Related Articles Predicting Metastasis in Melanoma by Enumerating Circulating Tumor Cells Using Photoacoustic Flow Cytometry. Lasers Surg Med. 2020 Jun 18;: Authors: Edgar RH, Tarhini A, Sander C, Sanders ME, Cook JL, Viator JA Abstract BACKGROUND AND OBJECTIVES: Enumerating circulating tumor cells has been used as a method of monitoring progression of various cancers. Various methods for detecting circulating melanoma cells (CMCs) have been...
Sat Jun 20, 2020 14:16
Related Articles Tipifarnib in recurrent, metastatic HRAS-mutant salivary gland cancer. Cancer. 2020 Jun 18;: Authors: Hanna GJ, Guenette JP, Chau NG, Sayehli CM, Wilhelm C, Metcalf R, Wong DJ, Brose M, Razaq M, Pérez-Ruiz E, Cohen EEW, Aggarwal R, Scholz C, Gualberto A, Ho AL Abstract BACKGROUND: To the authors' knowledge, there are no approved therapies for recurrent, metastatic (R/M) salivary gland carcinoma (SGC), but molecularly targeted...
Sat Jun 20, 2020 14:16
Related Articles Diffuse skeletal muscle extramedullary plasmacytomas: a rare case and review of the literature. Skeletal Radiol. 2020 Jun 19;: Authors: Moore RD, Nelson SM, Cecava ND Abstract Extramedullary plasmacytomas are rare neoplasms arising from proliferations of monoclonal plasma cells. In primary form, these malignancies occur without other sites of plasma cell disease. Secondary extramedullary plasmacytomas occur in association with...
Sat Jun 20, 2020 14:16
The effects of 20-kDa human placental GH in male and female GH deficient mice: an improved human GH?
Related Articles The effects of 20-kDa human placental GH in male and female GH deficient mice: an improved human GH? Endocrinology. 2020 Jun 18;: Authors: List EO, Berryman DE, Basu R, Buchman M, Funk K, Kulkarni P, Duran-Ortiz S, Qian Y, Jensen EA, Young JA, Yildirim G, Yakar S, Kopchick JJ Abstract A rare 20K isoform of GH-V (here abbreviated GHv) was discovered in 1998. To date, only one research article has characterized this isoform in...
Sat Jun 20, 2020 14:16
Related Articles Two Histologically Different Primary Malignancies: Synchronous Obstructive Descending Colon Adenocarcinoma and Appendicular Carcinoid Tumor. Am J Case Rep. 2020 Jun 19;21:e921810 Authors: Alshammari T, Alshammari S, Hakami R, Alali M, Aljohani T, Zayed MA, Bin Traiki T Abstract BACKGROUND Synchronous primary tumors are defined as 2 or more different histological tumors discovered in one patient at the same time or within a period...
Sat Jun 20, 2020 14:16
Related Articles Epstein-Barr Virus-negative Marginal Zone Lymphoma as an Uncommon Form of Monomorphic Posttransplant Lymphoproliferative Disorder. Am J Surg Pathol. 2020 Jun 16;: Authors: Galera P, Flavin R, Savage NM, Saksena A, Gong S, Wang HY, Swan N, Xi L, Raffeld M, Pittaluga S, Jaffe ES Abstract Monomorphic posttransplant lymphoproliferative disorders have been defined as lymphoid or plasmacytic proliferations that fulfill criteria for...
Sat Jun 20, 2020 14:16
Related Articles LC-FACSeq is a method for detecting rare clones in leukemia. JCI Insight. 2020 Jun 18;5(12): Authors: Hu EY, Blachly JS, Saygin C, Ozer HG, Workman SE, Lozanski A, Doong TJ, Chiang CL, Bhat S, Rogers KA, Woyach JA, Coombes KR, Jones D, Muthusamy N, Lozanski G, Byrd JC Abstract Detecting, characterizing, and monitoring rare populations of cells can increase testing sensitivity, give insight into disease mechanism, and inform...
Sat Jun 20, 2020 14:16
Related Articles The acquired von Willebrand syndrome focused for hematologists. Haematologica. 2020 Jun 18;: Authors: Franchini M, Mannucci PM Abstract The acquired von Willebrand syndrome (AVWS) is a rare bleeding disorder with laboratory findings similar to those of inherited von Willebrand disease. However, unlike the inherited disease, the AVWS occurs in persons with no personal or family history of bleeding and is often associated with...
Sat Jun 20, 2020 14:16
Related Articles Using an Interactive App for Symptom Reporting and Management Following Pancreatic Cancer Surgery to Facilitate Person-Centered Care: Descriptive Study. JMIR Mhealth Uhealth. 2020 Jun 17;8(6):e17855 Authors: Gustavell T, Sundberg K, Langius-Eklöf A Abstract BACKGROUND: Pancreatic and periampullary cancers are rare but have high mortality rates. The only hope for cure is surgical removal of the tumor. Following pancreatic surgery,...
Sat Jun 20, 2020 14:16
Related Articles Pediatric differentiated thyroid carcinoma: An update from the APSA Cancer Committee. J Pediatr Surg. 2020 May 11;: Authors: Christison-Lagay ER, Baertschiger RM, Dinauer C, Francis GL, Malek MM, Lautz TB, Aldrink JH, Grant C, Rhee DS, Ehrlich P, Dasgupta R, Abdessalam S, APSA Cancer Committee Abstract BACKGROUND: Differentiated thyroid carcinomas (DTCs) are rare in young children but represent almost 10% of all malignancies...
Sat Jun 20, 2020 14:16
Related Articles [Clinical Significance of FGFR1 Gene Abnormalities in Blood Tumors]. Zhongguo Shi Yan Xue Ye Xue Za Zhi. 2020 Jun;28(3):983-988 Authors: Zhang CL, Tang GS, Guo MQ, Cheng H, Liu MD, Yang JM, Gong SL Abstract OBJECTIVE: To study the potential significance and clinical application of FGFR1 gene abnormality in the diagnosis, clinical features, pathological mechanism and treatment in hematological tumors. METHODS: Clinical...
Sat Jun 20, 2020 14:16
Related Articles Tumefactive Demyelinating Lesions in Children: A Rare Case of Conus Medullaris Involvement and Systematic Review of the Literature. J Child Neurol. 2020 Jun 19;:883073820924147 Authors: Pérez CA, Patnaik A, Oommen S, Redko A, Mathis SB Abstract Tumefactive demyelinating lesions are an uncommon manifestation of demyelinating disease that mimic primary central nervous system neoplasms and can pose a diagnostic challenge in patients...
Sat Jun 20, 2020 14:16
Related Articles Routine Postoperative Hemoglobin Assessment Poorly PredictsTransfusion Requirement among Patients Undergoing Minimally Invasive Radical Prostatectomy. Urol Pract. 2020 Jul;7(4):299-304 Authors: Chesnut GT, Benfante N, Barham D, Dean LW, Tin A, Sjoberg DD, Scardino PT, Eastham JA, Ehdaie B, Coleman JA, Donahue TF, Touijer KA, Laudone VP Abstract Introduction: An advantage of minimally invasive radical prostatectomy over open...
Sat Jun 20, 2020 13:13
Related Articles Cardiac Autotransplantation with Concurrent Pneumonectomy for Complete Resection of Primary Cardiac Intimal Sarcoma. Korean J Thorac Cardiovasc Surg. 2020 Jun 05;53(3):140-143 Authors: Ku MJ, Kim SW, Lee S, Chang JW, Lee J, Jeong DS Abstract Primary cardiac sarcoma is rare, and intimal sarcoma is an extremely rare and highly lethal disease. We report a case of a 62-year-old woman who was incidentally diagnosed with a primary...
Sat Jun 20, 2020 13:13
Related Articles A Rare Cause of Cough: Tracheobronchial Myxoid Spindle Cell Lipoma. Case Rep Pulmonol. 2020;2020:9727281 Authors: Rodriguez JA, Weil CR, Ramirez JF Abstract Background: Endobronchial lipomas are a particularly rare form of benign lung neoplasms, with an incidence of 0.1-0.4%. They are often clinically silent, though present with nonspecific symptoms that can result in extensive workup or significant delay prior to diagnosis,...
Sat Jun 20, 2020 13:13
Related Articles Typical presentation of pulmonary lepidic adenocarcinoma: a rare case report. Pan Afr Med J. 2020;36:11 Authors: Azzeddine R, Rhorfi IA, Zegmout A, Souhi H, Elouazzani H, Abid A, Chahdi H, Tbouda M Abstract Bronchioloalveolar carcinoma (BAC) is a rare subtype of adenocarcinoma of lung with distinct features and distinctive characteristics. It accounts approximately for 4% of lung cancers. In the following study we report a rare...
Sat Jun 20, 2020 13:13
Related Articles Cisplatin plus pemetrexed therapy and subsequent immune checkpoint inhibitor administration for malignant peritoneal mesothelioma without pleural lesions: Case report. Medicine (Baltimore). 2020 May 29;99(22):e19956 Authors: Ikushima H, Sakatani T, Ohara S, Takeshima H, Horiuchi H, Morikawa T, Usui K Abstract RATIONALE: Malignant peritoneal mesothelioma is a rare tumor with a poor prognosis and has no recommended therapy after...
Sat Jun 20, 2020 13:13
Related Articles Primary malignant melanoma of the esophagus with multiple lymph node metastases: A case report and literature review. Medicine (Baltimore). 2020 May 29;99(22):e18573 Authors: Iwasaki K, Ota Y, Yamada E, Takahashi K, Watanabe T, Makuuchi Y, Suda T, Osaka Y, Seshimo A, Katsumata K, Tsuchida A Abstract RATIONALE: Primary malignant melanoma of the esophagus (PMME) is a very rare malignancy accounting for only 0.1% to 0.2% of all...
Sat Jun 20, 2020 13:13
Related Articles A nomogram to predict metastasis of soft tissue sarcoma of the extremities. Medicine (Baltimore). 2020 May 22;99(21):e20165 Authors: Li RH, Zhou Q, Li AB, Zhang HZ, Lin ZQ Abstract Soft tissue sarcoma (STS) of the extremities are a rare tumor. Metastases develop in about 40%-50% of patients, most of whom die from their disease. We sought to identify potential risk factors associated with metastatic diseases upon presentation...
Sat Jun 20, 2020 13:13
Related Articles Cutaneous metastasis of ascending colon cancer harboring a BRAF V600E mutation: A rare case report. Medicine (Baltimore). 2020 May 22;99(21):e20026 Authors: Liao L, Cheng Q, Zhu G, Pei F, Ye S Abstract RATIONALE: Cutaneous metastases from colorectal cancer are extremely rare and generally appear several years after diagnosis or resection of the primary colorectal tumor. Although cutaneous metastasis is unusual, it often indicates...
Sat Jun 20, 2020 13:13
Related Articles CD20+ tumor-infiltrating immune cells and CD204+ M2 macrophages are associated with prognosis in thymic carcinoma. Cancer Sci. 2020 Jun;111(6):1921-1932 Authors: Sato J, Kitano S, Motoi N, Ino Y, Yamamoto N, Watanabe S, Ohe Y, Hiraoka N Abstract Thymic carcinoma is a rare malignant disease with no standard systemic chemotherapy. The purpose of the present study was to investigate tumor-infiltrating immune cells (TIIC) in the...
Sat Jun 20, 2020 13:13
Related Articles Histopathology and immunohistochemistry as prognostic factors for poorly differentiated thyroid cancer in a series of Polish patients. PLoS One. 2020;15(2):e0229264 Authors: Walczyk A, Kopczyński J, Gąsior-Perczak D, Pałyga I, Kowalik A, Chrapek M, Hejnold M, Góźdź S, Kowalska A Abstract BACKGROUND: Poorly differentiated thyroid cancer (PDTC) is a rare but aggressive type of thyroid cancer (TC) and the main cause of death...
Sat Jun 20, 2020 13:13
Related Articles Laparoscopic ovarian drilling for ovulation induction in women with anovulatory polycystic ovary syndrome. Cochrane Database Syst Rev. 2020 02 11;2:CD001122 Authors: Bordewijk EM, Ng KYB, Rakic L, Mol BWJ, Brown J, Crawford TJ, van Wely M Abstract BACKGROUND: Polycystic ovary syndrome (PCOS) is a common condition affecting 8% to 13% of reproductive-aged women. In the past clomiphene citrate (CC) used to be the first-line treatment...
Sat Jun 20, 2020 13:13
Related Articles T-cell large granular lymphocytic (LGL) leukemia consists of CD4+/CD8dim and CD4-/CD8+ LGL populations in association with immune thrombocytopenia, autoimmune neutropenia, and monoclonal B-cell lymphocytosis. J Clin Exp Hematop. 2019;59(4):202-206 Authors: Kuwahara N, Kodaka T, Zushi Y, Sasaki M, Goka T, Maruoka H, Aoyama Y, Tsunemine H, Yamane T, Kobayashi J, Kawakami T, Ishida F, Itoh T, Takahashi T Abstract CD3+/CD57+ T-cell...
Sat Jun 20, 2020 13:13
Related Articles Gamma heavy chain disease (γ-HCD) as iatrogenic immunodeficiency- associated lymphoproliferative disorder: Possible emergent subtype of rheumatoid arthritis-associated γ-HCD. J Clin Exp Hematop. 2019;59(4):196-201 Authors: Tsunemine H, Zushi Y, Sasaki M, Nishikawa Y, Tamura A, Aoyama Y, Kodaka T, Itoh T, Takahashi T Abstract Gamma heavy chain disease (γ-HCD) is a rare B-cell neoplasm that produces a truncated immunoglobulin...
Sat Jun 20, 2020 13:13
Related Articles Image-guided intensity-modulated radiotherapy improves short-term survival for abdominal lymph node metastases from hepatocellular carcinoma. Ann Palliat Med. 2019 Nov;8(5):717-727 Authors: Zhang H, Chen Y, Hu Y, Yang P, Wang B, Zhang J, Sun J, Zeng Z Abstract BACKGROUND: Radiotherapy (RT) is an effective treatment for hepatocellular carcinoma (HCC) patients with lymph node metastasis (LNM), which is a rare clinical situation...
Sat Jun 20, 2020 13:13
Related Articles Navigation-Assisted Treatment of Giant Cysts in the Pterygopalatine Fossa With Endoscopy Method. J Craniofac Surg. 2020 Mar/Apr;31(2):e137-e139 Authors: Liu T, Sun Y, Li J, Bai W Abstract A couple of cysts lying in the pterygopalatine fossa are rare. The authors report a case of a 28-year-old woman who was admitted to the authors' hospital with a 1-month history of headache and numbness on the left head. Three-dimensional computed...
Sat Jun 20, 2020 13:13
Related Articles Patient-derived orthotopic xenograft models of sarcoma. Cancer Lett. 2020 01 28;469:332-339 Authors: Igarashi K, Kawaguchi K, Murakami T, Miyake K, Kiyuna T, Miyake M, Hiroshima Y, Higuchi T, Oshiro H, Nelson SD, Dry SM, Li Y, Yamamoto N, Hayashi K, Kimura H, Miwa S, Singh SR, Tsuchiya H, Hoffman RM Abstract Sarcoma is a rare and recalcitrant malignancy. Although immune and novel targeted therapies have been tested on many...
Sat Jun 20, 2020 13:13
Related Articles Osteosarcoma without prior retinoblastoma related to RB1 low-penetrance germline pathogenic variants: A novel type of RB1-related hereditary predisposition syndrome? Mol Genet Genomic Med. 2019 12;7(12):e913 Authors: Imbert-Bouteille M, Gauthier-Villars M, Leroux D, Meunier I, Aerts I, Lumbroso-Le Rouic L, Lejeune S, Delnatte C, Abadie C, Pujol P, Houdayer C, Corsini C Abstract BACKGROUND: Retinoblastoma (Rb) is a rare intraocular...
Sat Jun 20, 2020 13:13
Related Articles RAS and BRAF mutations in cell-free DNA are predictive for outcome of cetuximab monotherapy in patients with tissue-tested RAS wild-type advanced colorectal cancer. Mol Oncol. 2019 11;13(11):2361-2374 Authors: van Helden EJ, Angus L, Menke-van der Houven van Oordt CW, Heideman DAM, Boon E, van Es SC, Radema SA, van Herpen CML, de Groot DJA, de Vries EGE, Jansen MPHM, Sleijfer S, Verheul HMW Abstract In metastatic colorectal...
Sat Jun 20, 2020 13:13
Related Articles Biallelic germline BRCA1 mutations in a patient with early onset breast cancer, mild Fanconi anemia-like phenotype, and no chromosome fragility. Mol Genet Genomic Med. 2019 09;7(9):e863 Authors: Keupp K, Hampp S, Hübbel A, Maringa M, Kostezka S, Rhiem K, Waha A, Wappenschmidt B, Pujol R, Surrallés J, Schmutzler RK, Wiesmüller L, Hahnen E Abstract BACKGROUND: Biallelic BRCA1 mutations are regarded either embryonically lethal...
Sat Jun 20, 2020 13:13
Related Articles Fine needle aspiration diagnosis of metastatic Leydig cell tumor. Report of a case and review of the literature. J Am Soc Cytopathol. 2019 Jul - Aug;8(4):220-229 Authors: Biemer J, Pambuccian SE, Barkan GA Abstract Leydig cell tumors are rare sex cord-stromal tumors that account for less than 1% of all testicular tumors. Less than 10% of these tumors show metastatic malignant behavior. Herein we present a case of metastatic...
Sat Jun 20, 2020 13:13
Related Articles Primary Dedifferentiated Amelanotic Anorectal Melanoma: Report of a Rare Case. Int J Surg Pathol. 2019 Dec;27(8):923-928 Authors: Bell PD, Israel AK, Dunn AL, Liao X Abstract Anorectal melanoma (ARM) is an uncommon aggressive malignancy that comprises 0.5% to 1.6% of all melanoma manifestations. Dedifferentiated melanoma is very rare with loss of all melanocytic differentiation markers and is usually seen in metastatic melanoma...
Sat Jun 20, 2020 13:13
Related Articles Intrahepatic Carcinosarcoma With Cholangiocarcinoma Elements and Prominent Bile Duct Spread. Int J Surg Pathol. 2019 Dec;27(8):900-906 Authors: Usui G, Hashimoto H, Kusakabe M, Shirota G, Sugiura Y, Fujita Y, Satou S, Harihara Y, Horiuchi H, Morikawa T Abstract Carcinosarcomas with elements of cholangiocarcinoma and sarcoma are rare and have a poor prognosis. The spreading pattern and radiological findings of these lesions...
Sat Jun 20, 2020 13:13
Related Articles Serous Cystadenoma of the Pancreas With Complex Florid Papillary Architecture: A Case Report and Review of the Literature. Int J Surg Pathol. 2019 Dec;27(8):907-911 Authors: Tracht J, Reid MD, Hissong E, Sekhar A, Sarmiento J, Krasinskas A, Xue Y Abstract Serous cystadenoma (SCA) is a relatively rare benign pancreatic neoplasm. It has a very distinctive gross and microscopic appearance including pure and mixed microcystic and...
Sat Jun 20, 2020 13:13
Related Articles RPSAP52 lncRNA is overexpressed in pituitary tumors and promotes cell proliferation by acting as miRNA sponge for HMGA proteins. J Mol Med (Berl). 2019 07;97(7):1019-1032 Authors: D'Angelo D, Mussnich P, Sepe R, Raia M, Del Vecchio L, Cappabianca P, Pellecchia S, Petrosino S, Saggio S, Solari D, Fraggetta F, Fusco A Abstract Long non-coding RNAs (lncRNAs) are emerging as fundamental players in cancer biology. Indeed, they are...
Sat Jun 20, 2020 13:13
Related Articles Therapeutic uses of metronidazole and its side effects: an update. Eur Rev Med Pharmacol Sci. 2019 Jan;23(1):397-401 Authors: Hernández Ceruelos A, Romero-Quezada LC, Ruvalcaba Ledezma JC, López Contreras L Abstract OBJECTIVE: Metronidazole is an antibiotic widely used in different medical conditions such as trichomoniasis, amoebiasis, and giardiasis among others. Its use has been associated with toxicity; however, it is not...
Sat Jun 20, 2020 13:13
Related Articles Continued Endocrine Therapy Is Associated with Improved Survival in Patients with Breast Cancer Brain Metastases. Clin Cancer Res. 2019 05 01;25(9):2737-2744 Authors: Bergen ES, Berghoff AS, Medjedovic M, Rudas M, Fitzal F, Bago-Horvath Z, Dieckmann K, Mader RM, Exner R, Gnant M, Zielinski CC, Steger GG, Preusser M, Bartsch R Abstract PURPOSE: Brain metastases (BMs) are a rare but devastating condition in estrogen receptor...
Sat Jun 20, 2020 13:13
Related Articles Myasthenia Gravis and Thymoma Surgery: A Clinical Update for the Cardiothoracic Anesthesiologist. J Cardiothorac Vasc Anesth. 2019 Sep;33(9):2537-2545 Authors: Cata JP, Lasala JD, Williams W, Mena GE Abstract Myasthenia gravis (MG) is a rare neuromuscular disorder characterized by skeletal muscle weakness. Patients with MG who have thymoma and thymic hyperplasia have indications for thymectomy. The perioperative care of patients...
Sat Jun 20, 2020 13:13
Related Articles Approach to primary thyroid lymphoma: case series. Turk J Surg. 2019 Jun;35(2):142-145 Authors: Acar N, Acar T, Avcı A, Haciyanlı M Abstract Primary thyroid lymphomas are rare thyroid neoplasms. Mucosa Associated Lymphoid tissue (MALT) lymphoma and diffuse large B-cell Non-Hodgkin lymphoma are the most common types. It is more common in the elderly, and especially in women. Patients usually present with a rapidly growing mass...
Sat Jun 20, 2020 09:00
Related Articles Urothelial Papilloma of the Urinary Bladder in Children: Report of Two Cases. European J Pediatr Surg Rep. 2020 Jan;8(1):e23-e26 Authors: Davidovics K, Davidovics S, Farkas A, Benedek N, Tornoczki T, Kardos D, Davidovics A, Vajda P Abstract Urothelial neoplasms of the bladder (UNB) are considerably rare throughout the pediatric population. UNB develops from the urothelial tissue in the form of a benign disease, generally favoring...
Sat Jun 20, 2020 09:00
Related Articles Tumor Lysis Syndrome Caused by Unrecognized Richter's Transformation of Chronic Lymphocytic Leukemia: Treatment With Venetoclax for Suspected Disease Progression. Cureus. 2020 May 15;12(5):e8145 Authors: Chango Azanza JJ, Calle Sarmiento PM, Mathew Thomas V, Lopetegui Lia N, Kidwai N Abstract Richter's transformation (RT) is defined as the transition of chronic lymphocytic leukemia (CLL) or small lymphocytic leukemia (SLL) into...
Sat Jun 20, 2020 09:00
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