Distraction osteogenesis after stem cell transplantation: A pioneer approach

Jan Oliver Voss, Jörg-Sven Kühl, Maike Holm, Kathrin Hauptmann, Nicolai Adolphs

Annals of Maxillofacial Surgery 2018 8(2):303-306

Allogeneic hematopoietic stem cell transplantation (HSCT) is an established therapy and is without alternative for certain groups of patients. Successful HSCT induces both long-lasting remission and tolerance without the need for further immunosuppression. In this case, cellular repair and regenerative processes work in a physiologic manner allowing elective surgical procedures, such as the interdisciplinary correction of dentofacial anomalies. Here, we report the successful management of transverse maxillary deficiency by transpalatal distraction and subsequent orthodontic treatment in a 12-year-old boy who underwent HSCT for high-risk acute lymphoblastic leukemia at 5 years of age.

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