Recommendations for the treatment of epilepsy in adult and pediatric patients in Belgium: 2020 update. Acta Neurol Belg. 2020 Oct 13;: Authors: Boon P, Ferrao Santos S, Jansen AC, Lagae L, Legros B, Weckhuysen S Abstract To guide health care professionals in Belgium in selecting the appropriate antiepileptic drugs (AEDs) for their epilepsy patients, a group of Belgian epilepsy experts developed recommendations for AED treatment in adults and...
Wed Oct 14, 2020 21:37
Neurocutaneous melanocytosis (melanosis). Childs Nerv Syst. 2020 Oct 13;: Authors: Ruggieri M, Polizzi A, Catanzaro S, Bianco ML, Praticò AD, Di Rocco C Abstract Neurocutaneous melanosis (NCM; MIM # 249400; ORPHA: 2481], first reported by the Bohemian pathologist Rokitansky in 1861, and now more precisely defined as neurocutaneous melanocytosis, is a rare, congenital syndrome characterised by the association of (1) congenital melanocytic nevi...
Wed Oct 14, 2020 21:37
[Mitochondrial encephalopathy, lactic acidosis and stroke-like episodes / myoclonus epilepsy with ragged-red fibers /Leigh overlap syndrome caused by mitochondrial DNA 8344A>G mutation]. Beijing Da Xue Xue Bao Yi Xue Ban. 2020 Oct 18;52(5):851-855 Authors: Hou Y, Zhao XT, Xie ZY, Yuan Y, Wang ZX Abstract OBJECTIVE: Mitochondrial deoxyribonucleic acid (mtDNA) 8344 A>G (m.8344A>G) mutation is the common mutation associated with mitochondrial...
Wed Oct 14, 2020 21:37
Cardiac autonomic neuropathy in adult epilepsy patients in a tertiary hospital in South-Western Nigeria. Niger J Clin Pract. 2020 Oct;23(10):1437-1442 Authors: Adebiyi AM, Komolafe MA, Idowu AO, Omon HE, Ogunniyi A Abstract Background: Cardiac autonomic neuropathy (CAN) resulting from seizures has been implicated in sudden unexpected death in epilepsy in persons with epilepsy (PWE), however, there are no previous studies of CAN in PWE from...
Wed Oct 14, 2020 21:37
Related Articles [Convulsive syncope then convulsive seizure occurred in the long clinical course: a case report]. Rinsho Shinkeigaku. 2020 Sep 29;60(9):627-630 Authors: Sakakibara-Hayashi K, Inoue T, Kuki I, Usui M, Ikeda A, Kanda M Abstract A 17-year-old woman presented with transient consciousness impairment attack and convulsion after bathing and prolonged standing since age 12. EEG showed WHAM ( wake, high amplitude, anterior, male) type...
Wed Oct 14, 2020 21:37
Related Articles Telehealth in pediatric epilepsy care: A rapid transition during the COVID-19 pandemic. Epilepsy Behav. 2020 10;111:107282 Authors: Sattar S, Kuperman R Abstract Telehealth's first literature reference is an article in 1879 in the Lancet about using the telephone to reduce unnecessary office visits (Institute of Medicine & Board on Health Care Services, 2012). However, providers have been slow to adopt telehealth into...
Wed Oct 14, 2020 21:37
Related Articles Bridging the healthcare gap: Building the case for epilepsy virtual clinics in the current healthcare environment. Epilepsy Behav. 2020 10;111:107262 Authors: Lavin B, Dormond C, Scantlebury MH, Frouin PY, Brodie MJ Abstract Access to quality healthcare remains a challenge that is complicated by mounting pressures to control costs, and now, as we witness, the unprecedented strain placed on our healthcare delivery systems due...
Wed Oct 14, 2020 21:37
Related Articles Epilepsy self-management during a pandemic: Experiences of people with epilepsy. Epilepsy Behav. 2020 10;111:107238 Authors: Miller WR, Von Gaudecker J, Tanner A, Buelow JM Abstract The purpose of this descriptive study was to, from the perspective of adult people with epilepsy (PWE) and caregivers of PWE, explore the effects of the current pandemic and resulting societal changes on epilepsy self-management. Ninety-four respondents...
Wed Oct 14, 2020 21:37
Related Articles Neurocysticercosis-related seizures in the post-partum period: two cases and a review of the literature. Lancet Infect Dis. 2020 08;20(8):e204-e214 Authors: Ursini T, Di Giacomo R, Caldrer S, Angheben A, Zammarchi L, Filipponi S, Pizio NR, Bisoffi Z, Buonfrate D Abstract Neurocysticercosis, the infection of the CNS with larval cysts of Taenia solium, is a leading cause of seizures in low-income countries. The clinical presentation...
Wed Oct 14, 2020 21:37
Related Articles Emergency implementation of telemedicine for epilepsy in Spain: Results of a survey during SARS-CoV-2 pandemic. Epilepsy Behav. 2020 10;111:107211 Authors: Conde-Blanco E, Centeno M, Tio E, Muriana D, García-Peñas JJ, Serrano P, Nagel AG, Serratosa J, Jiménez ÁP, Toledo M, Donaire A, Manzanares I, Betrán O, Carreño M Abstract Teleneurology in Spain had not been implemented so far in clinical practice, except in urgent patients...
Wed Oct 14, 2020 21:37
Related Articles Management of Menstrual and Gynecologic Concerns in Girls with Special Needs J Clin Res Pediatr Endocrinol. 2020 Feb 06;12(Suppl 1):41-45 Authors: Dural Ö, Taş İS, Akhan SE Abstract For girls with physical and developmental disabilities and their families/caregivers, puberty and menstruation can present significant problems such as vulnerability, abuse risk, unintended pregnancies, difficulties with managing menstrual hygiene,...
Wed Oct 14, 2020 21:37
Related Articles Ictal and interictal source imaging on intracranial EEG predicts epilepsy surgery outcome in children with focal cortical dysplasia. Clin Neurophysiol. 2020 03;131(3):734-743 Authors: Alhilani M, Tamilia E, Ricci L, Ricci L, Grant PE, Madsen JR, Pearl PL, Papadelis C Abstract OBJECTIVE: To localize the seizure onset zone (SOZ) and irritative zone (IZ) using electric source imaging (ESI) on intracranial EEG (iEEG) and assess...
Wed Oct 14, 2020 21:37
Related Articles A case report of sinoatrial arrest caused by temporal lobe epilepsy in subclinical glioblastoma. BMC Cardiovasc Disord. 2020 01 30;20(1):30 Authors: Reifart J, Tschernatsch M, Hamm CW, Sperzel J, Hain A Abstract BACKGROUND: Atrial fibrillation with symptomatic bradycardia, higher grade atrioventricular block, and sinus node disease are all common indications for permanent pacemaker implantation. The most frequent causes of...
Wed Oct 14, 2020 21:37
Related Articles Sleep related epilepsy in focal cortical dysplasia type 2: Insights from sleep recordings in presurgical evaluation. Clin Neurophysiol. 2020 03;131(3):609-615 Authors: Eltze CM, Landre E, Soufflet C, Chassoux F Abstract OBJECTIVE: To determine the relationship between seizure onset, sleep stage and focal cortical dysplasia type 2 (FCD2) location in sleep related epilepsy (SRE). METHODS: We reviewed scalp video-EEG...
Wed Oct 14, 2020 21:37
Related Articles Temporal trends in incidence of Rolandic epilepsy, prevalence of comorbidities and prescribing trends: birth cohort study. Arch Dis Child. 2020 06;105(6):569-574 Authors: Stephen J, Weir CJ, Chin RF Abstract OBJECTIVE: To examine temporal trends in incidence of Rolandic epilepsy (RE), prevalence of comorbidities and antiepileptic drug (AED) prescribing patterns. DESIGN: Retrospective cohort study. SETTING:...
Wed Oct 14, 2020 21:37
Related Articles Synthesis and Evaluation of N-substituted (Z)-5-(Benzo[d][1,3]dioxol-5- ylmethylene)-2-Thioxothiazolidin-4-one Derivatives and 5-Substituted- Thioxothiazolidindione Derivatives as Potent Anticonvulsant Agents. CNS Neurol Disord Drug Targets. 2019;18(10):798-807 Authors: Dong S, Liu Y, Xu J, Hu Y, Huang L, Wang Z Abstract BACKGROUND: Epilepsy is a serious and common neurological disorder threatening the health of humans. Despite...
Wed Oct 14, 2020 21:37
Related Articles The role that choice of model plays in predictions for epilepsy surgery. Sci Rep. 2019 05 14;9(1):7351 Authors: Junges L, Lopes MA, Terry JR, Goodfellow M Abstract Mathematical modelling has been widely used to predict the effects of perturbations to brain networks. An important example is epilepsy surgery, where the perturbation in question is the removal of brain tissue in order to render the patient free of seizures. Different...
Wed Oct 14, 2020 21:37
Related Articles The Na+/H+ Exchanger Nhe1 Modulates Network Excitability via GABA Release. Cereb Cortex. 2019 09 13;29(10):4263-4276 Authors: Bocker HT, Heinrich T, Liebmann L, Hennings JC, Seemann E, Gerth M, Jakovčevski I, Preobraschenski J, Kessels MM, Westermann M, Isbrandt D, Jahn R, Qualmann B, Hübner CA Abstract Brain functions are extremely sensitive to pH changes because of the pH-dependence of proteins involved in neuronal excitability...
Wed Oct 14, 2020 21:37
A prospective multicenter study of laser ablation for drug resistant epilepsy - One year outcomes. Epilepsy Res. 2020 Sep 22;167:106473 Authors: Landazuri P, Shih J, Leuthardt E, Ben-Haim S, Neimat J, Tovar-Spinoza Z, Chiang V, Spencer D, Sun D, Fecci P, Baumgartner J Abstract OBJECTIVE: To report one-year seizure outcomes, procedural data, and quality of life scores following laser interstitial thermal therapy (LITT) of epileptogenic foci....
Tue Oct 13, 2020 22:34
Microglia/macrophages express alternative proangiogenic factors depending on granulocyte content in human glioblastoma. J Pathol. 2020 Oct 12;: Authors: Blank A, Kremenetskaia I, Urbantat RM, Acker G, Turkowski K, Radke J, Schneider UC, Vajkoczy P, Brandenburg S Abstract Myeloid cells are an inherent part of the microenvironment of glioblastoma multiforme (GBM). There is growing evidence for their participation in mechanisms of tumor escape,...
Tue Oct 13, 2020 22:34
Diagnosis and surgical treatment of non-lesional temporal lobe epilepsy with unilateral amygdala enlargement. Neurol Sci. 2020 Oct 12;: Authors: Fan Z, Sun B, Lang LQ, Hu J, Hameed NUF, Wei ZX, Zhuang QY, Cai JJ, Liu FT, Mao YT, Feng R, Pan L Abstract OBJECTIVE: Exploring the role of amygdala enlargement (AE) in temporal lobe epilepsy (TLE) without ipsilateral mesial temporal sclerosis (MTS) using comprehensive presurgical workup tools including...
Tue Oct 13, 2020 22:34
Targeted Neuronal Injury for the Non-Invasive Disconnection of Brain Circuitry. J Vis Exp. 2020 Sep 27;(163): Authors: Wang W, Zhang Y, Anzivino MJ, Bertram EH, Woznak J, Klibanov A, Dumont E, Wintermark M, Lee KS Abstract Surgical intervention can be quite effective for treating certain types of medically intractable neurological diseases. This approach is particularly useful for disorders in which identifiable neuronal circuitry plays a key...
Tue Oct 13, 2020 22:34
Left Bundle Branch Block: A Reversible Pernicious Effect of Lacosamide. Cureus. 2020 Sep 03;12(9):e10234 Authors: Majmundar MM, Kansara T, Shah P, Zala H, Chaudhari S Abstract A 95-year-old male with a medical history of focal epilepsy presented with transient ischemic attack (TIA)/pre-syncope like symptoms. He was on lacosamide (LCM) and levetiracetam. On evaluation, he was found to have left bundle branch block (LBBB), sinus pause of three...
Tue Oct 13, 2020 22:34
Effect of Levetiracetam Usage on Serum Creatine Phosphokinase Concentration in Patients with Epilepsy. J Pediatr Neurosci. 2020 Apr-Jun;15(2):81-85 Authors: Incecik F, Herguner OM, Besen S Abstract Background: Levetiracetam (LEV) is a widely used antiepileptic drug (AED) in the treatment of various type of seizures, including generalized epileptic seizure as well as focal seizures, and it is generally well tolerated. Common side effects of...
Tue Oct 13, 2020 22:34
Acute Phase Serum Leptin, Adiponectin, Interleukin-6, and Visfatin Are Altered in Chinese Children With Febrile Seizures: A Cross-Sectional Study. Front Endocrinol (Lausanne). 2020;11:531 Authors: Chen JR, Jin MF, Tang L, Liu YY, Ni H Abstract Adipokines, including leptin, visfatin, adiponectin, and interleukin-6 (IL)-6, play multiple roles in the pathophysiology of epilepsy and febrile seizures (FS). We aimed to investigate the associations...
Tue Oct 13, 2020 22:34
Mortality Rates in People With Convulsive Epilepsy in Rural Northeast China. Front Neurol. 2020;11:1013 Authors: Li J, Zhang X, Li N, Zhao D, Li G, Lin W Abstract Purpose: To examine the mortality rate and causes of death of phenobarbital (PB) monotherapy and sodium valproate (VPA) monotherapy in patients with convulsive epilepsy in rural northeast China and compare the differences in the results between the two antiepileptic drugs. Methods:...
Tue Oct 13, 2020 22:34
Stress and Tinnitus; Transcutaneous Auricular Vagal Nerve Stimulation Attenuates Tinnitus-Triggered Stress Reaction. Front Psychol. 2020;11:570196 Authors: Ylikoski J, Markkanen M, Pirvola U, Lehtimäki JA, Ylikoski M, Jing Z, Sinkkonen ST, Mäkitie A Abstract Introduction: Tinnitus can become a strong stressor for some individuals, leading to imbalance of the autonomous nervous system with reduction of parasympathetic activity. It can manifest...
Tue Oct 13, 2020 22:34
Mechanism of Zinc Excitotoxicity: A Focus on AMPK. Front Neurosci. 2020;14:577958 Authors: Kim YH, Eom JW, Koh JY Abstract Over the last 20 years, it has been shown that complex signaling cascades are involved in zinc excitotoxicity. Free zinc rapidly induces PKC activation, which causes reactive oxygen species (ROS) production at least in part through NADPH oxidase. It also promotes neuronal nitric oxide synthase, thereby increasing nitric...
Tue Oct 13, 2020 22:34
Epilepsy miRNA Profile Depends on the Age of Onset in Humans and Rats. Front Neurosci. 2020;14:924 Authors: Baloun J, Bencurova P, Totkova T, Kubova H, Hermanova M, Hendrych M, Pail M, Pospisilova S, Brazdil M Abstract Temporal lobe epilepsy (TLE) is a severe neurological disorder accompanied by recurrent spontaneous seizures. Although the knowledge of TLE onset is still incomplete, TLE pathogenesis most likely involves the aberrant expression...
Tue Oct 13, 2020 22:34
Empowering seizure management skills: Knowledge, attitudes, and experiences of school staff trained in administering rescue drugs in Northern Italy. Epilepsy Behav. 2020 Oct 08;:107362 Authors: Bert F, Pompili E, Gualano MR, Venuti S, Minniti D, Siliquini R Abstract PURPOSE: The administration of rescue medication at school concerns students for which it may be essential, on doctor's prescription, to take therapy during school hours. In this...
Tue Oct 13, 2020 22:34
Functional Distinction between Human and Mouse Sodium-Coupled Citrate Transporters and Its Biologic Significance: An Attempt for Structural Basis Using a Homology Modeling Approach. Chem Rev. 2020 Oct 11;: Authors: Jaramillo-Martinez V, Urbatsch IL, Ganapathy V Abstract NaCT (SLC13A5; mINDY), a sodium-coupled citrate transporter, is the mammalian ortholog of Drosophila INDY. Loss-of-function mutations in human NaCT cause severe complications...
Tue Oct 13, 2020 22:34
Pembrolizumab and other immune checkpoint inhibitors in locally advanced or metastatic merkel cell carcinoma: safety and efficacy. Expert Rev Anticancer Ther. 2020 Oct 12;: Authors: Marchand A, Kervarrec T, Bhatia S, Samimi M Abstract INTRODUCTION: Merkel Cell Carcinoma (MCC) is a rare aggressive skin cancer, mostly affecting elderly patients. Until recently, patients with advanced disease were treated with cytotoxic chemotherapies despite...
Tue Oct 13, 2020 23:25
The value of tumor mutational burden to select patients for immunotherapy. Expert Rev Anticancer Ther. 2020 Oct 10;:1-3 Authors: Wagener-Ryczek S, Buettner R PMID: 33043725 [PubMed - as supplied by publisher]
Tue Oct 13, 2020 23:25
Immune dysfunction in MGAT2-CDG: A clinical report and review of the literature. Am J Med Genet A. 2020 Oct 12;: Authors: Poskanzer SA, Schultz MJ, Turgeon CT, Vidal-Folch N, Liedtke K, Oglesbee D, Gavrilov DK, Tortorelli S, Matern D, Rinaldo P, Bennett JT, Thies JM, Chang IJ, Beck AE, Raymond K, Allenspach EJ, Lam C Abstract Glycosylation is a critical post/peri-translational modification required for the appropriate development and function...
Tue Oct 13, 2020 22:15
DNA Methylation-Dependent Dysregulation of GABAergic Interneuron Functionality in Neuropsychiatric Diseases. Front Neurosci. 2020;14:586133 Authors: Linde J, Zimmer-Bensch G Abstract Neuropsychiatric diseases, such as mood disorders, schizophrenia, and autism, represent multifactorial disorders, differing in causes, disease onset, severity, and symptoms. A common feature of numerous neuropsychiatric conditions are defects in the cortical inhibitory...
Tue Oct 13, 2020 22:11
Early Disruption of Cortical Sleep-Related Oscillations in a Mouse Model of Dementia With Lewy Bodies (DLB) Expressing Human Mutant (A30P) Alpha-Synuclein. Front Neurosci. 2020;14:579867 Authors: Stylianou M, Zaaimi B, Thomas A, Taylor JP, LeBeau FEN Abstract Changes in sleep behavior and sleep-related cortical activity have been reported in conditions associated with abnormal alpha-synuclein (α-syn) expression, in particular Parkinson's disease...
Tue Oct 13, 2020 22:11
Mechanism of Zinc Excitotoxicity: A Focus on AMPK. Front Neurosci. 2020;14:577958 Authors: Kim YH, Eom JW, Koh JY Abstract Over the last 20 years, it has been shown that complex signaling cascades are involved in zinc excitotoxicity. Free zinc rapidly induces PKC activation, which causes reactive oxygen species (ROS) production at least in part through NADPH oxidase. It also promotes neuronal nitric oxide synthase, thereby increasing nitric...
Tue Oct 13, 2020 22:11
FFA-DMRI: A Network Based on Feature Fusion and Attention Mechanism for Brain MRI Denoising. Front Neurosci. 2020;14:577937 Authors: Hong D, Huang C, Yang C, Li J, Qian Y, Cai C Abstract Magnetic Resonance Imaging (MRI) is an indispensable tool in the diagnosis of brain diseases due to painlessness and safety. Nevertheless, Rician noise is inevitably injected during the image acquisition process, which leads to poor observation and interferes...
Tue Oct 13, 2020 22:11
The Role of Autophagy in Manganese-Induced Neurotoxicity. Front Neurosci. 2020;14:574750 Authors: Yan DY, Xu B Abstract Manganese (Mn), an essential micronutrient, acts as a cofactor for multiple enzymes. Epidemiological investigations have shown that an excessive level of Mn is an important environmental factor involved in neurotoxicity. Frequent pollution of air and water by Mn is a serious threat to the health of the population. Overexposure...
Tue Oct 13, 2020 22:11
Paramagnetic Metal Accumulation in the Deep Gray Matter Nuclei Is Associated With Neurodegeneration in Wilson's Disease. Front Neurosci. 2020;14:573633 Authors: Yuan XZ, Li GY, Chen JL, Li JQ, Wang XP Abstract Background: Neuropathological studies have revealed copper and iron accumulation in the deep gray matter (DGM) nuclei of patients with Wilson's disease (WD). However, the association between metal accumulation and neurodegeneration in...
Tue Oct 13, 2020 22:11
Cold Exposure After Exercise Impedes the Neuroprotective Effects of Exercise on Thermoregulation and UCP4 Expression in an MPTP-Induced Parkinsonian Mouse Model. Front Neurosci. 2020;14:573509 Authors: Tsai YJ, Jhong YC, Ching SH, Liao YC, Ching CH, Chuang JI Abstract Moderate exercise and mild hypothermia have protective effects against brain injury and neurodegeneration. Running in a cold environment alters exercise-induced hyperthermia...
Tue Oct 13, 2020 22:11
Susceptibility and Volume Measures of the Mammillary Bodies Between Mild Cognitively Impaired Patients and Healthy Controls. Front Neurosci. 2020;14:572595 Authors: Jin Z, Sethi SK, Li B, Tang R, Li Y, Hsu CC, He N, Haacke EM, Yan F Abstract Purpose: To investigate the baseline values and differences for susceptibility and volume of the mammillary bodies between mild cognitively impaired (MCI) patients and healthy controls (HCs), and further...
Tue Oct 13, 2020 22:11
Spatial Mechanisms for Segregation of Competing Sounds, and a Breakdown in Spatial Hearing. Front Neurosci. 2020;14:571095 Authors: Middlebrooks JC, Waters MF Abstract We live in complex auditory environments, in which we are confronted with multiple competing sounds, including the cacophony of talkers in busy markets, classrooms, offices, etc. The purpose of this article is to synthesize observations from a series of experiments that focused...
Tue Oct 13, 2020 22:11
Neuroanatomical and Microglial Alterations in the Striatum of Levodopa-Treated, Dyskinetic Hemi-Parkinsonian Rats. Front Neurosci. 2020;14:567222 Authors: Fletcher EJR, Finlay CJ, Amor Lopez A, Crum WR, Vernon AC, Duty S Abstract Dyskinesia associated with chronic levodopa treatment in Parkinson's disease is associated with maladaptive striatal plasticity. The objective of this study was to examine whether macroscale structural changes, as...
Tue Oct 13, 2020 22:11
Reproducibility of Glutamate, Glutathione, and GABA Measurements in vivo by Single-Voxel STEAM Magnetic Resonance Spectroscopy at 7-Tesla in Healthy Individuals. Front Neurosci. 2020;14:566643 Authors: Gonen OM, Moffat BA, Kwan P, O'Brien TJ, Desmond PM, Lui E Abstract Background and Purpose: Derangements in brain glutamate, glutathione, and γ-amino butyric acid (GABA) are implicated in a range of neurological disorders. Reliable methods to...
Tue Oct 13, 2020 22:11
Standardized and Experimental Tools to Assess Spatial Cognition in Visually Impaired Children: A Mini-Review. Front Neurosci. 2020;14:562589 Authors: Aprile G, Cappagli G, Morelli F, Gori M, Signorini S Abstract The acquisition of spatial cognition is essential for both everyday functioning (e.g., navigation) and more specific goals (e.g., mathematics), therefore being able to assess and monitor spatial cognition from the first years of life...
Tue Oct 13, 2020 22:11
A Novel Mouse Model of Aminoglycoside-Induced Hyperacusis and Tinnitus. Front Neurosci. 2020;14:561185 Authors: Longenecker RJ, Gu R, Homan J, Kil J Abstract Aminoglycosides (AG) such as amikacin are commonly used in cystic fibrosis patients with opportunistic pulmonary infections including multi-drug resistant mycobacterium tuberculous and non-tuberculous mycobacterium. Unfortunately, this class of drugs is known to cause peripheral damage...
Tue Oct 13, 2020 22:11
Prognostic Indicators for Positive Treatment Outcome After Multidisciplinary Orofacial Treatment in Patients With Somatosensory Tinnitus. Front Neurosci. 2020;14:561038 Authors: van der Wal A, Van de Heyning P, Gilles A, Jacquemin L, Topsakal V, Van Rompaey V, Braem M, Visscher CM, Truijen S, Michiels S, De Hertogh W Abstract Introduction: Subjective tinnitus that is influenced by the somatosensory system is called somatosensory tinnitus (ST)....
Tue Oct 13, 2020 22:11
Electrophysiological and Neuroimaging Studies - During Resting State and Sensory Stimulation in Disorders of Consciousness: A Review. Front Neurosci. 2020;14:555093 Authors: Jain R, Ramakrishnan AG Abstract A severe brain injury may lead to a disorder of consciousness (DOC) such as coma, vegetative state (VS), minimally conscious state (MCS) or locked-in syndrome (LIS). Till date, the diagnosis of DOC relies only on clinical evaluation or...
Tue Oct 13, 2020 22:11
Relationship Between Basic Properties of BOLD Fluctuations and Calculated Metrics of Complexity in the Human Connectome Project. Front Neurosci. 2020;14:550923 Authors: Keilholz S, Maltbie E, Zhang X, Yousefi B, Pan WJ, Xu N, Nezafati M, LaGrow TJ, Guo Y Abstract Resting state functional MRI (rs-fMRI) creates a rich four-dimensional data set that can be analyzed in a variety of ways. As more researchers come to view the brain as a complex...
Tue Oct 13, 2020 22:11
Initial Experience of Challenge-Free MRI-Based Oxygen Extraction Fraction Mapping of Ischemic Stroke at Various Stages: Comparison With Perfusion and Diffusion Mapping. Front Neurosci. 2020;14:535441 Authors: Zhang S, Cho J, Nguyen TD, Spincemaille P, Gupta A, Zhu W, Wang Y Abstract MRI-based oxygen extraction fraction imaging has a great potential benefit in the selection of clinical strategies for ischemic stroke patients. This study aimed...
Tue Oct 13, 2020 22:11
Exploring Neuromodulation for Dynamic Learning. Front Neurosci. 2020;14:928 Authors: Daram A, Yanguas-Gil A, Kudithipudi D Abstract A continual learning system requires the ability to dynamically adapt and generalize to new tasks with access to only a few samples. In the central nervous system, across species, it is observed that continual and dynamic behavior in learning is an active result of a mechanism known as neuromodulation. Therefore,...
Tue Oct 13, 2020 22:11
Epilepsy miRNA Profile Depends on the Age of Onset in Humans and Rats. Front Neurosci. 2020;14:924 Authors: Baloun J, Bencurova P, Totkova T, Kubova H, Hermanova M, Hendrych M, Pail M, Pospisilova S, Brazdil M Abstract Temporal lobe epilepsy (TLE) is a severe neurological disorder accompanied by recurrent spontaneous seizures. Although the knowledge of TLE onset is still incomplete, TLE pathogenesis most likely involves the aberrant expression...
Tue Oct 13, 2020 22:11
Effects of Oral Gamma-Aminobutyric Acid (GABA) Administration on Stress and Sleep in Humans: A Systematic Review. Front Neurosci. 2020;14:923 Authors: Hepsomali P, Groeger JA, Nishihira J, Scholey A Abstract Gamma-aminobutyric acid (GABA) is a non-proteinogenic amino acid and is the main inhibitory neurotransmitter in the mammalian brain. GABA's stress-reducing, and sleep enhancing effects have been established. However, although several human...
Tue Oct 13, 2020 22:11
Alzheimer's Retinopathy: Seeing Disease in the Eyes. Front Neurosci. 2020;14:921 Authors: Mirzaei N, Shi H, Oviatt M, Doustar J, Rentsendorj A, Fuchs DT, Sheyn J, Black KL, Koronyo Y, Koronyo-Hamaoui M Abstract The neurosensory retina emerges as a prominent site of Alzheimer's disease (AD) pathology. As a CNS extension of the brain, the neuro retina is easily accessible for noninvasive, high-resolution imaging. Studies have shown that along...
Tue Oct 13, 2020 22:11
Pyneal: Open Source Real-Time fMRI Software. Front Neurosci. 2020;14:900 Authors: MacInnes JJ, Adcock RA, Stocco A, Prat CS, Rao RPN, Dickerson KC Abstract Increasingly, neuroimaging researchers are exploring the use of real-time functional magnetic resonance imaging (rt-fMRI) as a way to access a participant's ongoing brain function throughout a scan. This approach presents novel and exciting experimental applications ranging from monitoring...
Tue Oct 13, 2020 22:11
Early Prediction of Cognitive Deficit in Very Preterm Infants Using Brain Structural Connectome With Transfer Learning Enhanced Deep Convolutional Neural Networks. Front Neurosci. 2020;14:858 Authors: Chen M, Li H, Wang J, Yuan W, Altaye M, Parikh NA, He L Abstract Up to 40% of very preterm infants (≤32 weeks' gestational age) were identified with a cognitive deficit at 2 years of age. Yet, accurate clinical diagnosis of cognitive deficit...
Tue Oct 13, 2020 22:11
Mapping the Interactive Effects of ApoE Gene Polymorphism on Caudate Functional Connectivity in Mild Cognitive Impairment Associated With Parkinson's Disease. Front Neurosci. 2020;14:857 Authors: Shang S, Chen YC, Zhang H, Dou W, Qian L, Yin X, Wu J Abstract Introduction: Cognitive impairment (CI) is a frequent non-motor symptom of Parkinson's disease (PD). Caudate and Apolipoprotein E (ApoE) are biomarkers linked to CI in PD. There is little...
Tue Oct 13, 2020 22:11
Linking Pain Sensation to the Autonomic Nervous System: The Role of the Anterior Cingulate and Periaqueductal Gray Resting-State Networks. Front Neurosci. 2020;14:147 Authors: Hohenschurz-Schmidt DJ, Calcagnini G, Dipasquale O, Jackson JB, Medina S, O'Daly O, O'Muircheartaigh J, de Lara Rubio A, Williams SCR, McMahon SB, Makovac E, Howard MA Abstract There are bi-directional interactions between the autonomic nervous system (ANS) and pain....
Tue Oct 13, 2020 22:11
27 new pubmed citations were retrieved for your search. Click on the search hyperlink below to display the complete search results: Future Oncology These pubmed results were generated on 2020/10/14PubMed comprises more than millions of citations for biomedical literature from MEDLINE, life science journals, and online books. Citations may include links to full-text content from PubMed Central and publisher web sites.
Wed Oct 14, 2020 21:23
25 new pubmed citations were retrieved for your search. Click on the search hyperlink below to display the complete search results: Future Oncology These pubmed results were generated on 2020/10/13PubMed comprises more than millions of citations for biomedical literature from MEDLINE, life science journals, and online books. Citations may include links to full-text content from PubMed Central and publisher web sites.
Tue Oct 13, 2020 21:26
YAP increases response to Trastuzumab in HER2-positive Breast Cancer by enhancing P73-induced apoptosis. J Cancer. 2020;11(22):6748-6759 Authors: Cao L, Yao M, Sasano H, Sun PL, Gao H Abstract The role of the Yes-associated protein (YAP) in oncogenesis and progression of breast cancer remains controversial. Meanwhile, development of therapeutic resistance to trastuzumab, a common breast cancer treatment administered after chemotherapy, is a...
01:46
Characteristics and survival of de novo and recurrent metastatic breast cancer in New Zealand. Breast Cancer. 2020 Oct 12;: Authors: Lao C, Kuper-Hommel M, Elwood M, Campbell I, Edwards M, Lawrenson R Abstract BACKGROUND: We aim to examine the characteristics and survival of patients with de novo metastatic breast cancer (dnMBC) and recurrent metastatic breast cancer (rMBC) in New Zealand. METHODS: This study included women diagnosed...
Tue Oct 13, 2020 22:04
Novel Small-Molecule Inhibitor for the Oncogenic Tyrosine Phosphatase SHP2 with Anti-Breast Cancer Cell Effects. ACS Omega. 2020 Oct 06;5(39):25113-25124 Authors: Hartman Z, Geldenhuys WJ, Agazie YM Abstract The oncogenic property of the Src homology phosphotyrosine phosphatase 2 (SHP2) is well-known, but developing specific inhibitors has been very difficult. Based on our previous reports that showed the importance of acidic residues surrounding...
Tue Oct 13, 2020 22:04
Metastatic brain tumors respond favorably to pyrotinib in a HER2-positive breast cancer following failure using trastuzumab. Am J Transl Res. 2020;12(9):5874-5881 Authors: Yao JH, Xie ZY, Li M, Zhang ML, Ci HF, Yang Y Abstract Treatment of breast cancer (BC) with overexpression of human epidermal growth factor receptor 2 (HER2) has undergone a prosperous development with the advent of emerging small molecule tyrosine kinase inhibitors (TKIs)....
Tue Oct 13, 2020 22:04
Molecular phenotype discordance between primary and synchronous metastatic lesions of breast cancer and its determinant role in guiding treatment decisions: a case report. Am J Transl Res. 2020;12(9):5866-5873 Authors: Yao JH, Zhang WQ, Shao Y, Zhu Y, Liu J, Jin GS, Yang Y Abstract Molecular phenotype discordance between primary and metastatic tumors exists in a small proportion of breast cancer (BC) patients with accessible synchronous metastases....
Tue Oct 13, 2020 22:04
Molecular Pathway Activation Markers Are Associated with Efficacy of Trastuzumab Therapy in Metastatic HER2-Positive Breast Cancer Better than Individual Gene Expression Levels. Biochemistry (Mosc). 2020 Jul;85(7):758-772 Authors: Sorokin M, Ignatev K, Barbara V, Vladimirova U, Muraveva A, Suntsova M, Gaifullin N, Vorotnikov I, Kamashev D, Bondarenko A, Baranova M, Poddubskaya E, Buzdin A Abstract Increased expression or amplification of HER2...
Tue Oct 13, 2020 22:04
[Prevalence and characteristics of obstructive sleep apneas according to severity]. Medicina (B Aires). 2020;80(5):479-486 Authors: Ernst G, Sabán M, Schiavone M, Blanco M, Salvado A, Borsini E Abstract Obstructive sleep apnea (OSA) is a prevalent condition. OSA is defined as very severe when the apneas/ hypopneas index (AHI) is greater than 60 events/hour. However, its prevalence remains uncertain. The aim of this study was to describe the...
Wed Oct 14, 2020 21:16
Clinical Radiographic Predictors of Response to Hypoglossal Nerve Stimulation for Obstructive Sleep Apnea. Otolaryngol Head Neck Surg. 2020 Oct 13;:194599820963141 Authors: Lee CH, Seay EG, Reese JW, Wu X, Schwab RJ, Keenan B, Dedhia RC Abstract OBJECTIVE: To determine if clinically acquired cephalometric measurements, specifically soft palate size, can predict hypoglossal nerve stimulation outcomes. STUDY DESIGN: Combined prospective...
Wed Oct 14, 2020 21:16
The Prevalence of Co-morbidities in Adult and Adolescent Bariatric Surgery Candidates. Obes Surg. 2020 Oct 12;: Authors: Liu J, Woo Baidal J, Fennoy I, Parkinson KL, Lynch L, Zitsman JL Abstract Severe obesity is often associated with co-morbid conditions such as diabetes mellitus, hypertension, and obstructive sleep apnea. Successful weight loss can result in remission of these conditions. The authors retrospectively examined the co-morbidity...
Wed Oct 14, 2020 21:16
Reactive oxygen species and TNF-α: the interplay between obstructive sleep apnea and Behçet's disease. Sleep Breath. 2020 Oct 12;: Authors: Le Joncour A, Cacoub P, Marques C, Saadoun D PMID: 33047240 [PubMed - as supplied by publisher]
Wed Oct 14, 2020 21:16
Treatment of Cheyne-Stokes respiration with adaptive servoventilation-analysis of patients with regard to therapy restriction. Somnologie (Berl). 2020 Oct 08;:1-6 Authors: Stieglitz S, Galetke W, Esquinas A Abstract Purpose: The SERVE-HF study revealed no benefit of adaptive servoventilation (ASV) versus guideline-based medical treatment in patients with symptomatic heart failure, an ejection fraction (EF) ≤45% and a predominance of central...
Wed Oct 14, 2020 21:16
Related Articles Response to "The problems in evaluation of sleep disordered breathing in adults with sickle cell disease". Sleep Med. 2020 07;71:162 Authors: Ayache M, Strohl KP PMID: 32107142 [PubMed - indexed for MEDLINE]
Wed Oct 14, 2020 21:16
Related Articles The problems in evaluation of sleep disordered breathing in adults with sickle cell disease. Sleep Med. 2020 07;71:161 Authors: Roizenblatt S, Togeiro SMGP, Cabanas-Pedro AC, Figueredo MS PMID: 32044227 [PubMed - indexed for MEDLINE]
Wed Oct 14, 2020 21:16
Susceptibility of obese population to COVID-19. Int J Infect Dis. 2020 Oct 09;: Authors: Kimura T, Namkoong H Abstract Obesity is a risk factor for disease severity in individuals with coronavirus disease (COVID-19). However, the increased susceptibility of this population to COVID-19 is unclear. We outline several underlying mechanisms that may explain the relationship between obesity and COVID-19 severity. Obesity has an adverse effect on...
Tue Oct 13, 2020 22:55
Does craniofacial morphology relate to sleep apnea severity reduction following weight loss intervention? A patient level meta-analysis. Sleep. 2020 Oct 12;: Authors: Sutherland K, Chapman JL, Cayanan EA, Lowth AB, Hoyos CM, Wong KKH, Yee BJ, Grunstein RR, Cistulli PA, Marshall NS Abstract STUDY OBJECTIVES: Obesity is a common and reversible risk factor for Obstructive Sleep Apnea (OSA). However there is substantial unexplained variability...
Tue Oct 13, 2020 22:55
Differential associations of hypoxia, sleep fragmentation and depressive symptoms with cognitive dysfunction in obstructive sleep apnoea. Sleep. 2020 Oct 12;: Authors: Alomri RM, Kennedy GA, Wali SO, Ahejaili F, Robinson SR Abstract Obstructive sleep apnoea (OSA) is characterized by recurrent episodes of partial or complete cessation of breathing during sleep and increased effort to breathe. This study examined patients who underwent overnight...
Tue Oct 13, 2020 22:55
Mandibular advancement devices shorten desaturation duration in patients at high risk for obstructive sleep apnea syndrome during intravenous propofol sedation in the decubitus position. J Chin Med Assoc. 2020 Sep 30;: Authors: Chang C, Hsu YT, Ting CK, Tsou MY, Teng WN Abstract BACKGROUND: The purpose of this study was to determine the efficacy of a mandibular advancement device (MAD) for increasing patient safety during sedated total knee...
Tue Oct 13, 2020 22:55
An evaluation of rural-urban disparities in treatment outcomes for obstructive sleep apnoea: study protocol for a prospective cohort study. ERJ Open Res. 2020 Oct;6(4): Authors: Corrigan J, Ogah I, Ip-Buting A, Sharpe H, Laratta CR, Peller P, Tsai WH, Pendharkar SR Abstract Background: Obstructive sleep apnoea (OSA) is a common and treatable chronic condition that is associated with significant morbidity and economic cost. Geography is increasingly...
Tue Oct 13, 2020 22:55
Red cell distribution width: a new tool for the severity prediction of sleep apnoea syndrome in children. ERJ Open Res. 2020 Oct;6(4): Authors: Morell-Garcia D, Toledo-Pons N, Sanchis P, Bauça JM, Sánchez JM, Peña-Zarza J, Giménez P, Pierola J, de la Peña-Bravo M, Alonso-Fernández A, Barceló A Abstract Introduction: Red cell distribution width (RDW) is a parameter included in the complete blood count which informs about the size of the circulating...
Tue Oct 13, 2020 22:55
The Awareness of Negative Pressure Pulmonary Edema in the Medical Intensive Care Unit. Cureus. 2020 Sep 04;12(9):e10251 Authors: Zhang Q, Vayalumkal J, Ricely J, Elrod S, Raza A Abstract Negative pressure pulmonary edema (NPPE) is a noncardiogenic-related rapid onset of bilateral pulmonary edema secondary to various etiologies that lead to upper airway obstruction. Despite the fact that it is more commonly seen in the emergency department...
Tue Oct 13, 2020 22:55
Obstructive Sleep Apnoea Syndrome: Continuous Positive Airway Pressure Therapy for Prevention of Cardiovascular Risk. Eur Cardiol. 2020 Feb;15:e65 Authors: Resano-Barrio MP, Arroyo-Espliguero R, Viana-Llamas MC, Mediano O Abstract Obstructive sleep apnoea (OSA) syndrome is characterised by the presence of apnoea or obstructive hypopnoea during sleep, accompanied by hypoxia. It is estimated that the syndrome affects approximately 10% of men...
Tue Oct 13, 2020 22:55
Gradual reduction in the STOP score in patients with obstructive sleep apnea undergoing oral appliance therapy. J Prosthodont Res. 2020 Oct 09;: Authors: Narahara-Eno Y, Fukuda T, Taga H, Nakayama H, Inoue Y, Tsuiki S Abstract PURPOSE: In the treatment of obstructive sleep apnea (OSA), there is not yet a convenient tool for deciding whether a mandibular advancement oral appliance (OA) is adequately adjusted or when to perform post-treatment...
Tue Oct 13, 2020 22:55
[Clinical value of upper airway MSCT measurement in adult male patients with moderate to severe OSA]. Lin Chung Er Bi Yan Hou Tou Jing Wai Ke Za Zhi. 2020 Sep;34(9):814-819 Authors: Guo C, Long P, Ye J, Li H Abstract Objective:To investigate the pathogenesis of OSA-related through 128-slice spiral CT measurements of adult male patients with moderate to severe OSA at different respiratory phases, and to optimize treatment options for patients...
Tue Oct 13, 2020 22:55
[A modified STOP-Bang questionnaire for OSA screening in the young, middle-age women]. Lin Chung Er Bi Yan Hou Tou Jing Wai Ke Za Zhi. 2020 Sep;34(9):811-814 Authors: Chen X, Zhang R, Jia J, Yuan W, Li J Abstract Objective:The STOP-Bang（S-B） questionnaire is widely used for screening patients with OSA. However, BMI and NC cutoff value in the original S-B questionnaire is 35 kg/m²and 40cm, the BMI and NC value in the young and middle-aged female...
Tue Oct 13, 2020 22:55
A Chinese case of X-linked acrogigantism and systemic review. Neuroendocrinology. 2020 Oct 13;: Authors: Liang H, Gong F, Liu Z, Yang Y, Yao Y, Wang R, Wang L, Chen M, Pan H, Zhu H Abstract INTRODUCTION: To describe a Chinese case of X-linked acrogigantism (X-LAG) and summarize the characteristics and treatment of all reported cases. METHODS: Clinical materials and biological samples from a 5-year and 2-month-old female due to "growth...
Wed Oct 14, 2020 21:04
Related Articles Relationships Between Poor Health and Calories From Fat Among Commercial Truck Drivers. J Occup Environ Med. 2019 11;61(11):944-948 Authors: Okorie O, Thiese MS, Murtaugh MA, Sheng X, Handy R, Hegmann K Abstract OBJECTIVE: Commercial motor vehicle (CMV) drivers face many challenges to their health, including poor diet, disease, and crash risk. This study quantifies relationships between the percentage of calories from fat (PCF)...
Wed Oct 14, 2020 21:04
Mandibular advancement devices shorten desaturation duration in patients at high risk for obstructive sleep apnea syndrome during intravenous propofol sedation in the decubitus position. J Chin Med Assoc. 2020 Sep 30;: Authors: Chang C, Hsu YT, Ting CK, Tsou MY, Teng WN Abstract BACKGROUND: The purpose of this study was to determine the efficacy of a mandibular advancement device (MAD) for increasing patient safety during sedated total knee...
Wed Oct 14, 2020 01:14
Red cell distribution width: a new tool for the severity prediction of sleep apnoea syndrome in children. ERJ Open Res. 2020 Oct;6(4): Authors: Morell-Garcia D, Toledo-Pons N, Sanchis P, Bauça JM, Sánchez JM, Peña-Zarza J, Giménez P, Pierola J, de la Peña-Bravo M, Alonso-Fernández A, Barceló A Abstract Introduction: Red cell distribution width (RDW) is a parameter included in the complete blood count which informs about the size of the circulating...
Wed Oct 14, 2020 01:14
Gradual reduction in the STOP score in patients with obstructive sleep apnea undergoing oral appliance therapy. J Prosthodont Res. 2020 Oct 09;: Authors: Narahara-Eno Y, Fukuda T, Taga H, Nakayama H, Inoue Y, Tsuiki S Abstract PURPOSE: In the treatment of obstructive sleep apnea (OSA), there is not yet a convenient tool for deciding whether a mandibular advancement oral appliance (OA) is adequately adjusted or when to perform post-treatment...
Wed Oct 14, 2020 01:14
[Thyroglossal duct remnants detected by ultrasonography after total thyroidectomy for thyroid carcinoma]. Medicina (B Aires). 2020;80(5):447-452 Authors: Jerkovich F, Rizzo L, Fanti JE, Fanti MF, Pitoia F Abstract There are numerous reports of incidental findings of thyroglossal duct remnants (TGDR) after total thyroidectomy, but its implication on the outcome of patients with differentiated thyroid cancer (DTC) is unknown. The aim of...
Wed Oct 14, 2020 21:12
Body-size-dependent Iodine-131 S values. J Radiol Prot. 2020 Oct 12;: Authors: Yeom YS, Griffin KT, Shin B, Choi C, Han H, Moon S Abstract In a recent epidemiologic risk assessment on late health effects of patients treated with radioactive iodine (RAI), organ/tissue doses of the patients were estimated based on iodine-131 S values derived from the reference computational phantoms of the International Commission on Radiological Protection...
Tue Oct 13, 2020 21:25
Least Significant Changes and Reproducibility of 131I Uptake Test. Health Phys. 2020 Oct 07;: Authors: Şahmaran T, Gültekin SS Abstract Radioactive iodine uptake (RAIU) is one of the important tests performed in the departments of nuclear medicine, testing thyroid function by measuring the amount of I uptake after oral administration. A RAIU value measured 4 and 24 h after administration has been widely used for differential diagnosis...
Tue Oct 13, 2020 21:25
Preoperative Use of Intravenous Contrast Media Is Associated With Decreased Excellent Response Rates in Intermediate-Risk DTC Patients Who Subsequently Receive Total Thyroidectomy and Low-Dose RAI Therapy. Front Oncol. 2020;10:1297 Authors: Lan W, Renjie W, Qichang W, Feiyue T, Qingjie M, Bin J Abstract Purpose: To evaluate the impact of preoperative use of intravenous contrast media (ICM) on the excellent response (ER) rates in a cohort of...
Tue Oct 13, 2020 21:25
Independent muscle of extensor hallucis capsularis: a cadaveric case report. Surg Radiol Anat. 2020 Oct 13;: Authors: Park JH, Choi YJ, Park KR, Kim D, Kwon HW, Lee M, Cho J Abstract Extensor hallucis capsularis (EHC) is an accessory tendon located medially to extensor halluces longus (EHL) tendon. Most EHC is known to originate as a tendinous slip of the EHL tendon, although it may be splitted from the tibialis anterior (TA) tendon or...
Wed Oct 14, 2020 22:28
Comparison of fetal and adult tympanic membrane sizes: a cadaveric study. Surg Radiol Anat. 2020 Oct 13;: Authors: Beger O, Vayisoğlu Y, Örs AB, Özdemir DL, Müdüroğlu F, Taghipour P, Dağtekin O, Talas DÜ Abstract OBJECTIVE: The work aimed to compare fetal and adult tympanic membrane (TM) sizes for understanding dimensional development from intrauterine life to adulthood. METHODS: Fifty-six temporal bones (18 fetuses, 10 elderly...
Wed Oct 14, 2020 22:28
Osteocutaneous proximal fibular flap: an anatomical and computed tomographic angiographic study of skin and bone perforators. Surg Radiol Anat. 2020 Oct 12;: Authors: Sananpanich K, Boonyalapa A, Kraisarin J, Pattamapaspong N Abstract INTRODUCTION: Vascularized proximal fibular epiphyseal transfer is a reconstruction method for joints and growing bones. The authors investigated the vascular supply of the proximal fibula, including skin...
Wed Oct 14, 2020 22:28
The interosseous tuberosity of radius: a descriptive radiological and cadaveric anatomical study. Surg Radiol Anat. 2020 Oct 12;: Authors: Rougereau G, Valteau B, Creze M, Soubeyrand M Abstract PURPOSE: The radius is described with a single tuberosity: the radial tuberosity. However, we hypothesize that there is a second tuberosity on the interosseous border of the radius: which we propose to call the interosseous tuberosity - Tuberositas...
Wed Oct 14, 2020 22:28
Classification of various sources of error in range assessment using proton radiography and neural networks in head and neck cancer patients. Phys Med Biol. 2020 Oct 13;: Authors: Seller Oria C, Marmitt GG, Both S, Langendijk JA, Knopf AC, Meijers A Abstract This study evaluates the suitability of convolutional neural networks (CNN) to automatically process proton radiography (PR) based images. CNNs are used to classify PR images impaired by...
Wed Oct 14, 2020 21:35
Pediatric cranial osteoblastoma: Technical note of surgical treatment and review of the literature. Neurochirurgie. 2020 Oct 10;: Authors: Garvayo M, Cossu G, Broome M, Maeder P, Renella R, Maduri R, Daniel RT, Messerer M Abstract Osteoblastoma of the skull is a rare entity, and they account only for 2-4% of all the cases of osteoblastoma. We perform a comprehensive review of the pertinent literature on the subject and we report a case of a...
Wed Oct 14, 2020 21:35
Mean platelet volume and platelet distribution width serve as prognostic biomarkers in skull base chordoma: a retrospective study. BMC Cancer. 2020 Oct 12;20(1):988 Authors: Li M, Bai J, Wang S, Zhai Y, Zhang S, Li C, Du J, Zhang Y Abstract BACKGROUND: Increasing studies have demonstrated that activated platelets play an essential role in tumour progression. However, the level and prognostic role of platelet indices in chordoma patients remain...
Wed Oct 14, 2020 21:35
[Endoscope-assisted transoral resection of parapharyngeal space tumors: a retrospective study]. Lin Chung Er Bi Yan Hou Tou Jing Wai Ke Za Zhi. 2020 Sep;34(9):824-827;835 Authors: He L, Xie J, Gao X Abstract Objective:To evaluate the feasibility and safety of the endoscope-assisted transoral approach for the parapharyngeal space（PPS） tumors. Method:This retrospective study included 22 patients who were diagnosed with PPS tumors and treated...
Wed Oct 14, 2020 21:35
Related Articles The oblique occipital sinus - implications in posterior fossa approaches. J Clin Neurosci. 2020 Jun;76:202-204 Authors: Candanedo C, Moscovici S, Kaye AH, Spektor S Abstract The retrosigmoid craniotomy is the standard approach to resect pathologies in the cerebellopontine angle (CPA). Following the craniotomy, the dura mater is opened in the inferolateral direction and the basal cistern arachnoid is dissected in order to release...
Wed Oct 14, 2020 21:35
Related Articles Corticosteroid use in sudden sensorineural hearing loss and the risk of osteonecrosis: a potential medicolegal pitfall. ANZ J Surg. 2019 12;89(12):1540-1541 Authors: Bazzi K, Grierson K, Fagan P PMID: 31846567 [PubMed - indexed for MEDLINE]
Wed Oct 14, 2020 21:35
Related Articles Clinical and Molecular Study of ELMO-2-Related Massive Intraosseous Vascular Malformations: Lessons Learned From 25 Years of Follow-up. Ann Plast Surg. 2019 09;83(3):293-299 Authors: Vargel I, Calis M, Canter HI, Cil BE Abstract Massive intraosseous vascular malformations, a relatively rare entity in the vascular malformation spectrum, deserves attention as involving the membranous bones of the craniofacial skeleton and may...
Wed Oct 14, 2020 21:35
Bilateral Sequential Spontaneous Otogenic Pneumocephalus, Lessons in Pathophysiology, and Management of a Rare Case. Otol Neurotol. 2020 Oct 09;: Authors: Shapiro SB, Lipschitz N, Tumlin P, Krueger B, Forbes J, Samy RN Abstract OBJECTIVE: Report the details of an unusual case of initially unilateral intradural spontaneous otogenic pneumocephalus in which the patient developed contralateral pneumocephalus after surgical repair of temporal bone...
Tue Oct 13, 2020 21:24
Is it possible to predict the development of diabetes insipidus after pituitary surgery? Study of 241 endoscopic transsphenoidal pituitary surgeries. J Endocrinol Invest. 2020 Oct 11;: Authors: Araujo-Castro M, Mariño-Sánchez F, Acitores Cancela A, García Fernández A, García Duque S, Rodríguez Berrocal V Abstract PURPOSE: To identify presurgical and surgical factors associated with the development of diabetes insipidus (DI) after pituitary...
Tue Oct 13, 2020 21:24
Management of large intraventricular meningiomas with minimally invasive port technique: a three-case series. Neurosurg Rev. 2020 Oct 12;: Authors: Jamshidi AO, Beer-Furlan A, Hardesty DA, Ditzel Filho LFS, Prevedello LM, Prevedello DM Abstract The use of minimally invasive transcranial ports for the resection of deep-seated lesions has been shown to be safe and effective. To date, most of the literature regarding the tubular retractors used...
Tue Oct 13, 2020 21:24
Particle Beam Radiation Therapy for Skull Base Sarcomas. Front Oncol. 2020;10:1368 Authors: Yang J, Hu W, Guan X, Hu J, Gao J, Qiu X, Huang Q, Zhang W, Kong L, Lu JJ Abstract Background: To report the clinical experience of carbon-ion and proton radiation therapy for skull base sarcomas. Methods: An analysis of the retrospective data registry from the Shanghai Proton and Heavy Ion Center for patients with skull base sarcomas was conducted....
Tue Oct 13, 2020 21:24
Intraoperative Neurophysiological Monitoring During Trigeminal Schwannoma Surgery. Cureus. 2020 Sep 03;12(9):e10218 Authors: Jahangiri FR, Azam A, Asdi RA, Ahmad I, Basha SI Abstract Surgical manipulation during skull base surgeries places various cranial nerves (CN) at risk, including the nerves innervating the extraocular muscles. It could be very challenging for the surgeon to identify these cranial nerves due to the distortion of the normal...
Tue Oct 13, 2020 21:24
Neuroimaging of the Pituitary Gland: Practical Anatomy and Pathology. Radiol Clin North Am. 2020 Nov;58(6):1115-1133 Authors: Chapman PR, Singhal A, Gaddamanugu S, Prattipati V Abstract The pituitary gland is a small endocrine organ located within the sella turcica. Various pathologic conditions affect the pituitary gland and produce endocrinologic and neurologic abnormalities. The most common lesion of the pituitary gland is the adenoma, a...
Tue Oct 13, 2020 21:24
Molecular characterization of Cryptosporidium spp. from patients with diarrhoea in Lusaka, Zambia. Parasite. 2020;27:53 Authors: Mulunda NR, Hayashida K, Yamagishi J, Sianongo S, Munsaka G, Sugimoto C, Mutengo MM Abstract Cryptosporidium is a major etiological agent of diarrhoeal diseases among children and immune-compromised individuals in sub-Saharan African countries. We conducted a study to determine the prevalence and genetic characteristics...
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Single-Institute Clinical Experiences Using Whole-Field Simultaneous Integrated Boost (SIB) Intensity-Modulated Radiotherapy (IMRT) and Sequential IMRT in Postoperative Patients With Oral Cavity Cancer (OCC). Cancer Control. 2020 Jan-Dec;27(1):1073274820904702 Authors: Hsieh CH, Shueng PW, Wang LY, Liao LJ, Lo WC, Yeh HP, Chou HL, Wu LJ Abstract This study aimed to review clinical experiences using whole-field simultaneous integrated boost...
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610 new pubmed citations were retrieved for your search. Click on the search hyperlink below to display the complete search results: upper respiratory tract infection These pubmed results were generated on 2020/10/14PubMed comprises more than millions of citations for biomedical literature from MEDLINE, life science journals, and online books. Citations may include links to full-text content from PubMed Central and publisher web sites.
Wed Oct 14, 2020 22:34
Lymphocyte predominant Hodgkin lymphoma, antigen-driven after all? J Pathol. 2020 Oct 12;: Authors: Poppema S Abstract Nodular lymphocyte predominant Hodgkin lymphoma (NLPHL) was suggested as an entity separate from other types of Hodgkin lymphoma 40 years ago and recognized in the WHO classification in 2001. Based on its relatively benign course with late distant relapses, relation with lymph node hyperplasia with progressively transformed...
Tue Oct 13, 2020 22:20
Severity of Respiratory Infections With Seasonal Coronavirus Is Associated With Viral and Bacterial Coinfections. Pediatr Infect Dis J. 2020 Oct 09;: Authors: de Koff EM, van Houten MA, Sanders EAM, Bogaert D Abstract The clinical presentation of human coronavirus (HCoV) infections in children varies strongly. We show that children with an HCoV-associated lower respiratory tract infection more frequently had respiratory syncytial virus...
Tue Oct 13, 2020 22:20
Clinical implications of SARS-CoV-2 cycle threshold values in solid organ transplant recipients. Am J Transplant. 2020 Oct 12;: Authors: Gaston DC, Malinis M, Osborn R, Peaper DR, Landry M, Juthani-Mehta M, Azar MM Abstract Detection of SARS-CoV-2 viral RNA by RT-PCR assays is the primary diagnostic test for COVID-19. Cycle threshold (CT ) values generated by some of these assays provide inversely proportional proxy measurements of viral...
Tue Oct 13, 2020 22:20
Trends in pediatric hospitalizations for ambulatory care sensitive respiratory diseases in Brazil. Public Health Nurs. 2020 Oct 11;: Authors: Carneiro VSM, Vila VCDS, Vieira MADS Abstract OBJECTIVE: To analyze the trend in hospitalization rates for ambulatory care sensitive respiratory diseases (ACSRD) of children under five years of age in Brazil. DESIGN: Time series study of hospitalization rates using secondary information...
Tue Oct 13, 2020 22:20
Prolonged PCR positivity in health care workers with COVID-19: implications for practice guidelines.
Prolonged PCR positivity in health care workers with COVID-19: implications for practice guidelines. Med J Aust. 2020 Oct 12;: Authors: Chua KY, Holmes NE, Kwong J PMID: 33043456 [PubMed - as supplied by publisher]
Tue Oct 13, 2020 22:20
Associations between restrictions on public mobility and slowing of new COVID-19 case rates in three countries. Med J Aust. 2020 Oct 12;: Authors: Tran TH, Sasikumar SN, Hennessy A, O'Loughlin A, Morgan L PMID: 33043444 [PubMed - as supplied by publisher]
Tue Oct 13, 2020 22:20
A Systematic Review and Meta-analysis of Sex Differences in Morbidity and Mortality of Acute Lower Respiratory Tract Infections Among African Children. J Pediatr Rev. 2020 Apr;8(2):65-78 Authors: Orimadegun AE, Adepoju AA, Myer L Abstract Context: Although biological sex influences Acute Lower Respiratory Tract Infections (ALRIs) morbidity and mortality patterns in children living in sub-Saharan Africa, the exact mechanism about the effect...
Tue Oct 13, 2020 22:20
Seasonality of Respiratory Viral Infections: Will COVID-19 Follow Suit? Front Public Health. 2020;8:567184 Authors: Audi A, AlIbrahim M, Kaddoura M, Hijazi G, Yassine HM, Zaraket H Abstract Respiratory viruses, including coronaviruses, are known to have a high incidence of infection during winter, especially in temperate regions. Dry and cold conditions during winter are the major drivers for increased respiratory tract infections as they...
Tue Oct 13, 2020 22:20
COVID-19 Associated With Life-Threatening Apnea in an Infant Born Preterm: A Case Report. Front Pediatr. 2020;8:568 Authors: Loron G, Tromeur T, Venot P, Beck J, Andreoletti L, Mauran P, Bednarek N Abstract A pandemic linked to the new coronavirus strain (SARS-CoV-2) has been raging for several months. Pediatric populations are less impacted than adults, and critical respiratory diseases seem rare (1, 2). We report the case of an infant, who...
Tue Oct 13, 2020 22:20
Seroprevalence of SARS-CoV-2 Among Pediatric Healthcare Workers in Spain. Front Pediatr. 2020;8:547 Authors: Dacosta-Urbieta A, Rivero-Calle I, Pardo-Seco J, Redondo-Collazo L, Salas A, Gómez-Rial J, Martinón-Torres F Abstract Spain is one of the countries most severely affected by the SARS-CoV-2 pandemic, with almost 190,000 cases as of April 18, 2020. As healthcare workers (HCW) are one of the groups hardest hit by the infection, it is important...
Tue Oct 13, 2020 22:20
Bacterial Interference With Lactate Dehydrogenase Assay Leads to an Underestimation of Cytotoxicity.
Bacterial Interference With Lactate Dehydrogenase Assay Leads to an Underestimation of Cytotoxicity. Front Cell Infect Microbiol. 2020;10:494 Authors: Van den Bossche S, Vandeplassche E, Ostyn L, Coenye T, Crabbé A Abstract Models to study host-pathogen interactions in vitro are an important tool for investigating the infectious disease process and evaluating the efficacy of antimicrobial compounds. In these models, the viability of mammalian...
Tue Oct 13, 2020 22:20
ABCF1 Regulates dsDNA-induced Immune Responses in Human Airway Epithelial Cells. Front Cell Infect Microbiol. 2020;10:487 Authors: Cao QT, Aguiar JA, Tremblay BJ, Abbas N, Tiessen N, Revill S, Makhdami N, Ayoub A, Cox G, Ask K, Doxey AC, Hirota JA Abstract Background: The airway epithelium represents a critical component of the human lung that helps orchestrate defenses against respiratory tract viral infections, which are responsible for...
Tue Oct 13, 2020 22:20
Evaluation of Appropriateness and Cost Savings of Pharmacist-Driven Palivizumab Ordering. J Pediatr Pharmacol Ther. 2020;25(7):636-641 Authors: Weaver KL, Bondi DS, Shah PA, Bhagat PH Abstract OBJECTIVES: Guidelines by the AAP for the use of palivizumab prophylaxis for respiratory syncytial virus (RSV) recommend administration within 72 hours prior to discharge for selected high-risk patient populations. Our institution historically administered...
Tue Oct 13, 2020 22:20
Molecular detection of type III secretory toxins in Pseudomonas aeruginosa isolates. Cell Mol Biol (Noisy-le-grand). 2020 Jul 31;66(5):9-14 Authors: Jarjees KK Abstract Pseudomonas aeruginosa has been known as a common unscrupulous pathogen that reasons cause nosocomial infections in patients with immunocompromise. Infection with multi-drug resistant Pseudomonas aeruginosa infection in many patients is a public health problem. The bacterium...
Tue Oct 13, 2020 22:20
Immunopathological features of air pollution and its impact on inflammatory airway diseases (IAD). World Allergy Organ J. 2020 Oct;13(10):100467 Authors: Rouadi PW, Idriss SA, Naclerio RM, Peden DB, Ansotegui IJ, Canonica GW, Gonzalez-Diaz SN, Rosario Filho NA, Ivancevich JC, Hellings PW, Murrieta-Aguttes M, Zaitoun FH, Irani C, Karam MR, Bousquet J Abstract Air pollution causes significant morbidity and mortality in patients with inflammatory...
Tue Oct 13, 2020 23:35
A New Form of Irritant Rhinitis to Filtering Face-Piece Particle (FFP) Masks (FFP2/N95/KN95 Respirators) during COVID-19 Pandemic. World Allergy Organ J. 2020 Oct 06;:100474 Authors: Klimek L, Huppertz T, Alali A, Spielhaupter M, Hörmann K, Matthias C, Hagemann J Abstract Filtering facepiece particle (FFP) masks are important items of personal protective equipment in fighting COVID-19 pandemic. They shall protect the wearer of the mask from...
Tue Oct 13, 2020 23:35
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