, Matthew S. Hestand, Joris Delanghe, Joris R. Vermeesch, Isabelle Meyts, Xavier Bossuyt

Teaser

Low IL-6 production upon stimulation by TLR/IL-1R ligands is associated with increased susceptibility to bacterial skin infections and to invasive infections with P. aeruginosa and/or with a IRAK-4/MyD88/NEMO defect.


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