IJERPH, Vol. 17, Pages 6783: Effects of Toxic Metal Contamination in the Tri-State Mining District on the Ecological Community and Human Health: A Systematic Review International Journal of Environmental Research and Public Health doi: 10.3390/ijerph17186783 Authors: Park Noh Min Rupar Although extensive research exists on toxic environments in the Tri-State Mining District (TSMD), there has been a lack of research on how harmful effects in TSMD could affect residents living...
Social Sciences, Vol. 9, Pages 161: Interrelations between After-School Settings and the Delinquency and Emotional-Behavioral Problems of Elementary School Children: Findings from Fragile Families and Child Wellbeing Study Social Sciences doi: 10.3390/socsci9090161 Authors: Hyejoon Park Siying Guo Shinwoo Choi Keeyoon Noh Even though there are different types of after-school settings, numerous studies have focused on formal after-school settings (i.e., after-school programs...
Nutrients, Vol. 12, Pages 2849: Association of Maternal Plasma Total Cysteine and Growth among Infants in Nepal: A Cohort Study Nutrients doi: 10.3390/nu12092849 Authors: Nikhil Arora Tor A. Strand Ram K. Chandyo Amany Elshorbagy Laxman Shrestha Per M. Ueland Manjeswori Ulak Catherine Schwinger Cysteine is a semi-essential amino acid that has been positively associated with growth in children. However, transgenerational effects remain unclear. The aim of this analysis...
Nutrients, Vol. 12, Pages 2848: Is Drinking Alcohol Really Linked to Cardiovascular Health? Evidence from the Kardiovize 2030 Project Nutrients doi: 10.3390/nu12092848 Authors: Andrea Maugeri Ota Hlinomaz Antonella Agodi Martina Barchitta Sarka Kunzova Hana Bauerova Ondrej Sochor Jose R. Medina-Inojosa Francisco Lopez-Jimenez Manlio Vinciguerra Gorazd Bernard Stokin Juan Pablo González-Rivas Existing data have described benefits and drawbacks of alcohol...
Nutrients, Vol. 12, Pages 2847: The Anti-Inflammatory Effect of Taurine on Cardiovascular Disease Nutrients doi: 10.3390/nu12092847 Authors: Tawar Qaradakhi Laura Kate Gadanec Kristen Renee McSweeney Jemma Rose Abraham Vasso Apostolopoulos Anthony Zulli Taurine is a non-protein amino acid that is expressed in the majority of animal tissues. With its unique sulfonic acid makeup, taurine influences cellular functions, including osmoregulation, antioxidation, ion movement...
Nutrients, Vol. 12, Pages 2846: Nutritional Therapy to Modulate Tryptophan Metabolism and Aryl Hydrocarbon-Receptor Signaling Activation in Human Diseases Nutrients doi: 10.3390/nu12092846 Authors: Mohammed Ghiboub Charlotte M. Verburgt Bruno Sovran Marc A. Benninga Wouter J. de Jonge Johan E. Van Limbergen The aryl hydrocarbon receptor (AhR) is a nuclear protein which, upon association with certain endogenous and exogenous ligands, translocates into the nucleus, binds...
Nutrients, Vol. 12, Pages 2850: Quercetin Supplementation Improves Neuromuscular Function Recovery from Muscle Damage Nutrients doi: 10.3390/nu12092850 Authors: Ilenia Bazzucchi Federica Patrizio Roberta Ceci Guglielmo Duranti Stefania Sabatini Paolo Sgrò Luigi Di Luigi Massimo Sacchetti This study was aimed at investigating whether quercetin (Q) may improve the recovery of neuromuscular function and biochemical parameters in the 7 days following an eccentric exercise-induced...
Toxins, Vol. 12, Pages 602: Novel Binding Mechanisms of Fusion Broad Range Anti-Infective Protein Ricin A Chain Mutant-Pokeweed Antiviral Protein 1 (RTAM-PAP1) against SARS-CoV-2 Key Proteins in Silico Toxins doi: 10.3390/toxins12090602 Authors: Yasser Hassan Sherry Ogg Hui Ge The deadly pandemic named COVID-19, caused by a new coronavirus (SARS-CoV-2), emerged in 2019 and is still spreading globally at a dangerous pace. As of today, there are no proven vaccines, therapies, or...
Nanomaterials, Vol. 10, Pages 1861: Green Synthesis, Characterization, Antimicrobial, Anti-Cancer, and Optimization of Colorimetric Sensing of Hydrogen Peroxide of Algae Extract Capped Silver Nanoparticles Nanomaterials doi: 10.3390/nano10091861 Authors: Abdelaziz Elgamouz Hamid Idriss Chahlaa Nassab Alaa Bihi Khalid Bajou Kamrul Hasan Mohammad Abu Haija Shashikant P. Patole A green and cost-effective technique for the preparation of silver nanoparticles (Algae-AgNPs)...
Nanomaterials, Vol. 10, Pages 1862: Graphitic Nanocup Architectures for Advanced Nanotechnology Applications Nanomaterials doi: 10.3390/nano10091862 Authors: Hyehee Kim Sen Gao Myung Gwan Hahm Chi Won Ahn Hyun Young Jung Yung Joon Jung The synthesis of controllable hollow graphitic architectures can engender revolutionary changes in nanotechnology. Here, we present the synthesis, processing, and possible applications of low aspect ratio hollow graphitic nanoscale architectures...
Molecules, Vol. 25, Pages 4260: Design, Synthesis and Functional Analysis of Cyclic Opioid Peptides with Dmt-Tic Pharmacophore Molecules doi: 10.3390/molecules25184260 Authors: Arijit Sarkar Anna Adamska-Bartlomiejczyk Justyna Piekielna-Ciesielska Karol Wtorek Alicja Kluczyk Attila Borics Anna Janecka The opioid receptors are members of the G-protein-coupled receptor (GPCR) family and are known to modulate a variety of biological functions, including pain perception....
Molecules, Vol. 25, Pages 4261: High Carbon Dioxide Treatment Modulates Sugar Metabolism and Maintains the Quality of Fresh-Cut Pear Fruit Molecules doi: 10.3390/molecules25184261 Authors: Wang Ma Belwal Li Li Li Luo The purpose of this study is to explore the effect of 10% carbon dioxide (CO2) on the fruit quality and sugar metabolism of fresh-cut pear during storage. The results indicated that carbon dioxide treatment maintained fruit quality by delaying the...
Vaccines, Vol. 8, Pages 538: Recognition of Dimeric Lewis X by Anti-Dimeric Lex Antibody SH2 Vaccines doi: 10.3390/vaccines8030538 Authors: Sinthuja Jegatheeswaran Ari Asnani Adam Forman Jenifer L. Hendel Christopher J. Moore Ali Nejatie An Wang Jo-Wen Wang France-Isabelle Auzanneau The carbohydrate antigen dimeric Lewis X (DimLex), which accumulates in colonic and liver adenocarcinomas, is a valuable target to develop anti-cancer therapeutics. Using the native...
IJMS, Vol. 21, Pages 6821: A Highly Conserved Iron-Sulfur Cluster Assembly Machinery between Humans and Amoeba Dictyostelium discoideum: The Characterization of Frataxin International Journal of Molecular Sciences doi: 10.3390/ijms21186821 Authors: Justo Olmos María Florencia Pignataro Ana Belén Benítez dos Santos Mauro Bringas Sebastián Klinke Laura Kamenetzky Francisco Velazquez Javier Santos Several biological activities depend on iron–sulfur clusters...
IJERPH, Vol. 17, Pages 6779: The Effect of Sports Rules Amendments on Exercise Intensity during Taekwondo-Specific Workouts International Journal of Environmental Research and Public Health doi: 10.3390/ijerph17186779 Authors: Janowski Zieliński Ciekot-Sołtysiak Schneider Kusy We aimed to compare the change in exercise response to taekwondo-specific circuit workouts before and after competition rule amendments. A total of 240 workouts in 15 elite athletes were analyzed...
IJERPH, Vol. 17, Pages 6780: SEEP-CI: A Structured Economic Evaluation Process for Complex Health System Interventions International Journal of Environmental Research and Public Health doi: 10.3390/ijerph17186780 Authors: Jason Madan Meghan Bruce Kumar Miriam Taegtmeyer Edwine Barasa Swaran Preet Singh The economic evaluation of health system interventions is challenging, and methods guidance on how to respond to these challenges is lacking. The REACHOUT consortium developed...
JCM, Vol. 9, Pages 3000: Complex Immunometabolic Profiling Reveals the Activation of Cellular Immunity and Biliary Lesions in Patients with Severe COVID-19 Journal of Clinical Medicine doi: 10.3390/jcm9093000 Authors: Adam Klocperk Marketa Bloomfield Zuzana Parackova Irena Zentsova Petra Vrabcova Jan Balko Grigorij Meseznikov Luis Fernando Casas Mendez Alzbeta Grandcourtova Jan Sipek Martin Tulach Josef Zamecnik Tomas Vymazal Anna Sediva This study...
Foods, Vol. 9, Pages 1310: Monitoring Viscosity and Total Solids Content of Milk Protein Concentrate Using an Inline Acoustic Flowmeter at Laboratory Scale Foods doi: 10.3390/foods9091310 Authors: Archana Bista John T. Tobin Colm P. O’Donnell Norah O’Shea Control of milk concentrate viscosity and total solids (TS) content prior to spray drying can improve dairy ingredient manufacture. However, the availability of hygienic and appropriately pressure rated process viscometers...
Foods, Vol. 9, Pages 1309: The Effect of Mixing Milk of Different Species on Chemical, Physicochemical, and Sensory Features of Cheeses: A Review Foods doi: 10.3390/foods9091309 Authors: Boukria El Hadrami Boudalia Safarov Leriche Aït-Kaddour The yield and quality of cheese are associated with the composition, physicochemical, sensory, rheological, and microbiological properties of milk and with the technology applied to the milk before and/or during cheese processing....
Pharmaceutics, Vol. 12, Pages 882: Enhanced Intestinal Absorption and Pharmacokinetic Modulation of Berberine and Its Metabolites through the Inhibition of P-Glycoprotein and Intestinal Metabolism in Rats Using a Berberine Mixed Micelle Formulation Pharmaceutics doi: 10.3390/pharmaceutics12090882 Authors: Mihwa Kwon Dong Yu Lim Chul Haeng Lee Ji-Hyeon Jeon Min-Koo Choi Im-Sook Song We aimed to develop a berberine formulation to enhance the intestinal absorption and plasma...
Pharmaceutics, Vol. 12, Pages 881: Cellulose/Collagen Dressings for Diabetic Foot Ulcer: A Review Pharmaceutics doi: 10.3390/pharmaceutics12090881 Authors: Ruth Naomi Mh Busra Fauzi Diabetic foot ulcer (DFU) is currently a global concern and it requires urgent attention, as the cost allocation by the government for DFU increases every year. This review was performed to provide scientific evidence on the advanced biomaterials that can be utilised as a first-line treatment for DFU patients....
Pharmaceutics, Vol. 12, Pages 883: Biodegradable Electrospun Nonwovens Releasing Propolis as a Promising Dressing Material for Burn Wound Treatment Pharmaceutics doi: 10.3390/pharmaceutics12090883 Authors: Mateusz Stojko Jakub Włodarczyk Michał Sobota Paulina Karpeta-Jarząbek Małgorzata Pastusiak Henryk Janeczek Piotr Dobrzyński Gabriela Starczynowska Arkadiusz Orchel Jerzy Stojko Olgierd Batoryna Paweł Olczyk Katarzyna Komosińska-Vassev Krystyna Olczyk...
Water, Vol. 12, Pages 2597: Changes in Geochemical Composition of Groundwater due to CO2 Leakage in Various Geological Media Water doi: 10.3390/w12092597 Authors: Jisu Jeong Sung-Wook Jeen Hyoun-Tae Hwang Kang-Kun Lee This study evaluated the effects of CO2 leakage on the geochemical composition of groundwater in various geological media through long-term column experiments. Four columns were set up with soil representing a silicate aquifer; clean sand; a sand and limestone...
Water, Vol. 12, Pages 2599: Drought Frequency Analysis Based on the Development of a Two-Variate Standardized Index (Rainfall-Runoff) Water doi: 10.3390/w12092599 Authors: Gholamreza Nikravesh Mohammad Aghababaei Mohammad Nazari-Sharabian Moses Karakouzian Drought is one of the most drastic events, which has imposed irreparable damages on human societies and may occur in any climate regime. To define drought, given its properties of multidimensionality and randomity, one cannot...
Water, Vol. 12, Pages 2598: Overview of 12 Years of Special Rapporteurs on the Human Rights to Water and Sanitation: Looking Forward to Future Challenges Water doi: 10.3390/w12092598 Authors: Léo Heller Catarina De Albuquerque Virginia Roaf Alejandro Jiménez The year 2020 marks the 10th anniversary of the United Nations (UN) resolution that recognized the human rights to water and sanitation (HRtWS), and is the last year of the second mandate of the Special Rapporteurs (SRs),...
Water, Vol. 12, Pages 2600: Kernel Extreme Learning Machine: An Efficient Model for Estimating Daily Dew Point Temperature Using Weather Data Water doi: 10.3390/w12092600 Authors: Meysam Alizamir Sungwon Kim Mohammad Zounemat-Kermani Salim Heddam Nam Won Kim Vijay P. Singh Accurate estimation of dew point temperature (Tdew) has a crucial role in sustainable water resource management. This study investigates kernel extreme learning machine (KELM), boosted regression tree...
IJMS, Vol. 21, Pages 6820: Isolated Lung Perfusion in the Management of Acute Respiratory Distress Syndrome International Journal of Molecular Sciences doi: 10.3390/ijms21186820 Authors: Nathan Haywood Matthew R. Byler Aimee Zhang Mark E. Roeser Irving L. Kron Victor E. Laubach Acute respiratory distress syndrome (ARDS) is associated with high morbidity and mortality, and current management has a dramatic impact on healthcare resource utilization. While our understanding...
IJMS, Vol. 21, Pages 6818: The Role of Exosomes in Stemness and Neurodegenerative Diseases—Chemoresistant-Cancer Therapeutics and Phytochemicals International Journal of Molecular Sciences doi: 10.3390/ijms21186818 Authors: Narasimha M. Beeraka Shalini H. Doreswamy Surya P. Sadhu Asha Srinivasan Rajeswara Rao Pragada SubbaRao V. Madhunapantula Gjumrakch Aliev Exosomes exhibit a wide range of biological properties and functions in the living organisms. They are nanometric...
IJERPH, Vol. 17, Pages 6778: Do Changes in the Local Food Environment Within New Residential Developments Influence the Diets of Residents? Longitudinal Results from RESIDE International Journal of Environmental Research and Public Health doi: 10.3390/ijerph17186778 Authors: Alexia Bivoltsis Gina Trapp Matthew Knuiman Paula Hooper Gina L. Ambrosini Background: There is limited longitudinal evidence supporting a link between food outlet locations and dietary outcomes to inform...
Molecules, Vol. 25, Pages 4259: Cytotoxicity of Oleandrin Is Mediated by Calcium Influx and by Increased Manganese Uptake in Saccharomyces cerevisiae Cells Molecules doi: 10.3390/molecules25184259 Authors: Lavinia L. Ruta Claudia V. Popa Ileana C. Farcasanu Oleandrin, the main component of Nerium oleander L. extracts, is a cardiotoxic glycoside with multiple pharmacological implications, having potential anti-tumoral and antiviral characteristics. Although it is accepted that the...
Molecules, Vol. 25, Pages 4258: A Novel Cytotoxic Conjugate Derived from the Natural Product Podophyllotoxin as a Direct-Target Protein Dual Inhibitor Molecules doi: 10.3390/molecules25184258 Authors: Ángela-Patricia Hernández Paula Díez Pablo A. García Martín Pérez-Andrés Pablo Ortega Pablo G. Jambrina David Díez María Ángeles Castro Manuel Fuentes Natural products are the ideal basis for the design of novel efficient molecular entities. Podophyllotoxin, a naturally...
Cancers, Vol. 12, Pages 2651: Cellular and Molecular Progression of Prostate Cancer: Models for Basic and Preclinical Research Cancers doi: 10.3390/cancers12092651 Authors: Sirin Saranyutanon Sachin Kumar Deshmukh Santanu Dasgupta Sachin Pai Seema Singh Ajay Pratap Singh We have witnessed noteworthy progress in our understanding of prostate cancer over the past decades. This basic knowledge has been translated into efficient diagnostic and treatment approaches leading...
Cancers, Vol. 12, Pages 2652: Cancer-Associated Fibroblasts: Versatile Players in the Tumor Microenvironment Cancers doi: 10.3390/cancers12092652 Authors: Debolina Ganguly Raghav Chandra John Karalis Martha Teke Todd Aguilera Ravikanth Maddipati Megan B. Wachsmann Dario Ghersi Giulia Siravegna Herbert J. Zeh III Rolf Brekken David T. Ting Matteo Ligorio Cancer-associated fibroblasts (CAFs) are indispensable architects of the tumor microenvironment....
Nutrients, Vol. 12, Pages 2842: Nutritional Ergogenic Aids in Racquet Sports: A Systematic Review Nutrients doi: 10.3390/nu12092842 Authors: Néstor Vicente-Salar Guillermo Santos-Sánchez Enrique Roche A nutritional ergogenic aid (NEA) can help athletes optimize performance, but an evidence-based analysis is required in order to support training outcomes or competition performance in specific events. Racquet sports players are regularly exposed to a high-intensity workload throughout...
Nutrients, Vol. 12, Pages 2845: Sex-Specific Association between Social Frailty and Diet Quality, Diet Quantity, and Nutrition in Community-Dwelling Elderly Nutrients doi: 10.3390/nu12092845 Authors: Chi Hsien Huang Kiwako Okada Eiji Matsushita Chiharu Uno Shosuke Satake Beatriz Arakawa Martins Masafumi Kuzuya The effects of social frailty on diet and nutrition are under-investigated. Our study aimed to assess the association between social frailty and diet quality,...
Membranes, Vol. 10, Pages 238: Impacts of Natural Organic Matter Adhesion on Irreversible Membrane Fouling during Surface Water Treatment Using Ultrafiltration Membranes doi: 10.3390/membranes10090238 Authors: Fangshu Qu Zhimeng Yang Shanshan Gao Huarong Yu Junguo He Hongwei Rong Jiayu Tian To understand impacts of organic adhesion on membrane fouling, ultrafiltration (UF) membrane fouling by dissolved natural organic matter (NOM) was investigated in the presence of...
Nanomaterials, Vol. 10, Pages 1860: Functionalization of Molybdenum Disulfide via Plasma Treatment and 3-Mercaptopropionic Acid for Gas Sensors Nanomaterials doi: 10.3390/nano10091860 Authors: Won Seok Seo Dae Ki Kim Ji-Hoon Han Kang-Bak Park Su Chak Ryu Nam Ki Min Joon Hyub Kim Monolayer and multilayer molybdenum disulfide (MoS2) materials are semiconductors with direct/indirect bandgaps of 1.2–1.8 eV and are attractive due to their changes in response to...
Nanomaterials, Vol. 10, Pages 1859: Abatement of the Stimulatory Effect of Copper Nanoparticles Supported on Titania on Ovarian Cell Functions by Some Plants and Phytochemicals Nanomaterials doi: 10.3390/nano10091859 Authors: Alexander V. Sirotkin Monika Radosová Adam Tarko Zuzana Fabova Iris Martín-García Francisco Alonso The application of nanoparticles has experienced a vertiginous growth, but their interaction with food and medicinal plants in organisms, especially...
Arts, Vol. 9, Pages 96: Animals from Motya: Depictions and Archaeological Evidence in the Phoenician Town in Sicily Arts doi: 10.3390/arts9030096 Authors: Francesca Oliveri Maria Pamela Toti This paper focusses on the animal presence in the archaeological records from the Phoenician island town of Motya (Sicily), which grew to prosperity from its settlement in the 8th century until its destruction in 397 bce. Offering a preliminary review of this material, the paper discusses fantastic...
J. Imaging, Vol. 6, Pages 97: Understanding the Effects of Optimal Combination of Spectral Bands on Deep Learning Model Predictions: A Case Study Based on Permafrost Tundra Landform Mapping Using High Resolution Multispectral Satellite Imagery Journal of Imaging doi: 10.3390/jimaging6090097 Authors: Md Abul Ehsan Bhuiyan Chandi Witharana Anna K. Liljedahl Benjamin M. Jones Ronald Daanen Howard E. Epstein Kelcy Kent Claire G. Griffin Amber Agnew Deep learning (DL)...
Biomolecules, Vol. 10, Pages 1329: The Receptor Tyrosine Kinase TrkA Is Increased and Targetable in HER2-Positive Breast Cancer Biomolecules doi: 10.3390/biom10091329 Authors: Nathan Griffin Mark Marsland Severine Roselli Christopher Oldmeadow John Attia Marjorie M. Walker Hubert Hondermarck Sam Faulkner The tyrosine kinase receptor A (NTRK1/TrkA) is increasingly regarded as a therapeutic target in oncology. In breast cancer, TrkA contributes to metastasis but the...
IJERPH, Vol. 17, Pages 6776: Indoor Radon Measurements Using Radon Track Detectors and Electret Ionization Chambers in the Bauxite-Bearing Areas of Southern Adamawa, Cameroon International Journal of Environmental Research and Public Health doi: 10.3390/ijerph17186776 Authors: Saïdou Oumar Bobbo Modibo Ndjana Nkoulou Ii Joseph Emmanuel Olga German Kountchou Noube Michaux Hamadou Yerima Abba The current work deals with indoor radon (222Rn) concentrations and ambient dose-equivalent...
IJERPH, Vol. 17, Pages 6777: Lack of Association between the Reasons for and Time Spent Doing Physical Activity International Journal of Environmental Research and Public Health doi: 10.3390/ijerph17186777 Authors: Màrius Domínguez-Amorós Pilar Aparicio-Chueca Low levels of Physical Activity (PA) and sedentarism are associated with the onset of different pathologies and health problems. Regular physical activity has been linked with being beneficial to the health of the general population....
Antioxidants, Vol. 9, Pages 879: Vitamin C and E Treatment Blunts Sprint Interval Training–Induced Changes in Inflammatory Mediator-, Calcium-, and Mitochondria-Related Signaling in Recreationally Active Elderly Humans Antioxidants doi: 10.3390/antiox9090879 Authors: Victoria L. Wyckelsma Tomas Venckunas Marius Brazaitis Stefano Gastaldello Audrius Snieckus Nerijus Eimantas Neringa Baranauskiene Andrejus Subocius Albertas Skurvydas Mati Pääsuke Helena Gapeyeva...
Antioxidants, Vol. 9, Pages 878: Antioxidant Profile of Pepper (Capsicum annuum L.) Fruits Containing Diverse Levels of Capsaicinoids Antioxidants doi: 10.3390/antiox9090878 Authors: José M. Palma Fátima Terán Alba Contreras-Ruiz Marta Rodríguez-Ruiz Francisco J. Corpas Capsicum is the genus where a number of species and varieties have pungent features due to the exclusive content of capsaicinoids such as capsaicin and dihydrocapsaicin. In this work, the main enzymatic and...
Antioxidants, Vol. 9, Pages 877: N-Acetylaspartylglutamate (NAAG) Pretreatment Reduces Hypoxic-Ischemic Brain Damage and Oxidative Stress in Neonatal Rats Antioxidants doi: 10.3390/antiox9090877 Authors: Ewelina Bratek Apolonia Ziembowicz Elzbieta Salinska N-acetylaspartylglutamate (NAAG), the most abundant peptide transmitter in the mammalian nervous system, activates mGluR3 at presynaptic sites, inhibiting the release of glutamate, and acts on mGluR3 on astrocytes, stimulating...
Atmosphere, Vol. 11, Pages 994: Helicopter Pilots Encountering Fog: An Analysis of 109 Accidents from 1992 to 2016 Atmosphere doi: 10.3390/atmos11090994 Authors: Alex de Voogt Hilary Kalagher Andrew Diamond Helicopters have the ability to make maneuvers or precautionary off-airport landings to avoid flights into instrument meteorological conditions (IMC) such as fog. Flight accidents in which fog was encountered as well as inadvertent and intentional flights into fog were examined...
Cells, Vol. 9, Pages 2112: Visualizing Cell Cycle Phase Organization and Control During Neural Lineage Elaboration Cells doi: 10.3390/cells9092112 Authors: Fatma Rabia Urun Adrian W Moore In neural precursors, cell cycle regulators simultaneously control both progression through the cell cycle and the probability of a cell fate switch. Precursors act in lineages, where they transition through a series of cell types, each of which has a unique molecular identity and cellular behavior....
Cells, Vol. 9, Pages 2113: Hyaluronic Acid Biomaterials for Central Nervous System Regenerative Medicine Cells doi: 10.3390/cells9092113 Authors: Gregory Jensen Julianne L. Holloway Sarah E. Stabenfeldt Hyaluronic acid (HA) is a primary component of the brain extracellular matrix and functions through cellular receptors to regulate cell behavior within the central nervous system (CNS). These behaviors, such as migration, proliferation, differentiation, and inflammation contribute...
Cells, Vol. 9, Pages 2114: Hedgehog Signaling and Truncated GLI1 in Cancer Cells doi: 10.3390/cells9092114 Authors: Daniel Doheny Sara G. Manore Grace L. Wong Hui-Wen Lo The hedgehog (HH) signaling pathway regulates normal cell growth and differentiation. As a consequence of improper control, aberrant HH signaling results in tumorigenesis and supports aggressive phenotypes of human cancers, such as neoplastic transformation, tumor progression, metastasis, and drug resistance....
Diversity, Vol. 12, Pages 358: A Hot Spot of Olive Biodiversity in the Tunisian Oasis of Degache Diversity doi: 10.3390/d12090358 Authors: Olfa Saddoud Deddabi Cinzia Montemurro Sihem Ben Maachia Fathi Ben Amar Valentina Fanelli Susanna Gadaleta Milad El Riachy Ali Chehade Mona Siblini Saliah Boucheffa Monica Marilena Miazzi Tunisia is one of the world’s largest producers of olive oil, and it preserves pools of olive genetic diversity that are...
Brain Sciences, Vol. 10, Pages 642: Evaluation of Automatic Segmentation of Thalamic Nuclei through Clinical Effects Using Directional Deep Brain Stimulation Leads: A Technical Note Brain Sciences doi: 10.3390/brainsci10090642 Authors: Marie T. Krüger Rebecca Kurtev-Rittstieg Georg Kägi Yashar Naseri Stefan Hägele-Link Florian Brugger Automatic anatomical segmentation of patients’ anatomical structures and modeling of the volume of tissue activated (VTA) can...
Water, Vol. 12, Pages 2595: Satellites HY-1C and Landsat 8 Combined to Observe the Influence of Bridge on Sea Surface Temperature and Suspended Sediment Concentration in Hangzhou Bay, China Water doi: 10.3390/w12092595 Authors: Shuyi Huang Jianqiang Liu Lina Cai Minrui Zhou Juan Bu Jieni Xu We analyzed the influence of a cross-sea bridge on the sea surface temperature (SST) and suspended sediment concentration (SSC) of Hangzhou Bay based on landsat8_TIRS data and HY-1C...
Water, Vol. 12, Pages 2596: A Nation-Wide Framework for Evaluating Freshwater Health in China: Background, Administration, and Indicators Water doi: 10.3390/w12092596 Authors: Chen Xie Yifan Yang Yang Liu Guoqing Liu Ziwu Fan Yun Li This study reviewed the existing experience of implementing the nation-wide freshwater health evaluation in China and around the world and proposes a new framework that works in collaboration with the River Chief System (RCS). The institutional...
IJMS, Vol. 21, Pages 6816: The Emerging Role of ATP-Dependent Chromatin Remodeling in Memory and Substance Use Disorders International Journal of Molecular Sciences doi: 10.3390/ijms21186816 Authors: Alberto J. López Julia K. Hecking André O. White Long-term memory formation requires coordinated regulation of gene expression and persistent changes in cell function. For decades, research has implicated histone modifications in regulating chromatin compaction necessary for experience-dependent...
IJMS, Vol. 21, Pages 6817: Genome-Wide Analysis Reveals Dynamic Epigenomic Differences in Soybean Response to Low-Phosphorus Stress International Journal of Molecular Sciences doi: 10.3390/ijms21186817 Authors: Shanshan Chu Xiangqian Zhang Kaiye Yu Lingling Lv Chongyuan Sun Xiaoqian Liu Jinyu Zhang Yongqing Jiao Dan Zhang Low-phosphorus (low-P) stress has a significant limiting effect on crop yield and quality. Although the molecular mechanisms of the transcriptional...
IJERPH, Vol. 17, Pages 6774: Risk of Glaucoma in Patients Receiving Hemodialysis and Peritoneal Dialysis: A Nationwide Population-Based Cohort Study International Journal of Environmental Research and Public Health doi: 10.3390/ijerph17186774 Authors: Chen-Chee Lim Chia-Yi Lee Fu-Chin Huang Jing-Yang Huang Jia-Horung Hung Shun-Fa Yang This paper investigated the incidence and risk of newly diagnosed glaucoma after the initiation of maintenance dialysis in Taiwan. A case–control...
IJERPH, Vol. 17, Pages 6773: Tuberculosis Infection Screening in 5468 Italian Healthcare Students: Investigation of a Borderline Zone Value for the QFT-Test International Journal of Environmental Research and Public Health doi: 10.3390/ijerph17186773 Authors: Anna Rita Corvino Maria Grazia Lourdes Monaco Elpidio Maria Garzillo Elena Grimaldi Giovanna Donnarumma Nadia Miraglia Gabriella Di Giuseppe Monica Lamberti Healthcare workers are at an increased risk of contracting...
IJERPH, Vol. 17, Pages 6772: Frailty Status Typologies in Spanish Older Population: Associations with Successful Aging International Journal of Environmental Research and Public Health doi: 10.3390/ijerph17186772 Authors: José M. Tomás Trinidad Sentandreu-Mañó Irene Fernández Background: Defining frailty typologies would contribute to guiding specific care interventions. These typologies could additionally be related to different health outcomes. This study aims at identifying...
IJERPH, Vol. 17, Pages 6775: Neonatal Lead (Pb) Exposure and DNA Methylation Profiles in Dried Bloodspots International Journal of Environmental Research and Public Health doi: 10.3390/ijerph17186775 Authors: Luke Montrose Jaclyn M. Goodrich Masako Morishita Joseph Kochmanski Zachary Klaver Raymond Cavalcante Julie C. Lumeng Karen E. Peterson Dana C. Dolinoy Lead (Pb) exposure remains a major concern in the United States (US) and around the world, even following...
Nutrients, Vol. 12, Pages 2843: Metabolic Health in Obese Subjects—Is There a Link to Lactoferrin and Lactoferrin Receptor-Related Gene Polymorphisms? Nutrients doi: 10.3390/nu12092843 Authors: Małgorzata Jamka Nina Kaczmarek Edyta Mądry Patrycja Krzyżanowska-Jankowska Joanna Bajerska Matylda Kręgielska-Narożna Paweł Bogdański Jarosław Walkowiak This study aimed to evaluate the association of genetic variants in lactoferrin (LTF) metabolism-related genes with the...
Nutrients, Vol. 12, Pages 2844: Methylglyoxal Decoration of Glutenin during Heat Processing Could Alleviate the Resulting Allergic Reaction in Mice Nutrients doi: 10.3390/nu12092844 Authors: Yaya Wang Xiang Li Sihao Wu Lu Dong Yaozhong Hu Junping Wang Yan Zhang Shuo Wang Background: It is widely believed that Maillard reactions could affect the sensitization of allergens. However, the mechanism of action of methylglyoxal (MGO) production in Maillard reactions in...
Nanomaterials, Vol. 10, Pages 1858: Mixed Mercaptocarboxylic Acid Shells Provide Stable Dispersions of InPZnS/ZnSe/ZnS Multishell Quantum Dots in Aqueous Media Nanomaterials doi: 10.3390/nano10091858 Authors: Benjamin Heyne Kristin Arlt André Geßner Alexander F. Richter Markus Döblinger Jochen Feldmann Andreas Taubert Armin Wedel Highly luminescent indium phosphide zinc sulfide (InPZnS) quantum dots (QDs), with zinc selenide/zinc sulfide (ZnSe/ZnS) shells, were synthesized....
Biomolecules, Vol. 10, Pages 1328: Oxygen: The Rate-Limiting Factor for Episodic Memory Performance, Even in Healthy Young Individuals Biomolecules doi: 10.3390/biom10091328 Authors: Gil Suzin Tom Halpert Frolinger Dror Yogev Amir Hadanny Merav Catalogna Yuri Rassovsky Shai Efrati Cognition is a crucial element of human functionality. Like any other physical capability, cognition is both enabled and limited by tissue biology. The aim of this study was to investigate...
JCM, Vol. 9, Pages 2998: Growth Differentiation Factor 15 in Severe Aortic Valve Stenosis: Relationship with Left Ventricular Remodeling and Frailty Journal of Clinical Medicine doi: 10.3390/jcm9092998 Authors: Iacopo Fabiani Tatiana Santoni Marco Angelillis Serena Petricciuolo Andrea Colli Giovanni Pellegrini Deborah Mazzei Nicola Riccardo Pugliese Anna Sonia Petronio Raffaele De Caterina Background: Frailty is an important outcome predictor in patients with...
Toxics, Vol. 8, Pages 70: Polychlorinated Biphenyls (PCBs): Risk Factors for Autism Spectrum Disorder? Toxics doi: 10.3390/toxics8030070 Authors: Harmanpreet Kaur Panesar Conner L. Kennedy Kimberly P. Keil Stietz Pamela J. Lein Autism spectrum disorder (ASD) includes a group of multifactorial neurodevelopmental disorders defined clinically by core deficits in social reciprocity and communication, restrictive interests and repetitive behaviors. ASD affects one in 54 children...
Atmosphere, Vol. 11, Pages 993: Assessment of Children’s Potential Exposure to Bioburden in Indoor Environments Atmosphere doi: 10.3390/atmos11090993 Authors: Carla Viegas Beatriz Almeida Marta Dias Liliana Aranha Caetano Elisabete Carolino Anita Quintal Gomes Tiago Faria Vânia Martins Susana Marta Almeida The exposure to particles and bioaerosols has been associated with the increase in health effects in children. The objective of this study was to assess the...
Microorganisms, Vol. 8, Pages 1426: Correction: Saarinen, N.V.V., et al. Multiplexed High-Throughput Serological Assay for Human Enteroviruses. Microorganismis 2020, 8, 963 Microorganisms doi: 10.3390/microorganisms8091426 Authors: Niila Saarinen Jussi Lehtonen Riitta Veijola Johanna Lempainen Mikael Knip Heikki Hyöty Olli Laitinen Vesa Hytönen The authors wish to make the following corrections to this paper [...]
Biomimetics, Vol. 5, Pages 45: Facile Synthesis of Antimicrobial Aloe Vera-“Smart” Triiodide-PVP Biomaterials Biomimetics doi: 10.3390/biomimetics5030045 Authors: Zehra Edis Samir Haj Bloukh Antibiotic resistance is an eminent threat for the survival of mankind. Nosocomial infections caused by multidrug resistant microorganisms are a reason for morbidity and mortality worldwide. Plant-based antimicrobial agents are based on synergistic mechanisms which prevent resistance and have...
IJMS, Vol. 21, Pages 6815: Cooperativity between the Ribosome-Associated Chaperone Ssb/RAC and the Ubiquitin Ligase Ltn1 in Ubiquitination of Nascent Polypeptides International Journal of Molecular Sciences doi: 10.3390/ijms21186815 Authors: Arnab Ghosh Natalia Shcherbik Eukaryotic cells have evolved multiple mechanisms to detect and eliminate aberrant polypeptides. Co-translational protein surveillance systems play an important role in these mechanisms. These systems include ribosome-associated...
Plants, Vol. 9, Pages 1217: Soil Organic Matter Degradation in Long-Term Maize Cultivation and Insufficient Organic Fertilization Plants doi: 10.3390/plants9091217 Authors: Jiří Balík Martin Kulhánek Jindřich Černý Ondřej Sedlář Pavel Suran Soil organic matter carbon (CSOM) compounds degradation was observed in long-term field experiments with silage maize monoculture. Over a period of 26 years, the content of carbon in topsoil decreased by 22% in control unfertilized plots...
IJERPH, Vol. 17, Pages 6770: The Effects of Parental Absence on Children Development: Evidence from Left-Behind Children in China International Journal of Environmental Research and Public Health doi: 10.3390/ijerph17186770 Authors: Mingzhi Mao Lijun Zang Haifeng Zhang Parental care in early childhood is viewed as one of the most important factors that help foster children’s abilities. Using two nationally representative datasets collected in China, this paper examines...
IJERPH, Vol. 17, Pages 6769: Perception of Dating Violence in Teenage Couples: A Cross Validation Study in Spain and Colombia International Journal of Environmental Research and Public Health doi: 10.3390/ijerph17186769 Authors: Ana Martínez-Dorado Jesús Privado Sergio A. Useche Lilian Velasco Dau García-Dauder Elisa Alfaro Background: dating violence, or violence in teenage couples, is a socially interesting topic, due to its prevalence and its possible use in predicting...
IJERPH, Vol. 17, Pages 6771: Does Mental Well-Being Protect against Self-Harm Thoughts and Behaviors during Adolescence? A Six-Month Prospective Investigation International Journal of Environmental Research and Public Health doi: 10.3390/ijerph17186771 Authors: Kirsten Russell Susan Rasmussen Simon C. Hunter Mental well-being protects against the emergence of suicidal thoughts. However, it is not clear whether these findings extend to self-harm thoughts and behaviors irrespective...
Antibiotics, Vol. 9, Pages 612: Synthesis, ADMET Properties, and In Vitro Antimicrobial and Antibiofilm Activity of 5-Nitro-2-thiophenecarbaldehyde N-((E)-(5-Nitrothienyl)methylidene)hydrazone (KTU-286) against Staphylococcus aureus with Defined Resistance Mechanisms Antibiotics doi: 10.3390/antibiotics9090612 Authors: Povilas Kavaliauskas Birute Grybaite Vytautas Mickevicius Ruta Petraitiene Ramune Grigaleviciute Rita Planciuniene Philip Gialanella Alius Pockevicius Vidmantas...
Nutrients, Vol. 12, Pages 2841: An In-Depth Exploration of Knowledge and Beliefs Associated with Soda and Diet Soda Consumption Nutrients doi: 10.3390/nu12092841 Authors: Caroline Miller Kerry Ettridge Melanie Wakefield Simone Pettigrew John Coveney David Roder Sarah Durkin Gary Wittert Jane Martin Joanne Dono The need to reduce sugar-sweetened beverage (SSB) consumption is widely accepted, but whether artificially sweetened beverages (ASBs) are a recommended...
JoF, Vol. 6, Pages 173: Host Immune Defense upon Fungal Infections with Mucorales: Pathogen-Immune Cell Interactions as Drivers of Inflammatory Responses Journal of Fungi doi: 10.3390/jof6030173 Authors: Dolly E. Montaño Kerstin Voigt During the last few decades, mucormycosis has emerged as one of the most common fungal infections, following candidiasis and aspergillosis. The fungal order responsible for causing mucormycosis is the Mucorales. The main hallmarks of this infection include...
Pharmacy, Vol. 8, Pages 173: Drug Utilisation and Off-Label Use on a German Neonatal Intensive Care Unit: A Retrospective Cohort Study and 10-Year Comparison Pharmacy doi: 10.3390/pharmacy8030173 Authors: Carmen Geißler Christopher Schulze Sebastian Botzenhardt Wolfgang Rascher Antje Neubert Pharmacotherapy of neonates is complex and marked to a large extent of off-label use. The implementation of the Paediatric Regulation (2007) gave hope for a change in the safety and efficacy...
JCM, Vol. 9, Pages 2997: Diagnosis, Treatment and Prevention of Sarcopenia in Hip Fractured Patients: Where We Are and Where We Are Going: A Systematic Review Journal of Clinical Medicine doi: 10.3390/jcm9092997 Authors: Gianluca Testa Andrea Vescio Danilo Zuccalà Vincenzo Petrantoni Mirko Amico Giorgio Ivan Russo Giuseppe Sessa Vito Pavone Background: Sarcopenia is defined as a progressive loss of muscle mass and muscle strength associated to increased adverse events,...
JCM, Vol. 9, Pages 2999: Ductal Carcinoma In Situ Underestimation of Microcalcifications Only by Stereotactic Vacuum-Assisted Breast Biopsy: A New Predictor of Specimens without Microcalcifications Journal of Clinical Medicine doi: 10.3390/jcm9092999 Authors: Yun-Chung Cheung Shin-Cheh Chen Shir-Hwa Ueng Chi-Chang Yu The mammographic appearance of ductal carcinoma in situ (DCIS) is mostly observed as microcalcifications. Although stereotactic vacuum-assisted breast biopsy (VABB)...
Toxins, Vol. 12, Pages 601: Introduction to the Toxins Special Issue on Botulinum Neurotoxins in the Nervous System: Future Challenges for Novel Indications Toxins doi: 10.3390/toxins12090601 Authors: Siro Luvisetto Botulinum toxins (BoNTs) are a true wonder of nature [...]
Nanomaterials, Vol. 10, Pages 1857: Patchy Core/Shell, Magnetite/Silver Nanoparticles via Green and Facile Synthesis: Routes to Assure Biocompatibility Nanomaterials doi: 10.3390/nano10091857 Authors: Carlos M. Ramírez-Acosta Javier Cifuentes Juan C. Cruz Luis H. Reyes Nanomedicine is entering a high maturity stage and is ready to reach full translation into the clinical practice. This is because of the ample spectrum of applications enabled by a large arsenal of nanostructured...
IJMS, Vol. 21, Pages 6814: Correction: Cui, H., et al. BA-12 Inhibits Angiogenesis via Glutathione Metabolism Activation. Int. J. Mol. Sci. 2019, 20, 4062 International Journal of Molecular Sciences doi: 10.3390/ijms21186814 Authors: Herong Cui Wenbo Guo Beibei Zhang Guoping Li Tong Li Yanyan Yuan Na Zhang Yuwei Yang Wuwen Feng Fuhao Chu Shenglan Wang Bing Xu Penglong Wang Haimin Lei The authors wish to make the following corrections to this paper...
IJMS, Vol. 21, Pages 6813: Age, Sex Hormones, and Circadian Rhythm Regulate the Expression of Amyloid-Beta Scavengers at the Choroid Plexus International Journal of Molecular Sciences doi: 10.3390/ijms21186813 Authors: Ana C. Duarte André Furtado Mariya V. Hrynchak Ana R. Costa Daniela Talhada Isabel Gonçalves Manuel C. Lemos Telma Quintela Cecília R.A. Santos Accumulation of amyloid-beta (Aβ) in the brain is thought to derive from the impairment of Aβ...
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