Αρχειοθήκη ιστολογίου

Αλέξανδρος Γ. Σφακιανάκης
ΩτοΡινοΛαρυγγολόγος
Αναπαύσεως 5
Άγιος Νικόλαος Κρήτη 72100
2841026182
6032607174

Τετάρτη 14 Οκτωβρίου 2020

 


Si-Miao-Yong-An decoction preserves cardiac function and regulates GLC/AMPK/NF-κB and GLC/PPARα/PGC-1α pathways in diabetic mice
Publication date: December 2020Source: Biomedicine & Pharmacotherapy, Volume 132Author(s): Lin Li, Xiangyang Chen, Congping Su, Qing Wang, Rui Li, Wenchao Jiao, Hui Luo, Yimiao Tian, Jiayang Tang, Xiaoxuan Li, Bin Liu, Wei Wang, Dongwei Zhang, Shuzhen Guo
Biomedicine & Pharmacotherapy
Wed Oct 14, 2020 17:09
Simvastatin can enhance the osseointegration of titanium rods in ovariectomized rats maintenance treatment with valproic acid
Publication date: December 2020Source: Biomedicine & Pharmacotherapy, Volume 132Author(s): Zhou-Shan Tao, Wan-Shu Zhou, Hong-Guang Xu, Min Yang
Biomedicine & Pharmacotherapy
Wed Oct 14, 2020 17:09
Melatonin prevents LPS-induced epithelial-mesenchymal transition in human alveolar epithelial cells <em>via</em> the GSK-3β/Nrf2 pathway
Publication date: December 2020Source: Biomedicine & Pharmacotherapy, Volume 132Author(s): Zhenxing Ding, Xu Wu, Yueguo Wang, Shuang Ji, Wenying Zhang, Jiaying Kang, Jiajia Li, Guanghe Fei
Biomedicine & Pharmacotherapy
Wed Oct 14, 2020 17:09
The safety and efficacy of lenvatinib combined with immune checkpoint inhibitors therapy for advanced hepatocellular carcinoma
Publication date: December 2020Source: Biomedicine & Pharmacotherapy, Volume 132Author(s): Yun Wang, Man Jiang, Jingjuan Zhu, Jialin Qu, Kang Qin, Deze Zhao, Li Wang, Lina Dong, Xiaochun Zhang
Biomedicine & Pharmacotherapy
Wed Oct 14, 2020 17:09
A review of traditional Chinese medicine on treatment of diabetic retinopathy and involved mechanisms
Publication date: December 2020Source: Biomedicine & Pharmacotherapy, Volume 132Author(s): Xiaopeng Ai, Peiling Yu, Ya Hou, Xinchen Song, Jie Luo, Ning Li, Xianrong Lai, Xiaobo Wang, Xianli Meng
Biomedicine & Pharmacotherapy
Wed Oct 14, 2020 17:09
The effects of cytarabine combined with ginsenoside compound K synergistically induce DNA damage in acute myeloid leukemia cells
Publication date: December 2020Source: Biomedicine & Pharmacotherapy, Volume 132Author(s): Wenxiu Qi, Xiuci Yan, Xiaohao Xu, Bailin Song, Liping Sun, Daqing Zhao, Liwei Sun
Biomedicine & Pharmacotherapy
Tue Oct 13, 2020 17:02
Visualising functional 5-HT<sub>3</sub> receptors containing A and C subunits at or near the cell surface
Publication date: December 2020Source: Biomedicine & Pharmacotherapy, Volume 132Author(s): Isaiah P.L. Abad, Ray L. Fam, Dan-Thanh Nguyen, Cameron J. Nowell, Phuc N.H. Trinh, David T. Manallack, Lubna A. Freihat, Jay Chakrabarti, Aamani Jamil, Betty Exintaris, Nor S. Yaakob, Helen R. Irving
Biomedicine & Pharmacotherapy
Tue Oct 13, 2020 17:02
The dual protease inhibitor lopinavir/ritonavir (LPV/r) exerts genotoxic stress on lung cells
Publication date: December 2020Source: Biomedicine & Pharmacotherapy, Volume 132Author(s): Rahaba Marima, Rodney Hull, Zodwa Dlamini, Clement Penny
Biomedicine & Pharmacotherapy
Tue Oct 13, 2020 17:02
Anterior gradient 2 is a novel pro-tumor factor in pancreatic cancer under NF-κB subunit RelA trans-regulation that can be suppressed by eugenic acid
Publication date: December 2020Source: Biomedicine & Pharmacotherapy, Volume 132Author(s): Long Huang, Can Yang, Yaodong Wang, Ge Li, Jingjing Pan, Huatian Luo, Zhangwei Wu, Yifeng Tian, Shi Chen, Jiangzhi Chen, Zhixiang Jian
Biomedicine & Pharmacotherapy
Tue Oct 13, 2020 17:02
Panax ginseng clinical trials: Current status and future perspectives
Publication date: December 2020Source: Biomedicine & Pharmacotherapy, Volume 132Author(s): Shasha Fan, Zepeng Zhang, Hang Su, Peng Xu, Hongyu Qi, Daqing Zhao, Xiangyan Li
Biomedicine & Pharmacotherapy
Tue Oct 13, 2020 17:02
Communication between stromal and hematopoietic stem cell by exosomes in normal and malignant bone marrow niche
Publication date: December 2020Source: Biomedicine & Pharmacotherapy, Volume 132Author(s): Vahid Niazi, Benyamin Parseh, Milad Ahani, Farshid Karami, Samira Gilanchi, Kamran Atarodi, Mina Soufi, Masoud Soleimani, Soudeh Ghafouri-Fard, Mohammad Taheri, Hakimeh Zali
Biomedicine & Pharmacotherapy
Tue Oct 13, 2020 17:02
Potential applications of microfluidics based blood brain barrier (BBB)-on-chips for <em>in vitro</em> drug development
Publication date: December 2020Source: Biomedicine & Pharmacotherapy, Volume 132Author(s): Xiaobo Wang, Ya Hou, Xiaopeng Ai, Jiayi Sun, Binjie Xu, Xianli Meng, Yi Zhang, Sanyin Zhang
Biomedicine & Pharmacotherapy
Tue Oct 13, 2020 17:02
Traditional Chinese medicine formulas, extracts, and compounds promote angiogenesis
Publication date: December 2020Source: Biomedicine & Pharmacotherapy, Volume 132Author(s): Lan Bu, Ou Dai, Fei Zhou, Fei Liu, Jin-Feng Chen, Cheng Peng, Liang Xiong
Biomedicine & Pharmacotherapy
Tue Oct 13, 2020 17:02
Digitally‐Enabled, Patient‐Centric Clinical Trials: Shifting the Drug Development Paradigm
Abstract The rapidly advancing field of digital health technologies provides a great opportunity to radically transform the way clinical trials are conducted and to shift the clinical trial paradigm from a site‐centric to a patient‐centric model. Merck & Co., Inc.’s (Kenilworth, NJ, USA) digitally‐enabled clinical trial initiative is focused on introduction of digital technologies into the clinical trial paradigm to reduce patient burden, improve drug adherence, provide a means of more closely...
Clinical and Translational Science
Tue Oct 13, 2020 17:27
Liquid Biopsy of Bile based on Targeted Mass Spectrometry for the Diagnosis of Malignant Biliary Strictures
Abstract Bile holds biomarkers of malignant biliary strictures (MBS) but is unsuited for automated analyzers used in routine diagnostic laboratories. Selected Reaction Monitoring (SRM) is a flexible high‐throughput analytical approach based on targeted mass spectrometry (MS) already implemented in clinical settings. We tested the hypothesis that SRM could be used to quantify cancer biomarkers in human bile. An SRM‐based assay was developed to simultaneously quantify up to 37 peptides from 13 bile...
Clinical and Translational Science
Tue Oct 13, 2020 17:26
Coproporphyrin I Can Serve as an Endogenous Biomarker for OATP1B1 Inhibition: Assessment Using a Glecaprevir/Pibrentasvir Clinical Study
Abstract Organic anion transporting polypeptide (OATP) 1B1 and OATP1B3 are involved in the disposition of a variety of commonly prescribed drugs. The evaluation of OATP1B1/1B3 inhibition potential by investigational drugs is of interest during clinical drug development due to various adverse events associated with increased exposures of their substrates. Regulatory guidance documents on the in vitro assessment of OATP1B1/1B3 inhibition potential are conservative with up to a third of predictions...
Clinical and Translational Science
Tue Oct 13, 2020 17:25
Correlation analysis between the expression of IL‐35, microvessel density, lymphatic vessel density, and prognosis in non‐small cell lung cancer
Abstract The aim of this study was to determine the expression of IL‐35 and the lymphatic vessel density (LVD) and microvessel density (MVD) in the pathological tissues from patients with non‐small cell lung cancer (NSCLC) and to analyze their correlation with other common clinical prognostic factors, as well as patients’ overall survival (OS) and progression‐free survival (PFS). We analyzed the pathological characteristics of 130 patients with NSCLC and determined the IL‐35 expression, MVD, and...
Clinical and Translational Science
Tue Oct 13, 2020 17:24
Retrospective Review of Pharmacogenetic Testing at an Academic Children’s Hospital
Abstract There is limited evidence to support pharmacogenetic testing (PGx) in children. We conducted a retrospective review of PGx among 452 patients at an academic children’s hospital to determine the potential utility of PGx in diseases of childhood and to identify targets for future pediatric pharmacogenetic research. An actionable gene‐drug pair associated with the 28 genes tested (Clinical Pharmacogenetics Implementation Consortium level A or B, Pharmacogenomics Knowledge Base (PharmGKB) level...
Clinical and Translational Science
Tue Oct 13, 2020 17:24
Therapeutic opportunities for intestinal angioectasia‐ targeting PPARγ and oxidative stress
Abstract Recurrent and acute bleeding from intestinal tract angioectasia (AEC) presents a major challenge for clinical intervention. Current treatments are empiric, with frequent poor clinical outcomes. Improvements in understanding the pathophysiology of these lesions will help guide treatment. Using data from FDA’s Adverse Event Reporting System (FAERS) we analyzed 12 million patient reports to identify drugs inversely correlated with GI‐bleeding and potentially limiting AEC severity. FAERS analysis...
Clinical and Translational Science
Tue Oct 13, 2020 17:23
Overview of the pre‐ and post‐marketing requirements for drugs granted Japanese conditional marketing approval
Abstract For drugs that are intended to fill unmet medical needs, such as the treatment of rare diseases or a subtype of cancer, it can take a long time to conduct confirmatory clinical trials due to limited patient availability. Delayed access to these drugs increases the risk of mortality of patients with these diseases. To address this issue, the Ministry of Health, Labour and Welfare of Japan has decided to implement the Conditional Early Approval System with issuing the Ministry Notification...
Clinical and Translational Science
Tue Oct 13, 2020 17:20
Impact of green tea catechin ingestion on the pharmacokinetics of lisinopril in healthy volunteers
Abstract Lisinopril, a highly hydrophilic long‐acting ACE inhibitor, is frequently prescribed for the treatment of hypertension and congestive heart failure. Green tea consumption may reduce the risk of cardiovascular outcomes and total mortality, whereas green tea or its catechin components has been reported to decrease plasma concentrations of a hydrophilic β blocker, nadolol, in humans. The aim of this study was to evaluate possible effects of green tea extract (GTE) on the lisinopril pharmacokinetics....
Clinical and Translational Science
Tue Oct 13, 2020 17:20
Optimizing the Therapeutic Window of Targeted Drugs in Oncology: Potency‐guided First‐in‐Human Studies
Abstract Many targeted therapies are administered at or near the maximum tolerated dose (MTD). With the advent of precision medicine, a larger therapeutic window is expected. Therefore, dose optimization will require a new approach to early clinical trial design. We analyzed publicly available data for 21 therapies targeting six kinases, and four poly (ADP‐ribose) polymerase inhibitors, focusing on potency and exposure to gain insight into dose selection. The free average steady‐state concentration...
Clinical and Translational Science
Tue Oct 13, 2020 17:10
Remote FEV1 monitoring in asthma patients: a pilot study
Abstract Forced expiratory volume in one second (FEV1) is a critical parameter for the assessment of lung function for both clinical care and research in patients with asthma. While asthma is defined by variable airflow obstruction, FEV1 is typically assessed during clinic visits. Mobile spirometry (mSpirometry) allows more frequent measurements of FEV1, resulting in a more continuous assessment of lung function over time and its variability. Twelve patients with moderate asthma were recruited...
Clinical and Translational Science
Tue Oct 13, 2020 16:55
The novel low molecular weight MYC antagonist MYCMI-6 inhibits proliferation and induces apoptosis in breast cancer cells
Summary Background The MYC oncogene is one of the most frequently altered driver genes in cancer. MYC is thus a potential target for cancer treatment as well as a biomarker for the disease. However, as a target for treatment, MYC has traditionally been regarded as “undruggable” or difficult to target. We set out to evaluate the efficacy of a novel MYC inhibitor known as MYCMI-6, which acts by preventing MYC from interacting with its cognate partner MAX. Methods MYCMI-6 response...
Latest Results for Investigational New Drugs
Wed Oct 14, 2020 03:00
A phase Ib study of the highly selective MET-TKI savolitinib plus gefitinib in patients with EGFR -mutated, MET -amplified advanced non-small-cell lung cancer
Summary Epidermal growth factor receptor tyrosine kinase inhibitors (EGFR-TKIs) are recommended first-line treatments in EGFR-mutated (EGFRm) non-small-cell lung cancer (NSCLC). However, acquired resistance (e.g. MET amplification) is frequently observed. Savolitinib (volitinib, HMPL-504, AZD6094) is an oral, potent, and highly selective MET-TKI. In this phase Ib, open-label, multicenter study, we enrolled Chinese patients with EGFRm advanced NSCLC, whose disease progressed following...
Latest Results for Investigational New Drugs
Wed Oct 14, 2020 03:00
Patient-reported outcomes after external beam radiotherapy versus brachytherapy for palliation of dysphagia in esophageal cancer: a matched comparison of two prospective trials
Publication date: Available online 14 October 2020Source: Radiotherapy and OncologyAuthor(s): Peter S.N. van Rossum, Paul M. Jeene, Tom Rozema, Pètra M. Braam, Irene M. Lips, Karin Muller, Daphne van Kampen, Bram D. Vermeulen, Marjolein Y.V. Homs, Vera Oppedijk, Maaike Berbée, Maarten C.C.M. Hulshof, Peter D. Siersema, Sherif Y. El Sharouni
Radiotherapy and Oncology
Wed Oct 14, 2020 15:28
COVID-19 safe and fully operational radiotherapy: an AIRO survey depicting the Italian landscape at the dawn of phase 2
Publication date: Available online 14 October 2020Source: Radiotherapy and OncologyAuthor(s): Barbara Alicja Jereczek-Fossa, Matteo Pepa, Mattia Zaffaroni, Giulia Marvaso, Alessio Bruni, Michela Buglione di Monale e Bastia, Gianpiero Catalano, Andrea Riccardo Filippi, Pierfrancesco Franco, Maria Antonietta Gambacorta, Domenico Genovesi, Giuseppe Iatì, Alessandro Magli, Luigi Marafioti, Icro Meattini, Anna Merlotti, Marcello Mignogna, Daniela Musio, Roberto Pacelli, Stefano Pergolizzi
Radiotherapy and Oncology
Wed Oct 14, 2020 15:28
A qualitative classification signature for post-surgery 5-fluorouracil-based adjuvant chemoradiotherapy in gastric cancer
Publication date: Available online 14 October 2020Source: Radiotherapy and OncologyAuthor(s): Meifeng Li, Haifeng Chen, Jun He, Jiajing Xie, Jie Xia, Hui Liu, Yidan Shi, Zheng Guo, Haidan Yan
Radiotherapy and Oncology
Wed Oct 14, 2020 15:28
Deep learning for elective neck delineation: more consistent and time efficient
Publication date: Available online 14 October 2020Source: Radiotherapy and OncologyAuthor(s): J. Van der Veen, S. Willems, H. Bollen, F. Maes, S. Nuyts
Radiotherapy and Oncology
Wed Oct 14, 2020 15:28
Importance of the ICRU Bladder point dose on incidence and persistence of urinary frequency and incontinence in locally advanced cervical cancer: an EMBRACE analysis
Publication date: Available online 14 October 2020Source: Radiotherapy and OncologyAuthor(s): Sofia Spampinato, Lars U. Fokdal, Richard Pötter, Christine Haie-Meder, Jacob C. Lindegaard, Maximilian P. Schmid, Alina Sturdza, Ina M. Jürgenliemk-Schulz, Umesh Mahantshetty, Barbara Segedin, Kjersti Bruheim, Peter Hoskin, Bhavana Rai, Fleur Huang, Rachel Cooper, Elzbieta van der Steen-Banasik, Erik Van Limbergen, Marit Sundset, Henrike Westerveld, Remi A. Nout
Radiotherapy and Oncology
Wed Oct 14, 2020 15:28
Ureteral Stenosis after 3D MRI-based Brachytherapy for Cervical Cancer – Have We Identified All the Risk Factors?
Publication date: Available online 14 October 2020Source: Radiotherapy and OncologyAuthor(s): Joshua L. Rodríguez-López, Diane C. Ling, Andrew Keller, Hayeon Kim, Adrianna E. Mojica-Márquez, Scott M. Glaser, Sushil Beriwal
Radiotherapy and Oncology
Wed Oct 14, 2020 15:28
Low dose radiation therapy for covid-19: effective dose and estimation of cancer risk
Publication date: Available online 14 October 2020Source: Radiotherapy and OncologyAuthor(s): Trinitat García-Hernández, Maite Romero-Expósito, Beatriz Sánchez Nieto
Radiotherapy and Oncology
Wed Oct 14, 2020 15:28
Results of Phase II Trial of Intensified Neoadjuvant Treatment with Interdigitating Radiotherapy and Chemotherapy with Oxaliplatin, 5-Fluorouracil and Folinic Acid in Patients with Locally Advanced Rectal Cancer (PROARCT trial)
Publication date: Available online 14 October 2020Source: Radiotherapy and OncologyAuthor(s): Sweet Ping Ng, Julie Chu, Sarat Chander, Mathias Bressel, Joseph McKendrick, Rachel Wong, Malcolm Steel, William K Murray, Trevor Leong, Alexander Heriot, Michael Michael, Samuel Y Ngan
Radiotherapy and Oncology
Wed Oct 14, 2020 15:28
From multisource data to clinical decision aids in radiation oncology: the need for a clinical data science community
Publication date: Available online 13 October 2020Source: Radiotherapy and OncologyAuthor(s): Joanna Kazmierska, Andrew Hope, Emiliano Spezi, Sam Beddar, William H. Nailon, Biche Osong, Anshu Ankolekar, Ananya Choudhury, Andre Dekker, Kathrine Røe Redalen, Alberto Traverso
Radiotherapy and Oncology
Wed Oct 14, 2020 15:28
Hypofractionated radiation therapy for breast cancer: preferences amongst radiation oncologists in europe – results from an international survey
Publication date: Available online 13 October 2020Source: Radiotherapy and OncologyAuthor(s): Ivica Ratosa, Monica Emilia Chirilă, Mateja Steinacher, Elvisa Kozma, Radovan Vojtíšek, Pierfrancesco Franco, P. Philip Poortmans
Radiotherapy and Oncology
Wed Oct 14, 2020 15:28
Heart substructural dosimetric parameters and risk of cardiac events after definitive chemoradiotherapy for stage III non-small cell lung cancer
Publication date: Available online 12 October 2020Source: Radiotherapy and OncologyAuthor(s): Bum-Sup Jang, Myung-Jin Cha, Hak Jae Kim, Seil Oh, Hong-Gyun Wu, Eunji Kim, Byoung Hyuck Kim, Jae Sik Kim, Ji Hyun Chang
Radiotherapy and Oncology
Tue Oct 13, 2020 19:28
A qualitative classification signature for post-surgery 5-fluorouracil-based adjuvant chemoradiotherapy in gastric cancer
Gastric cancer (GC) is a malignant tumor [1] with a five-year survival rate of only 20-35% for patients treated with surgery alone [2, 3]. Previous studies have reported that local recurrence and distant metastasis are main causes of poor survival outcomes [4, 5], and 5-fluorouracil (5-FU)-based adjuvant chemoradiotherapy (ACRT) can reduce recurrence rates and improve clinical outcomes [6-10].
Radiotherapy and Oncology
Tue Oct 13, 2020 03:00
Deep learning for elective neck delineation: more consistent and time efficient
Radiotherapy (RT) is one of the cornerstones in the treatment of head and neck cancer (HNC), either alone, after surgery or concomitantly with chemotherapy. Delineation of organs at risk (OARs) and clinical target volumes (CTV) is an important step in the treatment process and is necessary before the treatment plan can be created. This step is typically done manually and is a time-consuming activity. It requires intensive training before it can be done correctly and is susceptible to intra-observer...
Radiotherapy and Oncology
Tue Oct 13, 2020 03:00
Ureteral Stenosis after 3D MRI-based Brachytherapy for Cervical Cancer – Have We Identified All the Risk Factors?
Cervical cancer is the fourth most common cancer in women worldwide and the primary cause of cancer-related deaths among women in low- and middle-income countries [1]. Chemoradiation followed by brachytherapy (BT) boost is the standard of care for patients with node-positive and/or locally advanced cervical cancer [2-5]. In the last few decades, there has been an evolution of BT planning from 2-dimensional (2D) point-based prescribing to 3-dimensional (3D)-computed tomography (CT) and most recently,...
Radiotherapy and Oncology
Tue Oct 13, 2020 03:00
Results of Phase II Trial of Intensified Neoadjuvant Treatment with Interdigitating Radiotherapy and Chemotherapy with Oxaliplatin, 5-Fluorouracil and Folinic Acid in Patients with Locally Advanced Rectal Cancer (PROARCT trial)
Preoperative radiotherapy and total mesorectal excision (TME) have significantly reduced the risk of locoregional recurrence in rectal cancer. Local failure rate has been reduced to less than 10% with preoperative chemoradiotherapy. Distant metastatic disease is now the predominant site of recurrence following curative-intent therapy with 30% of patients with T3 primary tumour developing distant recurrence despite the use of adjuvant chemotherapy [1-3]. In the pursuit of improving overall survival...
Radiotherapy and Oncology
Tue Oct 13, 2020 03:00
Patient-reported outcomes after external beam radiotherapy versus brachytherapy for palliation of dysphagia in esophageal cancer: a matched comparison of two prospective trials
A matched comparison of external beam radiotherapy (EBRT) versus brachytherapy recently demonstrated that EBRT appears at least as effective for palliating dysphagia in patients with incurable esophageal cancer. The aim of this analysis was to compare patient-reported outcomes (PROs) after EBRT versus brachytherapy.
Radiotherapy and Oncology
Tue Oct 13, 2020 03:00
Importance of the ICRU Bladder point dose on incidence and persistence of urinary frequency and incontinence in locally advanced cervical cancer: an EMBRACE analysis
Late morbidity after pelvic radiotherapy includes urinary side effects which may significantly impact patients quality of life (QoL) [1]. For locally advanced cervical cancer (LACC), the introduction of image-guided adaptive brachytherapy (IGABT) has led to a decrease in side effects compared to two-dimensional brachytherapy (BT) [2,3]. Disease control and overall survival are improved [4], but urinary morbidity still represents a burden for cancer survivors [5].
Radiotherapy and Oncology
Tue Oct 13, 2020 03:00
Low dose radiation therapy for covid-19: effective dose and estimation of cancer risk
The objective of this work is to evaluate the risk of carcinogenesis of low dose ionizing radiation therapy (LDRT), for treatment of immune-related pneumonia following COVID-19 infection, through the estimation of effective dose and the lifetime attributable risk of cancer (LAR).
Radiotherapy and Oncology
Tue Oct 13, 2020 03:00
COVID-19 safe and fully operational radiotherapy: an AIRO survey depicting the Italian landscape at the dawn of phase 2
Italy was the first European country heavily involved in the COrona VIrus Disease 19 (COVID-19) pandemic 1, with 294,932 cases and more than 35,000 deaths as of 18th September 2020 2. Despite the severity of the pandemic in the so-called Italian phase (P) 1 (18th March - 3rd May 2020), radiation therapy (RT) facilities in the country managed to efficiently reorganized themselves to maintain a high standard of care while minimizing the risk of contagion for patients and staff 3. The safety measures...
Radiotherapy and Oncology
Tue Oct 13, 2020 03:00
Hypofractionated radiation therapy for breast cancer: preferences amongst radiation oncologists in europe – results from an international survey
Breast cancer (BC) is the most common cancer in women [1], and post-operative radiation therapy (RT) is a fundamental part of treatment after either conservative surgery or mastectomy [2–4]. BC ranks as the first amongst all cancer types with respect to the absolute numbers of RT indications needed in the forthcoming years in more than half of the European countries [5]. Furthermore, it has been estimated that the number of RT courses for BC patients in Europe will increase on average by 10.1% from...
Radiotherapy and Oncology
Tue Oct 13, 2020 03:00
From multisource data to clinical decision aids in radiation oncology: the need for a clinical data science community
Many large commercial enterprises are redirecting their business approaches to exploit the new knowledge they can gain from the data they collect daily. This strategy arose from the need to mine a large amount of diverse data, often unstructured and coming from multiple sources: so-called “big data.” Whereas initially big data seemed to present an obstacle, now it is becoming more evident that leveraging massive data collections using novel techniques can reveal previously undiscovered knowledge...
Radiotherapy and Oncology
Tue Oct 13, 2020 03:00
Identification and verification immune-related regulatory network in acne
Publication date: December 2020Source: International Immunopharmacology, Volume 89, Part BAuthor(s): Yuan Xin, Shuping Zhang, Zhili Deng, Dandan Zeng, Ji Li, Yiya Zhang
ScienceDirect Publication: International Immunopharmacology
Wed Oct 14, 2020 18:09
Protective effects of egg yolk immunoglobulins (IgYs) developed against recombinant immunogens CtxB, OmpW and TcpA on infant mice infected with <em>Vibrio cholerae</em>
Publication date: December 2020Source: International Immunopharmacology, Volume 89, Part BAuthor(s): Fatemeh Taheri, Shahram Nazarian, Tooba Sadat Ahmadi, Seyed Latif Mousavi Gargari
ScienceDirect Publication: International Immunopharmacology
Wed Oct 14, 2020 18:09
Puerarin protects against myocardial ischemia/reperfusion injury by inhibiting inflammation and the NLRP3 inflammasome: The role of the SIRT1/NF-κB pathway
Publication date: December 2020Source: International Immunopharmacology, Volume 89, Part BAuthor(s): Zi-Kuan Wang, Rui-Rui Chen, Jing-Hua Li, Jing-Yuan Chen, Wei Li, Xiao-Lin Niu, Fang-Fang Wang, Jing Wang, Jing-Xiao Yang
ScienceDirect Publication: International Immunopharmacology
Wed Oct 14, 2020 18:09
Subcutaneous tocilizumab in adults with severe and critical COVID-19: a prospective open-label uncontrolled multicenter trial
Publication date: Available online 13 October 2020Source: International ImmunopharmacologyAuthor(s): Reza Malekzadeh, Atefeh Abedini, Behzad Mohsenpour, Ehsan Sharifipour, Roya Ghasemian, Seyed Ali Javad-Mousavi, Rozita Khodashahi, Mahboobeh Darban, Saeed Kalantari, Nafiseh Abdollahi, Mohammad Reza Salehi, Abbas Rezaei Hosseinabadi, Farzin Khorvash, Melika Valizadeh, Farzaneh Dastan, Sahar Yousefian, Hamed Hosseini, Nassim Anjidani, Payam Tabarsi
ScienceDirect Publication: International Immunopharmacology
Wed Oct 14, 2020 18:09
Chimeric antigen receptor T cell therapy and nephrotoxicity: From diagnosis to treatment strategies
Publication date: December 2020Source: International Immunopharmacology, Volume 89, Part BAuthor(s): Hua Zhou, Min Yang, Li Cui, Jingting Jiang
ScienceDirect Publication: International Immunopharmacology
Tue Oct 13, 2020 18:03
miR-146a-5p improves the decidual cytokine microenvironment by regulating the toll-like receptor signaling pathway in unexplained spontaneous abortion
Publication date: December 2020Source: International Immunopharmacology, Volume 89, Part BAuthor(s): Hong-xia Ye, Lan Li, Ya-jun Dong, Peng-hao Li, Qin Su, Yan-hua Guo, Yan-rong Lu, Ying Zhong, Yan Jia, Jing-qiu Cheng
ScienceDirect Publication: International Immunopharmacology
Tue Oct 13, 2020 18:03
Toll-like receptors in sepsis-associated cytokines storm and their endogenous negative regulators as future immunomodulatory targets
Publication date: Available online 12 October 2020Source: International ImmunopharmacologyAuthor(s): V. Kumar
ScienceDirect Publication: International Immunopharmacology
Tue Oct 13, 2020 18:03
Nucleic acid and antibody assay results in Chinese patients with coronavirus disease 2019 (COVID-19)
Publication date: December 2020Source: International Immunopharmacology, Volume 89, Part BAuthor(s): Yong Lu, Yongyan Li, Yiping Wang, Jianping Luo, Wanjun Yu
ScienceDirect Publication: International Immunopharmacology
Wed Oct 14, 2020 18:09
Part 3-Developmental Stage: The Cornerstone of training
Publication date: Available online 14 October 2020Source: Journal of Bodywork and Movement TherapiesAuthor(s): Nicole Rodriguez, Craig Liebenson D.C, Fred Duncan
ScienceDirect Publication: Journal of Bodywork and Movement Therapies
Wed Oct 14, 2020 15:13
PILATES TRAINING IMPROVES AEROBIC CAPACITY, BUT NOT LIPID OR LIPOPROTEIN LEVELS IN ELDERLY WOMEN WITH DYSLIPIDEMIA: A CONTROLLED TRIAL
Publication date: Available online 13 October 2020Source: Journal of Bodywork and Movement TherapiesAuthor(s): Adriana Cristine Koch BUTTELLI, Rochelle Rocha COSTA, Juliano Boufleur FARINHA, Alex de Oliveira FAGUNDES, Alexandra Ferreira VIEIRA, Bruna Machado BARROSO, Cláudia Gomes BRACHT, Leandro COCONCELLI, Thaís REICHERT, Vitoria de Mello Bones da ROCHA, Luiz Fernando Martins KRUEL
ScienceDirect Publication: Journal of Bodywork and Movement Therapies
Wed Oct 14, 2020 15:13
PROXIMAL AND DISTAL MUSCLE THICKNESS IS DIFFERENT IN WOMEN WITH PATELLOFEMORAL PAIN BUT IS NOT ASSOCIATED WITH KNEE FRONTAL PLANE PROJECTION ANGLE
Publication date: Available online 13 October 2020Source: Journal of Bodywork and Movement TherapiesAuthor(s): Rodrigo Rodrigues, Emmanuel Souza da Rocha, Kelli Daiana Klein, Francesca Chaida Sonda, Klauber Dalcero Pompeo, Viviane Bortoluzzi Frasson, Marco Aurélio Vaz
ScienceDirect Publication: Journal of Bodywork and Movement Therapies
Wed Oct 14, 2020 15:13
Accuracy of rib palpation for dry needling of deep periscapular musculature, measured with ultrasound
Publication date: Available online 13 October 2020Source: Journal of Bodywork and Movement TherapiesAuthor(s): Daniel M. Cushman, Linda Vernon Scholl, Monica Ludlow, Shellie Cunningham, Masaru Teramoto
ScienceDirect Publication: Journal of Bodywork and Movement Therapies
Wed Oct 14, 2020 15:13
Accuracy of the step test to evaluate lower limb muscle strength in community-dwelling older women
Publication date: Available online 13 October 2020Source: Journal of Bodywork and Movement TherapiesAuthor(s): Jaqueline Mello Porto, Renato Campos Freire Júnior, Luciana Mendes Cangussu-Oliveira, Erika Leitner, Lara Gonçalves Freitas, Bruna Garcia Medeiros de Oliveira, Patrícia Silva Tofani, Daniela Cristina Carvalho de Abreu
ScienceDirect Publication: Journal of Bodywork and Movement Therapies
Wed Oct 14, 2020 15:13
Direct Measurement of the Rhythmic Motions of the Human Head Identifies a Third Rhythm
Publication date: Available online 13 October 2020Source: Journal of Bodywork and Movement TherapiesAuthor(s): Thomas Rosenkilde Rasmussen, Karl Christian Meulengracht
ScienceDirect Publication: Journal of Bodywork and Movement Therapies
Wed Oct 14, 2020 15:13
Antimicrobial effects of photodynamic therapy on <em>Staphylococcus aureus</em> biofilm grown on a specific acrylic resin surface for ocular prostheses
Publication date: December 2020Source: Photodiagnosis and Photodynamic Therapy, Volume 32Author(s): Nayane de Lanes Gonçalves, Vinícius Martins Borges, José Alcides Almeida de Arruda, Emerson Gomes dos Santos, Ivana Márcia Alves Diniz, Mila Fernandes Moreira Madeira, Amália Moreno
ScienceDirect Publication: Photodiagnosis and Photodynamic Therapy
Wed Oct 14, 2020 18:37
Comparison of actual and simulated tumoricidal effects induced by photodynamic therapy
Publication date: Available online 13 October 2020Source: Photodiagnosis and Photodynamic TherapyAuthor(s): Wendong Jin, Xiafei Shi, Huijuan Yin, Haixia Zhang, Zhiyuan Wang, Qianqian Chen, Hongjun Wu, Yu Han, Yinxin Li
ScienceDirect Publication: Photodiagnosis and Photodynamic Therapy
Wed Oct 14, 2020 18:37
In vitro antimicrobial effect of curcumin-based photodynamic therapy on Porphyromonas gingivalis and Aggregatibacter actinomycetemcomitans
Publication date: Available online 13 October 2020Source: Photodiagnosis and Photodynamic TherapyAuthor(s): Hui Pan, Dongqing Wang, Fengqiu Zhang
ScienceDirect Publication: Photodiagnosis and Photodynamic Therapy
Wed Oct 14, 2020 18:37
Quantitative light-induced fluorescence as a potential tool for detection of enamel chemical composition
Publication date: Available online 13 October 2020Source: Photodiagnosis and Photodynamic TherapyAuthor(s): Joo-Young Lee, Hyo-Jung Kim, Eun-Song Lee, Elbert de Josselin de Jong, Hoi-In Jung, Baek-Il Kim
ScienceDirect Publication: Photodiagnosis and Photodynamic Therapy
Wed Oct 14, 2020 18:37
Assessment of Retinal Vessel Density in Adult-Onset Foveomacular Vitelliform Dystrophy by Optical Coherence Tomography Angiography
Publication date: Available online 13 October 2020Source: Photodiagnosis and Photodynamic TherapyAuthor(s): Ozge Pinar Akarsu Acar, Ismail Umut Onur, Fatma Selin Kaya, Bengi Demirayak, Fadime Ulviye Yigit
ScienceDirect Publication: Photodiagnosis and Photodynamic Therapy
Wed Oct 14, 2020 18:37
Photocatalytic, antiproliferative and antimicrobial properties of Copper nanoparticles synthesized using <em>Manilkara zapota</em> leaf extract: A photodynamic approach
Publication date: Available online 13 October 2020Source: Photodiagnosis and Photodynamic TherapyAuthor(s): Rose Mary Kiriyanthan, S. Aruna Sharmili, R. Balaji, S. Jayashree, Shahid Mahboob, Khalid A. Al-Ghanim, Fahad Al-Misned, Zubair Ahmed, Marimuthu Govindarajan, Baskaralingam Vaseeharan
ScienceDirect Publication: Photodiagnosis and Photodynamic Therapy
Wed Oct 14, 2020 18:37
Antimicrobial capacity of photodynamic therapy on oral health-related quality of life and halitosis among elderly patients wearing removal dentures
Publication date: Available online 13 October 2020Source: Photodiagnosis and Photodynamic TherapyAuthor(s): Nawaf Labban, Mansour K. Assery, Reem Al-Kattan, Nouf Al-Shibani, Afnan F. Alfouzan, Sara Mohammad Al Taweel
ScienceDirect Publication: Photodiagnosis and Photodynamic Therapy
Wed Oct 14, 2020 18:37
The influence of violet LED light on tooth bleaching protocols: in vitro study of bleaching effectiveness
Publication date: Available online 12 October 2020Source: Photodiagnosis and Photodynamic TherapyAuthor(s): Thaiany Wendy Silva Daltro, Suênia Andressa Gomes de Almeida, Marlon Ferreira Dias, Paulo Cardoso Lins-Filho, Claudio Heliomar Vicente da Silva, Renata Pedrosa Guimarães
ScienceDirect Publication: Photodiagnosis and Photodynamic Therapy
Tue Oct 13, 2020 12:24
Synthesis, characterization, photodynamic activity of half-sandwich rhodium(III) complexes with curcuminoids
Publication date: Available online 12 October 2020Source: Photodiagnosis and Photodynamic TherapyAuthor(s): Baoqu Zhang, Jun’an Xiao, Xiaohui Wang, Peiyuan Li, Wei Su
ScienceDirect Publication: Photodiagnosis and Photodynamic Therapy
Tue Oct 13, 2020 12:24
Treatment of infected wounds with methylene blue photodynamic therapy: An effective and safe treatment method
Publication date: Available online 12 October 2020Source: Photodiagnosis and Photodynamic TherapyAuthor(s): Xiaoxiao Shen, Liwen Dong, Xuan He, Chuanqi Zhao, Wanqi Zhang, Xinying Li, Yuangang Lu
ScienceDirect Publication: Photodiagnosis and Photodynamic Therapy
Tue Oct 13, 2020 12:24

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