Increased IL-13 expression is independently associated with neo-osteogenesis in chronic rhinosinusitis

Publication date: Available online 7 June 2017
Source:Journal of Allergy and Clinical Immunology
Author(s): Sakiko Oue, Mahnaz Ramezanpour, Sathish Paramasivan, Dijana Miljkovic, Clare M. Cooksley, Ahmed Bassiouni, Judy Ou, Alkis J. Psaltis, Peter-John Wormald, Sarah Vreugde

Teaser

Capsule Summary: Increased expression of IL-13 is independently affected by the neo-osteogenesis state in CRS. IL-13 protein increased osteoblastic bone mineralization in vitro. Our findings indicate that IL-13 may contribute to pathological bone remodelling in recalcitrant CRS.


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