Non-invasive imaging techniques to assess myocardial perfusion. Expert Rev Med Devices. 2020 Oct 12;: Authors: Villemain O, Baranger J, Jalal Z, Lam C, Calais J, Pernot M, Cifra B, Friedberg MK, Mertens L Abstract INTRODUCTION: Coronary artery disease affecting myocardial perfusion continues to be the leading cause of cardiovascular morbidity and mortality worldwide. While invasive evaluation based on coronary angiography and flow measurements...
Tue Oct 13, 2020 21:24
The impact of the COVID-19 pandemic on surgical management of breast cancer: global trends and future perspectives. Oncologist. 2020 Oct 12;: Authors: Rocco N, Montagna G, di Micco R, Benson J, Criscitiello C, Chen L, Di Pace B, Colmenarejo AJE, Harder Y, Karakatsanis A, Maglia A, Mele M, Nafissi N, Ferreira PS, Taher W, Tejerina A, Vinci A, Nava M, Catanuto G PMID: 33044007 [PubMed - as supplied by publisher]
Tue Oct 13, 2020 21:24
Adjuvant treatment for high-risk salivary gland malignancies and prognostic stratification based on a 20-year single institution experience. Health Sci Rep. 2020 Dec;3(4):e195 Authors: Onderdonk BE, Vokes EE, Gwede M, Blair E, Agrawal N, Haraf DJ Abstract Background and Aim: Retrospective analysis of the utility of adjuvant radiation (RT) or chemoradiation (CRT) and identify prognostic features for patients with high-risk head and neck salivary...
Tue Oct 13, 2020 21:24
Real-time transabdominal ultrasound-guided ERCP is feasible and effective in pregnancy: a case series. Endosc Int Open. 2020 Oct;8(10):E1504-E1507 Authors: Li S, Dargavel C, Muradali D, May GR, Mosko JD Abstract Background and study aims Endoscopic retrograde cholangiopancreatography (ERCP) is commonly required in pregnancy for choledocholithiasis, however, radiation exposure is a major concern for patients. Real-time transabdominal (TA)...
Tue Oct 13, 2020 21:24
Circulating Non-coding RNAs in Renal Cell Carcinoma-Pathogenesis and Potential Implications as Clinical Biomarkers. Front Cell Dev Biol. 2020;8:828 Authors: Barth DA, Drula R, Ott L, Fabris L, Slaby O, Calin GA, Pichler M Abstract Liquid biopsy-the determination of circulating cells, proteins, DNA or RNA from biofluids through a "less invasive" approach-has emerged as a novel approach in all cancer entities. Circulating non-(protein) coding...
Tue Oct 13, 2020 21:24
Multi-Cell Type Glioblastoma Tumor Spheroids for Evaluating Sub-Population-Specific Drug Response. Front Bioeng Biotechnol. 2020;8:538663 Authors: Sivakumar H, Devarasetty M, Kram DE, Strowd RE, Skardal A Abstract Glioblastoma (GBM) is a lethal, incurable form of cancer in the brain. Even with maximally aggressive surgery and chemoradiotherapy, median patient survival is 14.5 months. These tumors infiltrate normal brain tissue, are surgically...
Tue Oct 13, 2020 21:24
Tumor Microenvironment-Associated Immune-Related Genes for the Prognosis of Malignant Pleural Mesothelioma. Front Oncol. 2020;10:544789 Authors: Xu X, Cheng L, Fan Y, Mao W Abstract Malignant pleural mesothelioma (MPM) is a rare but highly aggressive thoracic malignancy. ESTIMATE algorithm-derived immune scores are commonly used to quantify the immune and stromal components in tumors. Thus, this algorithm may help determine the tumor microenvironment...
Tue Oct 13, 2020 21:24
The role of Aurora-A in human cancers and future therapeutics. Am J Cancer Res. 2020;10(9):2705-2729 Authors: Lin X, Xiang X, Hao L, Wang T, Lai Y, Abudoureyimu M, Zhou H, Feng B, Chu X, Wang R Abstract Aurora-A is a mitotic serine/threonine-protein kinase and an oncogene. In normal cells, Aurora-A appears from G2 phase and localizes at the centrosome, where it participates in centrosome replication, isolation and maturation. Aurora-A also...
Tue Oct 13, 2020 21:24
Overexpression of circRNA chr7:154954255-154998784+ in cancer-associated pancreatic stellate cells promotes the growth and metastasis of pancreatic cancer by targeting the miR-4459/KIAA0513 axis. Am J Transl Res. 2020;12(9):5048-5063 Authors: Shao F, Cai M, Fan FF, Huang M, Tao Y, Wang C, Meng FT, Huang Q Abstract PURPOSE: Circular RNAs (circRNAs) have been reported to act as important regulators in pancreatic cancer. Abnormal expression of...
Tue Oct 13, 2020 21:24
Sleep Inconsistency and Markers of Inflammation. Front Neurol. 2020;11:1042 Authors: Dzierzewski JM, Donovan EK, Kay DB, Sannes TS, Bradbrook KE Abstract Objective: Poor sleep is associated with higher levels of inflammatory biomarkers. Conventionally, higher average time awake, lower average time asleep, and lower sleep efficiency define poor sleep. Recent research suggests that, in addition to average sleep, sleep inconsistency is an important...
Tue Oct 13, 2020 21:24
Amsterdam International Consensus Meeting: tumor response scoring in the pathology assessment of resected pancreatic cancer after neoadjuvant therapy. Mod Pathol. 2020 Oct 12;: Authors: Janssen BV, Tutucu F, van Roessel S, Adsay V, Basturk O, Campbell F, Doglioni C, Esposito I, Feakins R, Fukushima N, Gill AJ, Hruban RH, Kaplan J, Koerkamp BG, Hong SM, Krasinskas A, Luchini C, Offerhaus J, Sarasqueta AF, Shi C, Singhi A, Stoop TF, Soer EC, Thompson E, van Tienhoven...
Tue Oct 13, 2020 21:24
Use of an ultrasound imaging device within the applicator to evaluate placement and support treatment planning for breast brachytherapy and intraoperative radiation therapy. Brachytherapy. 2020 Oct 08;: Authors: Unnikrishnan S, Brenin DR, Suralik G, Showalter TN, Shami V, Libby B, Watkins WT, Showalter SL, Zhao F, Govinahallisathyanarayana S, Hossack JA Abstract PURPOSE: We evaluated the use of ultrasound imaging within a brachytherapy applicator...
Tue Oct 13, 2020 21:24
Association of Consensus Molecular Subtypes and Molecular Markers With Clinical Outcomes in Patients With Metastatic Colorectal Cancer: Biomarker Analyses From LUME-Colon 1. Clin Colorectal Cancer. 2020 Sep 15;: Authors: Lenz HJ, Argiles G, Yoshino T, Tejpar S, Ciardiello F, Braunger J, Salnikov AV, Gabrielyan O, Schmid R, Höfler J, Kitzing T, Van Cutsem E Abstract INTRODUCTION: LUME-Colon 1 (NCT02149108) was a global, placebo-controlled phase...
Tue Oct 13, 2020 21:24
Older frail prehabilitated patients who cannot attain a 400 m 6-min walking distance before colorectal surgery suffer more postoperative complications. Eur J Surg Oncol. 2020 Oct 05;: Authors: Gillis C, Fenton TR, Gramlich L, Sajobi TT, Culos-Reed SN, Bousquet-Dion G, Elsherbini N, Fiore JF, Minnella EM, Awasthi R, Liberman AS, Boutros M, Carli F Abstract INTRODUCTION: Recent efforts to prehabilitate intermediately frail and frail (Fried frailty...
Tue Oct 13, 2020 21:24
An exploration of mercaptopurine/methotrexate tolerance during maintenance therapy in children with acute lymphoblastic leukemia. J Oncol Pharm Pract. 2020 Oct 12;:1078155220963550 Authors: Whiley AC, Price V, MacDonald T Abstract PURPOSE: Mercaptopurine (6MP) and methotrexate (MTX) cause myelosuppression and interruptions in therapy in children with lymphoblastic leukemia (ALL). Length of time off of therapy is related to poorer outcomes....
Tue Oct 13, 2020 21:24
Genomic characterization reveals potential biomarkers in nasopharyngeal carcinoma patients with relapse. Expert Rev Mol Diagn. 2020 Oct 12;: Authors: Cho WCS, Tse KP, Ngan RKC, Cheuk W, Ma VWS, Yang YT, Yip TTC, Tan KT, Chen SJ Abstract BACKGROUND: Although the majority of nasopharyngeal carcinoma (NPC) patients demonstrate favorable outcomes after radiotherapy and/or chemotherapy, about 8-10% of patients will develop recurrent disease, and...
Tue Oct 13, 2020 21:24
Analysis of Changes in Cancer-Related Fatigue of Breast Cancer Patients Receiving an Integrative Medicine Program. Integr Cancer Ther. 2020 Jan-Dec;19:1534735420963780 Authors: Schad F, Thronicke A, von Trott P, Oei SL Abstract INTRODUCTION: Cancer-related fatigue (CRF) occurs frequently in breast cancer patients. The aim of this real-world study was to analyze the longitudinal changes of CRF in breast cancer patients receiving an integrative...
Tue Oct 13, 2020 21:24
The Correlation Between Endolymphatic Hydrops and blood-labyrinth barrier Permeability of Meniere Disease. Ann Otol Rhinol Laryngol. 2020 Oct 13;:3489420964823 Authors: Zhang W, Xie J, Hui L, Li S, Zhang B Abstract OBJECTIVES: This study was designed to assess the correlation between the grades of endolymphatic hydrops and the blood-labyrinth barrier permeability in the affected ear in Meniere's disease, following the administration of...
Wed Oct 14, 2020 22:16
An Autopsy Case of TAFRO Syndrome with Type II Respiratory Failure. Am J Case Rep. 2020 Oct 13;21:e926721 Authors: Wada M, Nagata A, Kawashima A, Kagawa K Abstract BACKGROUND TAFRO syndrome (thrombocytopenia, anasarca, fever, myelofibrosis, renal dysfunction, and organomegaly) is a systemic inflammatory disorder. The histological features of TAFRO syndrome are not fully understood and few autopsy cases have been reported. CASE REPORT A 66-year-old...
Wed Oct 14, 2020 20:48
A Case of Fulminant Liver Failure in a 24-Year-Old Man with Coinfection with Hepatitis B Virus and SARS-CoV-2. Am J Case Rep. 2020 Oct 13;21:e925932 Authors: Ali E, Ziglam H, Kohla S, Ahmed M, Yassin M Abstract BACKGROUND Coronavirus disease 2019 (COVID-19) is a newly emerging disease that is still not fully characterized. It is caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), a novel virus that can be transmitted easily...
Wed Oct 14, 2020 20:48
Clavicle Shaft Fracture After Surgery for Bipolar Dislocation of the Clavicle. Am J Case Rep. 2020 Oct 12;21:e924889 Authors: Zou R, Wu M, Guan J Abstract BACKGROUND Bipolar dislocation of the clavicle is a rare disease that is often associated with some high-energy injuries. It refers to concomitant dislocation of the ipsilateral acromioclavicular joint and sternoclavicular joint. Because of its rarity, the diagnosis of bipolar dislocation...
Wed Oct 14, 2020 00:32
Widely Disseminated Cryptococcosis Manifesting in a Previously Undiagnosed Human Immunodeficiency Virus (HIV)-Positive 18-Year-Old. Am J Case Rep. 2020 Oct 12;21:e924410 Authors: Howard J, Thompson TZ, MacArthur RD, Rojiani AM, White J Abstract BACKGROUND After initial infection with HIV, loss of CD4+ T cells progresses along a predictable timeline. The clinical latency stage lasts an average of 10 years, until the CD4+ T cell count falls below...
Wed Oct 14, 2020 00:32
69 new pubmed citations were retrieved for your search. Click on the search hyperlink below to display the complete search results: "Front Oncol"[jour] These pubmed results were generated on 2020/10/13PubMed comprises more than millions of citations for biomedical literature from MEDLINE, life science journals, and online books. Citations may include links to full-text content from PubMed Central and publisher web sites.
Wed Oct 14, 2020 02:09
Endovascular treatment for spontaneous supraceliac isolated abdominal aortic dissection is a fabulous option. (Case report). Int J Surg Case Rep. 2020 Sep 19;76:227-230 Authors: Alhaizaey A, Azazy A, Khalil E, Joudat M, Alhazmi B Abstract Aortic dissection originates from isolated tear in the abdominal aorta is rare but potentially life or limb-threatening condition particularly if misdiagnosed. It may have a number of clinical presentations...
Wed Oct 14, 2020 22:36
Surgical approach for duodenal diverticulum perforation: A case report. Int J Surg Case Rep. 2020 Oct 03;76:217-220 Authors: Kansoun A, El-Helou E, Amiry AR, Bahmad M, Mohtar IA, Houcheimi F, Maanieh N, Hazim M, Rahal K, Atwi H, Ambriss W Abstract INTRODUCTION: Duodenal Diverticula is not uncommon and it is mostly found in the 2nd part of the duodenum. Despite the fact that it is mostly found incidentally, it can complicate however it rarely...
Wed Oct 14, 2020 22:36
Neurofibromatosis type 1 associated multiple and cystic gastrointestinal tumors: 02 case reports. Int J Surg Case Rep. 2020 Sep 19;76:210-216 Authors: Rahou FZ, Miry A, Bennani A, Bouziane M Abstract INTRODUCTION: GIST's are the most common mesenchymal tumor of the gastrointestinal tract, clinically and radiologically heterogeneous, only a histological study can confirm the diagnosis. The link between NF1 and GISTs have been established but...
Wed Oct 14, 2020 22:36
Extended-criteria uncontrolled DCD donor for a fragile recipient: A case report about a challenging yet successful lung transplantation. Int J Surg Case Rep. 2020 Sep 14;: Authors: Musso V, Mendogni P, Scaravilli V, Morlacchi LC, Croci GA, Palleschi A Abstract INTRODUCTION: Lung donation after circulatory death (DCD) has proved to be an effective strategy for expanding the donor pool, but is still considered challenging. We report a successful...
Wed Oct 14, 2020 22:36
Thoracic empyema after gallstone spillage in times of Covid. Int J Surg Case Rep. 2020;76:221-226 Authors: Tchercansky AN, Fernandez Alberti J, Panzardi N, Auvieux R, Buero A Abstract Introduction: Laparoscopic cholecystectomy has become the gold standard for gallbladder disease. Although gallbladder perforation and spilled gallstones during surgery are common complications, thoracic consequences are rare. Presentation of case: We...
Tue Oct 13, 2020 22:32
Left inferior epigastric artery injury in COVID-19 patient. Case report and literature review. Int J Surg Case Rep. 2020 Oct 04;: Authors: Bakirov I, Bakirova G, Albalawi Y, Asiri AY, Faqihi F, Bakirli I, Hammami D, Bakirli H, Mandow NM Abstract Introduction: Management of COVID-19 pneumonia cases is a medical challenge. However, the situation becomes worse if the patient has coexisting morbidities or newly developed complications. The study...
Tue Oct 13, 2020 22:32
Gastric perforation by intragastric balloon: Laparoscopic gastric wedge resection can be a strategy?
Gastric perforation by intragastric balloon: Laparoscopic gastric wedge resection can be a strategy? Int J Surg Case Rep. 2020 Sep 06;: Authors: Lucido FS, Scotti L, Scognamiglio G, Gambardella C, Brusciano L, Del Genio G, Pizza F, Ruggiero R, Parmeggiani D, Nesta G Abstract INTRODUCTION: IGB (Intragastric Balloon) is acknowledged to be a safe and secure device, whose outcomes in terms of weight loss are widely discussed. Bariatric community...
Tue Oct 13, 2020 22:32
Late rectal anastomotic leakage treated with diode laser FiLaC probe. A case report of a new minimal invasive treatment. Int J Surg Case Rep. 2020 Sep 08;: Authors: Terracciano G, Brusciano L, Gualtieri G, Gambardella C, Sturiale A, Lucido FS, Tolone S, Docimo L Abstract INTRODUCTION: Anastomotic Leakage (AL) is one of the most important early postoperative complication of the adenocarcinoma's surgical treatment. Fistula Laser Closure (FiLaC®)...
Tue Oct 13, 2020 22:32
The importance of patient' selection in bariatric surgery: One not fit for all. Case report of a preventable double severe complication after Laparoscopic gastric banding positioning. Int J Surg Case Rep. 2020 Sep 06;: Authors: Lucido FS, Giuseppe S, Alessandro S, Claudio G, Luigi B, Del Genio G, Francesco P, Domenico P, Simona P, Mariachiara LV Abstract INTRODUCTION: Laparoscopic adjustable gastric banding (LAGB) is a minimal invasive, effective...
Tue Oct 13, 2020 22:32
Robotic approach to large tailgut cyst with malignant transformation: A case report. Int J Surg Case Rep. 2020 Sep 24;: Authors: Marano A, Giuffrida MC, Peluso C, Testa V, Bosio P, Borghi F Abstract INTRODUCTION: Tailgut cysts (TGC) are rare congenital retrorectal lesions deriving from vestiges of the hindgut. The risk of malignant transformation is relatively high. Thus early diagnosis and a complete removal of the mass are of paramount importance....
Tue Oct 13, 2020 22:32
Single staged hybrid approach for multilevel aortic-iliac-femoral-popliteal disease. Int J Surg Case Rep. 2020 Sep 22;: Authors: Dinoto E, Pecoraro F, Cutrupi A, Bracale UM, Panagrosso M, Bajardi G Abstract INTRODUCTION: Multilevel peripheral arterial disease (MPAD) is the main cause of critic limb ischemia (CLI). Vascular interventions are required to increase distal blood flow and reduce the risk of lower limb amputation. PRESENTATION...
Tue Oct 13, 2020 22:32
Small bowel volvulus due to a large intestinal lipoma: A rare case report. Int J Surg Case Rep. 2020 Sep 25;: Authors: Di Buono G, Ricupati F, Amato G, Gulotta L, Romano G, Agrusa A Abstract INTRODUCTION: A lipoma of the small bowel mesentery is a uncommon clinical entity. It rarely causes obstruction and volvulus of the small bowel. CASE REPORT: A 63 year old man was admitted to the emergency department with acute abdominal pain....
Tue Oct 13, 2020 22:32
Impact of previous thoracsic radiation therapy on the efficacy of immune checkpoint inhibitors in advanced non-smasll-cell lung cancer. Jpn J Clin Oncol. 2020 Oct 14;: Authors: Hosokawa S, Ichihara E, Bessho A, Harada D, Inoue K, Shibayama T, Kishino D, Harita S, Ochi N, Oda N, Hara N, Hotta K, Maeda Y, Kiura K Abstract OBJECTIVES: Studies investigating the association between radiation therapy and the efficacy of immune checkpoint inhibitors...
Wed Oct 14, 2020 20:19
Uniform infection screening allowed safe head and neck surgery during the coronavirus disease 2019 pandemic in Japan. Jpn J Clin Oncol. 2020 Oct 13;: Authors: Ito A, Kobayashi K, Shiotsuka M, Sato T, Omura G, Matsumoto Y, Ikeda A, Sakai A, Eguchi K, Takano T, Matsumoto F, Kobayashi O, Iwata S, Yoshimoto S Abstract BACKGROUND: The purpose of this study was to determine whether a uniform infection screening protocol could be used to safely perform...
Wed Oct 14, 2020 20:19
Velcro Ties in Early Postoperative Pediatric Tracheostomy Care: A Systematic Review and Meta-analysis. Otolaryngol Head Neck Surg. 2020 Oct 13;:194599820964727 Authors: Chang BA, Gurberg J, Ware E, Luu K Abstract OBJECTIVE: To systematically review the literature to determine the difference in complications between standard twill and Velcro ties following pediatric tracheostomy. DATA SOURCES: MEDLINE, Embase, the Cochrane Database...
03:05
Association Between the Duration of Hearing Loss and Hearing Outcomes in Surgery for Otosclerosis. Otolaryngol Head Neck Surg. 2020 Oct 13;:194599820964726 Authors: Luryi AL, Schettino A, Babu SC, Bojrab DI, Michaelides EM, Bojrab DI, Schutt CA Abstract INTRODUCTION: Hearing loss due to otosclerosis is effectively treated with surgery. The association between duration of hearing loss and surgical outcomes is unknown. STUDY DESIGN:...
03:05
Myringoplasty With an Ultrathin Cartilage-Perichondrium Complex Graft Versus Temporalis Fascia Graft: A Propensity Score-Matched Analysis. Otolaryngol Head Neck Surg. 2020 Oct 13;:194599820965940 Authors: Huang YB, Hu LL, Ren DD, Han Z Abstract OBJECTIVE: To compare endoscopic myringoplasty using the cartilage-perichondrium complex as a graft (test group) with temporalis fascia microscopic myringoplasty (control group). STUDY...
03:05
In-Practice Endocrine Surgery Fellowship: A Novel Training Model. Otolaryngol Head Neck Surg. 2020 Oct 13;:194599820962791 Authors: Tierney HT, Eldeiry LS, Garber JR, Haddad CA, Varvares MA, Iannuzzi RA, Randolph GW Abstract OBJECTIVE: Endocrine surgery is an expanding field within otolaryngology. We hypothesized that a novel endocrine surgery fellowship model for in-practice otolaryngologists could result in expert-level training. ...
03:05
Clinical Radiographic Predictors of Response to Hypoglossal Nerve Stimulation for Obstructive Sleep Apnea. Otolaryngol Head Neck Surg. 2020 Oct 13;:194599820963141 Authors: Lee CH, Seay EG, Reese JW, Wu X, Schwab RJ, Keenan B, Dedhia RC Abstract OBJECTIVE: To determine if clinically acquired cephalometric measurements, specifically soft palate size, can predict hypoglossal nerve stimulation outcomes. STUDY DESIGN: Combined prospective...
03:05
Idiopathic Subglottic Stenosis: An Institutional Review of Outcomes With a Multimodality Surgical Approach. Otolaryngol Head Neck Surg. 2020 Oct 13;:194599820966978 Authors: Dwyer CD, Qiabi M, Fortin D, Inculet RI, Nichols AC, MacNeil SD, Malthaner R, Yoo J, Fung K Abstract OBJECTIVES: This article reports on a unique cohort of patients with idiopathic subglottic stenosis spilt fairly equally between endoscopic and open surgical approaches....
03:05
Self-perceived Taste and Flavor Perception: Associations With Quality of Life in Patients With Olfactory Loss. Otolaryngol Head Neck Surg. 2020 Oct 13;:194599820965242 Authors: Liu DT, Besser G, Prem B, Sharma G, Speth MM, Sedaghat AR, Mueller CA Abstract OBJECTIVE: To evaluate associations between self-perceived chemosensory functions of smell, taste, and flavor perception with olfactory-specific quality of life (QoL) in patients with...
03:05
Can Computed Tomography Findings Predict the Recurrence of Sinonasal Inverted Papilloma? Otolaryngol Head Neck Surg. 2020 Oct 13;:194599820964798 Authors: Glikson E, Dragonetti A, Soudry E, Rozendoren N, Landsberg R, Bedrin L, Mozzanica F, Schneider S, Yakirevitch A Abstract OBJECTIVE: To evaluate the correlation between the ability to predict the attachment site of sinonasal inverted papilloma by computed tomography and the long-term...
03:05
Oral Intubation Attempts in Patients With a Laryngectomy: A Significant Safety Threat. Otolaryngol Head Neck Surg. 2020 Oct 13;:194599820960728 Authors: Brenner MJ, Cramer JD, McGrath BA, Balakrishnan K, Stepan KO, Pandian V, Roberson DW, Shah RK, Chen AY, Brook I, Nussenbaum B Abstract It is impossible to secure the airway of a patient with "neck-only" breathing transorally or transnasally. Surgical removal of the larynx (laryngectomy)...
03:05
Clinical Predictors of Facial Nerve Outcomes After Surgical Resection of Vestibular Schwannoma. Otolaryngol Head Neck Surg. 2020 Oct 13;:194599820961389 Authors: Ren Y, MacDonald BV, Tawfik KO, Schwartz MS, Friedman RA Abstract OBJECTIVE: To identify clinical predictors of facial nerve (FN) outcomes after microsurgical resection of vestibular schwannoma (VS). STUDY DESIGN: Prospective cohort study. SETTING: Academic...
03:05
Shared Surgical Decision Making in the Era of COVID-19: Lessons From Hurricane Katrina. Otolaryngol Head Neck Surg. 2020 Oct 13;:194599820957277 Authors: Erbele ID, Arriaga MA, Nuss DW Abstract The COVID-19 pandemic has challenged every surgical discipline. Lessons learned from Hurricane Katrina have informed our department's management of the current crisis. That experience impressed upon us a profound appreciation for shared decision...
03:05
Olfactory Cleft Measurements and COVID-19-Related Anosmia. Otolaryngol Head Neck Surg. 2020 Oct 13;:194599820965920 Authors: Altundag A, Yıldırım D, Tekcan Sanli DE, Cayonu M, Kandemirli SG, Sanli AN, Arici Duz O, Saatci O Abstract OBJECTIVE: This study aimed to investigate the differences in olfactory cleft (OC) morphology in coronavirus disease 2019 (COVID-19) anosmia compared to control subjects and postviral anosmia related to infection...
03:05
Orally Inhaled Drug Particle Transport in Computerized Models of Laryngotracheal Stenosis. Otolaryngol Head Neck Surg. 2020 Oct 13;:194599820959674 Authors: Frank-Ito DO, Cohen SM Abstract OBJECTIVE: Adjuvant management for laryngotracheal stenosis (LTS) may involve inhaled corticosteroids, but metered dose inhalers are designed for pulmonary drug delivery. Comprehensive analyses of drug particle deposition efficiency for orally inhaled...
03:05
Prioritizing Diversity in Otolaryngology-Head and Neck Surgery: Starting a Conversation. Otolaryngol Head Neck Surg. 2020 Oct 13;:194599820960722 Authors: Truesdale CM, Baugh RF, Brenner MJ, Loyo M, Megwalu UC, Moore CE, Paddock EA, Prince ME, Strange M, Sylvester MJ, Thompson DM, Valdez TA, Xie Y, Bradford CR, Taylor DJ Abstract Academic centers embody the ideals of otolaryngology and are the specialty's port of entry. Building a diverse...
03:05
Peptide and pseudo-peptide (PSMA) Cu-64 radiopharmaceuticals. Q J Nucl Med Mol Imaging. 2020 Oct 12;: Authors: Mirzaei S, Lipp RW Abstract In recent years, the introduction of theranostic twins for specific diagnosis and treatment in patients with neuroendocrine tumors became a nuclear medicine success story. 64Cu/18F labeled prostate specific membrane antigen (PSMA) for molecular imaging with PET-CT and peptide radioligand therapy with 177Lu...
Wed Oct 14, 2020 20:27
64Cu-immunoPET imaging: bench to bedside. Q J Nucl Med Mol Imaging. 2020 Oct 12;: Authors: Natarajan A Abstract Positron emission tomography (PET) is a growing non-invasive diagnostic and molecular imaging tool in nuclear medicine, that is used to identify several diseases including cancer. The immunoPET probe is made up of monoclonal antibodies (mAbs) or its fragments or similar molecules that tagged with positron radioisotopes (68Ga, 64Cu,...
Wed Oct 14, 2020 20:27
Double Burden of Excess Weight and Anemia in Latin American Children up to 2019. Tohoku J Exp Med. 2020;252(2):159-168 Authors: Shimabuku RL, Delgado CA, Nakachi G, Teruya AA, Velasquez PM Abstract The double burden of malnutrition is the coexistence of two different conditions, mainly reflected as excess or deficit in weight. Anemia is a specific nutritional deficit not always included in the double burden assessment. We reviewed overweight...
Wed Oct 14, 2020 01:13
Pediatric Primary Hyperparathyroidism: Experience in a Tertiary Care Referral Center in a Developing Country Over Three Decades. World J Surg. 2020 Oct 12;: Authors: Sharanappa V, Mishra A, Bhatia V, Mayilvagnan S, Chand G, Agarwal G, Agarwal A, Mishra SK Abstract BACKGROUND: There is limited experience in managing pediatric primary hyperparathyroidism (PHPT). The aim of this study was to analyze the clinical presentation and outcome of surgery...
02:16
Letter to the Editor: Use of Direct Liver Stiffness Measurement in Evaluating the Severity of Liver Cirrhosis in Patients with Hepatocellular Carcinoma. World J Surg. 2020 Oct 11;: Authors: Pesce A, Feo CV PMID: 33043384 [PubMed - as supplied by publisher]
Tue Oct 13, 2020 21:50
Peri-operative Mortality Following Cholecystectomy in Australia: Potential Preventability of Adverse Events. World J Surg. 2020 Oct 11;: Authors: Mansour LT, Brien S, Reid J, Maddern GJ Abstract BACKGROUND: Cholecystectomy is a commonly performed procedure; however, it is not without risks. It is crucial to constantly audit surgical outcomes in order to improve quality of care. The aim of this retrospective population-based cohort study is...
Tue Oct 13, 2020 21:50
Primary spinal intradural extramedullary mesenchymal chondrosarcoma: a case report. World Neurosurg. 2020 Oct 10;: Authors: Saito R, Senbokuya N, Yagi T, Yoshioka H, Kanemaru K, Kinouchi H PMID: 33049384 [PubMed - as supplied by publisher]
Wed Oct 14, 2020 22:44
Application of CT imaging in diagnosis of endocrine nerve of gastric cancer and nursing intervention effect. World Neurosurg. 2020 Oct 10;: Authors: Qian Z, Wang J Abstract This article analyses some parameters and characteristics of CT images on gastric cancer patients, and discusses the application of CT images in the diagnosis of gastric cancer endocrine nerves and the impact of nursing intervention on the quality and mental state of CT...
Wed Oct 14, 2020 22:44
Risk Factors for Cerebral Vasospasm in Aneurysmal Subarachnoid Hemorrhage: A Population-Based Study of 8,346 Patients. World Neurosurg. 2020 Oct 10;: Authors: Rumalla K, Lin M, Ding L, Gaddis M, Giannotta S, Attenello F, Mack W Abstract BACKGROUND: A recent systematic review and meta-analysis found there was a lack of consensus regarding risk factors for cerebral vasospasm in aneurysmal subarachnoid hemorrhage (aSAH). OBJECTIVE: To...
Wed Oct 14, 2020 22:44
Efficiency of endovascular therapy for bilateral cavernous sinus dural arteriovenous fistula. World Neurosurg. 2020 Oct 10;: Authors: Churojana A, Sakarunchai I, Aurboonyawat T, Chankaew E, Withayasuk P, Sangpetngam B Abstract BACKGROUND: The principles of endovascular treatment of bilateral cavernous sinus dural arteriovenous fistula (CS-dAVF) are not well established due to the complexity in the number of fistula tracts and their behavior...
Wed Oct 14, 2020 22:44
Purely intra-foraminal meningioma in the cervical spine. World Neurosurg. 2020 Oct 10;: Authors: Pommier B, Vasiljevic A, Barrey C Abstract Meningiomas are mostly benign intradural tumours. Concerning the spine, some of them can extend outside the canal or even develop extradurally but their primary attach is often located in the vertebral canal. Here we present the case of an exceptional purely intra-foraminal meningioma mimicking neurogenic...
Wed Oct 14, 2020 22:44
Revisiting the Vertebral Venous Plexus- A Comprehensive Review of the Literature. World Neurosurg. 2020 Oct 10;: Authors: Carpenter K, Decater T, Iwanaga J, Maulucci CM, Bui CJ, Dumont AS, Tubbs RS Abstract The venous drainage of the vertebral and paravertebral regions is important for a better understanding of hematogenous disease spread. Moreover, the spine surgeon must be well acquainted with this anatomy in order to minimize intra and postoperative...
Wed Oct 14, 2020 22:44
Critical Evaluation of Interventional Neuroradiology Fellowship Program Websites in North America. World Neurosurg. 2020 Oct 09;: Authors: Vilanilam GK, Wadhwa V, Purushothaman R, Desai S, Kamran M, Radvany MG Abstract OBJECTIVE: To investigate the accessibility and content of interventional neuroradiology fellowship program websites in North America. METHODS: We obtained a list of interventional neuroradiology/endovascular surgical...
Tue Oct 13, 2020 22:17
Patient Satisfaction with Neurosurgery Telemedicine Visits During the COVID-19 Pandemic: A Prospective Cohort Study. World Neurosurg. 2020 Oct 09;: Authors: Yoon EJ, Tong D, Anton GM, Jasinski JM, Claus CF, Soo TM, Kelkar PS PMID: 33045455 [PubMed - as supplied by publisher]
Tue Oct 13, 2020 22:17
Case Report of Transgender Patient with Gonadotropic Dysfunction Secondary to Craniopharyngioma: Towards Improving Understanding of Biopsychosocial Dynamics of Gender Identity in Neurosurgical Care. World Neurosurg. 2020 Oct 09;: Authors: Emmert AS, Hussein AE, Slobodian O, Krueger B, Bhabhra R, Hagen MC, Pickle S, Forbes J Abstract BACKGROUND: There is a paucity of information in the literature linking possible neuroendocrinologic repercussions...
Tue Oct 13, 2020 22:17
The potential risk of thoracic aorta injury from excessively long right pedicle screws in patients with left thoracic scoliosis: a CT image study. World Neurosurg. 2020 Oct 09;: Authors: Zhang T, Qiu Y, Zhu Z, Yu Y, Wang B, Jiang J Abstract OBJECTIVE: To investigate the changed position of thoracic aorta relative to spine in patients with left thoracic scoliosis and to analyze the potential risks of thoracic aorta injury from pedicle screw...
Tue Oct 13, 2020 22:17
Blast-induced Traumatic Brain Injuries: Experience from the Deadliest Suicide Double-Car Bomb Attack in Iraq. World Neurosurg. 2020 Oct 09;: Authors: Hoz SS, Al-Sharshahi ZF, Dolachee AA, Al-Smaysim AM, Matti WE, Bydon A, Kadhum HJ Abstract INTRODUCTION: Blast-induced traumatic brain injuries (bTBIs) are increasingly frequent in civilian settings. The authors present the first study of bTBI victims in Iraq. The paper focuses on one of the deadliest...
Tue Oct 13, 2020 22:17
Introducing the Rupture Criticality Index to Compare Risk Factor Combinations Associated with Aneurysmal Rupture. World Neurosurg. 2020 Oct 09;: Authors: Malik KM, Krishnamurthy M, Alam F, Zakaria H, Malik G Abstract BACKGROUND: Relative risk is insufficient to guide treatment decision making for unruptured intracranial aneurysms. OBJECTIVE: To introduce a novel risk assessment methodology called Rupture Criticality Index (RCI), which...
Tue Oct 13, 2020 22:17
Emergent carotid artery stenting following intravenous alteplase infusion after rapid negative diagnosis for COVID-19 by loop-mediated isothermal amplification assay: A case report. World Neurosurg. 2020 Oct 09;: Authors: Michiwaki Y, Tanaka T, Wakamiya T, Tabei Y, Samura K, Suehiro E, Kawashima M Abstract BACKGROUND: During the coronavirus disease 2019 (COVID-19) pandemic, a rapid screening method for COVID-19 detection is needed to decide...
Tue Oct 13, 2020 22:17
Trigeminal Neuralgia Caused by Vascular Compression from the Petrous Carotid Artery with Bony Erosion and Meckel's Cave Encephalocele: Clinical Imaging with Surgical Video. World Neurosurg. 2020 Oct 09;: Authors: Erginoglu U, Sayyahmelli S, Baskaya MK Abstract Trigeminal neuralgia (TN) is most commonly caused by neurovascular compression of the superior cerebellar artery. We present the first reported TN case where nerve compression was caused...
Tue Oct 13, 2020 22:17
[Mitochondrial encephalopathy, lactic acidosis and stroke-like episodes / myoclonus epilepsy with ragged-red fibers /Leigh overlap syndrome caused by mitochondrial DNA 8344A>G mutation]. Beijing Da Xue Xue Bao Yi Xue Ban. 2020 Oct 18;52(5):851-855 Authors: Hou Y, Zhao XT, Xie ZY, Yuan Y, Wang ZX Abstract OBJECTIVE: Mitochondrial deoxyribonucleic acid (mtDNA) 8344 A>G (m.8344A>G) mutation is the common mutation associated with mitochondrial...
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In vitro evaluation of Annona muricata L. (Soursop) leaf methanol extracts on inhibition of tumorigenicity and metastasis of breast cancer cells. Biomarkers. 2020 Oct 13;:1-25 Authors: Naik AV, Sellappan K Abstract Purpose: The present study evaluates the in-vitro anti-tumorigenic potential of leaf methanol extracts of A. muricata (LMAM). Materials and methods: The cytotoxic activity was assessed in MCF-7 cells by MTT assay at various...
Wed Oct 14, 2020 20:52
Biogenic silver/silver chloride nanoparticles inhibit human glioblastoma stem cells growth in vitro and Ehrlich ascites carcinoma cell growth in vivo. J Cell Mol Med. 2020 Oct 13;: Authors: Kabir SR, Dai Z, Nurujjaman M, Cui X, Asaduzzaman AKM, Sun B, Zhang X, Dai H, Zhao X Abstract The importance of biogenic silver/silver chloride nanoparticles has become increasing day by day. In the present study, silver/silver chloride nanoparticles...
Wed Oct 14, 2020 20:52
Pterostilbene enhances sorafenib's anticancer effects on gastric adenocarcinoma. J Cell Mol Med. 2020 Oct 13;: Authors: Zhao T, Wang C, Huo X, He ML, Chen J Abstract Sorafenib has been approved for the treatment of certain cancers in clinic. However, the effects of sorafenib on gastric adenocarcinoma (GAC) were still limited. This study aimed to evaluate both in vitro and in vivo efficacy of sorafenib in combination with pterostilbene...
Wed Oct 14, 2020 20:52
[Effects of salinomycin on proliferation and apoptosis of oral squamous cell carcinoma]. Beijing Da Xue Xue Bao Yi Xue Ban. 2020 Oct 18;52(5):902-906 Authors: Su LZ, Chen J, Li X, Ji P Abstract OBJECTIVE: To investigate the effects of salinomycin on the proliferation and apoptosis of oral squamous carcinoma cells and to further understand the mechanisms of these effects. METHODS: The human oral squamous carcinoma cell line CAL-27...
Wed Oct 14, 2020 20:52
Histone mRNA is subject to 3´ uridylation and re-adenylation in Aspergillus nidulans. Mol Microbiol. 2020 Oct 12;: Authors: Mossanen-Parsi A, Parisi D, Browne-Marke N, Bharudin I, Connell SR, Mayans O, Fucini P, Morozov IY, Caddick MX Abstract The role of post-transcriptional RNA modification is of growing interest. One example is the addition of non-templated uridine residues to the 3´ end of transcripts. In mammalian systems uridylation...
Wed Oct 14, 2020 20:52
Curcumin induces G2/M arrest and triggers autophagy, ROS generation and cell senescence in cervical cancer cells. J Cancer. 2020;11(22):6704-6715 Authors: Wang T, Wu X, Al Rudaisat M, Song Y, Cheng H Abstract Our study explored the tumor-suppressive effect of curcumin on cervical cancer cells. Cervical cancer is one of the most common cancers among women worldwide. Acquired resistance to chemotherapeutics and toxicity of such drugs has...
Wed Oct 14, 2020 20:52
Overexpression of KIAA0101 Promotes the Progression of Non-small Cell Lung Cancer. J Cancer. 2020;11(22):6663-6674 Authors: Cao H, Zheng J, Yao Y, Yang Q, Yan R, Sun W, Ruan K, Zhou J, Zhou J Abstract Lung cancer is the leading cause of cancer related death worldwide, with a continue-rising incidence. The proliferating cell nuclear antigen binding protein KIAA0101 is highly expressed in various types of cancer, including non-small cell...
Wed Oct 14, 2020 20:52
Cell cycle control and environmental response by second messengers in Caulobacter crescentus. BMC Bioinformatics. 2020 Sep 30;21(Suppl 14):408 Authors: Xu C, Weston BR, Tyson JJ, Cao Y Abstract BACKGROUND: Second messengers, c-di-GMP and (p)ppGpp, are vital regulatory molecules in bacteria, influencing cellular processes such as biofilm formation, transcription, virulence, quorum sensing, and proliferation. While c-di-GMP and (p)ppGpp are...
Wed Oct 14, 2020 20:52
Related Articles Bi-allelic Mutations in M1AP Are a Frequent Cause of Meiotic Arrest and Severely Impaired Spermatogenesis Leading to Male Infertility. Am J Hum Genet. 2020 08 06;107(2):342-351 Authors: Wyrwoll MJ, Temel ŞG, Nagirnaja L, Oud MS, Lopes AM, van der Heijden GW, Heald JS, Rotte N, Wistuba J, Wöste M, Ledig S, Krenz H, Smits RM, Carvalho F, Gonçalves J, Fietz D, Türkgenç B, Ergören MC, Çetinkaya M, Başar M, Kahraman S, McEleny K, Xavier MJ, Turner...
Wed Oct 14, 2020 20:52
Related Articles Bi-allelic Missense Pathogenic Variants in TRIP13 Cause Female Infertility Characterized by Oocyte Maturation Arrest. Am J Hum Genet. 2020 07 02;107(1):15-23 Authors: Zhang Z, Li B, Fu J, Li R, Diao F, Li C, Chen B, Du J, Zhou Z, Mu J, Yan Z, Wu L, Liu S, Wang W, Zhao L, Dong J, He L, Liang X, Kuang Y, Sun X, Sang Q, Wang L Abstract Normal oocyte meiosis is a prerequisite for successful human reproduction, and abnormalities...
Wed Oct 14, 2020 20:52
Related Articles ADAR1: "Editor-in-Chief" of Cytoplasmic Innate Immunity. Front Immunol. 2019;10:1763 Authors: Lamers MM, van den Hoogen BG, Haagmans BL Abstract Specialized receptors that recognize molecular patterns such as double stranded RNA duplexes-indicative of viral replication-are potent triggers of the innate immune system. Although their activation is beneficial during viral infection, RNA transcribed from endogenous mobile genetic...
Wed Oct 14, 2020 20:52
Related Articles TREM1/3 Deficiency Impairs Tissue Repair After Acute Kidney Injury and Mitochondrial Metabolic Flexibility in Tubular Epithelial Cells. Front Immunol. 2019;10:1469 Authors: Tammaro A, Scantlebery AML, Rampanelli E, Borrelli C, Claessen N, Butter LM, Soriani A, Colonna M, Leemans JC, Dessing MC, Florquin S Abstract Long-term sequelae of acute kidney injury (AKI) are associated with incomplete recovery of renal function and...
Wed Oct 14, 2020 20:52
Related Articles Long noncoding RNA PVT1: A highly dysregulated gene in malignancy. J Cell Physiol. 2020 02;235(2):818-835 Authors: Ghafouri-Fard S, Omrani MD, Taheri M Abstract Recent studies have verified the contribution of several long noncoding RNAs (lncRNAs) in the carcinogenesis. Among the highly acknowledged lncRNAs is the human homolog of the plasmacytoma variant translocation gene, which is called PVT1. PVT1 resides near Myc oncogene...
Wed Oct 14, 2020 20:52
Related Articles Human cytomegaloviral multifunctional protein kinase pUL97 impairs zebrafish embryonic development and increases mortality. Sci Rep. 2019 05 10;9(1):7219 Authors: Cazorla-Vázquez S, Steingruber M, Marschall M, Engel FB Abstract Cytomegalovirus is a worldwide-distributed human pathogen, which is the leading cause of congenital virus infection, affecting 0.5 to 2% of live births. To date, it is largely unclear which molecular...
Wed Oct 14, 2020 20:52
Nanoparticle-delivered miriplatin ultrasmall dots suppress triple negative breast cancer lung metastasis by targeting circulating tumor cells. J Control Release. 2020 Oct 09;: Authors: Li Y, Qian D, Lin HP, Xie J, Yang P, Maddy D, Xiao Y, Huang X, Wang Z, Yang C Abstract No effective therapy is yet available to treat triple negative breast cancer (TNBC), which has poor prognosis due to frequent metastasis. Cancer stem cells (CSCs) or CSC-like...
Tue Oct 13, 2020 21:59
Ganoderma tsugae suppresses the proliferation of endometrial carcinoma cells via Akt signaling pathway. Environ Toxicol. 2020 Oct 12;: Authors: Tsai YT, Kuo PH, Kuo HP, Hsu CY, Lee YJ, Kuo CL, Liu JY, Lee SL, Kao MC Abstract Ganoderma is one of the common medicinal mushrooms in traditional Chinese medicine. Previous researches have unveiled the multifaceted biological activity of Ganoderma extract. Ganoderma tsugae has been investigated...
Tue Oct 13, 2020 21:59
Latcripin-7A, derivative of Lentinula edodes C91-3, reduces migration and induces apoptosis, autophagy, and cell cycle arrest at G1 phase in breast cancer cells. Appl Microbiol Biotechnol. 2020 Oct 12;: Authors: Din SRU, Zhong M, Nisar MA, Saleem MZ, Hussain A, Khinsar KH, Alam S, Ayub G, Kanwal S, Li X, Zhang W, Wang X, Ning A, Cao J, Huang M Abstract Due to the high mortality rate and an increase in breast cancer incidence, it has been...
Tue Oct 13, 2020 21:59
Immunoexpression of Apoptosis and Cell-cycle Arrest Markers in Oral Lichen Planus. Appl Immunohistochem Mol Morphol. 2020 Oct 09;: Authors: Pérez-Sayáns M, Lorenzo-Pouso AI, Chamorro-Petronacci CM, Suárez-Peñaranda JM, Padín-Iruegas E, González-Moles MA, Marichalar-Mendía X, García-García A, Blanco-Carrión A Abstract The expression pattern of a panel of 5 molecular markers (p53, cyclin D1, Ki-67, BCL-2, and BAX) was studied in samples...
Tue Oct 13, 2020 21:59
Homo- and hetero-dinuclear Pt(II)/Pd(II) complexes: studies of hydrolysis, nucleophilic substitution reactions, DNA/BSA interactions, DFT calculations, molecular docking and cytotoxic activity. Dalton Trans. 2020 Oct 12;: Authors: Ćoćić D, Jovanović-Stević S, Jelić R, Matić S, Popović S, Djurdjević P, Baskić D, Petrović B Abstract Three dinuclear complexes [Pd2(tpbd)Cl2]Cl2 (PP1), [Pt2(tpbd)Cl2]Cl2 (PP2) and [PdPt(tpbd)Cl2]Cl2 (PP3) (tpbd...
Tue Oct 13, 2020 21:59
C21 Fraction Refined from Marsdenia tenacissima-Induced Apoptosis is Enhanced by Suppression of Autophagy in Human Gastric Cell Lines. ACS Omega. 2020 Oct 06;5(39):25156-25163 Authors: Li K, Hao K, Zhang Y, Xu A, Wang Q, Du Y, Wu L, Chen B, Zhang W, Wang Z Abstract C21 steroidal glycosides have been extensively reported for treating several types of cancer and are widely found in Marsdenia tenacissima. In this study, a C21 fraction was synthesized...
Tue Oct 13, 2020 21:59
Moderate Fever Cycles as a Potential Mechanism to Protect the Respiratory System in COVID-19 Patients. Front Med (Lausanne). 2020;7:564170 Authors: Guihur A, Rebeaud ME, Fauvet B, Tiwari S, Weiss YG, Goloubinoff P Abstract Mortality in COVID-19 patients predominantly results from an acute respiratory distress syndrome (ARDS), in which lungs alveolar cells undergo programmed cell death. Mortality in a sepsis-induced ARDS rat model is reduced...
Tue Oct 13, 2020 21:59
Protein Lysine Acetylation in Ovarian Granulosa Cells Affects Metabolic Homeostasis and Clinical Presentations of Women With Polycystic Ovary Syndrome. Front Cell Dev Biol. 2020;8:567028 Authors: Min Z, Long X, Zhao H, Zhen X, Li R, Li M, Fan Y, Yu Y, Zhao Y, Qiao J Abstract Polycystic ovary syndrome (PCOS) is one of the most common reproductive endocrine disorders accompanied by obvious metabolic abnormalities. Lower-quality oocytes and embryos...
Tue Oct 13, 2020 21:59
miR-4270 regulates cell proliferation and apoptosis in patients with Sertoli cell-only syndrome by targeting GADD45A and inactivating the NOTCH signaling pathway. Am J Transl Res. 2020;12(9):5730-5740 Authors: Wang H, Huang Z, Zhao X, Guo B, Ji Z Abstract In recent decades, growing data has suggested that microRNAs (miRNAs, miRs) play a critical role in the development of Sertoli cells (SC), including regulating SC maturation, synthesis, proliferation,...
Tue Oct 13, 2020 21:59
Comprehensive analysis of core genes and key pathways in Parkinson's disease. Am J Transl Res. 2020;12(9):5630-5639 Authors: Yuan Q, Zhang S, Li J, Xiao J, Li X, Yang J, Lu D, Wang Y Abstract Parkinson's disease (PD) is a neurodegenerative disease that occurs mostly in middle-aged and older adults. Its main pathological feature is the progressive death of substantia nigra dopaminergic neurons. As the world's population ages, the number of...
Tue Oct 13, 2020 21:59
Deubiquitinase PSMD7 regulates cell fate and is associated with disease progression in breast cancer. Am J Transl Res. 2020;12(9):5433-5448 Authors: Zhao Y, Yang X, Xu X, Zhang J, Zhang L, Xu H, Miao Z, Li D, Wang S Abstract Breast cancer is the most common malignant tumor and the leading cause of cancer-related death in women. The ubiquitin-proteasome system regulates the stability of most proteins controlling various biological processes...
Tue Oct 13, 2020 21:59
Lycorine inhibits tumor growth of human osteosarcoma cells by blocking Wnt/β-catenin, ERK1/2/MAPK and PI3K/AKT signaling pathway. Am J Transl Res. 2020;12(9):5381-5398 Authors: Yuan XH, Zhang P, Yu TT, Huang HK, Zhang LL, Yang CM, Tan T, Yang SD, Luo XJ, Luo JY Abstract Osteosarcoma (OS) is the most common type of primary bone cancer. Even with advances in early diagnosis and aggressive treatment, the overall prognosis for OS remains to be...
Tue Oct 13, 2020 21:59
microRNA-133b represses the progression of lung cancer through inhibiting SOX9/β-catenin signaling pathway. Int J Clin Exp Pathol. 2020;13(9):2270-2279 Authors: Liu S, Li S, Yu X, Wang Q, Sun H Abstract MicroRNA-133b (miR-133b) has been shown to be down-regulated in lung cancer and functions as a tumor repressor. However, the underlying mechanisms of miR-133b in lung cancer are not clear. SOX9, a member of SOX family, serves as an oncogene...
Tue Oct 13, 2020 21:59
New Insights Into the Role and Mechanism of Partial Epithelial-Mesenchymal Transition in Kidney Fibrosis. Front Physiol. 2020;11:569322 Authors: Sheng L, Zhuang S Abstract Epithelial-mesenchymal transition (EMT) is described as the process in which injured renal tubular epithelial cells undergo a phenotype change, acquiring mesenchymal characteristics and morphing into fibroblasts. Initially, it was widely thought of as a critical mechanism...
Tue Oct 13, 2020 21:59
Study on mechanism of down-regulating ikca1 molecule affecting the increment of oral squamous cell carcinoma. Cell Mol Biol (Noisy-le-grand). 2020 Jul 31;66(5):59-65 Authors: Liu J, Guo Y Abstract This research aimed to explore the mechanism of mediating the down-regulation of the calcium-activated potassium channel (IKCa1) gene expression in human oral squamous cell carcinoma Tca-8113 cells, thereby affecting cell proliferation and apoptosis....
Tue Oct 13, 2020 21:59
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