Related Articles Role of Olfaction in Human Health: A Focus on Coronaviruses. Allergy Rhinol (Providence). 2020 Jan-Dec;11:2152656720928245 Authors: Jaime-Lara RB, Parma V, Yan CH, Faraji F, Joseph PV PMID: 32551179 [PubMed]
Sat Jun 20, 2020 13:10
Related Articles Rapid Validation of Telepathology by an Academic Neuropathology Practice During the COVID-19 Pandemic. Arch Pathol Lab Med. 2020 Jun 18;: Authors: Henriksen J, Kolognizak T, Houghton T, Cherne S, Zhen D, Cimino PJ, Latimer CS, Scherpelz KP, Yoda RA, Alpers CE, Chhieng DF, Dirk Keene C, Gonzalez-Cuyar LF Abstract CONTEXT: The coronavirus disease 19 (COVID-19) pandemic is placing unparalleled burdens on regional and institutional...
Sat Jun 20, 2020 17:55
Related Articles Coagulation dysfunction: A hallmark in COVID-19. Arch Pathol Lab Med. 2020 Jun 18;: Authors: Fei Y, Tang N, Liu H, Cao W Abstract Context: The coronavirus disease 2019 (COVID-19) is a highly contagious respiratory disease caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Coagulation dysfunction is a hallmark in patients with COVID-19. Fulminant thrombotic complications emerge as critical issues in patients...
Sat Jun 20, 2020 17:55
Related Articles Third-line sunitinib treatment in a VHL-mutated metastatic intrahepatic cholangiocarcinoma: a case report and literature review. Cancer Biol Ther. 2020 Jun 18;:1-5 Authors: Li X, Gao L, Zhang L, Sun H, Gou H Abstract Intrahepatic cholangiocarcinoma (iCCA) is a highly aggressive malignancy with a poor prognosis. There is no standard treatment beyond first-line chemotherapy and no molecular-targeted drug approved for advanced...
Sat Jun 20, 2020 18:04
Related Articles Angiopoietin-1 is associated with a decreased risk of lymph node metastasis in early stage cervical cancer. Histol Histopathol. 2020 Jun 17;:18234 Authors: Cai E, Yang D, Zhang Y, Cai J, Sun S, Yang P, Huang Y, Han Q, Xiong Z, Wang S Abstract OBJECTIVES: Lymph node metastasis (LNM) is an important determinant of prognosis in patients with cervical cancer. Members of the angiopoietin family have been demonstrated to regulate...
Sat Jun 20, 2020 18:38
Related Articles Phosphorylated TDP-43 localizes to chronic cerebral infarctions in human brains. Histol Histopathol. 2020 Jun 18;:18235 Authors: Umahara T, Uchihara T, Hirao K, Shimizu S, Hanyu H Abstract The transactivation response DNA-binding protein of 43 kDa (TDP-43) is a nuclear protein pivotal in RNA processing. Because phosphorylated TDP43 (pTDP-43) has been identified as a component of the ubiquitin-positive and tau-negative inclusions...
Sat Jun 20, 2020 18:38
Related Articles Spontaneous Skull Base Cerebrospinal Fluid Leaks and Their Relationship to Idiopathic Intracranial Hypertension. Am J Rhinol Allergy. 2020 Jun 19;:1945892420932490 Authors: Bidot S, Levy JM, Saindane AM, Narayana KM, Dattilo M, DelGaudio JM, Mattox DE, Oyesiku NM, Peragallo JH, Solares CA, Vivas EX, Wise SK, Newman NJ, Biousse V Abstract BACKGROUND: The association between spontaneous skull base cerebrospinal fluid (CSF) leaks...
Sat Jun 20, 2020 19:44
Related Articles An Exploratory Study on the Use of Event-Related Potentials as an Objective Measure of Auditory Processing and Therapy Effect in Patients With Tinnitus: A Transcranial Direct Current Stimulation Study. Otol Neurotol. 2019 10;40(9):e868-e875 Authors: Jacquemin L, Mertens G, Van de Heyning P, Vanderveken OM, Topsakal V, De Hertogh W, Michiels S, Beyers J, Moyaert J, Van Rompaey V, Gilles A Abstract OBJECTIVE: Treatment effect...
Sat Jun 20, 2020 14:00
Related Articles An Emerging Therapeutic Approach by Targeting Myoferlin (MYOF) for Malignant Tumors. Curr Top Med Chem. 2020 Jun 18;: Authors: Gu H, Peng Y, Chen Y Abstract Myoferlin (MYOF), as a member of the ferlin family, is a type II transmembrane protein with a single transmembrane domain at the carbon terminus. Studies have shown that MYOF is involved in pivotal physiological functions related to numerous cell membranes, such as extracellular...
Sat Jun 20, 2020 15:33
Related Articles Identification of potential inhibitors for targets involved in Dengue fever. Curr Top Med Chem. 2020 Jun 18;: Authors: Shanmugam A, Ramakrishnan C, Velmurugan D, Gromiha MM Abstract Lethality due to dengue infection is a global threat. Nearly 400 million people are affected every year, which approximately costs 500 million dollar for surveillance and vector control itself. Many investigations on structure-function relationship...
Sat Jun 20, 2020 15:33
Related Articles Synthesis, Antimicrobial, Antioxidant and Molecular Docking Studies on Novel 6-Methoxybenzothiazole-piperazine Derivatives with Propanamide Chain. Curr Top Med Chem. 2020 Jun 18;: Authors: Alhusadi NA, Turgutalp B, Deniz I, Acar ET, Sipahi H, Yarim M, Gurdal EE Abstract BACKGROUND: Infectious diseases are a major threat in the developing world and the discovery of novel antimicrobial agents remain to be crucial due to acquired...
Sat Jun 20, 2020 15:33
Related Articles Quinoline-based compounds with potential activity against drug-resistant cancers. Curr Top Med Chem. 2020 Jun 18;: Authors: Li HT, Zhu X Abstract Drug resistance is the major cause of the failure of cancer chemotherapy, so one of the most important features in developing effective cancer therapeutic strategies is to overcome drug resistance. Quinoline moiety has become one of the most privileged structural motifs in anticancer...
Sat Jun 20, 2020 15:33
Related Articles Evidence Linking Protein Misfolding to Quality Control in Progressive Neurodegenerative Diseases. Curr Top Med Chem. 2020 Jun 18;: Authors: Kabir MT, Uddin MS, Abdeen A, Ashraf GM, Perveen A, Hafeez A, Bin-Jumah MN, Abdel-Daim MM Abstract Several proteolytic systems including ubiquitin (Ub)-proteasome system (UPS), chaperone-mediated autophagy (CMA), and macroautophagy are used by the mammalian cells to remove misfolded proteins...
Sat Jun 20, 2020 15:33
Related Articles Current insights into interethnic variability in testicular cancers: Population pharmacogenetics, clinical trials, genetic basis of chemotherapy-induced toxicities and molecular signal transduction. Curr Top Med Chem. 2020 Jun 18;: Authors: Vasistha A, Kothari R, Mishra A, De Andrés F, LLerena A, Nair S Abstract Testicular cancer is an aggressive malignancy with a rising incidence rate across the globe. Testicular germ cell...
Sat Jun 20, 2020 15:33
Related Articles Predictors of Voice Therapy Initiation: A Cross-Sectional Cohort Study. J Voice. 2020 Jun 16;: Authors: Pasternak K, Diaz J, Thibeault SL Abstract OBJECTIVES/HYPOTHESIS: To determine predictors of voice therapy initiation. STUDY DESIGN: Cross-sectional cohort study. METHODS: All patients were evaluated in an interdisciplinary model at the University of Wisconsin Voice and Swallow Clinics between June 2016 and...
Sun Jun 21, 2020 13:36
Related Articles Regenerative Efficacy of Fibroblast Growth Factor for the Treatment of Aged Vocal Fold: From Animal Model to Clinical Application. Clin Otolaryngol. 2020 Jun 18;: Authors: Ban MJ, Lee SC, Park JH, Park KN, Kim HK, Lee SW Abstract OBJECTIVES: We assessed fibroblast growth factor (FGF) regenerative efficacy in an aged vocal fold rat model and confirmed it in a prospective clinical trial. DESIGN, SETTING, AND PARTICIPANTS:...
Sat Jun 20, 2020 17:38
Related Articles Epidermoid cyst abscess of the neck masquerading as a thyroid abscess. Endocrinol Diabetes Metab Case Rep. 2020 Jun 04;2020: Authors: Chatchomchaun W, Thewjitcharoen Y, Krittadhee K, Veerasomboonsin V, Nakasatien S, Krittiyawong S, Porramatikul S, Wanathayanoroj E, Kanchanapituk A, Junyangdikul P, Himathongkam T Abstract Summary: In this case report, we describe a 37-year-old male who presented with fever and tender neck mass....
Sat Jun 20, 2020 17:38
Related Articles Patient Experience Contributing to Outcomes of Laryngeal Botulinum Toxin Injection. J Voice. 2020 Jun 15;: Authors: Rutt A, Kennelly KD, Martinez-Paredes JF Abstract OBJECTIVES: Laryngeal Botulinum Toxin injection (LBTX) in the adductor musculature is the current therapy for Adductor Spasmodic Dysphonia. This study explores nonbiological factors that can affect the patient experience during this procedure and their association...
Sat Jun 20, 2020 17:38
Related Articles Voiced High-Frequency Oscillation or Lax Vox Technique? Immediate Effects in Dysphonic Individuals. J Voice. 2020 Jun 14;: Authors: Silva R, Antonetti ADS, Ribeiro VV, Ramos AC, Brasolotto AG, Silverio KCA Abstract OBJECTIVES: To analyze the immediate effects of voiced high-frequency oscillation (VHFO) and Lax Vox technique on vocal quality and self-reported intensity of vocal and laryngeal symptoms in individuals with behavioral...
Sat Jun 20, 2020 17:38
Related Articles Life Threatening Delayed Complication of Botulinum Toxin Injection for Treatment of Spasmodic Dysphonia. Prague Med Rep. 2020;121(2):114-117 Authors: Yershov D, Partridge R Abstract Spasmodic dysphonia is a primary task specific focal dystonia affecting the laryngeal muscles during speech. Most medical and surgical approaches to treatment of spasmodic dysphonia are aimed at the denervation of the laryngeal muscles to block symptom...
Sat Jun 20, 2020 17:38
Related Articles Validation of the Spanish Version of the STOP-Bang Questionnaire: Usefulness as a Screening Tool for Obstructive Sleep Apnea in Adults. Ear Nose Throat J. 2020 Jun 18;:145561320932334 Authors: Delgado-Vargas B, Acle-Cervera L, Narciso López G Abstract OBJECTIVES: Obstructive sleep apnea syndrome (OSAS) is an increasing health problem, the diagnosis of which is generally delayed due to long waiting lists for the tests used...
Sat Jun 20, 2020 17:32
Related Articles Hypopharyngeal and Laryngeal Lesions in a Patient with Chickenpox. Ear Nose Throat J. 2020 Jun 18;:145561320932312 Authors: Hsu PY, Jang TY PMID: 32551963 [PubMed - as supplied by publisher]
Sat Jun 20, 2020 17:32
Related Articles Tympanostomy Tubes-A Visual Guide for the Young Otolaryngologist. Ear Nose Throat J. 2020 Jun 18;:145561320929885 Authors: Isaacson G Abstract OBJECTIVES: To illustrate some of the common dilemmas in tympanostomy tube care and describe time-tested ways to address them. METHODS: Computerized literature review. RESULTS: Issues including the correct diagnosis of recurrent acute otitis media, tympanostomy...
Sat Jun 20, 2020 17:32
Related Articles Temperature Measurements of the Semicircular Canal During Green Laser Irradiation of the Canal: A Preliminary Study. Ear Nose Throat J. 2020 Jun 18;:145561320932794 Authors: Nogaki T, Nomura Y, Shimatani Y, Kobayashi H Abstract BACKGROUND: Laser irradiation of the semicircular canal (SCC) is a good treatment for intractable benign paroxysmal positional vertigo. However, there were few reports on the temperature changes...
Sat Jun 20, 2020 17:32
Related Articles Outcome of Balloon Eustachian Tuboplasty in SCUBA Divers. Ear Nose Throat J. 2020 Jun 18;:145561320933957 Authors: Ungar OJ, Cavel O, Yahav O, Tsur N, Handzel O Abstract OBJECTIVES: Good Eustachian tube (ET) function is necessary in order to equalize middle ear (ME) pressure with ambient pressures and avoid barotrauma among divers. Since placement of ventilation tubes is not compatible with diving, balloon eustachian tuboplasty...
Sat Jun 20, 2020 17:32
Related Articles Isolated Congenital Supernumerary Nostril in an Adult Patient. Ear Nose Throat J. 2020 Jun 18;:145561320933390 Authors: Alqabbani AA, Alateeq MF, Alshalaan Z Abstract The supernumerary nostril is a congenital accessory nostril, which is considered to be one of the rarest congenital nasal anomalies with an unknown etiology. We present the first case of a supernumerary nostril in an adult Saudi patient, which is the first...
Sat Jun 20, 2020 17:32
Related Articles Application of Enhanced Recovery After Surgery in Perioperative Period of Tympanoplasty and Mastoidectomy. Ear Nose Throat J. 2020 Jun 18;:145561320928222 Authors: Tan JQ, Chen YB, Wang WH, Zhou SL, Zhou QL, Li P Abstract INTRODUCTION: Enhanced recovery after surgery (ERAS) protocols are a series of perioperative care to optimize preoperative preparation, prevent postoperative complications, minimize stress, and speedup...
Sat Jun 20, 2020 17:32
Related Articles Endoscopy-Aided Combined Intraoral and Cervical Approach for a Huge Parapharyngeal Benign Tumor. Ear Nose Throat J. 2020 Jun 18;:145561320935834 Authors: Tsunoda A, Kishimoto S, Tou M, Anzai T, Matsumoto F, Oba S, Ikeda K Abstract We introduce here our surgical approach for the removal of a huge parapharyngeal tumor in 3 cases. Surgery was done under general anesthesia using transnasal intubation. Transoral manipulation...
Sat Jun 20, 2020 17:32
Related Articles Erratum: Therapeutic effect of vascular interventional therapy andaspirin combined with defibrase on cerebral ischemia in rats. Exp Ther Med. 2020 Jul;20(1):678 Authors: Li B, Geng S, Da Y Abstract [This corrects the article DOI: 10.3892/etm.2018.6271.]. PMID: 32550889 [PubMed - in process]
Sat Jun 20, 2020 13:02
Related Articles N,N-diethylaminobenzaldehyde targets aldehyde dehydrogenase to eradicate human pancreatic cancer cells. Exp Ther Med. 2020 Jul;20(1):662-670 Authors: Wang W, Zheng S, He H, Ge H, Saeed BR Abstract Pancreatic cancer is a common cause of worldwide cancer-related mortality with a poor 5-year survival rate. Aldehyde dehydrogenase (ALDH) activity is a possible marker for malignant stem cells in solid organ systems, including the...
Sat Jun 20, 2020 13:02
Related Articles Inhibition of acetyl-CoA carboxylase by PP-7a exerts beneficial effects on metabolic dysregulation in a mouse model of diet-induced obesity. Exp Ther Med. 2020 Jul;20(1):521-529 Authors: Liu T, Gou L, Yan S, Huang T Abstract Acetyl-coenzyme A carboxylase (ACC) is a critical regulator of fatty acid metabolism and represents a promising therapeutic target for metabolic diseases, including obesity, type 2 diabetes and non-alcoholic...
Sat Jun 20, 2020 13:02
Related Articles Baicalin serves a protective role in diabetic nephropathy through preventing high glucose-induced podocyte apoptosis. Exp Ther Med. 2020 Jul;20(1):367-374 Authors: Li J, Ling Y, Yin S, Yang S, Kong M, Li Z Abstract Diabetic nephropathy (DN) is one of the late complications of diabetes, which seriously affects the lives of patients. Baicalin (BA) is a flavone glycoside that has been identified to improve renal function in patients...
Sat Jun 20, 2020 13:02
Related Articles Raloxifene improves TNF-α-induced osteogenic differentiation inhibition of bone marrow mesenchymal stem cells and alleviates osteoporosis. Exp Ther Med. 2020 Jul;20(1):309-314 Authors: Yang F, Jia Y, Sun Q, Zheng C, Liu C, Wang W, Du L, Kang S, Niu X, Li J Abstract Effect of raloxifene (RLF) on the improvement of inhibited osteogenic differentiation of bone marrow mesenchymal stem cells (BMSCs) resulted from tumor necrosis factor-α...
Sat Jun 20, 2020 13:02
Related Articles Effects of icariin on cell injury and glucocorticoid resistance in BEAS-2B cells exposed to cigarette smoke extract. Exp Ther Med. 2020 Jul;20(1):283-292 Authors: Hu L, Liu F, Li L, Zhang L, Yan C, Li Q, Qiu J, Dong J, Sun J, Zhang H Abstract Glucocorticoids (GCs) exert a therapeutic effect in numerous chronic inflammatory diseases. However, chronic obstructive pulmonary disease (COPD) tends to be GC-resistant. Icariin, a major...
Sat Jun 20, 2020 13:02
Related Articles Platelet count is closely associated with the severity of liver injury in patients with chronic hepatitis B virus infection: A cross-sectional study. Exp Ther Med. 2020 Jul;20(1):243-250 Authors: Yang YT, Wang LL, Yan LT, Zhang LT, Zhou W, Chen QF, Chen Y, Zheng SJ, Duan ZP, Li JF Abstract Although the platelet count may provide clues regarding the severity of liver disease, there are currently no available data supporting the...
Sat Jun 20, 2020 13:02
Related Articles The increasing impact of Chinese innovative drug research on the global stage with a focus on drug discovery. Expert Opin Drug Discov. 2020 Jun 17;:1-6 Authors: Luo W, Srinivasulu C, Hao X, Liu X, Zhan P PMID: 32552058 [PubMed - as supplied by publisher]
Sat Jun 20, 2020 15:16
Related Articles The application of machine learning techniques to innovative antibacterial discovery and development. Expert Opin Drug Discov. 2020 Jun 17;:1-15 Authors: Serafim MSM, Kronenberger T, Oliveira PR, Poso A, Honório KM, Mota BEF, Maltarollo VG Abstract INTRODUCTION: After the initial wave of antibiotic discovery, few novel classes of antibiotics have emerged, with the latest dating back to the 1980's. Furthermore, the pace of antibiotic...
Sat Jun 20, 2020 15:16
Related Articles The chemical probe - scopes, limitations and challenges. Expert Opin Drug Discov. 2020 Jun 19;:1-3 Authors: Stark H Abstract Drug design needs high-quality chemical probes for target validation, but the demands on chemical probes are largely different than those on drugs. Whereas therapeutic value and safety are main criteria for a drug evaluation, the chemical probe is influencing a biological target in a well-characterized...
Sat Jun 20, 2020 15:16
Related Articles [Unilateral diseases of the maxillary sinus]. HNO. 2020 Jun 17;: Authors: Giotakis E, Knipping S, Kühnel T, Weber RK Abstract Unilateral diseases of the maxillary sinus are among the most common rhinologic diagnoses. The diversity of these diseases can represent a challenge for the treating physician. The spectrum ranges from harmless maxillary sinus cysts that seldom require treatment, to highly aggressive malignant tumors....
Sat Jun 20, 2020 17:35
Related Articles [Erratum to: Recognition function for the Freiburg monosyllabic test in noise with a signal to noise ratio (SNR) of 5dB]. HNO. 2020 Jun 17;: Authors: Guy S, Schönweiler R, Wollenberg B, Zehlicke T, Pohl M, Löhler J PMID: 32556467 [PubMed - as supplied by publisher]
Sat Jun 20, 2020 17:35
Related Articles Efficacy and safety of HIF prolyl-hydroxylase inhibitor vs epoetin and darbepoetin for anemia in chronic kidney disease patients not undergoing dialysis: a network meta-analysis. Pharmacol Res. 2020 Jun 16;:105020 Authors: Zheng Q, Yang H, Sun L, Wei R, Fu X, Wang Y, Huang Y, Liu YN, Liu WJ Abstract Hypoxia-inducible factor prolyl hydroxylase inhibitors (HIF-PHIs) are a new class of oral medicines being developed for the treatment...
Sun Jun 21, 2020 14:28
Related Articles Perinatal Hypoxia-Inducible Factor Stabilization Preserves Lung Alveolar and Vascular Growth in Experimental BPD. Am J Respir Crit Care Med. 2020 Jun 18;: Authors: Hirsch K, Taglauer E, Seedorf G, Callahan C, Mandell E, White CW, Kourembanas S, Abman SH Abstract BACKGROUND: Antenatal inflammation with placental dysfunction is strongly associated with high BPD risk in preterm infants. Whether antenatal or postnatal HIF augmentation...
Sat Jun 20, 2020 14:21
Association between Toxoplasma gondii infection and headache: a systematic review and meta-analysis.
Related Articles Association between Toxoplasma gondii infection and headache: a systematic review and meta-analysis. Infect Disord Drug Targets. 2020 Jun 17;: Authors: Nayeri T, Sarvi S, Moosazadeh M, Hosseininejad Z, Amouei A, Daryani A Abstract BACKGROUND: The impact of infectious agents, such as Toxoplasma gondii (T. gondii), on human behavior and mental disorders has recently attracted the attention of researchers. T. gondii has emerged...
Sat Jun 20, 2020 15:20
Related Articles Measuring the effectiveness of an automated text messaging active surveillance system for COVID-19 in the south of Ireland, March to April 2020. Euro Surveill. 2020 Jun;25(23): Authors: Barrett PM, Bambury N, Kelly L, Condon R, Crompton J, Sheahan A, regional Department of Public Health Abstract We report the effectiveness of automated text messaging for active surveillance of asymptomatic close contacts of coronavirus disease...
Sat Jun 20, 2020 16:45
Related Articles Letter to the editor: Wide indication for SARS-CoV-2-testing allowed identification of international risk areas during the early phase of the COVID-19 pandemic in Germany. Euro Surveill. 2020 Jun;25(23): Authors: Rexroth U, Hamouda O, Hanefeld J, Ruehe B, Wieler LH, Schaade L PMID: 32553063 [PubMed - in process]
Sat Jun 20, 2020 16:45
Related Articles Descriptive study of COVID-19 outbreak among passengers and crew on Diamond Princess cruise ship, Yokohama Port, Japan, 20 January to 9 February 2020. Euro Surveill. 2020 Jun;25(23): Authors: Yamagishi T, Kamiya H, Kakimoto K, Suzuki M, Wakita T Abstract An outbreak of coronavirus disease (COVID-19) occurred on the Diamond Princess cruise ship making an international journey, which led to quarantine of the ship at Yokohama Port,...
Sat Jun 20, 2020 16:45
Related Articles Meta-analysis of diagnostic performance of serological tests for SARS-CoV-2 antibodies up to 25 April 2020 and public health implications. Euro Surveill. 2020 Jun;25(23): Authors: Caini S, Bellerba F, Corso F, Díaz-Basabe A, Natoli G, Paget J, Facciotti F, De Angelis SP, Raimondi S, Palli D, Mazzarella L, Pelicci PG, Vineis P, Gandini S Abstract We reviewed the diagnostic accuracy of SARS-CoV-2 serological tests. Random-effects...
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