The use of a chitosan-derived haemostatic agent for post-extraction bleeding control in patients on anti-platelet treatment

Publication date: Available online 18 January 2017
Source:Journal of Oral and Maxillofacial Surgery
Author(s): Roberto Pippi, Marcello Santoro, Arturo Cafolla
PurposeThe current approach for tooth extraction in patients receiving anti-platelet treatment requires the use of local haemostatic agents without previous thromboembolic treatment interruption. The aim of the present study was to evaluate the effectiveness of an extra-alveolar haemostatic agent, the HemCon® Dental Dressing (HDD), in controlling post-surgical bleeding.MethodsRoutine, atraumatic tooth extractions were performed in a single session under local anesthesia without vasoconstrictor and without APT interruption. All patients underwent the extraction of two teeth in the same session, each one in a different dental hemi-arch and the haemostatic method to be used was randomly chosen: in the test site (SH), the HDD was applied, whereas in the control site (SX), a common haemostatic sponge (CollaPlug, Zimmer Dental) was applied and stabilized in situ with a suture. For each surgery, two different times were measured: the time required for haemostatic agent application (T1) and the time required for haemostasis achievement (T2). Post-operative pain and healing quality was also evaluated.ResultsTwenty out-patients were enrolled. The mean application time was significantly lower in the test group than in the control group; the mean bleeding time in the control group was significantly lower than in the test group; pain values was lower in the test group than in the control group, especially at suture removal; post-extraction socket healing was better in the test group than in the control group.ConclusionHDD seems therefore to be a valid and safe alternative in treating post-extraction sockets in out-patients under single drug anti-platelet treatment, in the absence of surgical wound lacerations.



http://ift.tt/2iIwbRW