Sex/gender modifies the association between the MC4R p.Ile269Asn mutation and type 2 diabetes in the Mexican population. J Clin Endocrinol Metab. 2020 Oct 13;: Authors: Vázquez-Moreno M, Locia-Morales D, Valladares-Salgado A, Sharma T, Wacher-Rodarte N, Cruz M, Meyre D Abstract CONTEXT: Studies in mice and humans suggest that melanocortin-4 receptor (MC4R) deficiency impacts body weight in a sex/gender-dependent manner. However, similar evidence...
Wed Oct 14, 2020 00:44
Aural Myiasis: A Case Report and Literature Review. Ear Nose Throat J. 2020 Oct 13;:145561320966072 Authors: Wang Y, Sun Y, Kong W, Wang Y Abstract Myiasis is a type of parasitosis caused by the larvae of diptera. It commonly occurs in tropical and subtropical zones. The infestation of nose and ears can be extremely dangerous if the larvae destroy the bone and penetrate into the brain, in which case the fatality rate is reported to be...
Wed Oct 14, 2020 21:08
Actinomycosis: An Unusual Cause of Maxillary Sinusitis. Ear Nose Throat J. 2020 Oct 13;:145561320965207 Authors: Varghese L, Cherian LM, Varghese GM PMID: 33048586 [PubMed - as supplied by publisher]
Wed Oct 14, 2020 21:08
Tenosynovial Giant Cell Tumor of the Retropharynx: A Case Report With Literature Review. Ear Nose Throat J. 2020 Oct 13;:145561320966069 Authors: Liu G, Liu F Abstract Tenosynovial giant cell tumor (TSGCT) represents a family of benign tumors that arise from the synovial tissue of a joint, tendon sheath, or bursa. It usually involves the joints of the extremities and rarely occurs in the head and neck region. Here, we describe a case of...
Wed Oct 14, 2020 21:08
The Differences Between 2 Cases of Preauricular Fistula. Ear Nose Throat J. 2020 Oct 13;:145561320966071 Authors: Cho YJ, Min HJ, Kim KS PMID: 33048577 [PubMed - as supplied by publisher]
Wed Oct 14, 2020 21:08
Masseter Flap for Reconstruction of Defects After Excision of Buccal Mucosa Cancers with Intact Mandible. Ear Nose Throat J. 2020 Oct 13;:145561320963442 Authors: Chaturvedi P, Lerra S, Ustad F, Pai PS, Chaukar DA, D'Cruz AK Abstract Among the reconstructive options available for buccal mucosa defects with an intact mandible, free flap with microvascular anastomosis is the best option. However, in the developing world, with poor resources,...
Wed Oct 14, 2020 21:08
Useful Extension of a Retroauricular Hairline Incision in a Parotidectomy Provides Coverage of a Preauricular Skin Defect. Ear Nose Throat J. 2020 Oct 13;:145561320957509 Authors: Shin JY, Seo DH, Roh SG, Lee NH Abstract This report outlines the treatment of an 82-year-old man with squamous cell carcinoma of the left cheek. The wide excision and simultaneous superficial parotidectomy were planned. Various incision methods have been widely...
Wed Oct 14, 2020 21:08
Lasers in Tonsillectomy: Revisited With Systematic Review. Ear Nose Throat J. 2020 Oct 13;:145561320961747 Authors: Ahmed J, Arya A Abstract INTRODUCTION: In 2005, the National Prospective Tonsillectomy Audit was conducted by the Royal College of Surgeons England, reporting hot tonsillectomy techniques being associated with more postoperative pain and hemorrhage when compared with dissection. In 2006, the National Institute of Clinical...
Wed Oct 14, 2020 21:08
Unilateral Maxillary Sinus Plasmablastic Lymphoma in an Immunocompetent Patient. An Unusual Occurrence Report and Literature Review. Ear Nose Throat J. 2020 Oct 12;:145561320963715 Authors: Chicuellar NR, Sufyan W, Mahendran S Abstract Plasmablastic lymphoma (PBL) is a rare and aggressive form of mature B cell neoplasms almost exclusively identified in patients infected with the human immunodeficiency virus (HIV). The small number of HIV-negative...
Tue Oct 13, 2020 21:36
Montgomery Salivary Bypass Tube in Head and Neck Cancer: The Experience of Our Otolaryngology Clinic. Ear Nose Throat J. 2020 Oct 12;:145561320961754 Authors: Minni A, Ralli M, Di Cianni S, Cialente F, Candelori F, Colizza A, Cambria F, de Vincentiis M Abstract INTRODUCTION: One of the most common complications in the immediate and late postoperative period following total laryngectomy or pharyngolaryngectomy is pharyngocutaneous fistulae...
Tue Oct 13, 2020 21:36
Extramedullary Plasmacytoma of Nasal Cavity: A Case Report and Literature Review. Ear Nose Throat J. 2020 Oct 12;:145561320960005 Authors: Hu X, Peng C, Wang P, Cai J Abstract Extramedullary plasmacytoma (EMP) is a tumor characterized by plasma cell proliferation in organs or tissues outside the bone marrow. It originates from B lymphocytes and can occur in all extramedullary tissues and organs of the body. Primary EMPs of the nasal cavity...
Tue Oct 13, 2020 21:36
Relationship between Dysarthria and Oral-Oropharyngeal Dysphagia: The present evidence. Ear Nose Throat J. 2020 Oct 12;:145561320951647 Authors: Wang BJ, Carter FL, Altman KW Abstract There is a high prevalence of dysphagia in patients with neuromuscular diseases and stroke, and consequences can be profound. However, the correlation of dysarthria and oral-oropharyngeal dysphagia remains unclear. This review aimed to define the clinical...
Tue Oct 13, 2020 21:36
105 new pubmed citations were retrieved for your search. Click on the search hyperlink below to display the complete search results: head and neck These pubmed results were generated on 2020/10/14PubMed comprises more than millions of citations for biomedical literature from MEDLINE, life science journals, and online books. Citations may include links to full-text content from PubMed Central and publisher web sites.
Wed Oct 14, 2020 20:57
Asymmetrical effects of deafness-associated mitochondrial DNA 7516delA mutation on the processing of RNAs in the H-strand and L-strand polycistronic transcripts. Nucleic Acids Res. 2020 Oct 12;: Authors: Xiao Y, Wang M, He Q, Xu L, Zhang Q, Meng F, Jia Z, Zhang F, Wang H, Guan MX Abstract In this report, we investigated the molecular mechanism underlying a deafness-associated m.7516delA mutation affecting the 5' end processing sites of...
Tue Oct 13, 2020 21:27
Prospective evaluation of the prognostic value of immune-related adverse events in patients with non-melanoma solid tumour treated with PD-1/PD-L1 inhibitors alone and in combination with radiotherapy. Eur J Cancer. 2020 Oct 08;140:55-62 Authors: Schweizer C, Schubert P, Rutzner S, Eckstein M, Haderlein M, Lettmaier S, Semrau S, Gostian AO, Frey B, Gaipl US, Zhou JG, Fietkau R, Hecht M Abstract BACKGROUND: Prospective data about the prognostic...
Tue Oct 13, 2020 21:27
Frailty is associated with decline in health-related quality of life of patients treated for head and neck cancer. Oral Oncol. 2020 Oct 09;111:105020 Authors: de Vries J, Bras L, Sidorenkov G, Festen S, Steenbakkers RJHM, Langendijk JA, Witjes MJH, van der Laan BFAM, de Bock GH, Halmos GB Abstract OBJECTIVE: To determine the effect of frailty on Health Related Quality of Life (HRQoL) after treatment for Head and Neck Cancer (HNC). ...
Tue Oct 13, 2020 21:27
The role of fine needle aspiration biopsy in deep lobe parotid tumors: Comparison of preoperative cytology and postoperative histopathologic results. Am J Otolaryngol. 2020 Jun 10;42(1):102590 Authors: Seyhun N, Doğan U, Çalış ZAB, Kaya MF, Hasçiçek SÖ, Turgut S Abstract PURPOSE: Major salivary gland tumors constitute almost 3% of head and neck tumors. Tumors located exclusively in the deep lobe are not common and 20% of parotid gland...
Tue Oct 13, 2020 21:27
Targeting methyltransferase PRMT5 retards the carcinogenesis and metastasis of HNSCC via epigenetically inhibiting Twist1 transcription. Neoplasia. 2020 Oct 09;22(11):617-629 Authors: Fan Z, He L, Li M, Cao R, Deng M, Ping F, Liang X, He Y, Wu T, Tao X, Xu J, Cheng B, Xia J Abstract Protein arginine methyltransferase 5 (PRMT5) is an important type II arginine methyltransferase that can play roles in cancers in a highly tissue-specific...
Tue Oct 13, 2020 21:27
LINC00922 regulates epithelial-mesenchymal transition, invasive and migratory capacities in breast cancer through promoting NKD2 methylation. Cell Signal. 2020 Oct 09;:109808 Authors: Wang Y, Dong T, Wang P, Li S, Wu G, Zhou J, Wang Z Abstract Breast cancer ranks as the major reason for mortality in women populations, accounting for 23% of all cancer deaths. One in every three Asian women encounters the risk of this cancer in their lifetime....
Tue Oct 13, 2020 21:27
Guided Endodontic Access in a Maxillary Molar Using a Dynamic 3D Navigation System: A Case Report. J Endod. 2020 Oct 09;: Authors: Dianat O, Gupta S, Price JB, Mostoufi B Abstract Treatment of calcified root canals is challenging in endodontic practice. A 63 year-old male was referred to the postgraduate endodontic clinic at the University of Maryland School of Dentistry (UMSOD) for treatment of tooth #3. Due to the patient's history of...
Tue Oct 13, 2020 21:27
A follow-up study of a Chinese family with Waardenburg syndrome type II caused by a truncating mutation of MITF gene. Mol Genet Genomic Med. 2020 Oct 12;:e1520 Authors: Yang S, Wang C, Zhou C, Kang D, Zhang X, Yuan H Abstract BACKGROUND: Waardenburg syndrome (WS) is a highly clinically and genetically heterogeneous disease. The core disease phenotypes of WS are sensorineuronal hearing loss and pigmentary disturbance, which are usually...
Tue Oct 13, 2020 21:27
Double-blinded randomized prospective trial of intranasal capsaicin treatment for nonallergic rhinitis. Int Forum Allergy Rhinol. 2020 Jul 07;: Authors: Zebda D, Jiang ZY, Gibson MM, Pham C, Ahmadi S, Floren S, Yao WC, Citardi MJ, Luong AU Abstract BACKGROUND: Nonallergic rhinitis (NAR) is currently a diagnosis of exclusion with an unclear pathophysiologic mechanism and limited treatment options. In patients diagnosed with NAR based on...
Tue Oct 13, 2020 21:27
Unilateral Maxillary Sinus Plasmablastic Lymphoma in an Immunocompetent Patient. An Unusual Occurrence Report and Literature Review. Ear Nose Throat J. 2020 Oct 12;:145561320963715 Authors: Chicuellar NR, Sufyan W, Mahendran S Abstract Plasmablastic lymphoma (PBL) is a rare and aggressive form of mature B cell neoplasms almost exclusively identified in patients infected with the human immunodeficiency virus (HIV). The small number of HIV-negative...
Tue Oct 13, 2020 21:27
Montgomery Salivary Bypass Tube in Head and Neck Cancer: The Experience of Our Otolaryngology Clinic. Ear Nose Throat J. 2020 Oct 12;:145561320961754 Authors: Minni A, Ralli M, Di Cianni S, Cialente F, Candelori F, Colizza A, Cambria F, de Vincentiis M Abstract INTRODUCTION: One of the most common complications in the immediate and late postoperative period following total laryngectomy or pharyngolaryngectomy is pharyngocutaneous fistulae...
Tue Oct 13, 2020 21:27
Salivary Gland Tumors: A Retrospective Study of 164 Cases from a Single Private Practice Service in Mexico and Literature Review. Head Neck Pathol. 2020 Oct 12;: Authors: Cunha JLS, Hernandez-Guerrero JC, de Almeida OP, Soares CD, Mosqueda-Taylor A Abstract Salivary gland tumors (SGT) represent an uncommon heterogeneous group of tumors with complex clinical and pathological characteristics. The prevalence of these lesions varies between...
Tue Oct 13, 2020 21:27
Immune microenvironment of the gene signature reflecting the standardised uptake value on 18F-fluorodeoxyglucose positron emission tomography/computed tomography in head and neck squamous cell carcinoma. Ann Nucl Med. 2020 Oct 12;: Authors: Han S, Oh JS, Kim JS Abstract OBJECTIVE: A comprehensive understanding of the link between 18F-FDG PET/CT and the tumor immune microenvironment (TIM) is lacking. We, therefore, investigated the TIM...
Tue Oct 13, 2020 21:27
Pearls on resecting the TMJ chondrosarcoma: how i do it. Eur Arch Otorhinolaryngol. 2020 Oct 12;: Authors: Chia ZJ, Gan YJ, Lim MY Abstract BACKGROUND: Chondrosarcoma of the head and neck is uncommon and Chondrosarcoma of the Temporomandibular Joint is exceedingly rare. We present a 67-year-old male with a large right TMJ Chondrosarcoma. METHODS: Patient underwent right segmental mandibulectomy with excision of TMJ tumor, lateral...
Tue Oct 13, 2020 21:27
[Mutation signatures in head and neck squamous cell carcinoma : Pathogenesis and therapeutic potential]. HNO. 2020 Oct 12;: Authors: Plath M, Hess J, Zaoui K Abstract BACKGROUND: The pathogenesis of head and neck squamous cell carcinoma (HNSCC) is a complex and multistage process which results from the interaction of exogenous and endogenous cellular processes. Each of these processes leaves a characteristic pattern of mutations on the...
Tue Oct 13, 2020 21:27
Management of transmodiolar and transmacular cochleovestibular schwannomas with and without cochlear implantation. HNO. 2020 Oct 12;: Authors: Plontke SK, Caye-Thomasen P, Strauss C, Kösling S, Götze G, Siebolts U, Vordermark D, Wagner L, Fröhlich L, Rahne T Abstract INTRODUCTION: Hearing rehabilitation with cochlear implants has attracted increasing interest also for patients with cochleovestibular schwannoma. The authors report their...
Tue Oct 13, 2020 21:27
Clinical Evidence Supporting US Food and Drug Administration Clearance of Novel Therapeutic Devices via the De Novo Pathway Between 2011 and 2019. JAMA Intern Med. 2020 Oct 12;: Authors: Johnston JL, Dhruva SS, Ross JS, Rathi VK PMID: 33044513 [PubMed - as supplied by publisher]
Tue Oct 13, 2020 21:27
A Study of Correlation Between Tympanic Membrane Perforation Size With Hearing Loss in Patients With Inactive Mucosal Chronic Otitis Media. Otol Neurotol. 2020 Oct 09;: Authors: Kolluru K, Kumar S, Upadhyay P Abstract PURPOSE: This study is directed towards establishing a correlation between the objective measurement of tympanic membrane (TM) perforation size with hearing loss in patients with inactive mucosal chronic otitis media (COM),...
Tue Oct 13, 2020 21:27
Bilateral Sequential Spontaneous Otogenic Pneumocephalus, Lessons in Pathophysiology, and Management of a Rare Case. Otol Neurotol. 2020 Oct 09;: Authors: Shapiro SB, Lipschitz N, Tumlin P, Krueger B, Forbes J, Samy RN Abstract OBJECTIVE: Report the details of an unusual case of initially unilateral intradural spontaneous otogenic pneumocephalus in which the patient developed contralateral pneumocephalus after surgical repair of temporal...
Tue Oct 13, 2020 21:27
Treatment of Oligometastatic Disease in Squamous Cell Carcinoma of the Head and Neck. Laryngoscope. 2020 Oct 12;: Authors: Vincent AG, Wang W, Shokri T, Ducic Y Abstract OBJECTIVE: No surgical or radiotherapeutic treatment guidelines exist for oligometastatic head and neck squamous cell carcinoma (oHNSCC), and only recently have interventions with curative intent been studied. Herein, we sought to elucidate survival rates among patients...
Tue Oct 13, 2020 21:27
Office-Based Procedure Training in Laryngology Fellowship Programs. Laryngoscope. 2020 Oct 12;: Authors: Enver N, Ramaswamy A, Sulica L, Pitman MJ Abstract OBJECTIVE: To assess the current practices and challenges of training office-based procedures to laryngology fellows in the United States. METHODS: An anonymous web-based survey study was distributed to laryngology fellowship program directors, as listed by the American Laryngological...
Tue Oct 13, 2020 21:27
Trimers Conjugated to Fibrin Hydrogels Promote Salivary Gland Function. J Dent Res. 2020 Oct 10;:22034520964784 Authors: Dos Santos HT, Nam K, Brown CT, Dean SM, Lewis S, Pfeifer CS, Lei P, Petris MJ, Andreadis ST, Baker OJ Abstract New strategies for tissue engineering have great potential for restoring and revitalizing impaired tissues and organs, including the use of smart hydrogels that can be modified to enhance organization and functionality...
Tue Oct 13, 2020 21:27
Simultaneous bilateral stapes surgery after follow-up of 13 years. Acta Otolaryngol. 2020 Oct 12;:1-4 Authors: Jutila T, Sivonen V, Hirvonen TP Abstract BACKGROUND: Eighteen patients underwent simultaneous bilateral stapes surgery in 2003-2006. OBJECTIVES: We evaluated the long-term outcomes in this patient group, and assessed their hearing in noise and binaural hearing. MATERIAL AND METHODS: Fifteen patients returned...
Tue Oct 13, 2020 21:27
Long non-coding RNA ELDR enhances oral cancer growth by promoting ILF3-cyclin E1 signaling. EMBO Rep. 2020 Oct 12;:e51042 Authors: Sur S, Nakanishi H, Steele R, Zhang D, Varvares MA, Ray RB Abstract Oral squamous cell carcinoma (OSCC) is the sixth most common cancer with a 5-year overall survival rate of 50%. Thus, there is a critical need to understand the disease process, and to identify improved therapeutic strategies. Previously, we...
Tue Oct 13, 2020 21:27
Transoral endoscopic thyroidectomy vestibular approach vs conventional open thyroidectomy: Meta-analysis. Head Neck. 2020 Oct 12;: Authors: Wang Y, Zhou S, Liu X, Rui S, Li Z, Zhu J, Wei T Abstract BACKGROUND: To conduct a meta-analysis to compare the safety and efficacy of transoral endoscopic thyroidectomy vestibular approach (TOETVA) with conventional open thyroidectomy (COT). METHODS: MEDLINE, EMBASE, Science Citation Index...
Tue Oct 13, 2020 21:27
Risk factors for carcinoma ex pleomorphic adenoma in patients presenting with recurrence after resection of pleomorphic adenoma. Head Neck. 2020 Oct 12;: Authors: Yin LX, Van Abel KM, Rooker SA, Nagelschneider AA, Olsen KD, Price DL, Janus JR, Kasperbauer JL, Moore EJ Abstract BACKGROUND: In patients presenting with recurrent pleomorphic adenoma (rPA), clinical evaluation can fail to recognize carcinoma ex PA (cxPA). We aim to identify...
Tue Oct 13, 2020 21:27
Bipedicled submental musculofascial "hammock" flap for salvage laryngectomy closure reinforcement. Head Neck. 2020 Oct 12;: Authors: Hayden RE, Chang BA, Mullin DP, Patel AK, Nagel TH, Howard BE, Hinni ML, Lott DL, Donald CB Abstract BACKGROUND: The aim of the study was to describe a novel technique for reinforcement of salvage laryngectomy closure using a bipedicled musculofascial submental flap. METHODS: A retrospective cohort...
Tue Oct 13, 2020 21:27
Sarcopenia as an early complication of patients with head and neck cancer with dysphagia. Eur J Cancer Care (Engl). 2020 Oct 12;:e13343 Authors: Silva PB, Ramos GHA, Petterle RR, Borba VZC Abstract OBJECTIVE: To evaluate the relationship between dysphagia and sarcopenia in patients with head and neck cancer (HNC). METHODS: A cross-sectional, prospective study, sample by convenience, including men with HNC during their initial...
Tue Oct 13, 2020 21:27
Perforator-based propeller flaps for reconstruction of massive anterolateral thigh donor site wounds. Head Neck. 2020 Oct 12;: Authors: Hudson CS, Huang AT Abstract BACKGROUND: Wide anterolateral thigh (ALT) flap donor site defects may make primary closure difficult or impossible, with split thickness skin grafting and/or negative pressure therapy often used instead. Here, we describe a technique using propeller flaps based on varying...
Tue Oct 13, 2020 21:27
Management of large intraventricular meningiomas with minimally invasive port technique: a three-case series. Neurosurg Rev. 2020 Oct 12;: Authors: Jamshidi AO, Beer-Furlan A, Hardesty DA, Ditzel Filho LFS, Prevedello LM, Prevedello DM Abstract The use of minimally invasive transcranial ports for the resection of deep-seated lesions has been shown to be safe and effective. To date, most of the literature regarding the tubular retractors...
Tue Oct 13, 2020 21:27
Tinnitus - ringing in the ears. Singapore Med J. 2020 Sep;61(9):448-452 Authors: Chan HBY, Low D, Yuen HW, How CH PMID: 33043372 [PubMed - in process]
Tue Oct 13, 2020 21:27
[Comparison of the stress distribution of microtitanium and bioresorbable plates in fixation of mandibulotomy]. Shanghai Kou Qiang Yi Xue. 2020 Jun;29(3):237-241 Authors: Han J, Xie DP, Wang HS, Zhou ZJ, Liu JN Abstract PURPOSE: The aim of this study was to compare the stress distribution of microtitanium plate and bioresorbable plates in fixation of mandibulotomy. METHODS: Three dimensional models of different internal fixation...
Tue Oct 13, 2020 21:27
Salivary gland tumors: A 15-year experience of a university hospital in Turkey. North Clin Istanb. 2020;7(4):366-371 Authors: Mengi E, Kara CO, Tumkaya F, Ardic FN, Topuz B, Bir F Abstract OBJECTIVE: To determine the demographic characteristics of benign and malignant salivary gland tumors in our department in the last 15 years. METHODS: In this study, the files of the patients who underwent salivary gland surgery between 2004 and...
Tue Oct 13, 2020 21:27
Comparison of patient stratification by computed tomography radiomics and hypoxia positron emission tomography in head-and-neck cancer radiotherapy. Phys Imaging Radiat Oncol. 2020 Jul;15:52-59 Authors: Socarrás Fernández JA, Mönnich D, Leibfarth S, Welz S, Zwanenburg A, Leger S, Löck S, Pfannenberg C, La Fougère C, Reischl G, Baumann M, Zips D, Thorwarth D Abstract Background and purpose: Hypoxia Positron-Emission-Tomography (PET) as well...
Tue Oct 13, 2020 21:27
A convolutional neural network for contouring metastatic lymph nodes on diffusion-weighted magnetic resonance images for assessment of radiotherapy response. Phys Imaging Radiat Oncol. 2020 Jul;15:1-7 Authors: Gurney-Champion OJ, Kieselmann JP, Wong KH, Ng-Cheng-Hin B, Harrington K, Oelfke U Abstract Background and purpose: Retrieving quantitative parameters from magnetic resonance imaging (MRI), e.g. for early assessment of radiotherapy treatment...
Tue Oct 13, 2020 21:27
Adjuvant treatment for high-risk salivary gland malignancies and prognostic stratification based on a 20-year single institution experience. Health Sci Rep. 2020 Dec;3(4):e195 Authors: Onderdonk BE, Vokes EE, Gwede M, Blair E, Agrawal N, Haraf DJ Abstract Background and Aim: Retrospective analysis of the utility of adjuvant radiation (RT) or chemoradiation (CRT) and identify prognostic features for patients with high-risk head and neck salivary...
Tue Oct 13, 2020 21:27
Evaluation of Vision in Gnathological and Orthodontic Patients with Temporomandibular Disorders: A Prospective Experimental Observational Cohort Study. J Int Soc Prev Community Dent. 2020 Jul-Aug;10(4):481-490 Authors: Vompi C, Serritella E, Galluccio G, Pistella S, Segnalini A, Giannelli L, Di Paolo C Abstract Objectives: Temporomandibular disorders (TMDs), orthodontic diseases, and vision dysfunctions seem to be strictly related. The purpose...
Tue Oct 13, 2020 21:27
HPV Detection in Head and Neck Squamous Cell Carcinomas: What Is the Issue? Front Oncol. 2020;10:1751 Authors: Augustin JG, Lepine C, Morini A, Brunet A, Veyer D, Brochard C, Mirghani H, Péré H, Badoual C Abstract Besides classic tobacco and alcohol risk factors, human papillomavirus (HPV) plays a role in the development of a subset of head and neck squamous cell carcinomas (HNSCCs), and notably oropharynx squamous cell carcinomas (OPSCCs)....
Tue Oct 13, 2020 21:27
Immunological Network in Head and Neck Squamous Cell Carcinoma-A Prognostic Tool Beyond HPV Status. Front Oncol. 2020;10:1701 Authors: Fialová A, Koucký V, Hajdušková M, Hladíková K, Špíšek R Abstract Head and neck squamous cell carcinoma (HNSCC) is a highly heterogeneous disease that affects more than 800,000 patients worldwide each year. The variability of HNSCC is associated with differences in the carcinogenesis processes that are caused...
Tue Oct 13, 2020 21:27
Clinical Trials for Artificial Intelligence in Cancer Diagnosis: A Cross-Sectional Study of Registered Trials in ClinicalTrials.gov. Front Oncol. 2020;10:1629 Authors: Dong J, Geng Y, Lu D, Li B, Tian L, Lin D, Zhang Y Abstract Objective: Clinical trials are the most effective way to judge the merits of diagnosis and treatment strategies. The in-depth mining of clinical trial data enables us to grasp the application trend of artificial intelligence...
Tue Oct 13, 2020 21:27
Acute Stroke in a Young Patient With Coronavirus Disease 2019 in the Presence of Patent Foramen Ovale. Cureus. 2020 Sep 03;12(9):e10233 Authors: Ashraf M, Sajed S Abstract We present an interesting case of acute ischemic stroke in a 26-year-old patient with coronavirus disease 2019, who presented to the hospital initially with headache, vomiting, and right-sided numbness and tingling. The initial workup was negative, including computed tomography...
Tue Oct 13, 2020 21:27
Intraoperative Neurophysiological Monitoring During Trigeminal Schwannoma Surgery. Cureus. 2020 Sep 03;12(9):e10218 Authors: Jahangiri FR, Azam A, Asdi RA, Ahmad I, Basha SI Abstract Surgical manipulation during skull base surgeries places various cranial nerves (CN) at risk, including the nerves innervating the extraocular muscles. It could be very challenging for the surgeon to identify these cranial nerves due to the distortion of the normal...
Tue Oct 13, 2020 21:27
CD38 triggers inflammasome-mediated pyroptotic cell death in head and neck squamous cell carcinoma. Am J Cancer Res. 2020;10(9):2895-2908 Authors: Zhang MJ, Gao W, Liu S, Siu SP, Yin M, Ng JC, Chow VL, Chan JY, Wong TS Abstract BACKGROUND: Pyroptosis is a form of inflammatory cell death. Although it is recognized that NLRP3 (nucleotide-binding domain, leucine-rich repeat-containing family, pyrin domain-containing 3) inflammasome is involved...
Tue Oct 13, 2020 21:27
Mechanisms of resistance in head and neck cancer. Am J Cancer Res. 2020;10(9):2742-2751 Authors: Picon H, Guddati AK Abstract Resistance to treatment is one of the biggest challenges in combating head and neck squamous cell carcinoma (HNSCC). The concept of resistance, however, is often viewed as a whole without categorization into the two types of resistance: acquired and intrinsic. Comparison of the mechanisms of the two types of resistance...
Tue Oct 13, 2020 21:27
Analysis of the critical dose of radiation therapy in the incidence of Osteoradionecrosis in head and neck cancer patients: a case series. BDJ Open. 2020;6:18 Authors: Iqbal Z, Kyzas P Abstract Introduction: Osteoradionecrosis (ORN) is a dramatic complication following radiation therapy (RT) for head and neck tumours. Symptoms include pain, trismus, and malodour. ORN can present with exposed necrotic bone, an orocutaneous fistula, and/ or...
Tue Oct 13, 2020 21:27
Current transition management of adolescents and young adults with allergy and asthma: a European survey. Clin Transl Allergy. 2020;10:40 Authors: Khaleva E, Vazquez-Ortiz M, Comberiati P, DunnGalvin A, Pite H, Blumchen K, Garriga-Baraut T, Hox V, Santos AF, Gore C, Knibb RC, Alviani C, Mortz CG, Angier E, Duca B, Jensen B, Sanchez-Garcia S, Gowland MH, Timmermans F, Pfaar O, Roberts G Abstract Background: Transition from parent-delivered...
Tue Oct 13, 2020 21:27
KIT gene mutation causes deafness and hypopigmentation in Bama miniature pigs. Am J Transl Res. 2020;12(9):5095-5107 Authors: Xu C, Ren W, Zhang Y, Zheng F, Zhao H, Shang H, Guo W, Yang S Abstract Waardenburg syndrome (WS) is a common syndromic hearing loss disease. A large group of patients affected by WS were found no mutations in the existed gene panel, indicating that there are still potential genes responsible for WS yet to be detected....
Tue Oct 13, 2020 21:27
Immunopathological features of air pollution and its impact on inflammatory airway diseases (IAD). World Allergy Organ J. 2020 Oct;13(10):100467 Authors: Rouadi PW, Idriss SA, Naclerio RM, Peden DB, Ansotegui IJ, Canonica GW, Gonzalez-Diaz SN, Rosario Filho NA, Ivancevich JC, Hellings PW, Murrieta-Aguttes M, Zaitoun FH, Irani C, Karam MR, Bousquet J Abstract Air pollution causes significant morbidity and mortality in patients with inflammatory...
Tue Oct 13, 2020 21:27
A New Form of Irritant Rhinitis to Filtering Face-Piece Particle (FFP) Masks (FFP2/N95/KN95 Respirators) during COVID-19 Pandemic. World Allergy Organ J. 2020 Oct 06;:100474 Authors: Klimek L, Huppertz T, Alali A, Spielhaupter M, Hörmann K, Matthias C, Hagemann J Abstract Filtering facepiece particle (FFP) masks are important items of personal protective equipment in fighting COVID-19 pandemic. They shall protect the wearer of the mask from...
Tue Oct 13, 2020 21:27
Intracranial Rhabdomyosarcoma of the Cerebellopontine Angle in a 6-year-old Child: A Case Report. J Pediatr Neurosci. 2020 Apr-Jun;15(2):124-127 Authors: Masoudi MS, Zafarshamspour S, Ghasemi-Rad M, Soleimani N, Lincoln C Abstract Rhabdomyosarcoma (RMS) is the most common soft-tissue malignancy in children under 15 years of age. Approximately, 35% of RMS cases originate from the head and neck region. Among various sites in the head and neck...
Tue Oct 13, 2020 21:27
Perilymphatic Fistula: A Review of Classification, Etiology, Diagnosis, and Treatment. Front Neurol. 2020;11:1046 Authors: Sarna B, Abouzari M, Merna C, Jamshidi S, Saber T, Djalilian HR Abstract A perilymphatic fistula (PLF) is an abnormal communication between the perilymph-filled inner ear and the middle ear cavity, mastoid, or intracranial cavity. A PLF most commonly forms when the integrity of the oval or round window is compromised,...
Tue Oct 13, 2020 21:27
Stress and Tinnitus; Transcutaneous Auricular Vagal Nerve Stimulation Attenuates Tinnitus-Triggered Stress Reaction. Front Psychol. 2020;11:570196 Authors: Ylikoski J, Markkanen M, Pirvola U, Lehtimäki JA, Ylikoski M, Jing Z, Sinkkonen ST, Mäkitie A Abstract Introduction: Tinnitus can become a strong stressor for some individuals, leading to imbalance of the autonomous nervous system with reduction of parasympathetic activity. It can manifest...
Tue Oct 13, 2020 21:27
Propeller Flaps in the Head and Neck. Semin Plast Surg. 2020 Aug;34(3):165-170 Authors: Cordova A, D'Arpa S, Rosatti F, Nichelini M, D'Antonio GM, Giordano S, Toia F Abstract Propeller flaps have significantly expanded the reconstruction possibilities in the head and neck region. They allow for increased flap mobility and better scar concealing, and/or to perform a one-stage reconstruction with local tissue of similar color and texture,...
Tue Oct 13, 2020 21:27
Pleomorphic adenoma of the nasal septum - A rare entity. Natl J Maxillofac Surg. 2020 Jan-Jun;11(1):136-139 Authors: Bose S, Agarwal M, Nawale K Abstract Pleomorphic adenoma (PA) is the most common benign tumor of major salivary glands, and it rarely arises in minor salivary glands. PA has been reported at various sites where minor salivary glands are found and include nasal cavity, nasopharynx, pharynx, larynx, hypopharynx, and even lacrimal...
Tue Oct 13, 2020 21:27
Frontoethmoidal mucocele causing proptosis and visual loss. Natl J Maxillofac Surg. 2020 Jan-Jun;11(1):121-123 Authors: Dey S, Agarwal M Abstract Mucoceles are benign mucus-containing cysts formed due to the obliteration of sinus ostium. They are most commonly found in the frontal sinus. Mucoceles can spread both intraorbitally and intracranially causing complications such as meningitis, brain abscess, and loss of vision. Radiological investigations...
Tue Oct 13, 2020 21:27
Temporal Bone Chondroblastoma: a Rare Entity. Med Arch. 2020 Aug;74(4):312-314 Authors: Yusof ANM, Thong HK, Kamalden TMIT Abstract Introduction: Chondroblastoma is an uncommon benign, locally destructive tumor that usually arises from epiphyses of the long bones. Temporal bone chondroblastoma is an extremely rare occurrence. Chondroblastoma arise from immature cartilage cells and it may display certain malignant features by invading surrounding...
Tue Oct 13, 2020 21:27
Irradiation therapy and chewing simulation: effect on zirconia and human enamel. J Prosthodont Res. 2020 Oct 09;: Authors: Hajhamid B, De Souza GM Abstract PURPOSE: Ionizing radiation therapy (RT) is the main option for head and neck cancer treatment, but it is associated with multiple side effects. This study aimed to evaluate the effect of RT associated with chewing simulation on the surface of human enamel and Yttria-partially stabilized...
Tue Oct 13, 2020 21:27
Chronic rhinosinusitis and progression of cognitive impairment in dementia. Eur Ann Otorhinolaryngol Head Neck Dis. 2020 Oct 08;: Authors: Jung HJ, Lee JY, Choi YS, Choi HG, Wee JH Abstract AIM: The relationship between chronic inflammatory disease and cognitive decline is still unclear, but there is increasing evidence to support the role of systemic inflammation. The aim of this study was to investigate if chronic rhinosinusitis (CRS)...
Tue Oct 13, 2020 21:27
Functional outcomes and tracheostomy dependence following salvage oropharyngeal surgery. Oral Oncol. 2020 Oct 08;:105034 Authors: Heft Neal ME, Gao RW, Brennan JR, Haring CT, Chinn SB, Shuman AG, Casper KA, Malloy KM, Stucken CL, Mclean SA, Chad Brenner J, Lyden T, Blakely A, Mierzwa ML, Shah J, Schonewolf C, Swiecicki PL, Worden FP, Wolf GT, Bradford CR, Prince MEP, Rosko AJ, Spector ME PMID: 33041214 [PubMed - as supplied by publisher]
Tue Oct 13, 2020 21:27
Using 3D-printed nose models in nasopharyngeal swab training. Oral Oncol. 2020 Oct 08;:105033 Authors: Chee J, Lin X, Lim WS, Loh WS, Thong M, Ng L Abstract BACKGROUND: The COVID-19 pandemic has swept across the globe with massive effects on health care systems as well as global economies. Enhanced testing has been put forward as a means to reduce transmission while awaiting the development of targeted therapy or effective vaccination....
Tue Oct 13, 2020 21:27
Insulin-like growth factor 1 promotes the extension of Tracheal Epithelium in an in Vitro Tracheal organ culture model. Auris Nasus Larynx. 2020 Oct 08;: Authors: Kishimoto I, Ohnishi H, Yamahara K, Nakagawa T, Yamashita M, Omori K, Yamamoto N Abstract OBJECTIVE: Rapid epithelialization is crucial to maintain tracheal patency and prevent potential graft failure in tracheal reconstruction after tracheal resection for cancer with tracheal...
Tue Oct 13, 2020 21:27
Magnetic Resonance Safety. Magn Reson Imaging Clin N Am. 2020 Nov;28(4):xiii Authors: Mukherji SK PMID: 33041000 [PubMed - in process]
Tue Oct 13, 2020 21:27
Molecular Imaging in the Head and Neck: Diagnosis and Therapy. Radiol Clin North Am. 2020 Nov;58(6):1135-1146 Authors: Howard BA Abstract This article is a summary of the most up-to-date applications of radiopharmaceuticals to the diagnosis and therapy of benign and malignant diseases involving endocrine or neuroendocrine organs of the head and neck, focusing on radiotracers approved by the US Food and Drug Administration, such as I-123-...
Tue Oct 13, 2020 21:27
Effects of oral desloratadine citrate disodium combined with physiological seawater nasal irrigation on IgE levels, IL-4, IL-6, IL-13 and IFN-γ expression and treatment of intermittent allergic rhinitis. Cell Mol Biol (Noisy-le-grand). 2020 Jul 31;66(5):54-58 Authors: Zhang Y, Li W Abstract This experiment was performed to explore the effect of oral desloratadine citrate disodium combined with physiological seawater nasal irrigation in...
Tue Oct 13, 2020 21:27
[Progress in evaluation of swallowing function after treatment of head and neck malignant tumors]. Lin Chung Er Bi Yan Hou Tou Jing Wai Ke Za Zhi. 2020 Sep;34(9):861-864 Authors: Ren J, Lv D, Liu S Abstract After treatment, patients with head and neckmalignant tumors may suffer from dysphagia, which may lead to aspiration pneumonia, cough and other complications, even threaten life, seriously affecting patients'quality of life. Through...
Tue Oct 13, 2020 21:27
[Clinical and genetic characteristics of 131 cases of congenital preauricular fistula]. Lin Chung Er Bi Yan Hou Tou Jing Wai Ke Za Zhi. 2020 Sep;34(9):840-843 Authors: Chen J, Zhou P, Huang T, Tao Z Abstract Objective:To investigate the clinical and genetic characteristics of congenital preauricular fistula. Method:The clinical data of 131 patients（143 ears） with congenital preauricular fistula. The patient's age distribution, sex ratio,...
Tue Oct 13, 2020 21:27
[Balloon Eustachian tuboplasty for treatment of Eustachian tube dysfunction: A systematic review and Meta-analysis]. Lin Chung Er Bi Yan Hou Tou Jing Wai Ke Za Zhi. 2020 Sep;34(9):828-835 Authors: Zhang Y, Li W, Ma X, Wang W, Zhao J, Jia Z, Zhang J, Wang Y Abstract Objective:To sysetematically evaluate the efficacy, compliance and collaborative operation of Balloon Eustachian tuboplasty（BET） for treatment of Eustachian tube dysfunction...
Tue Oct 13, 2020 21:27
[Endoscope-assisted transoral resection of parapharyngeal space tumors: a retrospective study]. Lin Chung Er Bi Yan Hou Tou Jing Wai Ke Za Zhi. 2020 Sep;34(9):824-827;835 Authors: He L, Xie J, Gao X Abstract Objective:To evaluate the feasibility and safety of the endoscope-assisted transoral approach for the parapharyngeal space（PPS） tumors. Method:This retrospective study included 22 patients who were diagnosed with PPS tumors and treated...
Tue Oct 13, 2020 21:27
[Clinical characteristics analysis of patients with Meniere's disease and vestibular migraine]. Lin Chung Er Bi Yan Hou Tou Jing Wai Ke Za Zhi. 2020 Sep;34(9):820-823 Authors: Chen Y, Sun H, Zhang Q, Qu Y, Li J, Zhou L, Yang M, Lu H, Zhao L, Sun Q Abstract Objective:To analyze the clinical characteristics of patients with Meniere's disease and vestibular migraine, improve the understanding of such diseases for accurate treatment. Method:Eighteen...
Tue Oct 13, 2020 21:27
[Clinical value of upper airway MSCT measurement in adult male patients with moderate to severe OSA]. Lin Chung Er Bi Yan Hou Tou Jing Wai Ke Za Zhi. 2020 Sep;34(9):814-819 Authors: Guo C, Long P, Ye J, Li H Abstract Objective:To investigate the pathogenesis of OSA-related through 128-slice spiral CT measurements of adult male patients with moderate to severe OSA at different respiratory phases, and to optimize treatment options for patients...
Tue Oct 13, 2020 21:27
[A modified STOP-Bang questionnaire for OSA screening in the young, middle-age women]. Lin Chung Er Bi Yan Hou Tou Jing Wai Ke Za Zhi. 2020 Sep;34(9):811-814 Authors: Chen X, Zhang R, Jia J, Yuan W, Li J Abstract Objective:The STOP-Bang（S-B） questionnaire is widely used for screening patients with OSA. However, BMI and NC cutoff value in the original S-B questionnaire is 35 kg/m²and 40cm, the BMI and NC value in the young and middle-aged...
Tue Oct 13, 2020 21:27
[Microbiology of chronic rhinosinusitis with different clinical phenotypes]. Lin Chung Er Bi Yan Hou Tou Jing Wai Ke Za Zhi. 2020 Sep;34(9):805-810 Authors: Liu X, Liu H, Li C, Wu W Abstract Objective:To observe the microbiological characteristics and clinical correlation of chronic rhinosinusitis with different clinical phenotypes. Method:One hundred and ninety-six patients with chronic rhinosinusitis（CRS） underwent nasal endoscopic surgery,...
Tue Oct 13, 2020 21:27
[The correlation between nasal bacterial microbiome diversity and surgical prognosis for chronic sinusitis with nasal polyp]. Lin Chung Er Bi Yan Hou Tou Jing Wai Ke Za Zhi. 2020 Sep;34(9):799-804 Authors: Yang F, Gan W, Liu F, Xian J, Liu S, Meng J Abstract Objective:To compare the nasal microbiota diversity between chronic rhinosinusitis with nasal polyp（CRSwNP） patients and controls, postoperative recurrent with non-recurrent CRSwNP,...
Tue Oct 13, 2020 21:27
[Identification of a novel mutation of CEACAM16 gene in a Chinese family with autosomal dominant nonsyndromic hearing loss]. Lin Chung Er Bi Yan Hou Tou Jing Wai Ke Za Zhi. 2020 Sep;34(9):777-781 Authors: Zhang Q, Wu K, Zhao C, Xie L, Xiong F, Lan L, Wang Q Abstract Objective:To explore the genetic cause of a Chinese autosomal dominant nonsyndromic hearing loss family and investigate the clinical features and molecular genetic characteristics...
Tue Oct 13, 2020 21:27
[Guidance of laser therapy for early laryngeal carcinoma by mucosal wave changes]. Lin Chung Er Bi Yan Hou Tou Jing Wai Ke Za Zhi. 2020 Sep;34(9):769-772 Authors: Ding S, Huang J, Guo W, Zhang Y, Zhong Q, Huang Z Abstract Objective:Analyze the relationship between the change of mucosal wave and the infiltrating level of early laryngeal carcinoma so as to guide the cordectomy. Method:Retrospective research on patients of 1a stage without...
Tue Oct 13, 2020 21:27
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