Abstract Purpose The flexor digitorum superficialis muscle (FDS) is considered the most important of the forearm flexors for maintaining elbow valgus stability. However, the relationships between the origin structure of each finger of the FDS and the anterior oblique ligament (AOL) of the ulnar collateral ligament and the common tendon (CT) in the proximal part, and morphological features are unclear. The purpose of this study was to...
Sat Jun 20, 2020 03:00
Pre- and post-partum depression is a common mood disorder with detrimental effects on both mother and child. The aim of the proposed review is to summarize evidence related to the effects of both pre- and post...
Fri Jun 19, 2020 03:00
Facial asymmetry secondary to unilateral condylar hyperplasia can be a diagnostic challenge to oral and maxillofacial surgeons. Single positron emission computed tomography (SPECT) scans provide a useful adjunct. We report a brief summary of the evidence describing the effectiveness of different methods of analysing SPECT scans and compare it with the results of a 10-year study at Sunderland Royal Hospital. Overall, both the evidence base and our study strongly favour use of the condyle:condyle ratio...
Sat Jun 20, 2020 03:00
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Sat Jun 20, 2020 03:00
Specialist registration in oral and maxillofacial surgery (OMFS) requires dual medical and dental qualification involving at least eight years of undergraduate study. Training has continued to evolve since dual qualification was introduced and has often resulted in unwarranted repetition. If a time-based curriculum is necessary, second degree trainees should be allowed to pursue research and audit, and gain relevant clinical experience in lieu of repeating previously covered material. Junior surgical...
Sat Jun 20, 2020 03:00
The COVID-19 pandemic has thrust not only a novel virus onto the world, but new challenges resulting in novel approaches. Governments have reduced regulation in order to facilitate timely advances to combat the disease. Antibody testing has rapidly been deployed but it is creating challenges for staff and patients. Mask use has come to the forefront and human factor (HF) strategies must be examined to reduce risk associated with lack of engagement from both healthcare staff and patients. In this...
Sat Jun 20, 2020 03:00
The COVID-19 crisis has caused many issues across healthcare. In surgery, many operations have been cancelled with some surgeons losing their regular operating lists. During this time, technical expertise and decision making can deteriorate. In aviation after a prolonged period of absence from flying, this deficit in keeping skills and thinking up to date is known as being “out of currency” or “not current”. Although aviation and healthcare cannot be compared, numerous human factors concepts are...
Fri Jun 19, 2020 03:00
Abstract Background and aim A close relationship between adiposity and increased cortisol levels is well established in patients with endogenous hypercortisolism. Nevertheless, hypothalamic-pituitary-adrenal (HPA) axis regulation in overweight subjects is still a matter of concern. We studied free cortisol (urinary free cortisol, UFC and late night salivary cortisol, LNSC), pituitary feedback (serum cortisol after 1 mg dexamethasone...
Sat Jun 20, 2020 03:00
Abstract Objective Whether breastfeeding influences thyroid function and autoimmunity is not elucidated. We examined the association of history of breastfeeding with thyroid hormones and thyroperoxidase antibody (TPOAb). Design Cross-sectional study of data from the 2013–2015 Korea National Health and Nutrition Examination Survey. ...
Fri Jun 19, 2020 03:00
Abstract Background Both thyroid-stimulating immunoglobulins immunoassay (TSI IA) and thyrotrophin receptor antibody immunoassay (TRAb IA) are commonly used for the diagnosis of Graves’ disease (GD). The aim of the present study was to compare the clinical diagnostic performance of these two methods. Methods Sera were obtained from 1103 subjects presenting...
Fri Jun 19, 2020 03:00
Abstract Purpose Pituitary diseases severely affect patients’ health-related quality of life (HRQoL). The most frequently used generic HRQoL questionnaire is the Short Form-36 (SF-36). The shorter 12-item version (SF-12) can improve efficiency of patient monitoring. This study aimed to determine whether SF-12 can replace SF-36 in pituitary care. Methods ...
Fri Jun 19, 2020 03:00
Abstract Purpose Obstructive sleep apnea (OSA) is associated with obesity and risk for type 2 diabetes. In this community-based study, we thoroughly investigated fatty acid metabolism, incretin response, glucose tolerance, insulin secretion and insulin sensitivity, and autonomic nerve activity in men with or without OSA. Methods Fifteen men without...
Fri Jun 19, 2020 03:00
Abstract Purpose Acromegaly is a rare disease due to growth hormone (GH)-secreting pituitary adenoma. GH and IGF-1 levels are usually congruent, indicating either remission or active disease; however, a discrepancy between GH and IGF-1 may occur. We aimed to evaluate the outcome of diabetes mellitus (DM) and hypertension (HT) in acromegalic patients with congruent GH and/or IGF-1 levels vs. discordant biochemical parameters. ...
Fri Jun 19, 2020 03:00
The overall goal of the protocol is to prepare over one million ordered, uniform, stable, and biocompatible femtoliter droplets on a 1 cm2 planar substrate that can be used for cell-free protein synthesis.
Sat Jun 20, 2020 20:30
We present a protocol to use a computational tool to record and analyze the functional abilities of children aged 3-6 years old. The protocol facilitates the comparison of these abilities throughout their development and can be used to assess developmental difficulties.
Sat Jun 20, 2020 19:31
Related Articles The Importance of Left Atrial Function after Myocardial Infarction. Radiology. 2020 Jun 16;:202132 Authors: Kawel-Boehm N, Bremerich J PMID: 32552514 [PubMed - as supplied by publisher]
Sat Jun 20, 2020 16:32
Related Articles Effects of Carbonation and Temperature on Voluntary Swallowing in Healthy Humans. Dysphagia. 2020 Jun 16;: Authors: Takeuchi C, Takei E, Ito K, Kulvanich S, Magara J, Tsujimura T, Inoue M Abstract We investigated how swallowing behaviors are affected by the temperature and carbonation of water in healthy humans. Twenty-nine healthy volunteers were instructed to drink as much natural water, carbonated water, or cider as they...
Sat Jun 20, 2020 16:27
Related Articles Potential for Volitional Control of Resting Pressure at the Upper Oesophageal Sphincter in Healthy Individuals. Dysphagia. 2020 Jun 18;: Authors: Winiker K, Gozdzikowska K, Guiu Hernandez E, Kwong SL, Macrae P, Huckabee ML Abstract Resting pressure at the upper oesophageal sphincter (UOS) has been reported to be susceptible to factors such as emotional stress or respiration. This exploratory study investigated the potential...
Sat Jun 20, 2020 16:27
Related Articles Shedding Light on Dysphagia Associated With COVID-19: The What and Why. OTO Open. 2020 Apr-Jun;4(2):2473974X20934770 Authors: Mohan R, Mohapatra B Abstract The most common symptom of COVID-19 in critically ill patients is ARDS (acute respiratory distress syndrome), with many patients requiring invasive or noninvasive respiratory support in the intensive care unit. Oropharyngeal dysphagia may be a consequence of the respiratory-swallowing...
Sat Jun 20, 2020 16:27
Publication date: Available online 19 June 2020Source: European Journal of Vascular and Endovascular SurgeryAuthor(s): Luca Bertoglio, Roberto Chiesa
Sat Jun 20, 2020 16:22
Publication date: Available online 19 June 2020Source: European Journal of Vascular and Endovascular SurgeryAuthor(s): Bijit Munshi, Barry J. Doyle, Jens C. Ritter, Shirley Jansen, Louis P. Parker, Vincent Riambau, Colin Bicknell, Paul E. Norman, Anders Wanhainen
Sat Jun 20, 2020 16:22
Publication date: Available online 19 June 2020Source: European Journal of Vascular and Endovascular SurgeryAuthor(s): Oliver Lyons
Fri Jun 19, 2020 15:22
Improving the predication efficiency of porcine production performance at early stage will contribute to reducing the breeding and production costs. The intestinal microbiota had received plenty of attention i...
Fri Jun 19, 2020 03:00
A bovine colostrum fraction (BCF) was recently shown to enhance the adherence of several commensal organisms to intestinal epithelial cells through modulating the epithelial cell surface. In this study, the ma...
Thu Jun 18, 2020 03:00
Publication date: Available online 19 June 2020Source: International Journal of Oral and Maxillofacial SurgeryAuthor(s): Andrew Heggie
Sat Jun 20, 2020 15:36
Due to limited therapeutic options and their association with high mortality and morbidity, carbapenem-non-susceptible Acinetobacter spp. (CNA) are of significant public health importance. This study aimed to des...
Fri Jun 19, 2020 03:00
Abstract A 23.4-week premature and extremely low birth weight neonate was transferred to the Neonatal Intensive Care Unit for management of respiratory failure and retrocardiac pneumomediastinum, suspected to be the result of a low tracheal injury during intubation. Initial conservative management failed and chest radiographs demonstrated worsening retrocardiac pneumomediastinum. Due to the patient’s extreme low birth weight and location of the pneumomediastinum, surgery was deemed...
Sat Jun 20, 2020 03:00
Related Articles Into and out of the cochlea: A re-implantation saga. Cochlear Implants Int. 2020 Jun 18;:1-5 Authors: Wendell Todd N, Fainberg JC, Kadom N Abstract Introduction: In patients with normal inner ear architecture at imaging and who received a prior cochlear implant (CI) without difficulty, the expectation is that replacing a failed CI should be straightforward. Here, we present a patient in whom an unusual complication (to...
Sat Jun 20, 2020 14:31
Abstract Rationale The nuclear receptor retinoid X receptor (RXR) belongs to a nuclear receptor superfamily that modulates diverse functions via homodimerization with itself or several other nuclear receptors, including PPARα. While the activation of PPARα by natural or synthetic agonists regulates the sleep-wake cycle, the role of RXR in the sleep modulation is unknown. ...
Sat Jun 20, 2020 14:18
Abstract Rationale Effort-based decision-making tasks allow animals to choose between preferred reinforcers that require high effort to obtain vs. low-effort/low reward options. Mesolimbic dopamine (DA) and related neural systems regulate effort-based choice. Tetrabenazine (TBZ) is a vesicular monoamine transport type-2 inhibitor that blocks DA storage and depletes DA. In humans, TBZ induces motivational dysfunction and depression. TBZ...
Fri Jun 19, 2020 03:00
Abstract To take full advantage of recombinant Pichia pastoris (Komagataella phaffii) as a production system for heterologous proteins, the complex protein secretory process should be understood and optimised by circumventing bottlenecks. Typically, little or no attention has been paid to the fate of newly synthesised protein inside the cell, or its passage through the secretory pathway, and only the secreted product is measured. However, the system’s productivity (i.e. specific...
Sat Jun 20, 2020 14:07
Abstract Due to a high unresponsiveness to chemotherapy, biofilm formation is an important medical problem that frequently occurs during infection with many bacterial pathogens. In this study, the marine sponge-derived natural compounds 4,6-dibromo-2-(2′,4′-dibromophenoxy)phenol and 3,4,6-tribromo-2-(2′,4′-dibromophenoxy)phenol were found to exhibit broad antibacterial activity against medically relevant gram-positive and gram-negative pathogens. The...
Sat Jun 20, 2020 14:07
Abstract The objective of this study was to evaluate the effect of undernutrition on colonic microbiota and fermentation in pregnant ewes. Sixteen ewes bearing multiple fetuses for 115 days in the control (CON) and severe feed restriction (SFR) groups were fed 100% and 30% level of ad libitum feed intake, respectively. After 15-day treatment, all ewes were sacrificed to collect colonic digesta samples to extract DNA for 16S rRNA sequencing and to detect...
Sat Jun 20, 2020 14:07
Abstract Deoxynivalenol (DON) is commonly found in wheat and wheat-derived foods, posing a threat to human health. Biodegradation is an efficient and eco-friendly measure for mycotoxin detoxification. Understanding the mechanism of DON biodegradation is hence of great importance. Herein, we report the application of metabolomics methods for the analysis of DON degradation by a bacterial consortium isolated from wheat leaves collected in Jiangsu Province. Metabolomics analysis...
Sat Jun 20, 2020 14:07
Abstract Basidioma is the fruiting body of mushroom species. The deep understanding on the mechanism of basidioma development is valuable for mushroom breeding and cultivation. From winter mushroom (Flammulina velutipes), one of the top five industrially cultivated mushrooms, a novel putative Zn(II)2Cys6 transcription factor LFC1 with negative regulatory function in basidioma development was identified. The transcript level of lfc1 was dramatically decreased during basidioma...
Sat Jun 20, 2020 14:07
Abstract The ability to synthesize particular steviol glycosides (SvGls) was studied in Stevia rebaudiana Bertoni hairy roots (HR) grown in the light or in the dark under the influence of different osmotic active compounds. Manipulation of culture conditions led to changes in the morphology and growth rate of HR, as well as to an increase in oxidative stress manifested as an enhancement in endogenous hydrogen peroxide concentration in the cultured samples. The highest level...
Sat Jun 20, 2020 14:07
Abstract Aerobic granular sludge (AGS) is a microbial biofilm self-aggregation, which is effective for nutrient and pollutant removal, through the development of dense microbial layers bound together with extracellular polymeric substances (EPSs). However, long start-up times and granule disintegration are still challenges ahead. An array of external additives, including ion chelating agents, sludge-based enhancers, and magnetic influence have been...
Sat Jun 20, 2020 14:07
Abstract Oleate hydratases (Ohys, EC 4.2.1.53) are a class of enzymes capable of selective water addition reactions to a broad range of unsaturated fatty acids leading to the respective chiral alcohols. Much research was dedicated to improving the applications of existing Ohys as well as to the identification of undescribed Ohys with potentially novel properties. This study focuses on the latter by exploring the genus Rhodococcus for its plenitude of oleate hydratases. Three...
Sat Jun 20, 2020 14:07
Related Articles In Memoriam: James Tait Goodrich. J Neurosurg Pediatr. 2020 Jun 19;:1-2 Authors: Abbott R PMID: 32559742 [PubMed - as supplied by publisher]
Sat Jun 20, 2020 17:43
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