IJERPH, Vol. 17, Pages 7469: Longitudinal Association between Sport Participation and Depressive Symptoms after a Two-Year Follow-Up in Mid-Adolescence International Journal of Environmental Research and Public Health doi: 10.3390/ijerph17207469 Authors: Gómez-Baya Calmeiro Gaspar Marques Loureiro Peralta Mendoza Gaspar de Matos Sport participation has been advocated as a strategy to improve adolescents’ mental health. However, how these variables...
Wed Oct 14, 2020 03:00
IJERPH, Vol. 17, Pages 7467: Predictors of Delirium in Octogenarian Patients Hospitalized for a Hip Fracture International Journal of Environmental Research and Public Health doi: 10.3390/ijerph17207467 Authors: María Plaza-Carmona Carmen Requena-Hernández Sonia Jiménez-Mola Introduction: Since delirium is a major complication that can arise after a patient with a hip fracture has been hospitalized, it is considered to be one of the most common geriatric conditions. Therefore,...
Wed Oct 14, 2020 03:00
IJERPH, Vol. 17, Pages 7462: A Safety Climate Framework for Improving Health and Safety in the Indonesian Construction Industry International Journal of Environmental Research and Public Health doi: 10.3390/ijerph17207462 Authors: Fatma Lestari Riza Yosia Sunindijo Martin Loosemore Yuni Kusminanti Baiduri Widanarko The Indonesian construction industry is the second largest in Asia and accounts for over 30% of all occupational injuries in the country. Despite the size of the...
Wed Oct 14, 2020 03:00
IJERPH, Vol. 17, Pages 7463: Hypertension Prevalence and Determinants among Black South African Adults in Semi-Urban and Rural Areas International Journal of Environmental Research and Public Health doi: 10.3390/ijerph17207463 Authors: Peter M. Mphekgwana Nancy Malema Kotsedi D. Monyeki Tebogo M. Mothiba Mpsanyana Makgahlela Nancy Kgatla Irene Makgato Tholene Sodi The burden of hypertension is reported to be on the rise in developing countries, such as South Africa,...
Wed Oct 14, 2020 03:00
IJERPH, Vol. 17, Pages 7461: Organizational Solutions to the Moral Risks of Policing International Journal of Environmental Research and Public Health doi: 10.3390/ijerph17207461 Authors: Daniel M. Blumberg Konstantinos Papazoglou Michael D. Schlosser In addition to the physical and emotional challenges faced by law enforcement professionals, the job confronts officers with numerous moral risks. The moral risks include moral distress, moral injury, ethical exhaustion, compassion...
Wed Oct 14, 2020 03:00
IJERPH, Vol. 17, Pages 7460: The Hospice as a Learning Environment: A Follow-Up Study with a Palliative Care Team International Journal of Environmental Research and Public Health doi: 10.3390/ijerph17207460 Authors: Ines Testoni Vito Fabio Sblano Lorenza Palazzo Sara Pompele Michael Alexander Wieser In Western society, the topic of death has been removed from everyday life and replaced with medical language. Such censorship does not reduce individuals’ fear of...
Wed Oct 14, 2020 03:00
IJMS, Vol. 21, Pages 7609: Pathophysiology and Treatment of Stroke: Present Status and Future Perspectives International Journal of Molecular Sciences doi: 10.3390/ijms21207609 Authors: Diji Kuriakose Zhicheng Xiao Stroke is the second leading cause of death and a major contributor to disability worldwide. The prevalence of stroke is highest in developing countries, with ischemic stroke being the most common type. Considerable progress has been made in our understanding of the pathophysiology...
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IJMS, Vol. 21, Pages 7602: A Common Kinetic Property of Mutations Linked to Episodic Ataxia Type 1 Studied in the Shaker Kv Channel International Journal of Molecular Sciences doi: 10.3390/ijms21207602 Authors: Juan Zhao Dimitri Petitjean Georges A. Haddad Zarah Batulan Rikard Blunck (1) Background: Episodic ataxia type 1 is caused by mutations in the KCNA1 gene encoding for the voltage-gated potassium channel Kv1.1. There have been many mutations in Kv1.1 linked to episodic...
Wed Oct 14, 2020 03:00
IJMS, Vol. 21, Pages 7608: Reduced Proteasome Activity and Enhanced Autophagy in Blood Cells of Psoriatic Patients International Journal of Molecular Sciences doi: 10.3390/ijms21207608 Authors: Piotr Karabowicz Adam Wroński Halina Ostrowska Georg Waeg Neven Zarkovic Elżbieta Skrzydlewska Psoriasis is a skin disease that is accompanied by oxidative stress resulting in modification of cell components, including proteins. Therefore, we investigated the relationship between...
Wed Oct 14, 2020 03:00
IJMS, Vol. 21, Pages 7606: Computational SNP Analysis and Molecular Simulation Revealed the Most Deleterious Missense Variants in the NBD1 Domain of Human ABCA1 Transporter International Journal of Molecular Sciences doi: 10.3390/ijms21207606 Authors: Raju Dash Md. Chayan Ali Md. Liton Rana Yeasmin Akter Munni Largess Barua Israt Jahan Mst. Fatema Haque Md. Abdul Hannan Il Soo Moon The ATP-binding cassette transporter A1 (ABCA1) is a membrane-bound exporter protein...
Wed Oct 14, 2020 03:00
IJMS, Vol. 21, Pages 7605: Mechanism of the Affinity-Enhancing Effect of Isatin on Human Ferrochelatase and Adrenodoxin Reductase Complex Formation: Implication for Protein Interactome Regulation International Journal of Molecular Sciences doi: 10.3390/ijms21207605 Authors: Pavel V. Ershov Alexander V. Veselovsky Yuri V. Mezentsev Evgeniy O. Yablokov Leonid A. Kaluzhskiy Anastasiya M. Tumilovich Anton A. Kavaleuski Andrei A. Gilep Taisiya V. Moskovkina Alexei E....
Wed Oct 14, 2020 03:00
IJMS, Vol. 21, Pages 7607: Role of Antimicrobial Peptides in Skin Barrier Repair in Individuals with Atopic Dermatitis International Journal of Molecular Sciences doi: 10.3390/ijms21207607 Authors: Hai Le Thanh Nguyen Juan Valentin Trujillo-Paez Yoshie Umehara Hainan Yue Ge Peng Chanisa Kiatsurayanon Panjit Chieosilapatham Pu Song Ko Okumura Hideoki Ogawa Shigaku Ikeda François Niyonsaba Atopic dermatitis (AD) is a common chronic inflammatory skin disease...
Wed Oct 14, 2020 03:00
IJMS, Vol. 21, Pages 7604: Oncolytic Virotherapy in Glioma Tumors International Journal of Molecular Sciences doi: 10.3390/ijms21207604 Authors: Sergio Rius-Rocabert Noemí García-Romero Antonia García Angel Ayuso-Sacido Estanislao Nistal-Villan Glioma tumors are one of the most devastating cancer types. Glioblastoma is the most advanced stage with the worst prognosis. Current therapies are still unable to provide an effective cure. Recent advances in oncolytic immunotherapy...
Wed Oct 14, 2020 03:00
IJMS, Vol. 21, Pages 7587: Irisin and Autophagy: First Update International Journal of Molecular Sciences doi: 10.3390/ijms21207587 Authors: Mirko Pesce Patrizia Ballerini Teresa Paolucci Iris Puca Mohammad Hosein Farzaei Antonia Patruno Aging and sedentary life style are considered independent risk factors for many disorders. Under these conditions, accumulation of dysfunctional and damaged cellular proteins and organelles occurs, resulting in a cellular degeneration...
Wed Oct 14, 2020 03:00
IJMS, Vol. 21, Pages 7603: Analysis of Spatio-Temporal Transcriptome Profiles of Soybean (Glycine max) Tissues during Early Seed Development International Journal of Molecular Sciences doi: 10.3390/ijms21207603 Authors: Shuo Sun Changyu Yi Jing Ma Shoudong Wang Marta Peirats-Llobet Mathew G. Lewsey James Whelan Huixia Shou Soybean (Glycine max) is an important crop providing oil and protein for both human and animal consumption. Knowing which biological processes...
Wed Oct 14, 2020 03:00
IJMS, Vol. 21, Pages 7601: Heterologous Expression of the Core Genes in the Complex Fusarubin Gene Cluster of Fusarium Solani International Journal of Molecular Sciences doi: 10.3390/ijms21207601 Authors: Tobias Bruun Pedersen Mikkel Rank Nielsen Sebastian Birkedal Kristensen Eva Mia Lang Spedtsberg Wafaa Yasmine Rikke Matthiesen Samba Evelyne Kabemba Kaniki Trine Sørensen Celine Petersen Jens Muff Teis Esben Sondergaard Kåre Lehmann Nielsen Reinhard Wimmer...
Wed Oct 14, 2020 03:00
IJMS, Vol. 21, Pages 7599: Temperature-Dependent Alternative Splicing of Precursor mRNAs and Its Biological Significance: A Review Focused on Post-Transcriptional Regulation of a Cold Shock Protein Gene in Hibernating Mammals International Journal of Molecular Sciences doi: 10.3390/ijms21207599 Authors: Takahiko Shiina Yasutake Shimizu Multiple mRNA isoforms are often generated during processing such as alternative splicing of precursor mRNAs (pre-mRNA), resulting in a diversity of...
Wed Oct 14, 2020 03:00
IJMS, Vol. 21, Pages 7583: Comparative Study of Silk-Based Magnetic Materials: Effect of Magnetic Particle Types on the Protein Structure and Biomaterial Properties International Journal of Molecular Sciences doi: 10.3390/ijms21207583 Authors: Ye Xue Samuel Lofland Xiao Hu This study investigates combining the good biocompatibility and flexibility of silk protein with three types of widely used magnetic nanoparticles to comparatively explore their structures, properties and potential...
Wed Oct 14, 2020 03:00
IJMS, Vol. 21, Pages 7600: Nanomedicine for Ischemic Stroke International Journal of Molecular Sciences doi: 10.3390/ijms21207600 Authors: Xinyue Dong Jin Gao Yujie Su Zhenjia Wang Stroke is a severe brain disease leading to disability and death. Ischemic stroke dominates in stroke cases, and there are no effective therapies in clinic, partly due to the challenges in delivering therapeutics to ischemic sites in the brain. This review is focused on the current knowledge of pathogenesis...
Wed Oct 14, 2020 03:00
IJMS, Vol. 21, Pages 7597: Influence of the TGF-β Superfamily on Osteoclasts/Osteoblasts Balance in Physiological and Pathological Bone Conditions International Journal of Molecular Sciences doi: 10.3390/ijms21207597 Authors: Jessica Jann Suzanne Gascon Sophie Roux Nathalie Faucheux The balance between bone forming cells (osteoblasts/osteocytes) and bone resorbing cells (osteoclasts) plays a crucial role in tissue homeostasis and bone repair. Several hormones, cytokines, and...
Wed Oct 14, 2020 03:00
IJMS, Vol. 21, Pages 7598: MGMT Promoter Methylation and IDH1 Mutations Do Not Affect [18F]FDOPA Uptake in Primary Brain Tumors International Journal of Molecular Sciences doi: 10.3390/ijms21207598 Authors: Andrea Cimini Agostino Chiaravalloti Maria Ricci Veronica Villani Gianluca Vanni Orazio Schillaci The aim of our study was to investigate the effects of methylation of O⁶-methylguanine-DNA methyltransferase promoter (MGMTp) and isocitrate dehydrogenase 1 (IDH 1) mutations...
Wed Oct 14, 2020 03:00
IJMS, Vol. 21, Pages 7596: Tissue-Specific Transcriptome Analysis Reveals Candidate Transcripts Associated with the Process of Programmed B Chromosome Elimination in Aegilops speltoides International Journal of Molecular Sciences doi: 10.3390/ijms21207596 Authors: Anastassia Boudichevskaia Alevtina Ruban Johannes Thiel Anne Fiebig Andreas Houben Some eukaryotes exhibit dramatic genome size differences between cells of different organs, resulting from programmed elimination...
Wed Oct 14, 2020 03:00
IJMS, Vol. 21, Pages 7586: Raloxifene as Treatment for Various Types of Brain Injuries and Neurodegenerative Diseases: A Good Start International Journal of Molecular Sciences doi: 10.3390/ijms21207586 Authors: Leo Veenman Recent studies have shown that the selective estrogen receptor modulator (SERM) raloxifene had pronounced protective effects against progressing brain damage after traumatic brain injury (TBI) in mice. These studies, indicating beneficial effects of raloxifene for...
Wed Oct 14, 2020 03:00
IJMS, Vol. 21, Pages 7595: Targeting Mechanotransduction in Osteosarcoma: A Comparative Oncology Perspective International Journal of Molecular Sciences doi: 10.3390/ijms21207595 Authors: Anita K. Luu Alicia M. Viloria-Petit Mechanotransduction is the process in which cells can convert extracellular mechanical stimuli into biochemical changes within a cell. While this a normal process for physiological development and function in many organ systems, tumour cells can exploit this process...
Wed Oct 14, 2020 03:00
IJMS, Vol. 21, Pages 7594: Membrane Curvature, Trans-Membrane Area Asymmetry, Budding, Fission and Organelle Geometry International Journal of Molecular Sciences doi: 10.3390/ijms21207594 Authors: Alexander A. Mironov Anna Mironov Jure Derganc Galina V. Beznoussenko In biology, the modern scientific fashion is to mostly study proteins. Much less attention is paid to lipids. However, lipids themselves are extremely important for the formation and functioning of cellular membrane...
Wed Oct 14, 2020 03:00
IJMS, Vol. 21, Pages 7592: Multiple Endocrine Neoplasia Type 1: The Potential Role of microRNAs in the Management of the Syndrome International Journal of Molecular Sciences doi: 10.3390/ijms21207592 Authors: Simone Donati Simone Ciuffi Francesca Marini Gaia Palmini Francesca Miglietta Cinzia Aurilia Maria Luisa Brandi Multiple endocrine neoplasia type 1 (MEN1) is a rare inherited tumor syndrome, characterized by the development of multiple neuroendocrine tumors (NETs)...
Wed Oct 14, 2020 03:00
IJMS, Vol. 21, Pages 7591: Regulation of Platelet Production and Life Span: Role of Bcl-xL and Potential Implications for Human Platelet Diseases International Journal of Molecular Sciences doi: 10.3390/ijms21207591 Authors: Emma C. Josefsson William Vainchenker Chloe James Blood platelets have important roles in haemostasis, where they quickly stop bleeding in response to vascular damage. They have also recognised functions in thrombosis, immunity, antimicrobal defense, cancer...
Wed Oct 14, 2020 03:00
IJMS, Vol. 21, Pages 7593: Unveiling the Actual Functions of Awns in Grasses: From Yield Potential to Quality Traits International Journal of Molecular Sciences doi: 10.3390/ijms21207593 Authors: Fabrice Ntakirutimana Wengang Xie Awns, which are either bristles or hair-like outgrowths of lemmas in the florets, are one of the typical morphological characteristics of grass species. These stiff structures contribute to grain dispersal and burial and fend off animal predators. However,...
Wed Oct 14, 2020 03:00
IJMS, Vol. 21, Pages 7589: Bovine Oviduct Epithelial Cell-Derived Culture Media and Exosomes Improve Mitochondrial Health by Restoring Metabolic Flux during Pre-Implantation Development International Journal of Molecular Sciences doi: 10.3390/ijms21207589 Authors: Tabinda Sidrat Abdul Aziz Khan Myeon-Don Joo Yiran Wei Kyeong-Lim Lee Lianguang Xu Il-Keun Kong Oviduct flushing is enriched by a wide variety of nutrients that guide the 3–4 days journey of pre-implantation...
Wed Oct 14, 2020 03:00
IJMS, Vol. 21, Pages 7588: Atorvastatin Augments Gemcitabine-Mediated Anti-Cancer Effects by Inhibiting Yes-Associated Protein in Human Cholangiocarcinoma Cells International Journal of Molecular Sciences doi: 10.3390/ijms21207588 Authors: Koh Kitagawa Kei Moriya Kosuke Kaji Soichiro Saikawa Shinya Sato Norihisa Nishimura Tadashi Namisaki Takemi Akahane Akira Mitoro Hitoshi Yoshiji Cholangiocarcinoma (CCA) is associated with high mortality rates because of...
Wed Oct 14, 2020 03:00
IJMS, Vol. 21, Pages 7590: Looking for Targets to Restore the Contractile Function in Congenital Myopathy Caused by Gln147Pro Tropomyosin International Journal of Molecular Sciences doi: 10.3390/ijms21207590 Authors: Olga E. Karpicheva Armen O. Simonyan Nikita A. Rysev Charles S. Redwood Yurii S. Borovikov We have used the technique of polarized microfluorimetry to obtain new insight into the pathogenesis of skeletal muscle disease caused by the Gln147Pro substitution in...
Wed Oct 14, 2020 03:00
IJMS, Vol. 21, Pages 7585: Integrative Analysis of Regulatory Module Reveals Associations of Microgravity with Dysfunctions of Multi-body Systems and Tumorigenesis International Journal of Molecular Sciences doi: 10.3390/ijms21207585 Authors: Mengqin Yuan Haizhou Liu Shunheng Zhou Xu Zhou Yu-e Huang Fei Hou Wei Jiang Previous studies have demonstrated that microgravity could lead to health risks. The investigation of the molecular mechanisms from the aspect of systems...
Wed Oct 14, 2020 03:00
IJMS, Vol. 21, Pages 7584: Intestinal Explant Cultures from Gilthead Seabream (Sparus aurata, L.) Allowed the Determination of Mucosal Sensitivity to Bacterial Pathogens and the Impact of a Plant Protein Diet International Journal of Molecular Sciences doi: 10.3390/ijms21207584 Authors: David Sánchez Peñaranda Christine Bäuerl Ana Tomás-Vidal Miguel Jover-Cerdá Guillem Estruch Gaspar Pérez Martínez Silvia Martínez Llorens The interaction between diet and intestinal...
Wed Oct 14, 2020 03:00
IJMS, Vol. 21, Pages 7582: Moderate Aerobic Exercise Training Prevents the Augmented Hepatic Glucocorticoid Response Induced by High-Fat Diet in Mice International Journal of Molecular Sciences doi: 10.3390/ijms21207582 Authors: Jonatan Dassonvalle Francisco Díaz-Castro Camila Donoso-Barraza Carlos Sepúlveda Francisco Pino-de la Fuente Pamela Pino Alejandra Espinosa Mario Chiong Miguel Llanos Rodrigo Troncoso Glucocorticoids (GCs) are critical regulators of...
Wed Oct 14, 2020 03:00
IJMS, Vol. 21, Pages 7580: Intimate Relations—Mitochondria and Ageing International Journal of Molecular Sciences doi: 10.3390/ijms21207580 Authors: Webb Sideris Mitochondrial dysfunction is associated with ageing, but the detailed causal relationship between the two is still unclear. We review the major phenomenological manifestations of mitochondrial age-related dysfunction including biochemical, regulatory and energetic features. We conclude that the complexity of these processes...
Wed Oct 14, 2020 03:00
IJMS, Vol. 21, Pages 7575: Microbes as Medicines: Harnessing the Power of Bacteria in Advancing Cancer Treatment International Journal of Molecular Sciences doi: 10.3390/ijms21207575 Authors: Shruti S. Sawant Suyash M. Patil Vivek Gupta Nitesh K. Kunda Conventional anti-cancer therapy involves the use of chemical chemotherapeutics and radiation and are often non-specific in action. The development of drug resistance and the inability of the drug to penetrate the tumor cells...
Wed Oct 14, 2020 03:00
IJMS, Vol. 21, Pages 7579: 12-Deoxyphorbol Esters Induce Growth Arrest and Apoptosis in Human Lung Cancer A549 Cells via Activation of PKC-δ/PKD/ERK Signaling Pathway International Journal of Molecular Sciences doi: 10.3390/ijms21207579 Authors: Ju-Ying Tsai Dóra Rédei Judit Hohmann Chin-Chung Wu Prostratin, a non-tumor promoting 12-deoxyphorbol ester, has been reported as a protein kinase C (PKC) activator and is shown to have anti-proliferative activity in certain cancer cell...
Wed Oct 14, 2020 03:00
IJMS, Vol. 21, Pages 7581: Serotonin Transporter and Plasma Membrane Monoamine Transporter Are Necessary for the Antidepressant-Like Effects of Ketamine in Mice International Journal of Molecular Sciences doi: 10.3390/ijms21207581 Authors: Melodi A. Bowman Melissa Vitela Kyra M. Clarke Wouter Koek Lynette C. Daws Major depressive disorder is typically treated with selective serotonin reuptake inhibitors (SSRIs), however, SSRIs take approximately six weeks to produce therapeutic...
Wed Oct 14, 2020 03:00
IJMS, Vol. 21, Pages 7577: Current Progress in Cross-Linked Peptide Self-Assemblies International Journal of Molecular Sciences doi: 10.3390/ijms21207577 Authors: Noriyuki Uchida Takahiro Muraoka Peptide-based fibrous supramolecular assemblies represent an emerging class of biomaterials that can realize various bioactivities and structures. Recently, a variety of peptide fibers with attractive functions have been designed together with the discovery of many peptide-based self-assembly...
Wed Oct 14, 2020 03:00
IJMS, Vol. 21, Pages 7576: Mechanism and Function of the Catch State in Molluscan Smooth Muscle: A Historical Perspective International Journal of Molecular Sciences doi: 10.3390/ijms21207576 Authors: Haruo Sugi Tetsuo Ohno Masamichi Moriya Molluscan smooth muscles exhibit the catch state, in which both tension and resistance to stretch are maintained with very low rates of energy consumption. The catch state is studied mainly on the anterior byssus retractor muscle (ABRM) of a...
Wed Oct 14, 2020 03:00
IJMS, Vol. 21, Pages 7572: Integrated Analysis of the Transcriptome and Metabolome of Cecropia obtusifolia: A Plant with High Chlorogenic Acid Content Traditionally Used to Treat Diabetes Mellitus International Journal of Molecular Sciences doi: 10.3390/ijms21207572 Authors: Jorge David Cadena-Zamudio Pilar Nicasio-Torres Juan Luis Monribot-Villanueva José Antonio Guerrero-Analco Enrique Ibarra-Laclette This investigation cultured Cecropia obtusifolia cells in suspension...
Wed Oct 14, 2020 03:00
IJMS, Vol. 21, Pages 7578: Profiling of Tryptophan Metabolic Pathways in the Rat Fetoplacental Unit During Gestation International Journal of Molecular Sciences doi: 10.3390/ijms21207578 Authors: Cilia Abad Rona Karahoda Petr Kastner Ramon Portillo Hana Horackova Radim Kucera Petr Nachtigal Frantisek Staud Placental homeostasis of tryptophan is essential for fetal development and programming. The two main metabolic pathways (serotonin and kynurenine) produce bioactive...
Wed Oct 14, 2020 03:00
IJMS, Vol. 21, Pages 7574: In Vivo Modulation of Angiogenesis and Immune Response on a Collagen Matrix via Extracorporeal Shockwaves International Journal of Molecular Sciences doi: 10.3390/ijms21207574 Authors: Diana Heimes Nadine Wiesmann Jonas Eckrich Juergen Brieger Stefan Mattyasovszky Peter Proff Manuel Weber James Deschner Bilal Al-Nawas Peer W. Kämmerer The effective management of tissue integration and immunological responses to transplants decisively...
Wed Oct 14, 2020 03:00
IJMS, Vol. 21, Pages 7573: The Heavy Chain 4F2hc Modulates the Substrate Affinity and Specificity of the Light Chains LAT1 and LAT2 International Journal of Molecular Sciences doi: 10.3390/ijms21207573 Authors: Satish Kantipudi Jean-Marc Jeckelmann Zöhre Ucurum Patrick D. Bosshart Dimitrios Fotiadis The human L-type amino acid transporters LAT1 and LAT2 mediate the transport of amino acids and amino acid derivatives across plasma membranes in a sodium-independent, obligatory...
Wed Oct 14, 2020 03:00
IJMS, Vol. 21, Pages 7571: From 1957 to Nowadays: A Brief History of Epigenetics International Journal of Molecular Sciences doi: 10.3390/ijms21207571 Authors: Paul Peixoto Pierre-François Cartron Aurélien A. Serandour Eric Hervouet Due to the spectacular number of studies focusing on epigenetics in the last few decades, and particularly for the last few years, the availability of a chronology of epigenetics appears essential. Indeed, our review places epigenetic events and...
Wed Oct 14, 2020 03:00
IJMS, Vol. 21, Pages 7570: The Role of the RANKL/RANK Axis in the Prevention and Treatment of Breast Cancer with Immune Checkpoint Inhibitors and Anti-RANKL International Journal of Molecular Sciences doi: 10.3390/ijms21207570 Authors: Aristofania Simatou Panagiotis Sarantis Evangelos Koustas Athanasios G. Papavassiliou Michalis V. Karamouzis The receptor activator of nuclear factor-κB (RANK) and the RANK ligand (RANKL) were reported in the regulation of osteoclast...
Wed Oct 14, 2020 03:00
IJNS, Vol. 6, Pages 79: Validation and Implementation of a Highly Sensitive and Efficient Newborn Screening Assay for Mucopolysaccharidosis Type II International Journal of Neonatal Screening doi: 10.3390/ijns6040079 Authors: Heather Bilyeu Jon Washburn Lacey Vermette Tracy Klug Mucopolysaccharidosis Type II (MPS II), also known as Hunter syndrome, is a lysosomal storage disorder (LSD) caused by a deficiency of the lysosomal enzyme iduronate-2-sulfatase (IDS). MPS II satisfies...
Wed Oct 14, 2020 03:00
JCM, Vol. 9, Pages 3305: Estimating Minimal Clinically Important Differences for Knee Range of Motion after Stroke Journal of Clinical Medicine doi: 10.3390/jcm9103305 Authors: Agnieszka Guzik Mariusz Drużbicki Andżelina Wolan-Nieroda Andrea Turolla Pawel Kiper The importance of knee sagittal kinematic parameters, as a predictor of walking performance in post-stroke gait has been emphasised by numerous researchers. However, no studies so far were designed to determine the...
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JCM, Vol. 9, Pages 3294: Using the Thickness Map from Macular Ganglion Cell Analysis to Differentiate Retinal Vein Occlusion from Glaucoma Journal of Clinical Medicine doi: 10.3390/jcm9103294 Authors: Nam Ho Lee Kee Sup Park Han Min Lee Jung Yeul Kim Chang-sik Kim Kyoung Nam Kim Purpose: We hypothesized that the thickness map from macular ganglion cell analysis (GCA) acquired from spectral-domain optical coherence tomography can be used to differentiate retinal vein occlusion...
Wed Oct 14, 2020 03:00
JCM, Vol. 9, Pages 3303: Deep Learning-Based Classification of Inherited Retinal Diseases Using Fundus Autofluorescence Journal of Clinical Medicine doi: 10.3390/jcm9103303 Authors: Alexandra Miere Thomas Le Meur Karen Bitton Carlotta Pallone Oudy Semoun Vittorio Capuano Donato Colantuono Kawther Taibouni Yasmina Chenoune Polina Astroz Sylvain Berlemont Eric Petit Eric Souied Background. In recent years, deep learning has been increasingly applied...
Wed Oct 14, 2020 03:00
JCM, Vol. 9, Pages 3304: Self-Reported Practices in Opioid Management of Chronic Noncancer Pain: An Updated Survey of Canadian Family Physicians Journal of Clinical Medicine doi: 10.3390/jcm9103304 Authors: Andrea D. Furlan Santana Diaz Angela Carol Peter MacDougall Michael Allen Chronic pain affects one in five Canadians, and opioids continue to be prescribed to 12.3% of the Canadian population. A survey of family physicians was conducted in 2010 as a baseline prior to the...
Wed Oct 14, 2020 03:00
JCM, Vol. 9, Pages 3301: Wedge-Shaped Implants for Minimally Invasive Treatment of Narrow Ridges: A Multicenter Prospective Cohort Study Journal of Clinical Medicine doi: 10.3390/jcm9103301 Authors: Vercellotti Troiano Oreglia Lombardi Gregorig Morella Rapani Stacchi The present study aims to investigate clinical and patient-centered outcomes after the implant-supported rehabilitation of narrow ridges using a novel wedge-shaped implant. Forty-four patients...
Wed Oct 14, 2020 03:00
JCM, Vol. 9, Pages 3302: Interval Cancer Rate and Diagnostic Performance of Fecal Immunochemical Test According to Family History of Colorectal Cancer Journal of Clinical Medicine doi: 10.3390/jcm9103302 Authors: Jung Lee Lee Moon Background: The potential role of the fecal immunochemical test (FIT) in individuals with a family history of colorectal cancer (CRC) remains unclear. We assessed interval cancer rate (ICR) after the FIT and FIT diagnostic performance according...
Wed Oct 14, 2020 03:00
JCM, Vol. 9, Pages 3298: Pre-Liver Transplant ROTEM™ Clot Lysis Index Is Associated with 30-Day Mortality, But Is Not a Measure for Fibrinolysis Journal of Clinical Medicine doi: 10.3390/jcm9103298 Authors: Matthias Hartmann Bogdan Craciun Andreas Paul Thorsten Brenner Fuat H. Saner Complex alterations of the coagulation system in end stage liver disease lead to an increased risk of bleeding and mortality. In the present study, we investigated; 1. the association of pre-liver...
Wed Oct 14, 2020 03:00
JCM, Vol. 9, Pages 3295: Percutaneous Endoscopic Gastrostomy and Nutritional Interventions by the Pediatric Nutritional Support Team Improve the Nutritional Status of Neurologically Impaired Children Journal of Clinical Medicine doi: 10.3390/jcm9103295 Authors: Chae-ri Suh Wonkyung Kim Baik-Lin Eun Jung Ok Shim Aim: To evaluate the long-term effects of nutritional improvement following percutaneous endoscopic gastrostomy (PEG) tube feeding stratified by previous feeding method...
Wed Oct 14, 2020 03:00
JCM, Vol. 9, Pages 3299: Transcriptomic Profile of Genes Encoding Proteins Involved in Pathogenesis of Sjögren’s Syndrome Related Xerostomia—Molecular and Clinical Trial Journal of Clinical Medicine doi: 10.3390/jcm9103299 Authors: Katarzyna Błochowiak Piotr Celichowski Bartosz Kempisty Katarzyna Iwanik Michał Nowicki Sjögren’s syndrome (SS) is characterized by xerostomia. We aimed to investigate and compare gene expressions in the labial salivary glands...
Wed Oct 14, 2020 03:00
JCM, Vol. 9, Pages 3300: Effectiveness of Dry Needling for Myofascial Trigger Points Associated with Neck Pain Symptoms: An Updated Systematic Review and Meta-Analysis Journal of Clinical Medicine doi: 10.3390/jcm9103300 Authors: Navarro-Santana Sanchez-Infante Fernández-de-las-Peñas Cleland Martín-Casas Plaza-Manzano Our aim was to evaluate the effect of dry needling alone as compared to sham needling, no intervention, or other physical interventions applied over...
Wed Oct 14, 2020 03:00
JCM, Vol. 9, Pages 3296: Is There a Link between Bisphenol A (BPA), a Key Endocrine Disruptor, and the Risk for SARS-CoV-2 Infection and Severe COVID-19? Journal of Clinical Medicine doi: 10.3390/jcm9103296 Authors: Aeman Zahra Cristina Sisu Elisabete Silva Sophie-Christine De Aguiar Greca Harpal S. Randeva Kamaljit Chatha Ioannis Kyrou Emmanouil Karteris Infection by the severe acute respiratory syndrome (SARS) coronavirus-2 (SARS-CoV-2) is the causative agent of...
Wed Oct 14, 2020 03:00
JCM, Vol. 9, Pages 3297: Insights into the Procoagulant Profile of Patients with Systemic Lupus Erythematosus without Antiphospholipid Antibodies Journal of Clinical Medicine doi: 10.3390/jcm9103297 Authors: Elena Monzón Manzano Ihosvany Fernández-Bello Raúl Justo Sanz Ángel Robles Marhuenda Francisco Javier López-Longo Paula Acuña María Teresa Álvarez Román Víctor Jiménez Yuste Nora V. Butta We aimed to identify the key players in the prothrombotic profile of...
Wed Oct 14, 2020 03:00
JCM, Vol. 9, Pages 3293: Presentation, Treatment Response and Short-Term Outcomes in Paediatric Multisystem Inflammatory Syndrome Temporally Associated with SARS-CoV-2 (PIMS-TS) Journal of Clinical Medicine doi: 10.3390/jcm9103293 Authors: Felsenstein Willis Lythgoe McCann Cleary Mahmood Porter Jones McDonagh Chieng Varnier Hughes Boullier Ryan Awogbemi Soda Duong Pain Riley Hedrich The novel Severe Acute Respiratory...
Wed Oct 14, 2020 03:00
JCM, Vol. 9, Pages 3292: The Role of Ribonuclease 1 and Ribonuclease Inhibitor 1 in Acute Kidney Injury after Open and Endovascular Thoracoabdominal Aortic Aneurysm Repair Journal of Clinical Medicine doi: 10.3390/jcm9103292 Authors: Elisabeth Zechendorf Alexander Gombert Tanja Bülow Nadine Frank Christian Beckers Arne Peine Drosos Kotelis Michael J. Jacobs Gernot Marx Lukas Martin Acute kidney injury (AKI) is one of the most common post-operative complications...
Wed Oct 14, 2020 03:00
JFMK, Vol. 5, Pages 74: The “Journal of Functional Morphology and Kinesiology” Journal Club Series: Highlights on Recent Papers in Corrective Exercise Journal of Functional Morphology and Kinesiology doi: 10.3390/jfmk5040074 Authors: Antonino Bianco Silvio Lorenzetti Jan Seiler Heiliane de Brito Fontana Walter Herzog Gessica Aline Silvano Heron Baptista de Oliveira Medeiros Giuseppe Musumeci We are glad to introduce the Journal Club of Volume Five, fourth Issue....
Wed Oct 14, 2020 03:00
JPM, Vol. 10, Pages 170: Genetic Ablation of MiR-22 Fosters Diet-Induced Obesity and NAFLD Development Journal of Personalized Medicine doi: 10.3390/jpm10040170 Authors: Monika Gjorgjieva Cyril Sobolewski Anne-Sophie Ay Daniel Abegg Marta Correia de Sousa Dorothea Portius Flavien Berthou Margot Fournier Christine Maeder Pia Rantakari Fu-Ping Zhang Matti Poutanen Didier Picard Xavier Montet Serge Nef Alexander Adibekian Michelangelo Foti miR-22...
Wed Oct 14, 2020 03:00
JPM, Vol. 10, Pages 169: GWAS of Post-Orthodontic Aggressive External Apical Root Resorption Identified Multiple Putative Loci at X-Y Chromosomes Journal of Personalized Medicine doi: 10.3390/jpm10040169 Authors: Paula Iber-Díaz Raquel Senen-Carramolino Alejandro Iglesias-Linares Pablo Fernández-Navarro Carlos Flores-Mir Rosa M Yañez-Vico Personalized dental medicine requires from precise and customized genomic diagnostic. To conduct an association analysis over multiple...
Wed Oct 14, 2020 03:00
Life, Vol. 10, Pages 241: Non-Criteria Antiphospholipid Antibodies: Risk Factors for Endothelial Dysfunction in Women with Pre-Eclampsia Life doi: 10.3390/life10100241 Authors: Belmar Vega Fernández Fresnedo Irure Ventura Orallo Toural Vicario San Millán Rodrigo Hoyos The association between unconventional antiphospholipid antibodies and pre-eclampsia in patients without thrombotic manifestations and its relationship with endothelial dysfunction after delivery...
Wed Oct 14, 2020 03:00
Life, Vol. 10, Pages 240: Electroacupuncture on the Scalp over the Motor Cortex Ameliorates Behavioral Deficits Following Neonatal Hypoxia-Ischemia in Rats via the Activation of Neural Stem Cells Life doi: 10.3390/life10100240 Authors: Da Hee Jung Malk Eun Pak Hong Ju Lee Sung Min Ahn Young Ju Yun Yong-Il Shin Hwa Kyoung Shin Seo-Yeon Lee Byung Tae Choi Electroacupuncture (EA) therapy via alternating current stimulation on the scalp over the motor cortex is used...
Wed Oct 14, 2020 03:00
Life, Vol. 10, Pages 239: Markers of Endothelial Injury and Dysfunction in Early- and Late-Onset Preeclampsia Life doi: 10.3390/life10100239 Authors: Jakub Kornacki Przemysław Wirstlein Ewa Wender-Ozegowska With regard to differences in the clinical symptoms of preeclampsia (PE), the degree of endothelial dysfunction may differ between early and late-onset preeclampsia (EOP and LOP). The authors of this study examined it by assessing the endothelial injury level in women with EOP...
Wed Oct 14, 2020 03:00
Medicina, Vol. 56, Pages 539: Chemically Activated Cooling Vest’s Effect on Cooling Rate Following Exercise-Induced Hyperthermia: A Randomized Counter-Balanced Crossover Study Medicina doi: 10.3390/medicina56100539 Authors: Yuri Hosokawa Luke N. Belval William M. Adams Lesley W. Vandermark Douglas J. Casa Background and objectives: Exertional heat stroke (EHS) is a potentially lethal, hyperthermic condition that warrants immediate cooling to optimize the patient outcome....
Wed Oct 14, 2020 03:00
Medicina, Vol. 56, Pages 540: The Impact of Time-Restricted Diet on Sleep and Metabolism in Obese Volunteers Medicina doi: 10.3390/medicina56100540 Authors: Hyeyun Kim Bong Jin Jang A Ram Jung Jayoung Kim Hyo jin Ju Yeong In Kim Background and objectives: A time-restricted diet is one of the various ways to improve metabolic condition and weight control. However, until now, there have been few pieces of evidence and research to verify the methods and effectiveness of time-restricted...
Wed Oct 14, 2020 03:00
Medicina, Vol. 56, Pages 541: Gastric Calcifying Fibrous Tumor: An Easy Misdiagnosis as Gastrointestinal Stromal Tumor–A Systemic Review Medicina doi: 10.3390/medicina56100541 Authors: Meng-Ko Tsai Hung-Yi Chen Ming-Lung Chuang Chun-Wen Chen Gwo-Ping Jong Background and Objectives: Calcifying fibrous tumor (CFT) in the stomach is extremely rare and is easily misdiagnosed as a gastrointestinal stromal tumor (GIST). This study aims to determine the best method to differentiate...
Wed Oct 14, 2020 03:00
Medicina, Vol. 56, Pages 538: The Influence of Warm-Up on Body Temperature and Strength Performance in Brazilian National-Level Paralympic Powerlifting Athletes Medicina doi: 10.3390/medicina56100538 Authors: Marcelo de Aquino Resende Roberta Barreto Vasconcelos Resende Gracielle Costa Reis Layanne de Oliveira Barros Madson Rodrigo Silva Bezerra Dihogo Gama de Matos Anderson Carlos Marçal Paulo Francisco de Almeida-Neto Breno Guilherme de Araújo Tinoco Cabral Henrique...
Wed Oct 14, 2020 03:00
Membranes, Vol. 10, Pages 284: Forward Osmosis as Concentration Process: Review of Opportunities and Challenges Membranes doi: 10.3390/membranes10100284 Authors: Gaetan Blandin Federico Ferrari Geoffroy Lesage Pierre Le-Clech Marc Héran Xavier Martinez-Lladó In the past few years, osmotic membrane systems, such as forward osmosis (FO), have gained popularity as “soft” concentration processes. FO has unique properties by combining high rejection rate...
Wed Oct 14, 2020 03:00
Membranes, Vol. 10, Pages 283: Analysis of Dynamics Targeting CNT-Based Drug Delivery through Lung Cancer Cells: Design, Simulation, and Computational Approach Membranes doi: 10.3390/membranes10100283 Authors: Nafiseh Sohrabi Afshar Alihosseini Vahid Pirouzfar Maysam Zamani Pedram Nowadays, carbon nano (CN) structures and specifically carbon nanotubes (CNTs), because of the nanotube’s nanoscale shape, are widely used in carrier and separation applications. The conjugation...
Wed Oct 14, 2020 03:00
Metabolites, Vol. 10, Pages 413: Temperate Propolis Has Anti-Inflammatory Effects and Is a Potent Inhibitor of Nitric Oxide Formation in Macrophages Metabolites doi: 10.3390/metabo10100413 Authors: Samyah Alanazi Naif Alenzi James Fearnley William Harnett David G. Watson Previous research has shown that propolis has immunomodulatory activity. Extracts from two UK propolis samples were assessed for their anti-inflammatory activities by investigating their ability to alter...
Wed Oct 14, 2020 03:00
Metabolites, Vol. 10, Pages 412: Carbonic Anhydrase Inhibitors Targeting Metabolism and Tumor Microenvironment Metabolites doi: 10.3390/metabo10100412 Authors: Andrea Angeli Fabrizio Carta Alessio Nocentini Jean-Yves Winum Raivis Zalubovskis Atilla Akdemir Valentina Onnis Wagdy M. Eldehna Clemente Capasso Giuseppina De Simone Simona Maria Monti Simone Carradori William A. Donald Shoukat Dedhar Claudiu T. Supuran The tumor microenvironment is...
Wed Oct 14, 2020 03:00
Metabolites, Vol. 10, Pages 410: Adipocytokines and Metabolic Syndrome in Patients with Schizophrenia Metabolites doi: 10.3390/metabo10100410 Authors: Irina A. Mednova Anastasiia S. Boiko Elena G. Kornetova Daria A. Parshukova Arkadiy V. Semke Nikolay A. Bokhan Anton J. M. Loonen Svetlana A. Ivanova The adipokines leptin, adiponectin, tumor necrosis factor-alpha (TNF-α), and interleukin 6 (IL-6) might be associated with metabolic syndrome (MetS) in patients...
Wed Oct 14, 2020 03:00
Metabolites, Vol. 10, Pages 411: Role of the Mitochondrial Pyruvate Carrier in the Occurrence of Metabolic Inflexibility in Drosophila melanogaster Exposed to Dietary Sucrose Metabolites doi: 10.3390/metabo10100411 Authors: Chloé J. Simard Mohamed Touaibia Eric Pierre Allain Etienne Hebert-Chatelain Nicolas Pichaud Excess dietary carbohydrates are linked to dysregulation of metabolic pathways converging to mitochondria and metabolic inflexibility. Here, we determined the...
Wed Oct 14, 2020 03:00
MPs, Vol. 3, Pages 69: An Efficient Method for Isolation of Plasmid DNA for Transfection of Mammalian Cell Cultures Methods and Protocols doi: 10.3390/mps3040069 Authors: Daniel V. Kachkin Julia I. Khorolskaya Julia S. Ivanova Aleksandr A. Rubel In this article, we present several protocols that describe the steps from cloning and obtaining a large amount of pure plasmid DNA to generation of lentiviruses based on these constructs. The protocols have been worked out on human...
Wed Oct 14, 2020 03:00
Microorganisms, Vol. 8, Pages 1584: Prevotella in Pigs: The Positive and Negative Associations with Production and Health Microorganisms doi: 10.3390/microorganisms8101584 Authors: Samat Amat Hannah Lantz Peris M. Munyaka Benjamin P. Willing A diverse and dynamic microbial community (known as microbiota) resides within the pig gastrointestinal tract (GIT). The microbiota contributes to host health and performance by mediating nutrient metabolism, stimulating the immune system,...
Wed Oct 14, 2020 03:00
Microorganisms, Vol. 8, Pages 1585: Culturable Bacterial Community on Leaves of Assam Tea (Camellia sinensis var. assamica) in Thailand and Human Probiotic Potential of Isolated Bacillus spp Microorganisms doi: 10.3390/microorganisms8101585 Authors: Patthanasak Rungsirivanich Witsanu Supandee Wirapong Futui Vipanee Chumsai-Na-Ayudhya Chaowarin Yodsombat Narumol Thongwai Assam tea plants (Camellia sinensis var. assamica) or Miang are found in plantations and forests of...
Wed Oct 14, 2020 03:00
Microorganisms, Vol. 8, Pages 1582: Bioaminergic Responses in an In Vitro System Studying Human Gut Microbiota–Kiwifruit Interactions Microorganisms doi: 10.3390/microorganisms8101582 Authors: Shanthi G. Parkar Carel M. H. Jobsis Tania M. Trower Janine M. Cooney Duncan I. Hedderley Kerry L. Bentley-Hewitt Whole kiwifruit (‘Hayward’ and ‘Zesy002’) were examined for their bioaminergic potential after being subjected to in vitro gastrointestinal...
Wed Oct 14, 2020 03:00
Microorganisms, Vol. 8, Pages 1580: Biofilms in Diabetic Foot Ulcers: Significance and Clinical Relevance Microorganisms doi: 10.3390/microorganisms8101580 Authors: Cassandra Pouget Catherine Dunyach-Remy Alix Pantel Sophie Schuldiner Albert Sotto Jean-Philippe Lavigne Foot infections are the main disabling complication in patients with diabetes mellitus. These infections can lead to lower-limb amputation, increasing mortality and decreasing the quality of life. Biofilm...
Wed Oct 14, 2020 03:00
Microorganisms, Vol. 8, Pages 1581: Investigation of Age-Related Changes in the Skin Microbiota of Korean Women Microorganisms doi: 10.3390/microorganisms8101581 Authors: Minseok Kim Tansol Park Jung Im Yun Hye Won Lim Na Rae Han Seung Tae Lee The microbiota of human skin is influenced by host and environmental factors. To determine if chronological age influences the composition of the skin microbiota on the forehead and hands, 73 Korean women were sorted into one of...
Wed Oct 14, 2020 03:00
Microorganisms, Vol. 8, Pages 1583: Evaluation of Yeast Strains for Pomegranate Alcoholic Beverage Production: Effect on Physicochemical Characteristics, Antioxidant Activity, and Aroma Compounds Microorganisms doi: 10.3390/microorganisms8101583 Authors: Evangelos Kokkinomagoulos Anastasios Nikolaou Yiannis Kourkoutas Panagiotis Kandylis In the present study, three commercial yeasts (for wine, beer, and cider) were evaluated for the production of pomegranate alcoholic beverage...
Wed Oct 14, 2020 03:00
Microorganisms, Vol. 8, Pages 1578: Inter- and Intra-Species Diversity of Lactic Acid Bacteria in Apis mellifera ligustica Colonies Microorganisms doi: 10.3390/microorganisms8101578 Authors: Massimo Iorizzo Gianfranco Pannella Silvia Jane Lombardi Sonia Ganassi Bruno Testa Mariantonietta Succi Elena Sorrentino Sonia Petrarca Antonio De Cristofaro Raffaele Coppola Patrizio Tremonte Lactic acid bacteria could positively affect the health of honey bees, including...
Wed Oct 14, 2020 03:00
Microorganisms, Vol. 8, Pages 1579: The Core and Distinction of the Gut Microbiota in Chinese Populations across Geography and Ethnicity Microorganisms doi: 10.3390/microorganisms8101579 Authors: Deng Lin Ran Wang Junjie Luo Fazheng Ren Zhenglong Gu Yiqiang Zhao Liang Zhao The diversity of the human gut microbiota constitutes a fundamental health indicator of different populations. The relative importance of geographical location and ethnicity on the gut microbiota,...
Wed Oct 14, 2020 03:00
Molecules, Vol. 25, Pages 4705: Expansion of Intrinsically Disordered Proteins Increases the Range of Stability of Liquid–Liquid Phase Separation Molecules doi: 10.3390/molecules25204705 Authors: Adiran Garaizar Ignacio Sanchez-Burgos Rosana Collepardo-Guevara Jorge R. Espinosa Proteins containing intrinsically disordered regions (IDRs) are ubiquitous within biomolecular condensates, which are liquid-like compartments within cells formed through liquid–liquid phase...
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Molecules, Vol. 25, Pages 4696: A Machine Learning Approach in Analyzing Bioaccumulation of Heavy Metals in Turbot Tissues Molecules doi: 10.3390/molecules25204696 Authors: Ștefan-Mihai Petrea Mioara Costache Dragoș Cristea Ștefan-Adrian Strungaru Ira-Adeline Simionov Alina Mogodan Lacramioara Oprica Victor Cristea Metals are considered to be one of the most hazardous substances due to their potential for accumulation, magnification, persistence, and wide distribution...
Wed Oct 14, 2020 03:00
Molecules, Vol. 25, Pages 4719: Radionuclide Molecular Imaging of EpCAM Expression in Triple-Negative Breast Cancer Using the Scaffold Protein DARPin Ec1 Molecules doi: 10.3390/molecules25204719 Authors: Anzhelika Vorobyeva Ekaterina Bezverkhniaia Elena Konovalova Alexey Schulga Javad Garousi Olga Vorontsova Ayman Abouzayed Anna Orlova Sergey Deyev Vladimir Tolmachev Efficient treatment of disseminated triple-negative breast cancer (TNBC) remains an unmet clinical...
Wed Oct 14, 2020 03:00
Molecules, Vol. 25, Pages 4718: Nile-Red-Based Fluorescence Probe for Selective Detection of Biothiols, Computational Study, and Application in Cell Imaging Molecules doi: 10.3390/molecules25204718 Authors: Xiang Rong Zhong-Yong Xu Jin-Wu Yan Zhi-Zhong Meng Bin Zhu Lei Zhang A new colorimetric and fluorescence probe NRSH based on Nile-red chromophore for the detection of biothiols has been developed, exhibiting high selectivity towards biothiols over other interfering...
Wed Oct 14, 2020 03:00
Molecules, Vol. 25, Pages 4710: Lewis Acid-Facilitated Radiofluorination of MN3PU: A LRRK2 Radiotracer Molecules doi: 10.3390/molecules25204710 Authors: Noeen Malik Shreya Bendre Ralf Schirrmacher Paul Schaffer Background: Temperature-sensitive radiopharmaceutical precursors require lower reaction temperatures (<100 °C) during nucleophilic radiofluorination in order to avoid compound thermolysis, often resulting in sub-optimal radiochemical yields (RCYs). To facilitate...
Wed Oct 14, 2020 03:00
Molecules, Vol. 25, Pages 4716: Formulation and Evaluation of Supramolecular Food-Grade Piperine HP β CD and TPGS Complex: Dissolution, Physicochemical Characterization, Molecular Docking, In Vitro Antioxidant Activity, and Antimicrobial Assessment Molecules doi: 10.3390/molecules25204716 Authors: Syed Sarim Imam Sultan Alshehri Talal Abdullah Alzahrani Afzal Hussain Mohammad A. Altamimi The purpose of the present study was to improve the aqueous solubility, dissolution,...
Wed Oct 14, 2020 03:00
Molecules, Vol. 25, Pages 4720: Inter- vs. Intramolecular Hydrogen Bond Patterns and Proton Dynamics in Nitrophthalic Acid Associates Molecules doi: 10.3390/molecules25204720 Authors: Kinga Jóźwiak Aneta Jezierska Jarosław J. Panek Eugene A. Goremychkin Peter M. Tolstoy Ilya G. Shenderovich Aleksander Filarowski Noncovalent interactions are among the main tools of molecular engineering. Rational molecular design requires knowledge about a result of interplay between...
Wed Oct 14, 2020 03:00
Molecules, Vol. 25, Pages 4706: Developments toward the Implementation of 44Sc Production at a Medical Cyclotron Molecules doi: 10.3390/molecules25204706 Authors: Nicholas P. van der Meulen Roger Hasler Zeynep Talip Pascal V. Grundler Chiara Favaretto Christoph A. Umbricht Cristina Müller Gaia Dellepiane Tommaso S. Carzaniga Saverio Braccini 44Sc has favorable properties for cancer diagnosis using Positron Emission Tomography (PET) making it a promising candidate...
Wed Oct 14, 2020 03:00
Molecules, Vol. 25, Pages 4704: Beneficial Effects of Naringenin in Cigarette Smoke-Induced Damage to the Lung Based on Bioinformatic Prediction and In Vitro Analysis Molecules doi: 10.3390/molecules25204704 Authors: Pan Chen Ziting Xiao Hao Wu Yonggang Wang Weiyang Fan Weiwei Su Peibo Li Naringenin is found mainly in citrus fruits, and is thought to be beneficial in the prevention and control of lung diseases. This study aims to investigate the mechanisms of naringenin...
Wed Oct 14, 2020 03:00
Molecules, Vol. 25, Pages 4714: Characterization of Metabolic Changes under Low Mineral Supply (N, K, or Mg) and Supplemental LED Lighting (Red, Blue, or Red–Blue Combination) in Perilla frutescens Using a Metabolomics Approach Molecules doi: 10.3390/molecules25204714 Authors: Dong Ho Suh Yangmin X. Kim Eun Sung Jung Seulbi Lee Jinyong Park Choong Hwan Lee Jwakyung Sung In order to achieve premium quality with crop production, techniques involving the adjustment of...
Wed Oct 14, 2020 03:00
Molecules, Vol. 25, Pages 4712: Antiangiogenic Activity of Flavonoids: A Systematic Review and Meta-Analysis Molecules doi: 10.3390/molecules25204712 Authors: Khater Greco Osborn Abstract: An imbalance of angiogenesis contributes to many pathologies such as cancer, arthritis and retinopathy, hence molecules that can modulate angiogenesis are of considerable therapeutic importance. Despite many reports on the promising antiangiogenic properties of naturally occurring flavonoids,...
Wed Oct 14, 2020 03:00
Molecules, Vol. 25, Pages 4713: Identification of Polyphenol Glucuronide Conjugates in Glechoma hederacea var. longituba Hot Water Extracts by High-Performance Liquid Chromatography-Tandem Mass Spectrometry (HPLC-MS/MS) Molecules doi: 10.3390/molecules25204713 Authors: Kun Cho Yoon-Ji Choi Yeong Hee Ahn Glechoma hederacea var. longituba (GHL) is one of many herbal plants distributed worldwide and is known to contain various biologically useful antioxidant constituents. GHL has...
Wed Oct 14, 2020 03:00
Molecules, Vol. 25, Pages 4711: Antibacterial, Antifungal, Antimycotoxigenic, and Antioxidant Activities of Essential Oils: An Updated Review Molecules doi: 10.3390/molecules25204711 Authors: Aysegul Mutlu-Ingok Dilara Devecioglu Dilara Nur Dikmetas Funda Karbancioglu-Guler Esra Capanoglu The interest in using natural antimicrobials instead of chemical preservatives in food products has been increasing in recent years. In regard to this, essential oils—natural and...
Wed Oct 14, 2020 03:00
Molecules, Vol. 25, Pages 4715: The Structure and Thermal Properties of Solid Ternary Compounds Forming with Ca2+, Al3+ and Heptagluconate Ions Molecules doi: 10.3390/molecules25204715 Authors: Ákos Buckó Zsolt Kása Márton Szabados Bence Kutus Ottó Berkesi Zoltán Kónya Ákos Kukovecz Pál Sipos István Pálinkó In the present work, the structure and thermal stability of Ca–Al mixed-metal compounds, relevant in the Bayer process as intermediates, have been investigated....
Wed Oct 14, 2020 03:00
Molecules, Vol. 25, Pages 4709: LPS Induces GM-CSF Production by Breast Cancer MDA-MB-231 Cells via Long-Chain Acyl-CoA Synthetase 1 Molecules doi: 10.3390/molecules25204709 Authors: Fatema Al-Rashed Reeby Thomas Areej Al-Roub Fahd Al-Mulla Rasheed Ahmad Granulocyte–macrophage colony-stimulating factor (GM-CSF) is a monomeric glycoprotein that has been implicated in the tumor growth and progression of different types of cancer. GM-CSF is produced by various non-immune...
Wed Oct 14, 2020 03:00
Molecules, Vol. 25, Pages 4699: Antitumor Activity of Ruthenium(II) Terpyridine Complexes towards Colon Cancer Cells In Vitro and In Vivo Molecules doi: 10.3390/molecules25204699 Authors: Maja Savic Aleksandar Arsenijevic Jelena Milovanovic Bojana Stojanovic Vesna Stankovic Ana Rilak Simovic Dejan Lazic Nebojsa Arsenijevic Marija Milovanovic Ruthenium complexes have attracted considerable interest as potential antitumor agents. Therefore, antitumor activity and...
Wed Oct 14, 2020 03:00
Molecules, Vol. 25, Pages 4708: Dihomooxacalix[4]arene-Based Fluorescent Receptors for Anion and Organic Ion Pair Recognition Molecules doi: 10.3390/molecules25204708 Authors: Alexandre S. Miranda Paula M. Marcos José R. Ascenso Mário N. Berberan-Santos Rachel Schurhammer Neal Hickey Silvano Geremia Fluorescent dihomooxacalix[4]arene-based receptors 5a–5c, bearing two naphthyl(thio)ureido groups at the lower rim via a butyl spacer, were synthesised and obtained...
Wed Oct 14, 2020 03:00
Molecules, Vol. 25, Pages 4707: Thymoquinone-Loaded Soluplus®-Solutol® HS15 Mixed Micelles: Preparation, In Vitro Characterization, and Effect on the SH-SY5Y Cell Migration Molecules doi: 10.3390/molecules25204707 Authors: Maria Camilla Bergonzi Marzia Vasarri Giulia Marroncini Emanuela Barletta Donatella Degl’Innocenti Thymoquinone (TQ) is the main active ingredient of Nigella sativa essential oil, with remarkable anti-neoplastic activities with anti-invasive and anti-migratory...
Wed Oct 14, 2020 03:00
Molecules, Vol. 25, Pages 4700: Pyrrolo[3,2-b]pyrrole-1,4-dione (IsoDPP) End Capped with Napthalimide or Phthalimide: Novel Small Molecular Acceptors for Organic Solar Cells Molecules doi: 10.3390/molecules25204700 Authors: Thu Trang Do Meera Stephen Khai Leok Chan Sergei Manzhos Paul L. Burn Prashant Sonar We introduce two novel solution-processable electron acceptors based on an isomeric core of the much explored diketopyrrolopyrrole (DPP) moiety, namely pyrrolo[3,2-b]pyrrole-1,4-dione...
Wed Oct 14, 2020 03:00
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