Abstract Despite higher stages at presentation, patients with high-risk (HR) HPV-related (HPV+) head and neck squamous cell carcinomas (HNSCCs) have better survival rates compared to those with non-HPV-related (HPV−) disease. However, significant comorbidity and the number of patients who suffer failed treatment, recurrent disease, late metastasis, and death are increasing along with the incidence of HPV+ HNSCC. A cytotoxic T-cell-dependent immune response is required to clear...
Sat Jun 20, 2020 03:00
Abstract Thyroid carcinomas represent 3.2% of all new cases of cancer in the United States. Whereas most thyroid tumors arise from follicular cells or, less commonly, parafollicular cells, the derivation of some rare primary thyroid carcinoma subtypes is less clear and represents an area of evolving knowledge. Primary thyroid carcinomas that resemble neoplasms characteristic of the salivary glands (“salivary-like” primary thyroid carcinomas) arguably represent some of the most...
Fri Jun 19, 2020 03:00
Abstract The significance of granuloma and amyloid deposition in primary nasopharyngeal carcinoma (NPC) has yet to be investigated. This study aimed to evaluate their clinicopathologic associations. The histopathologic findings of 747 consecutive patients with primary NPC were retrospectively reviewed between January 2001 and December 2015. The presence of granulomas and amyloid deposits was observed in 68 (9.1%) and 62 (8.3%) patients, respectively. Granulomas were significantly...
Fri Jun 19, 2020 03:00
Related Articles Head and neck squamous cell carcinoma in solid organ transplant recipients. Eur Arch Otorhinolaryngol. 2020 Jun 19;: Authors: Fernández-Carrera González I, Ibarra Estupiñan C, Rivero Fernández I, Sanz Rodríguez M, García González E, Almodóvar Álvarez C, Gavilanes-Plasencia J Abstract PURPOSE: Characterize head and neck squamous cell carcinomas in solid transplant recipients and compare outcomes with non-transplanted population....
Sun Jun 21, 2020 14:35
Related Articles First results of electrode reimplantation and its hypothetical dependence from artificial brain maturation. Eur Arch Otorhinolaryngol. 2020 Jun 19;: Authors: Roßberg W, Timm M, Matin F, Zanoni A, Krüger C, Giourgas A, Bültmann E, Lenarz T, Kral A, Lesinski-Schiedat A Abstract BACKGROUND: After introducing the first Cochlear Implants also in children theses are grown with electrical intracochlear stimulation and subsequent auditory...
Sun Jun 21, 2020 14:35
Related Articles Correction to: The role of eABR with intracochlear test electrode in decision making between cochlear and brainstem implants: preliminary results. Eur Arch Otorhinolaryngol. 2020 Jun 19;: Authors: Cinar BC, Yarali M, Atay G, Bajin MD, Sennaroglu G, Sennaroglu L Abstract In the original publication of the article, the ethical approval number was published incorrectly as GO 14/195-30. The correct number is GO 14/580-21. Hence,...
Sun Jun 21, 2020 14:35
Related Articles Assessing the abilities of senior otolaryngology residents and graduated otolaryngologists in recognizing skull base elements in axial CT scan: proposing a new method for differentiating superior orbital fissure and optic canal. Eur Arch Otorhinolaryngol. 2020 Jun 19;: Authors: Mohammadzadeh M, Abdullah H, Davoodian A, Akbari A, Erfanian R Abstract BACKGROUND AND OBJECTIVES: The aim of this study was to evaluate the ability...
Sun Jun 21, 2020 14:35
Related Articles Prematurity and associated future paediatric airway pathology: experience from a single tertiary paediatric ENT centre. Eur Arch Otorhinolaryngol. 2020 Jun 15;: Authors: Vakharia N, Maity A, Bajaj G, Bajaj Y, Hall A Abstract PURPOSE: Enhanced management of the pre-term patient has resulted in improved survival rates in increasingly premature patients. Although prematurity predisposes to congenital airway pathology, there is...
Sat Jun 20, 2020 14:58
Related Articles Tracheostomy care and decannulation during the COVID-19 pandemic. A multidisciplinary clinical practice guideline. Eur Arch Otorhinolaryngol. 2020 Jun 17;: Authors: Rovira A, Dawson D, Walker A, Tornari C, Dinham A, Foden N, Surda P, Archer S, Lonsdale D, Ball J, Ofo E, Karagama Y, Odutoye T, Little S, Simo R, Arora A Abstract PURPOSE: Traditional critical care dogma regarding the benefits of early tracheostomy during invasive...
Sat Jun 20, 2020 14:58
Related Articles The impact of bariatric surgery on eustachian tube dysfunction. Eur Arch Otorhinolaryngol. 2020 Jun 15;: Authors: Yazici ZM, Gunes S, Koc RH, Gunes ME, Sayin İ Abstract PURPOSE: We aimed to evaluate the relationship between acute loss of weight after 6 months of bariatric surgery and the occurrence of tubal dysfunction symptoms METHODS: We recruited 76 patients who had undergone bariatric surgery between 2018 and 2019. It was...
Sat Jun 20, 2020 14:58
Related Articles Device-related epistaxis risk: continuous-flow left ventricular assist device-supported patients. Eur Arch Otorhinolaryngol. 2020 Jun 15;: Authors: Koycu A, Vural O, Bahcecitapar M, Jafarov S, Beyazpinar G, Beyazpinar DS Abstract BACKGROUND: The aim of this study was to analyze the effect of device-dependent factors on epistaxis episodes comparing patients supported with a continuous-flow left ventricular assist device (CF-LVAD)...
Sat Jun 20, 2020 14:58
Related Articles Analysis of cochlear implant revision surgeries. Eur Arch Otorhinolaryngol. 2020 Jun 15;: Authors: Gumus B, İncesulu AS, Kaya E, Kezban Gurbuz M, Ozgur Pınarbaslı M Abstract PURPOSE: This study aimed to evaluate the reasons for cochlear implant (CI) revision surgeries in pediatric and adult groups. METHODS: A total of 490 CIs were used for 423 patients between August 2005 and August 2019. Among these, patients who underwent...
Sat Jun 20, 2020 14:58
Related Articles Histological type homogeneity: a cornerstone in analyzing temporal bone malignancies data. Eur Arch Otorhinolaryngol. 2020 Jun 17;: Authors: Franz L, Zanoletti E, Mazzoni A, Marioni G PMID: 32556784 [PubMed - as supplied by publisher]
Sat Jun 20, 2020 14:58
Related Articles Benign paroxysmal positional vertigo as a complication of 90-day head-down bed rest. Eur Arch Otorhinolaryngol. 2020 Jun 16;: Authors: Wang L, Liu J, Fan Q, Fan Z, Xu X, Li Z, Dai Z, Qu L, Li Y Abstract PURPOSE: This study aimed to report the occurrence of benign paroxysmal positional vertigo (BPPV) in a 90-day head-down bed rest experiment and evaluate the potential relationship between BPPV-related seizures and bone metabolic...
Sat Jun 20, 2020 14:58
Related Articles Reply to "Indications and timing for tracheostomy in patients with SARS CoV2-related" by Ferri et al. Eur Arch Otorhinolaryngol. 2020 Jun 17;: Authors: Mattioli F, Marudi A, Ghirelli M, Molteni G, Sgarbi N, Valerini S, Girardis M, Presutti L, Fermi M PMID: 32556782 [PubMed - as supplied by publisher]
Sat Jun 20, 2020 14:58
Related Articles Olfactory and gustatory dysfunctions due to the coronavirus disease (COVID-19): a review of current evidence. Eur Arch Otorhinolaryngol. 2020 Jun 17;: Authors: Mehraeen E, Behnezhad F, Salehi MA, Noori T, Harandi H, SeyedAlinaghi S Abstract INTRODUCTION: It is reported that coronavirus disease (COVID-19) can affect the sense of smell and taste of infected people. The pathobiology of this virus is still incompletely known, and...
Sat Jun 20, 2020 14:58
Related Articles Optimizing classical risk scores to predict complications in head and neck surgery: a new approach. Eur Arch Otorhinolaryngol. 2020 Jun 18;: Authors: Sousa Menezes A, Fernandes A, Rocha Rodrigues J, Salomé C, Machado F, Antunes L, Castro Silva J, Monteiro E, Lara Santos L Abstract PURPOSE: To validate tools to identify patients at risk for perioperative complications to implement prehabilitation programmes in head and neck surgery...
Sat Jun 20, 2020 14:58
J Neurol Surg B Skull BaseDOI: 10.1055/s-0040-1713100 Background Transpetrosal approaches have become standard technique for resection of petroclival meningiomas (PCM). The retrosigmoid craniotomy has also been extensively studied as an alternative approach. The need to resect the tentorium at the end of a retrosigmoid approach has been described, but the upfront transtentorial variation of the retrosigmoid craniotomy has never been described nor evaluated in detail as a possible alternative...
Fri Jun 19, 2020 02:00
J Neurol Surg B Skull BaseDOI: 10.1055/s-0040-1713108 Background Recently the endoscopic endonasal surgery (EES) has been introduced as a modality for the treatment of patients with craniopharyngiomas. In this study, we describe our initial experience in treatment of 29 patients with craniopharyngiomas using this approach. Methods Twenty-nine consecutive patients with craniopharyngiomas who had undergone EES in a 5-year period were studied retrospectively. Patients underwent...
Fri Jun 19, 2020 02:00
J Neurol Surg B Skull BaseDOI: 10.1055/s-0040-1713101 Background Transorbital neuroendoscopic (TONES) approaches promise to open up new horizons for skull base surgery, offering alternative routes to reach the anterior and middle cranial fossa (ACF and MCF, respectively). Objective The aim of this anatomical study is to acquire new surgical anatomy knowledge and exploit it for the refinement of TONES approaches, as an alternative to open surgery, to reduce the distance to...
Fri Jun 19, 2020 02:00
J Neurol Surg B Skull BaseDOI: 10.1055/s-0040-1713106 Objectives The pterygopalatine fossa (PPF) is a narrow space situated posterior to the maxillary sinus. While external approaches have been used to treat tumors of the PPF, recent endoscopic approaches have become favored as an alternative; we developed an endoscopic tri-port approach, which provides wide surgical corridor with minimal invasion, for PPF. This report aims to introduce and verify the new approach. Design Case...
Fri Jun 19, 2020 02:00
J Neurol Surg B Skull BaseDOI: 10.1055/s-0040-1713104 Introduction Pituitary apoplexy commonly presents with visual and hormonal deficits. While traditionally regarded as an emergency, there have been increasing trends toward conservative management. Our institutional practice consists of early surgery; therefore, we reviewed our series evaluating vision outcomes, hormone function, and complications compared with the present literature. Methods We retrospectively reviewed...
Fri Jun 19, 2020 02:00
LaryngorhinootologieDOI: 10.1055/a-1177-1240 Hintergrund Berufsbildungswerke (BBW) sind Einrichtungen der beruflichen Rehabilitation und Bildung, vergleichbar mit Förderschulen im schulischen Bereich. Das BBW Leipzig registriert seit einigen Jahren eine zunehmende Anzahl von Jugendlichen mit der Diagnose auditive Verarbeitungs- und Wahrnehmungsstörung (AVWS). Für diese Zielgruppe gibt es derzeit nur wenige Testverfahren mit Referenz- oder Normwerten. Ziel war die Untersuchung der auditiven...
Fri Jun 19, 2020 02:00
Thyroid, Ahead of Print.
Fri Jun 19, 2020 10:00
Thyroid, Ahead of Print.
Fri Jun 19, 2020 10:00
Hypothesis: There may be findings peculiar to the temporal bones of children with Down's syndrome (DS). The purpose of this study is to investigate the temporal bone histopathology of the children with DS. Background: Otitis media with effusion is a highly prevalent condition with DS. Knowledge of the volume of the tympanic compartments and the area of the tympanic isthmus might be important to find out the pathogenesis of highly prevalent otitis media with effusion in those patients. Methods:...
Fri Jun 19, 2020 03:00
Hypothesis: Generic guidelines for insertion depth of precurved electrodes are suboptimal for many individuals. Background: Insertion depths that are too shallow result in decreased cochlear coverage, and ones that are too deep lift electrodes away from the modiolus and degrade the electro-neural interface. Guidelines for insertion depth are generically applied to all individuals using insertion depth markers on the array that can be referenced against anatomical landmarks. Methods:...
Fri Jun 19, 2020 03:00
Objectives: Primary: to compare, in vitro, the antimicrobial activity of different antiseptic agents versus quinolone drops, against the common organisms of chronic otitis media. Secondary: to examine the possible role of pH on the antimicrobial activity of the antiseptic solutions. Methods: Three antiseptic powders (boric acid; iodine; and a 1:1 combination of these two) and four solutions (2% boric acid; 2% acetic acid; 3.25% aluminum acetate; and 5% povidone iodine) were tested...
Fri Jun 19, 2020 03:00
Background: Obstructive sleep apnea is a highly prevalent disorder often treated with continuous positive airway pressure (CPAP). CPAP transmits high pressures through the Eustachian tube, and has significant implications for patients undergoing surgery of the middle ear, inner ear, and lateral skull base. In such patients, nothing is known regarding the likelihood of surgical complications with CPAP use, or medical complications with its cessation. No consensus or guidelines exist for postoperative...
Fri Jun 19, 2020 03:00
Objective: To identify trends in the quality of otology studies published in general otolaryngology journals over a 20-year period. Study Design: Retrospective analysis. Methods: Otologic and neurotologic papers from 1997, 2007, and 2017 were identified in the three general otolaryngology journals with the highest Eigenfactor scores: the Laryngoscope, European Archives of Otorhinolaryngology, and Otolaryngology–Head and Neck Surgery. The studies were reviewed and assigned level...
Fri Jun 19, 2020 03:00
Objective: To determine risk factors for readmission, prolonged length of stay, and discharge to a rehabilitation facility in patients with acute mastoiditis. Trends in treatment and complication rates were also examined. Study Design: Retrospective cohort study. Setting: Nationwide Readmissions Database (2013, 2014). Patients: Pediatric and adult patients in the Nationwide Readmissions Database with a primary diagnosis of acute mastoiditis. Interventions: ...
Fri Jun 19, 2020 03:00
No abstract available
Fri Jun 19, 2020 03:00
Objectives: Brain volumetric declines may underlie the association between hearing loss and dementia. While much is known about the peripheral auditory function and brain volumetric declines, poorer central auditory speech processing may also be associated with decreases in brain volumes. Methods: Central auditory speech processing, measured by the speech recognition threshold (SRT) from the Digits-in-Noise task, and neuroimaging assessments (structural magnetic resonance imaging [MRI]...
Fri Jun 19, 2020 03:00
Objective: Posterior external auditory canal (EAC) hypesthesia (Hitselberger's sign) has been previously described to occur in all vestibular schwannomas (1966) but has not been studied since. We hypothesized that sensory loss may be related to tumor size and sought to determine if this clinical sign could predict preoperative characteristics of vestibular schwannomas, intraoperative findings, and/or surgical outcomes. Study Design: Prospective observational study. Setting: ...
Fri Jun 19, 2020 03:00
No abstract available
Fri Jun 19, 2020 03:00
Hypothesis: Whereas autophagy has been linked to various human diseases, whether it also plays a role in cholesteatoma is virtually unknown. This study aimed to investigate the activity and regulation of autophagy in cholesteatoma. Background: The treatment of middle ear cholesteatoma has been challenging due to an insufficient understanding of the underlying disease mechanism. Methods: Expression of microtubule-associated protein 1A/1B-light chain 3 (LC3), the autophagy protein...
Fri Jun 19, 2020 03:00
Objective: To review insights gained from a 21-year experience with gentamicin-induced vestibulotoxicity including differences in vestibulotoxicity between single daily dosing (SDD) and multiple daily dosing (MDD) regimens. Study Design: Retrospective case series. Setting: Tertiary care center. Patients: Patients with gentamicin vestibulotoxicity referred to the Hertz Multidisciplinary Neurotology Clinic between January 1993 and September 2014. Intervention: ...
Fri Jun 19, 2020 03:00
Background: Cochlear implantation with preservation of residual low-frequency hearing enables patients to utilize acoustic and electrical stimulation. It is widely accepted that preservation of residual low-frequency hearing is beneficial in both background noise and for music appreciation. The extent to which patients may benefit is not fully understood, but the importance of these concepts is reflected in electrode design developments and also refinement of surgical technique. Greater understanding...
Fri Jun 19, 2020 03:00
Objective: Vestibular evoked myogenic potentials (VEMPs) are short-latency muscle potentials measured from the neck (cervical VEMP; cVEMP) or under the eyes (ocular VEMP; oVEMP), which provide information regarding function of the saccule and utricle, respectively. VEMPs are reliable when performed in adults; however, reliability of VEMPs in children is unknown. Therefore, the purpose of the study was to determine the test-retest reliability of c- and oVEMP testing in normal control children....
Fri Jun 19, 2020 03:00
No abstract available
Fri Jun 19, 2020 03:00
Objective: To evaluate auditory manifestations in children born to mothers who had exanthema during pregnancy, suspected to have been exposed to the Zika virus (ZIKV). Study Design: Prospective observational. Setting: Tertiary referral center. Patients: Children born in Rio de Janeiro, Brazil, between April 2016 and September 2017, who were referred for newborn hearing screening (NHS). Intervention: The NHS was performed by the automated brainstem auditory-evoked...
Fri Jun 19, 2020 03:00
Introduction: Many individuals have some residual hearing which should be preserved with cochlear implantation. To achieve this goal electrode arrays must fulfil certain design requirements. A new thin lateral wall electrode array (HiFocus SlimJ) was systematically designed on the basis of μCT studies of human cochlea anatomy. The primary objective of this study was to report on initial retrospective hearing preservation results from a cohort of subjects consecutively implanted with this electrode....
Fri Jun 19, 2020 03:00
Hypothesis: An augmented reality (AR) platform using a head mounted display (HMD) can successfully display and register virtual computerized tomography (CT) data to corresponding real world anatomy using fiducial markers. Background: AR is a growing field in surgical planning, and has been used by this group to aide in orthopedic surgery applications. Intraoperative AR registration of preoperative CT images could improve identification of critical anatomical structures during lateral...
Fri Jun 19, 2020 03:00
Objective: To assess for changes in trends of the disease process, management, and outcomes of necrotizing otitis externa (NOE) over the last decade. Data Sources: Articles in English, published between January 2011 and June 2019, were searched in PubMed, Scopus, Web of Science, ScienceDirect, and the Cochrane Database. Study Selection: Inclusion criteria: 1) reported evidence of NOE, 2) details on patient demographic and underlying medical disorder, 3) details on treatments,...
Fri Jun 19, 2020 03:00
Objective: The number of small to medium sized vestibular schwannoma (VS) patients presenting with serviceable hearing has steadily increased. There are various treatment strategies for small to medium sized VS, including microsurgery (MS), gamma knife radiosurgery (GKS), and serial observations using magnetic resonance imaging. In this study, we presented the long-term outcomes of patients with small to medium sized VS with serviceable hearing. We also evaluated the potential prognostic factors...
Fri Jun 19, 2020 03:00
Aim: To evaluate OTOPLAN software in the surgical planning of far-advanced otosclerosis (FAO) candidates to cochlear implant (CI) were considered. We aimed to preliminarily investigate if this software could influence the electrode length choice, or predict surgical difficulties. Methods: We reviewed the outcome of five consecutive FAO patients that underwent unilateral CI. OTOPLAN was used to evaluate preoperative computed tomography imaging. A comparison was made with historical data...
Fri Jun 19, 2020 03:00
Objective: A decrease in intracochlear electrocochleographic (ECochG) amplitude during cochlear implantation has been associated with poorer postoperative hearing preservation in several short-term studies. Here, we relate the stability of ECochG during surgery to hearing preservation at 3- and 12-months. Methods: Patients with hearing ≤80-dB HL at 500 Hz were implanted with a slim-straight electrode array. ECochG responses to short, high-intensity, 500-Hz pure tones of alternating...
Fri Jun 19, 2020 03:00
Objective: Evaluate opioid prescribing patterns following tympanoplasty/mastoidectomy and assess factors associated to recurrent opioid use. Study Design: Retrospective cohort study. Setting: National pharmaceutical database recording opioid fulfillment (Truven Health Marketscan Commercial Claims/Encounters and Medicare Claims/Encounters database). Participants: Patients who 1) underwent tympanoplasty and/or mastoidectomy, 2) filled postoperative opioid prescriptions...
Fri Jun 19, 2020 03:00
Objective: The purpose of this study was to systematically evaluate the literature to evaluate the rate of and associated factors with aberrant facial nerve stimulation (AFNS) following cochlear implantation. Additionally, management strategies for AFNS were assessed. Data Sources: A systematic search was performed in PubMed, Cochrane Database of Systematic Reviews, and Web of Science to identify peer reviewed research. Study Selection: Eligible studies were those containing...
Fri Jun 19, 2020 03:00
Objective: To evaluate the treatment outcomes of nimodipine and steroid combination therapy for idiopathic sudden sensorineural hearing loss (ISSNHL). Study Design: Retrospective case review. Setting: Tertiary referral center. Patients: Seventy-eight patients who were diagnosed with ISSNHL were divided into two group based on the treatment strategies used: steroid+nimodipine (SN, n = 36) and steroid only (SO, n = 42) groups. Based on the level of hearing loss before...
Fri Jun 19, 2020 03:00
Objectives: Sudden sensorineural hearing loss (SSNHL) may occur in post-irradiated nasopharyngeal carcinoma (NPC) survivors with a rare rate. This study was conducted to evaluate the clinical characteristics and prognosis of this population. Study Design: Retrospective cohort study. Setting: Tertiary otology referral center. Patients: Five hundred ninety nine SSNHL patients were recruited between January 2010 and January 2019. Patients were divided into two groups:...
Fri Jun 19, 2020 03:00
Objectives: To predict postoperative cochlear implant performance with heterogeneous text and numerical variables using supervised machine learning techniques. Study Design: A supervised machine learning approach comprising neural networks and decision tree-based ensemble algorithms were used to predict 1-year postoperative cochlear implant performance based on retrospective data. Setting: Tertiary referral center. Patients: One thousand six hundred four adults who...
Fri Jun 19, 2020 03:00
Objective: To determine if symptoms regarding timing and triggers of dizziness are useful for categorizing patients with dizziness, and to evaluate how patient-reported symptoms predict vestibular asymmetry, postural sway, and vestibular diagnoses. Study Design: Retrospective chart review. Setting: Tertiary referral center. Patients: Patients referred for suspected vestibular disease. Interventions: Patients completed a symptom questionnaire before laboratory...
Fri Jun 19, 2020 03:00
Objective: Quantify the benefit of cochlear implantation (CI) for tinnitus relief among individuals with single-sided deafness (SSD). Data Sources: PubMed, Scopus, and Cochrane databases were searched through July 10, 2019. Search strategies used a combination of subject headings (e.g., MeSH in PubMed) and keywords for the following three concepts: single-sided deafness, cochlear implantation, and tinnitus. Study Selection: English articles that reported the preintervention...
Fri Jun 19, 2020 03:00
Objective: To review a single surgeon's experience with T-tube placement through cartilage tympanoplasty versus native tympanic membrane for long-term ventilation of the chronic ear and residual perforation rates following tube removal. Study Design: Retrospective chart review. Setting: Two tertiary referral centers. Patients: One hundred sixteen patients (4–71 yr of age) who underwent either total island cartilage tympanoplasty or posterior palisade cartilage tympanoplasty...
Fri Jun 19, 2020 03:00
Objective: To elucidate the impact of hearing loss on patient health literacy. Study Design: Prospective, cross-sectional study. Setting: Academic otology practice at a university hospital. Patients: Consecutive, adult, English-speaking patients. Main Outcome Measures: Inadequate health literacy, defined as a composite score of less than or equal to nine on the brief health literacy screen (BHLS), was compared with patient hearing data utilizing the American...
Fri Jun 19, 2020 03:00
Objective: Sound processor loading times after bone-anchored hearing implant (BAHI) surgery have gradually decreased over time. This study assessed patient preferences in loading time. Study Design: Prospective patient questionnaire study. Setting: Tertiary referral center. Patients: Patients indicated for BAHI surgery received two questionnaires preoperatively: the validated Glasgow Health Status Inventory (GHSI) and a nonvalidated questionnaire that assessed patient...
Fri Jun 19, 2020 03:00
Objective: To evaluate opioid prescribing patterns following cochlear implantation (CI) and assess factors associated with recurrent opioid use. Study Design: Retrospective cohort study. Setting: National pharmaceutical database recording opioid fulfillment (Truven Health Marketscan Commercial Claims and Encounters and Medicare Claims and Encounters database) Participants: CI recipients who filled opioid prescriptions between January 2011 and December 2016. All patients...
Fri Jun 19, 2020 03:00
Objective: To discuss the natural history and management of pneumolabyrinth, with particular attention to illustrative cases where hearing improved after a fluid-filled vestibule was restored. Patients: Adults at two academic medical centers with documented pneumolabyrinth on computed tomography (CT) imaging. Intervention: Middle ear surgery or observation. Main Outcome Measures: Cochlear and vestibular symptoms are reported. Inner ear function was documented with...
Fri Jun 19, 2020 03:00
Hypothesis: Nitinol is a suitable material for passive middle ear prosthesis. Background: In modern ear microsurgery, the restitution of hearing is tremendously important. In passive ossicular reconstruction, rigid alloplastic materials are widespread in use. However, rigid prostheses fail to adapt to atmospheric pressure changes. We describe the use of the super-elastic material nitinol in passive ossicular reconstruction to overcome this limitation. Methods: Together with...
Fri Jun 19, 2020 03:00
Hypotheses: Adult cochlear implant (CI) outcomes depend on demographic, sensory, and cognitive factors. However, these factors have not been examined together comprehensively for relations to different outcome types, such as speech recognition versus quality of life (QOL). Three hypotheses were tested: 1) speech recognition will be explained most strongly by sensory factors, whereas QOL will be explained more strongly by cognitive factors. 2) Different speech recognition outcome domains (sentences...
Fri Jun 19, 2020 03:00
Objective: To investigate the disturbance induced in the cochlea during cochleostomy using conventional drill and a hand guided robotic drill. Study Design: The study is based on experimental measurements using the Laser Doppler Vibrometer during the drilling processes converted to Sound Pressure Levels (SPL) for comparison. Setting: The study is based on experimental results of three sets of cochleostomies on human cadaver heads. Main Outcome Measure(s): Robotic drilling,...
Fri Jun 19, 2020 03:00
Publication date: Available online 18 June 2020Source: Annales françaises d'Oto-rhino-laryngologie et de Pathologie Cervico-facialeAuthor(s): François Rubin, Jean-François Vellin, Julie Berkaoui, Wared Al Assaf, Angelo Pennica, Benoit Girard, Patrick Hoarau, Philippe Pescatori, Marie Dupre, Serge Bensoussan, Philippe Vurpillot, Nicolas Challut, Ollivier Laccourreye
Fri Jun 19, 2020 18:58
Induced Hypoglossal Dysfunction as a Cause of Obstructive Sleep Apnea in Mefloquine‐Exposed Veterans
Sat Jun 20, 2020 20:03
Objective To investigate predictive parameters at baseline and during the early response to sublingual immunotherapy (SLIT) for house dust mites in allergic rhinitis patients. Study Design Retrospective cohort study. Methods Patients were treated with SLIT for at least 3 years and serological tests performed at baseline and at 1‐year follow‐up to investigate predictive parameters. Satisfaction with SLIT, 4 nasal symptoms, and quality of life were evaluated before and after 3 years of...
Sat Jun 20, 2020 17:28
Systemic disease is an uncommon cause of subglottic stenosis (SGS). We report a case of severe SGS due to underlying eosinophilic granulomatosis with polyangiitis (EGPA) in a child presenting with isolated stridor. EGPA is a rare systemic vasculitis with very limited cases reported in the pediatric population. While surgical intervention was required given the degree of stenosis in this case, medical management of the underlying systemic disease process is critical when there is clinical suspicion...
Sat Jun 20, 2020 17:15
Objectives Application of transcartilage needle electrode for intraoperative neuromonitoring (IONM) during thyroidectomy has been considered an alternative method of electromyography (EMG) tube recording. However, needle electrodes must be inserted into both sides of the thyroid cartilage with exposure of the cartilage lamina. We sought to evaluate the feasibility of applying a single ipsilateral transcartilage needle electrode for IONM during unilateral hemithyroidectomy. Methods Thirty‐four...
Sat Jun 20, 2020 16:44
Objectives/Hypothesis Several recent studies have observed a high incidence of duodenoscope microbial contamination and an association of contamination with healthcare‐acquired infections. This study sought to quantify nasopharyngoscope microbial contamination relative to that of other endoscope categories and characterize the manufacturers, outcomes, and microbial profiles associated with these cases. Study Design Retrospective, cross‐sectional study. Methods A total of 3,865 adverse...
Fri Jun 19, 2020 17:05
Objectives To validate stage nodal (N)3 of the 8th edition American Joint Committee on Cancer (AJCC) staging system for nasopharyngeal carcinoma (NPC). Methods This retrospective cohort study extracted NPC patients from the Surveillance, Epidemiology, and End Results database between 2004 and 2016. Pathologically confirmed patients with complete data of level IV, N3a, and N3b lymph node metastasis were investigated. The included patients were divided into level IV, N3a, and N3b groups. Five‐year...
Thu Jun 18, 2020 22:00
Thu Jun 18, 2020 21:54
Thu Jun 18, 2020 21:48
Objectives Spontaneous cerebrospinal fluid (CSF) leaks are a rare but insidious clinical entity. In the recent literature, their pathogenesis has been linked with idiopathic intracranial hypertension (IIH). Considering a worse surgical outcome compared to traumatic leaks, a medical treatment of the underlying IIH has been suggested in order to prevent relapses. Nevertheless, some aspects of this rare pathology remain unclear. We report our long experience in the management of spontaneous CSF leaks....
Thu Jun 18, 2020 21:34
Objective To evaluated the efficacy and safety of in‐office potassium titanyl phosphate (KTP) laser treatment for the management of epistaxis in hereditary hemorrhagic telangiectasia (HHT) patients. Methods A retrospective case series of all HHT patients over age of 18 who underwent in‐office KTP laser treatment from July 1, 2017 to December 31, 2019 was performed. The primary outcome measure was the epistaxis severity score (ESS) pre‐ and post‐procedure. Secondary outcome measures included...
Thu Jun 18, 2020 21:29
Publication date: Available online 19 June 2020Source: Acta Otorrinolaringologica (English Edition)Author(s): Pedro Díaz de Cerio Canduela, Eduardo Ferrandis Perepérez, Pablo Parente Arias, Fernando López Álvarez, Jon Alexander Sistiaga Suarez, en representación de la Comisión de cabeza y cuello y base de cráneo de la SEORL-CCC
Sat Jun 20, 2020 18:47
AbstractRecent anecdotal and scientific reports have provided evidence of a link between COVID-19 and chemosensory impairments such as anosmia. However, these reports have downplayed or failed to distinguish potential effects on taste, ignored chemesthesis, and generally lacked quantitative measurements. Here, we report the development, implementation and initial results of a multi-lingual, international questionnaire to assess self-reported quantity and quality of perception in three distinct chemosensory...
Sat Jun 20, 2020 03:00
Abstract Objectives We assessed fibroblast growth factor (FGF) regenerative efficacy in an aged vocal fold rat model and confirmed it in a prospective clinical trial. Design, Setting, and Participants For animal experiments, 48 Sprague‐Dawley rats were divided into two groups: 24 six‐month‐olds (young group) and 24 twenty‐four‐month‐olds (old group). FGF was injected once a week thrice into the left vocal fold of the old group, dividing them into two sub‐groups (injected [left] and uninjected...
Thu Jun 18, 2020 11:51
Conditions: Obstructive Sleep Apnea-hypopnea; Oropharyngeal CancerIntervention: Sponsor: Poitiers University HospitalNot yet recruiting
Fri Jun 19, 2020 16:25
Condition: Parkinson DiseaseInterventions: Other: Baseline assessment of demographic, anthropometric and clinical characteristics; Other: Locomotor assessments; Other: Speech assessments; Other: Audiology assessmentsSponsors: University Hospital, Ghent; University GhentRecruiting
Fri Jun 19, 2020 16:25
Conditions: Esophageal Squamous Cell Carcinoma; Neoadjuvant Therapy; SurgeryIntervention: Sponsor: Sichuan Cancer Hospital and Research InstituteNot yet recruiting
Fri Jun 19, 2020 16:25
Medical practices around the country are balancing the need to provide necessary care while minimizing risk to patients and health... The post Providing Safe Otorhinolaryngology Care During the COVID-19 Pandemic appeared first on Otorhinolaryngology - Head & Neck Surgery.
Sun Jun 21, 2020 00:17
Angela Smith had long suffered from nasal obstruction and a nonstop runny nose that disrupted her sleep. Medical therapy and... The post Minimally Invasive Nasal Remodeling Procedure Allows Patients with Obstruction to Breathe More Easily appeared first on Otorhinolaryngology - Head & Neck Surgery.
Sun Jun 21, 2020 00:14
Douglas Stanley, MD, was named by his peers among Super Doctors Rising Stars® in Texas. Following an extensive independent nomination... The post Dr. Douglas Stanley Named a 2020 Texas Super Doctors Rising Star appeared first on Otorhinolaryngology - Head & Neck Surgery.
Sun Jun 21, 2020 00:08
Ronda Alexander, MD, an assistant professor and director of residency training in the Department of Otorhinolaryngology-Head and Neck Surgery at... The post Dr. Ronda Alexander Named Among Exceptional Women in Medicine appeared first on Otorhinolaryngology - Head & Neck Surgery.
Sun Jun 21, 2020 00:05
Abstract Hidradenitis suppurativa (HS) is a chronic inflammatory disease associated with insulin resistance (IR). Retinol binding protein 4 (RBP4) and ghrelin are two bioactive proteins that have been involved in glucose metabolism and IR, but also in the regulation of immune and inflammatory processes.The aim of this study was to determine the serum levels of RBP4 and ghrelin in patients with HS, and toassessthe possiblerelationship between these levels andIR, disease severity and HS risk. A total...
Sun Jun 21, 2020 12:02
Abstract Background Patients receiving chemoradiotherapy for head and neck cancer (HNC) are often malnourished. We assessed the utility of nutritional risk index (NRI) in HNC patients undergoing chemoradiotherapy. Methods A population‐based retrospective review of HNC patients treated with curative chemoradiation was performed. Demographics, anthropometrics, overall survival (OS), and the composite treatment complication rate (G‐tube dependence, radiation incompletion, 90‐day mortality,...
Sat Jun 20, 2020 22:48
Abstract The COVID‐19 pandemic has profoundly disrupted head and neck cancer (HNC) care delivery in ways that will likely persist long term. As we scan the horizon, this crisis has the potential to amplify preexisting racial/ethnic disparities for patients with HNC. Potential drivers of disparate HNC survival resulting from the pandemic include (a) differential access to telemedicine, timely diagnosis, and treatment; (b) implicit bias in initiatives to triage, prioritize, and schedule HNC‐directed...
Sat Jun 20, 2020 22:40
Abstract Background To prescribe early trismus therapy, prognostic factors influencing the restricted mouth opening should be identified first. Our aim is to present an overview of these factors in patients with head and neck cancer. Methods PubMed, Cochrane, EMBASE, and CINAHL were searched using terms related to head and neck cancer and mouth opening. Risk of bias was assessed using the “Quality in Prognosis Studies” tool. A best evidence synthesis was performed. Results Of the...
Thu Jun 18, 2020 21:54
Abstract Background Management of head and neck cancers (HNC) in radiation oncology in the coronavirus disease 2019 (COVID‐19) era is challenging. Aim of our work is to report organization strategies at a radiation therapy (RT) department in the first European area experiencing the COVID‐19 pandemic. Methods We focused on (a) dedicated procedures for HNC, (b) RT scheduling, and (c) health care professionals' protection applied during the COVID‐19 breakdown (from March 1, 2020 to April 30,...
Thu Jun 18, 2020 20:34
Abstract Despite higher stages at presentation, patients with high-risk (HR) HPV-related (HPV+) head and neck squamous cell carcinomas (HNSCCs) have better survival rates compared to those with non-HPV-related (HPV−) disease. However, significant comorbidity and the number of patients who suffer failed treatment, recurrent disease, late metastasis, and death are increasing along with the incidence of HPV+ HNSCC. A cytotoxic T-cell-dependent immune response is required to clear...
Sat Jun 20, 2020 03:00
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