Head and Neck Medicine by Alexandros G.Sfakianakis

Distribution of residual disease in the peritoneum following neoadjuvant chemotherapy in advanced epithelial ovarian cancer and its potential therapeutic implications

Publication date: Available online 14 October 2020Source: European Journal of Surgical OncologyAuthor(s): Aditi Bhatt, Naoual Bakrin, Praveen Kammar, Sanket Mehta, Snita Sinukumar, Loma Parikh, Sakina Shaikh Bhms, Suniti Mishra, Mrinal Mallaya, Vahan Kepenkian, Nazim Benzerdjeb, Olivier Glehen

Managing NON-DIAGNOSTIC biopsies in musculoskeletal tumours in a specialist centre: Deciding on the algorithm

Wed Oct 14, 2020 21:27

Publication date: Available online 14 October 2020Source: European Journal of Surgical OncologyAuthor(s): George S. Tamvakopoulos, Barry Rose, Asif Saifuddin, John A. Skinner, Robin Pollock

Long term survival in patients with peritoneal metastasised gastric cancer treated with cytoreductive surgery and HIPEC: A multi-institutional cohort from PSOGI

Wed Oct 14, 2020 21:27

Publication date: Available online 14 October 2020Source: European Journal of Surgical OncologyAuthor(s): Andreas Brandl, Yutaka Yonemura, Olivier Glehen, Paul Sugarbaker, Beate Rau

Increased ultrasonographic endometrial thickness is associated with poor survival in patients with endometrial cancer: An Israel gynecologic oncology group study

Wed Oct 14, 2020 21:27

Publication date: Available online 14 October 2020Source: European Journal of Surgical OncologyAuthor(s): Ahmet Namazov, Ofer Gemer, Nasreen Hag-Yahia, Ram Eitan, Oded Raban, Zvi Vaknin, Sophia Leytes, Ofer Lavie, Alon Ben-Arie, Amnon Amit, Tally Levy, Michael Volodarsky, Inbar Ben Shachar, Ilan Atlas, Ilan Bruchim, Limor Helpman

Prognosis impact of posttreatment pelvic MRI in patients treated for stage IB2-IIB cervical cancer with chemoradiation therapy

Wed Oct 14, 2020 21:27

Publication date: Available online 13 October 2020Source: European Journal of Surgical OncologyAuthor(s): Tiphaine Moussilmani, Sophie Knight, Julien Mancini, Cyril Touboul, Florence Rodriguez, Pierre Adrien Bolze, Sofiane Bendifallah, Marcos Ballester, Pierre Collinet, Yohan Kerbage, Lobna Ouldamer, Geoffroy Atrous, Vincent Lavoué, Ludivine Dion, Yohann Dabi, Emilie Raimond, Olivier Graesslin, Cyrille Huchon, Myriam Mimouni, Alexandre Bricou

Breast cancer in the oldest old (≥ 89 years): Tumor characteristics, treatment choices, clinical outcomes and literature review

Wed Oct 14, 2020 21:27

Publication date: Available online 13 October 2020Source: European Journal of Surgical OncologyAuthor(s): Simona Di Lascio, Enrico Tognazzo, Sara Bigiotti, Marta Bonollo, Alberto Costa, Olivia Pagani, Francesco Meani

Absence of residual fluorescence in the surgical bed at near-infrared fluorescence imaging predicts negative margins at final pathology in patients treated with breast-conserving surgery for breast cancer

Wed Oct 14, 2020 21:27

Publication date: Available online 13 October 2020Source: European Journal of Surgical OncologyAuthor(s): Florin-Catalin Pop, Isabelle Veys, Sophie Vankerckhove, Romain Barbieux, Marie Chintinne, Michel Moreau, Vincent Donckier, Denis Larsimont, Pierre Bourgeois, Gabriel Liberale

Robot-assisted surgery for women with endometrial cancer: Surgical and oncologic outcomes within a Belgium gynaecological oncology group cohort

Tue Oct 13, 2020 17:43

Publication date: Available online 13 October 2020Source: European Journal of Surgical OncologyAuthor(s): A. Kakkos, C. Ver Eecke, S. Ongaro, K. Traen, F. Peeters, Ph Van Trappen, A. Laenen, E. Despierre, E. Van Nieuwenhuysen, I. Vergote, F. Goffin

Electrochemotherapy and Simultaneous Photodynamic Bone Stabilization of Upper Limbs in Metastatic Renal Cancer Disease: Case Report and Literature Review

Tue Oct 13, 2020 17:43

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Case Reports in Medicine

Introduction. Metastatic bone disease represents a systemic pathology that heavily affects the quality of life of oncologic patients causing pain and functional disability. Methodology. We present the case of a patient with a history of renal cell cancer presenting pathologic fractures of both humeri and proximal right radius. Results. After a careful multidisciplinary approach, an adjuvant anticancer therapy and a photodynamic bone stabilization procedure were performed with a minimally invasive...

Case Reports in Medicine

Wed Oct 14, 2020 08:20

Finding the Cause of Psychosis: A Challenging Case of Anti-NMDAR Encephalitis

An autoimmune response causing inflammation in the brain tissue is called autoimmune encephalitis. Autoantibodies directed against N-methyl-D-aspartate (NMDA) receptors cause a type of autoimmune encephalitis resulting in memory loss, confusion, and psychosis. A 28-year-old male with a history of schizophrenia, seizure disorder, and stroke presented with a 2-day history of bizarre behavior, restlessness, insomnia, agitation, and hallucinations. He was initially managed for acute psychosis without...

Case Reports in Medicine

Tue Oct 13, 2020 12:35

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Silibinin ameliorats H2O2-induced cell apoptosis and oxidative stress response by activating Nrf2 signaling in trophoblast cells

Publication date: December 2020Source: Acta Histochemica, Volume 122, Issue 8Author(s): Hui Guo, Ying Wang, Di Liu

Comparison of similar cells: Mesenchymal stromal cells and fibroblasts

Wed Oct 14, 2020 20:39

Publication date: December 2020Source: Acta Histochemica, Volume 122, Issue 8Author(s): Burcu Ugurlu, Erdal Karaoz

Tue Oct 13, 2020 16:59

Editorial Board

Publication date: October 2020Source: Acta Histochemica, Volume 122, Issue 7Author(s):

Tue Oct 13, 2020 16:59

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Pro resolving inflammatory effects of the lipid mediators of omega 3 fatty acids and its implication in SARS COVID-19

Publication date: December 2020Source: Medical Hypotheses, Volume 145Author(s): Pedro-Antonio Regidor, Fernando Gonzalez Santos, Jose Miguel Rizo, Fernando Moreno Egea

NCAM protein and SARS-COV-2 surface proteins: In-silico hypothetical evidence for the immunopathogenesis of Guillain-Barré syndrome

Wed Oct 14, 2020 20:06

Publication date: December 2020Source: Medical Hypotheses, Volume 145Author(s): Sara Morsy

Viral replication of SARS-CoV-2 could be self-limitative – The role of the renin-angiotensin system on COVID-19 pathophysiology

Wed Oct 14, 2020 20:06

Publication date: December 2020Source: Medical Hypotheses, Volume 145Author(s): Vinicius Novaes Rocha

Is a COVID-19 vaccine developed by nature already at work?

Tue Oct 13, 2020 13:50

Publication date: December 2020Source: Medical Hypotheses, Volume 145Author(s): Nilesh Kumar Sharma, Sachin C. Sarode, Gargi Sarode, Shankargouda Patil

Tue Oct 13, 2020 13:50

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Work participation and physicality of work in young adulthood and the development of unhealthy lifestyle habits and obesity later in life: a prospective cohort study

ObjectiveTo determine the effects of early entry into the labour market and physicality of work in young adulthood on the development of obesity and unhealthy lifestyle habits later in life.MethodsThis study is a part of the Young Finns Study. Entry into the labour market and physicality of work were measured at baseline, when participants were aged 18, 21, or 24 years in 1986 or 18 years in 1989. Follow-up of lifestyle habits were conducted in 2001, 2007 and 2011. The outcomes were obesity (n=5558...

Employment and earnings trajectories before and after sickness absence due to major depressive disorder: a nationwide case-control study

Wed Oct 14, 2020 19:00

ObjectivesTo examine employment and earnings trajectories before and after the first sickness absence period due to major depressive disorder (MDD).MethodsAll individuals (n=158 813) in Finland who had a first sickness absence period (lasting longer than 9 days) due to MDD between 2005 and 2015 were matched with one randomly selected individual of the same age and gender with no history of MDD. Employment status and earnings were measured using register-based data annually from 2005 to 2015. Generalised...

Extreme diurnal temperature range and cardiovascular emergency hospitalisations in a Mediterranean region

Tue Oct 13, 2020 19:00

ObjectivesThe impact of extreme diurnal temperature range (DTR) on cardiovascular morbidity in Mediterranean regions remains uncertain. We aimed to analyse the impact of extreme low DTR (stable temperature) or high DTR (changeable temperature) on cardiovascular hospitalisations in Catalonia (Southern Europe).MethodsWe conducted a self-controlled case series study using whole-year data from the System for the Development of Research in Primary Care database and 153 weather stations from the Catalan...

Journal of Endocrinological Investigation

Tue Oct 13, 2020 19:00

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TSH lowering effects of metformin: a possible mechanism of action

Abstract Preliminary clinical evidence suggests that metformin has TSH lowering effects in patients with T2DM and hypothyroidism or in those with TSH serum levels in the upper normal value. Also, metformin may exert a protective role against thyroid nodules growth in patients without insulin-resistance. The cross-talk between tyrosine kinase receptors and the G protein-coupled receptors (which the TSHR belongs to) has been already shown and IRS1 may represent the hub link between...

Journal of Endocrinological Investigation

Wed Oct 14, 2020 03:00

Decreased Sestrin levels in patients with type 2 diabetes and dyslipidemia and their association with the severity of atherogenic index

Abstract Purpose We earlier reported that Sestrin2 regulates monocyte activation and atherogenic events through AMPK-mTOR nexus under high-glucose and dyslipidemic conditions. However, the statuses of Sestrins in diabetes and dyslipidemia are not known. We report here on the status of Sestrins and their association with diabetic dyslipidemia and atherosclerosis. Methods...

Journal of Endocrinological Investigation

Tue Oct 13, 2020 03:00

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Clinical & Experimental Allergy

Staphylococcus aureus enterotoxin B disrupts nasal epithelial barrier integrity

Abstract Background Staphylococcus aureus colonization and release of enterotoxin B (SEB) has been associated with severe chronic rhinosinusitis with nasal polyps (CRSwNP). The pathogenic mechanism of SEB on epithelial barriers, however, is largely unexplored. Objective We investigated the effect of SEB on nasal epithelial barrier function. Methods SEB was apically administered to air‐liquid interface (ALI) cultures of primary polyp and nasal epithelial cells of CRSwNP patients and...

Clinical & Experimental Allergy

Wed Oct 14, 2020 18:08

Reply to “Efficacy and safety of hydrolyzed formulas for cow’s milk allergy management: A systematic review of randomized controlled trials”

Abstract We read with interest the systematic review “Efficacy and safety of hydrolyzed formulas for cow’s milk allergy management: A systematic review of randomized controlled trials” performed by Stróżyk et al. [1]. Being strong supporters of Open Science, we were pleased to provide, under the request of Dr. Stróżyk, the complete datasets of two published randomized controlled trials (RCTs) performed by our group [2,3]. We found some inaccuracies, including calculation errors, in the new analysis...

Clinical & Experimental Allergy

Mon Oct 12, 2020 17:38

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Dysphagia

Sensitivity and Specificity of Bedside Screening Tests for Detection of Aspiration in Patients Admitted to a Public Rehabilitation Hospital

Abstract Early detection of dysphagia and specifically aspiration is essential to prevent and reduce complications of hospitalized patients in rehabilitation centers. Bedside screening test are often used to evaluate swallowing disorders, but their results may be questionable due to insufficient and inconsistent sensitivity and specificity. To compare the sensitivity and specificity of various bedside screening tests for detecting aspiration in hospitalized rehabilitation patients....

Dysphagia

Wed Oct 14, 2020 03:00

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Rapid Evolution and Rupture of an Incidental Aneurysm During Hyperdynamic Therapy for Cerebral Vasospasm

Publication date: January 2021Source: World Neurosurgery, Volume 145Author(s): Gustavo Chagoya, Arsalaan Salehani, B. Ethan Tabibian, Nicholas M.B. Laskay, Brandon M. Fox, Nidal B. Omar, Bart Thaci, Joshua D. Bernstock, Galal A. Elsayed, Mark R. Harrigan

Spontaneous Regression of Radiologically Diagnosed Epidermoid Cyst Originating from the Cerebellopontine Angle

Wed Oct 14, 2020 19:52

Publication date: December 2020Source: World Neurosurgery, Volume 144Author(s): Tomoki Kaneko, Yasunari Fujinaga, Fumihito Ichinohe, Toshihiro Ogiwara, Tetsuyoshi Horiuchi

Dilated Epidural Venous Plexus Causing Radiculopathy: A Report of 2 Cases and Review of the Literature

Wed Oct 14, 2020 19:52

Publication date: December 2020Source: World Neurosurgery, Volume 144Author(s): David R. Hallan, Sarah McNutt, G. Timothy Reiter, Krishnamoorthy Thamburaj, Charles S. Specht, Mark Knaub

Successful Use of Tissue Plasminogen Activator for Saddle Pulmonary Embolism in Perimesencephalic Nonaneurysmal Subarachnoid Hemorrhage

Wed Oct 14, 2020 19:52

Publication date: December 2020Source: World Neurosurgery, Volume 144Author(s): Ken Porche, Christopher Robinson, Adam Polifka

Salvage Gamma Knife Stereotactic Radiosurgery for Recurrent Intracranial Langerhans Cell Histiocytosis: A 36-Year Saga

Wed Oct 14, 2020 19:52

Publication date: December 2020Source: World Neurosurgery, Volume 144Author(s): Andrew Faramand, Ajay Niranjan, John Flickinger, Edward Monaco, L. Dade Lunsford

Perioperative Assessment of Cerebellar Masses and the Potential for Cerebellar Cognitive Affective Syndrome

Wed Oct 14, 2020 19:52

Publication date: December 2020Source: World Neurosurgery, Volume 144Author(s): Eric W. Sankey, Ethan S. Srinivasan, Vikram A. Mehta, Stephen M. Bergin, Timothy Y. Wang, Eric M. Thompson, Peter E. Fecci, Allan H. Friedman

The History of Anterior and Lateral Approaches to the Lumbar Spine

Wed Oct 14, 2020 19:52

Publication date: December 2020Source: World Neurosurgery, Volume 144Author(s): Abhijith V. Matur, Juan C. Mejia-Munne, Zachary J. Plummer, Joseph S. Cheng, Charles J. Prestigiacomo

Geospatial Distribution of Neurosurgeons Age 60 and Above Relative to the Spread of COVID-19

Wed Oct 14, 2020 19:52

Publication date: Available online 14 October 2020Source: World NeurosurgeryAuthor(s): Tarun K. Jella, Ansh Desai, Taral Jella, Michael Steinmetz, Kristopher Kimmell, James Wright, Christina Huang Wright, in affiliation with the Council of State Neurosurgical Societies (CSNS)

Surgical treatment of chronic subdural haematomas in nonagenarians: who to treat?

Wed Oct 14, 2020 19:52

Publication date: Available online 14 October 2020Source: World NeurosurgeryAuthor(s): Frederick Ewbank, Andrew Durnford, Danyal Akarca, Ahmed- Ramadan Sadek, Jonathan Hempenstall

Demonstration of Microsurgical Technique and Nuances for the Obliteration of Complex Intracranial Dural Arteriovenous Fistulas in Three Consecutive Cases: Operative Video

Wed Oct 14, 2020 19:52

Publication date: Available online 14 October 2020Source: World NeurosurgeryAuthor(s): Burcak Soylemez, Yahya Turan, Sima Sayyahmelli, Mustafa k. Başkaya

Outcomes after decompressive craniectomy for ischemic stroke: a volumetric analysis

Wed Oct 14, 2020 19:52

Publication date: Available online 14 October 2020Source: World NeurosurgeryAuthor(s): Jonathan M. Parish, Anthony M. Asher, Deborah Pfortmiller, Mark D. Smith, Jonathan D. Clemente, William R. Stetler, Joe D. Bernard

Clinical Results and Complications of Endoscopic Lumbar Interbody Fusion for Lumbar Degenerative Disease: A Meta-Analysis

Wed Oct 14, 2020 19:52

Publication date: Available online 13 October 2020Source: World NeurosurgeryAuthor(s): Dong Hwa Heo, Dong Chan Lee, Hyeun Sung Kim, Choon Keun Park., Hungtae Chung

Cerebral Microdialysis as a Tool for Assessing the Delivery of Chemotherapy in Brain Tumor Patients

Wed Oct 14, 2020 19:52

Publication date: January 2021Source: World Neurosurgery, Volume 145Author(s): Charles F. Pierce, Amanda Kwasnicki, Sajani S. Lakka, Herbert H. Engelhard

Diversity in Neurosurgery

Tue Oct 13, 2020 18:43

Publication date: January 2021Source: World Neurosurgery, Volume 145Author(s): Eliana E. Kim, Andrea L. Klein, Jean W. Lartigue, Shawn L. Hervey-Jumper, Gail Rosseau

Tue Oct 13, 2020 18:43

A Case of Cervical Radiculopathy Presenting as Dystonic Tremor

Publication date: December 2020Source: World Neurosurgery, Volume 144Author(s): Samuel K. Freeman, Angus Nisbet, Rafid Al-Mahfoudh

Endoscopic Extracapsular Resection of an Adrenocorticotropic Hormone–Secreting Macroadenoma with Selective Resection of the Medial Cavernous Sinus Wall

Tue Oct 13, 2020 18:43

Publication date: December 2020Source: World Neurosurgery, Volume 144Author(s): Hamid Borghei-Razavi, Baha'eddin A. Muhsen, Krishna Joshi, Troy Woodard, Varun R. Kshettry

Intraoperative Thrombolysis of Massive Pulmonary Embolus During Spine Surgery: Case Report of Survival Complicated by Massive Bleeding and Review of the Literature

Tue Oct 13, 2020 18:43

Publication date: Available online 13 October 2020Source: World NeurosurgeryAuthor(s): Ryan Holland, John K. Houten, Shahenaz Elsamragy, Jinu Kim, Galina Leyvi, Merritt D. Kinon

Early Effects of COVID-19 Pandemic on Neurosurgical Training in the United States: A Case Volume Analysis of Eight Programs

Tue Oct 13, 2020 18:43

Publication date: Available online 13 October 2020Source: World NeurosurgeryAuthor(s): Zaid S. Aljuboori, Christopher C. Young, Visish M. Srinivasan, Ryan T. Kellogg, Jennifer L. Quon, Mohammed A. Alshareef, Stephanie H. Chen, Michael Ivan, Gerald A. Grant, Sean D. McEvoy, Justin R. Davanzo, Sonia Majid, Sharon Durfy, Michael R. Levitt, Emily P. Sieg, Richard G. Ellenbogen, Haring J. Nauta

Effect of abdominal aortic balloon occlusion timing on femoral nerve injury in patients with dangerous placenta preview based on color dropper ultrasound images

Tue Oct 13, 2020 18:43

Publication date: Available online 13 October 2020Source: World NeurosurgeryAuthor(s): Xiaoxiao Zheng, Xiaoqiong Li, Jinxia Xu, Yunbo Wei

Frailty and Outcomes after Craniotomy or Craniectomy for Atraumatic Chronic Subdural Hematoma

Tue Oct 13, 2020 18:43

Publication date: Available online 13 October 2020Source: World NeurosurgeryAuthor(s): Rahul A. Sastry, Nathan Pertsch, Oliver Tang, Belinda Shao, Steven A. Toms, Robert J. Weil

A Novel Parameter to Predict Supraclinoid Aneurysm Persistence After Flow Diversion with the Pipeline Embolization Device

Tue Oct 13, 2020 18:43

Publication date: Available online 13 October 2020Source: World NeurosurgeryAuthor(s): Sandeep Muram, Muneer Eesa, Brooke L. Belanger, Mohammed Almekhlafi, Mayank Goyal, William Morrish, John H. Wong, Santiago Gomez-Paz, Yosuke Akamatsu, Mohamed M. Salem, Timothy M. Robinson, Justin M. Moore, Ajith J. Thomas, Christopher S. Ogilvy, Alim P. Mitha

Workplace Violence and Neurosurgery: Insights from a Nationwide Survey

Tue Oct 13, 2020 18:43

Publication date: Available online 13 October 2020Source: World NeurosurgeryAuthor(s): Tyler Schmidt, Stephen Susa, Thomas Pieters, Samuel Tomlinson, Joshua M. Rosenow, Kristopher Kimmell, Jeremy T. Phelps, In affiliation with the Council of State Neurosurgical Societies (CSNS)

Typical and atypical radiographic features of symptomatic osteoblastoma in the spine

Tue Oct 13, 2020 18:43

Publication date: Available online 13 October 2020Source: World NeurosurgeryAuthor(s): Keyuan Chen, Chunyan Tian, Shaomin Yang, Songbo Han, Liang Jiang, Feng Wei, Huishu Yuan, Xiaoguang Liu, Zhongjun Liu

Application of Ultrasonic Doppler Technology Based on Wavelet Threshold Denoising Algorithm in Fetal Heart Rate and Central Nervous System Malformation Detection

Tue Oct 13, 2020 18:43

Publication date: Available online 13 October 2020Source: World NeurosurgeryAuthor(s): Zhiheng Yan, Xiaoyan Xu, Yixuan Wang, Tiangang Li, Bin Ma, Lei Yang, Yan Lu, Quanlin Li

An Evaluation of Neurosurgical Practices During the COVID-19 Pandemic

Tue Oct 13, 2020 18:43

Publication date: Available online 13 October 2020Source: World NeurosurgeryAuthor(s): Panayiotis E. Pelargos, Arpan R. Chakraborty, Owoicho Adogwa, Karin Swartz, Yan D. Zhao, Zachary A. Smith, Ian F. Dunn, Andrew M. Bauer

CT Image Analysis of Neuromuscular Electrical Stimulation in the Treatment of Knee Osteoarthritis with Different Radiological Characteristics Based on Iterative Reconstruction Algorithm

Tue Oct 13, 2020 18:43

Publication date: Available online 12 October 2020Source: World NeurosurgeryAuthor(s): Weijin Xing, Mubin Cai, Chuanzi Li, Zhongshi Nie, Wencai Tang

Atypical course of vertebral artery outside the cervical spine – case report and literature review

Tue Oct 13, 2020 18:43

Publication date: Available online 12 October 2020Source: World NeurosurgeryAuthor(s): Zygmunt Siedlecki, Mateusz Szostak, Karol Nowak, Maciej Śniegocki

Changing Hands: A Rising Role of the Tumor Surgeon in Teaching Sylvian Fissure Dissection

Tue Oct 13, 2020 18:43

Publication date: Available online 12 October 2020Source: World NeurosurgeryAuthor(s): Stephen G. Bowden, Dominic A. Siler, Stephanie Radu, Cody Woll, Ali I. Rae, Barry Cheaney, Joseph G. Nugent, Brittany Stedelin, Justin S. Cetas, Aclan Dogan, Seunggu J. Han

Mazor X Stealth Robotic Technology: A Technical Note

Tue Oct 13, 2020 18:43

Publication date: Available online 12 October 2020Source: World NeurosurgeryAuthor(s): Timothy E. O’Connor, Mary Margaret O’Hehir, Asham Khan, Jennifer Z. Mao, Lauren C. Levy, Jeffrey P. Mullin, John Pollina

ScienceDirect Publication: Brain Research Bulletin

Tue Oct 13, 2020 18:43

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Targeting pyroptosis to regulate ischemic stroke injury: molecular mechanisms and preclinical evidences

Publication date: Available online 14 October 2020Source: Brain Research BulletinAuthor(s): Anqi Ye, Wanting Li, Lin Zhou, Luyao Ao, Weirong Fang, Yunman Li

ScienceDirect Publication: Brain Research Bulletin

Wed Oct 14, 2020 19:39

Active avoidance learning in WAG/Rij rats with genetic predisposition to absence epilepsy

Publication date: Available online 13 October 2020Source: Brain Research BulletinAuthor(s): Evgenia Sitnikova, Kirill Smirnov

ScienceDirect Publication: Brain Research Bulletin

Wed Oct 14, 2020 19:39

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The New England Journal of Medicine: Search Results in Infectious Disease

Safety and Immunogenicity of Two RNA-Based Covid-19 Vaccine Candidates

Since the first cases of coronavirus disease 2019 (Covid-19) in Wuhan, China, in December 2019, pandemic illness has spread to millions of persons worldwide. An increased risk of severe disease and death has been noted among the elderly and among persons with preexisting medical conditions. No…

The New England Journal of Medicine: Search Results in Infectious Disease

Wed Oct 14, 2020 03:00

Supporting Clinicians during Covid-19 and Beyond — Learning from Past Failures and Envisioning New Strategies

Clinicians are facing important emotional stressors during the Covid-19 pandemic, including grief from seeing so many patients die, fears of contracting the virus and infecting their family members, and anger over health care disparities and other systems failures. For some, these stressors have…

The New England Journal of Medicine: Search Results in Infectious Disease

Wed Oct 14, 2020 03:00

Holding Up

How are you holding up? This question has become my pandemic refrain, the way I begin all my virtual visits these days. I imagine Atlas, a Titan condemned to forever hold up the heavens after losing in battle to the invincible Greek god Zeus: knees bent, back hunched, arms raised above his head as…

The New England Journal of Medicine: Search Results in Infectious Disease

Wed Oct 14, 2020 03:00

Safety and Immunogenicity of SARS-CoV-2 mRNA-1273 Vaccine in Older Adults

The coronavirus disease 2019 (Covid-19) pandemic is an international public health emergency with major social and economic disruptions and devastating health consequences. The rapid development of vaccines is imperative. More than 30 vaccine candidates against severe acute respiratory syndrome…

The New England Journal of Medicine: Search Results in Infectious Disease

Tue Sep 29, 2020 03:00

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Cortex

Commonalities in alpha and beta neural desynchronizations during prediction in language comprehension and production

Publication date: Available online 13 October 2020Source: CortexAuthor(s): Simone Gastaldon, Giorgio Arcara, Eduardo Navarrete, Francesca Peressotti

Cortex

Wed Oct 14, 2020 18:53

Multimodal Comprehension in Left Hemisphere Stroke Patients

Publication date: Available online 12 October 2020Source: CortexAuthor(s): Gabriella Vigliocco, Anna Krason, Harrison Stoll, Alessandro Monti, Laurel J. Buxbaum

Cortex

Tue Oct 13, 2020 16:03

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Latest Results for Investigational New Drugs

The novel low molecular weight MYC antagonist MYCMI-6 inhibits proliferation and induces apoptosis in breast cancer cells

Summary Background The MYC oncogene is one of the most frequently altered driver genes in cancer. MYC is thus a potential target for cancer treatment as well as a biomarker for the disease. However, as a target for treatment, MYC has traditionally been regarded as “undruggable” or difficult to target. We set out to evaluate the efficacy of a novel MYC inhibitor known as MYCMI-6, which acts by preventing MYC from interacting with its cognate partner MAX. Methods MYCMI-6 response...

Latest Results for Investigational New Drugs

Wed Oct 14, 2020 03:00

A phase Ib study of the highly selective MET-TKI savolitinib plus gefitinib in patients with EGFR -mutated, MET -amplified advanced non-small-cell lung cancer

Summary Epidermal growth factor receptor tyrosine kinase inhibitors (EGFR-TKIs) are recommended first-line treatments in EGFR-mutated (EGFRm) non-small-cell lung cancer (NSCLC). However, acquired resistance (e.g. MET amplification) is frequently observed. Savolitinib (volitinib, HMPL-504, AZD6094) is an oral, potent, and highly selective MET-TKI. In this phase Ib, open-label, multicenter study, we enrolled Chinese patients with EGFRm advanced NSCLC, whose disease progressed following...

Latest Results for Investigational New Drugs

Wed Oct 14, 2020 03:00

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Autoimmunity Reviews

Editorial Board

Publication date: November 2020Source: Autoimmunity Reviews, Volume 19, Issue 11Author(s):

Autoimmunity Reviews

Wed Oct 14, 2020 18:37

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Review: Detection and quantification of proteins in human urine

Publication date: Available online 14 October 2020Source: TalantaAuthor(s): Sultan Aitekenov, Abduzhappar Gaipov, Rostislav Bukasov

Microheterogeneity and preanalytical stability of protein biomarkers of inflammation and renal function

Wed Oct 14, 2020 18:33

Publication date: Available online 14 October 2020Source: TalantaAuthor(s): Jie Gao, Arve Ulvik, Adrian McCann, Per Magne Ueland, Klaus Meyer

Ultra sensitive bio-detection using single-electron effect

Wed Oct 14, 2020 18:33

Publication date: Available online 14 October 2020Source: TalantaAuthor(s): Shiva Ashoori, Farshid Raissi, Maryam Naderpour, Mohammad Mahdi Ghezelayagh, Reza Malekabadi Zadeh

UHPLC-MS/MS analysis of cannabidiol metabolites in serum and urine samples. Application to an individual treated with medical cannabis

Wed Oct 14, 2020 18:33

Publication date: Available online 14 October 2020Source: TalantaAuthor(s): Simona Pichini, Sara Malaca, Massimo Gottardi, Ana Pilar Pérez-Acevedo, Esther Papaseit, Clara Perez-Maña, Magí Farré, Roberta Pacifici, Adriano Tagliabracci, Giulio Mannocchi, Francesco Paolo Busardò

Dual electrophoretically-mediated microanalysis in multiple injection mode for the simultaneous determination of acetylcholinesterase and α-glucosidase activity applied to selected polyphenols

Wed Oct 14, 2020 18:33

Publication date: Available online 14 October 2020Source: TalantaAuthor(s): Diogo Alexandre Siebert, Juliana Soares Campos, Michele Debiasi Alberton, Luciano Vitali, Gustavo Amadeu Micke

Electrochemical screening of genoprotective and antioxidative effectiveness of Origanum vulgare L. and its functionality in the prevention of neurodegenerative disorders

Wed Oct 14, 2020 18:33

Publication date: 1 February 2021Source: Talanta, Volume 223, Part 2Author(s): Marta Ligaj, Joanna Kobus-Cisowska, Oskar Szczepaniak, Piotr Szulc, Dariusz Kikut-Ligaj, Anna Mikołajczak-Ratajczak, Patryk Bykowski, Daria Szymanowska, Monika Przeor, Krzysztof Polewski, Maciej Jarzębski

Construction of a red emission fluorescent protein chromophore-based probe for detection of carboxylesterase 1 and carbamate pesticide in culture cells

Tue Oct 13, 2020 17:57

Publication date: 1 February 2021Source: Talanta, Volume 223, Part 2Author(s): Jianan Dai, Yadan Hou, Jichun Wu, Guoyan Zhong, Rui Gao, Baoxing Shen, He Huang

Novel trends and applications of multidimensional chromatography in the analysis of food, cosmetics and medicine bearing essential oils

Tue Oct 13, 2020 17:57

Publication date: 1 February 2021Source: Talanta, Volume 223, Part 1Author(s): Dalia M. Rasheed, Ahmed Serag, Zeinab T. Abdel Shakour, Mohamed Farag

Integrated paper-based 3D platform for long-term cell culture and in situ cell viability monitoring of Alzheimer's disease cell model

Tue Oct 13, 2020 17:57

Publication date: 1 February 2021Source: Talanta, Volume 223, Part 2Author(s): Meng-Meng Liu, Hui Liu, Shan-Hong Li, Yu Zhong, Yao Chen, Zi-Zhen Guo, Wei Chen, Xin-Hua Lin, Yun Lei, Ai-Lin Liu

Fluorescence switch of gold nanoclusters stabilized with bovine serum albumin for efficient and sensitive detection of cysteine and copper ion in mice with Alzheimer's disease

Tue Oct 13, 2020 17:57

Publication date: Available online 13 October 2020Source: TalantaAuthor(s): Yaxin Niu, Tong Ding, Junmin Liu, Guanglu Zhang, Lili Tong, Xiufen Cheng, Yanmei Yang, Zhenzhen Chen, Bo Tang

Sequential fusion of information from two portable spectrometers for improved prediction of moisture and soluble solids content in pear fruit

Tue Oct 13, 2020 17:57

Publication date: Available online 13 October 2020Source: TalantaAuthor(s): Puneet Mishra, Federico Marini, Bastiaan Brouwer, Jean Michel Roger, Alessandra Biancolillo, Ernst Woltering, Esther Hogeveen-van Echtelt

Characterization of membrane-bound metalloproteins in the anaerobic ammonium-oxidizing bacterium “Candidatus Kuenenia stuttgartiensis” strain CSTR1

Tue Oct 13, 2020 17:57

Publication date: Available online 12 October 2020Source: TalantaAuthor(s): Rohit Budhraja, Shubhangi Karande, Chang Ding, Maria K. Ullrich, Stephan Wagner, Thorsten Reemtsma, Lorenz Adrian

A new method to extract 232Th, 230Th and 231Pa from seawater using a bulk-extraction technique with Nobias PA-1 chelating resin

Tue Oct 13, 2020 17:57

Publication date: Available online 11 October 2020Source: TalantaAuthor(s): Paulina Pinedo-González, Robert F. Anderson, Sebastian M. Vivancos, Frank J. Pavia, Martin Q. Fleisher

Preparation and application of peptide molecularly imprinted material based on mesoporous metal-organic framework

Tue Oct 13, 2020 17:57

Publication date: Available online 10 October 2020Source: TalantaAuthor(s): Min Wang, Lingyi Zhang, Yameng Zhao, Weibing Zhang

Tue Oct 13, 2020 17:57

On-line electrochemical preconcentration and electrochemical hydride generation for determination of antimony by high-resolution continuum source atomic absorption spectrometry

Publication date: Available online 10 October 2020Source: TalantaAuthor(s): Jakub Masac, Lubomir Machynak, Jan Lovic, Ernest Beinrohr, Frantisek Cacho

Rapid Vertical Flow Immunoassay on AuNP Plasmonic Paper for SERS-based Point of Need Diagnostics

Tue Oct 13, 2020 17:57

Publication date: Available online 10 October 2020Source: TalantaAuthor(s): Richard Frimpong, Wongi Jang, Jun-Hyun Kim, Jeremy D. Driskell

A NIR fluorescence probe having significant fluorescence turn-on signal at 700 nm and large Stokes shift for rapid detection of HOCl in vivo

Tue Oct 13, 2020 17:57

Publication date: Available online 10 October 2020Source: TalantaAuthor(s): Haiyan Zhang, Xinyu Yin, Jiaxin Hong, Yingzhen Deng, Guoqiang Feng

FRET-based fluorometry assay for curcumin detecting using PVP-templated Cu NCs

Tue Oct 13, 2020 17:57

Publication date: Available online 8 October 2020Source: TalantaAuthor(s): Zhixia Yao, Hanmeng Liu, Yaosheng Liu, Yongxing Diao, Guangxing Hu, Qifang Zhang, Zhuang Li

Electromembrane extraction of anthracyclines from plasma: comparison with conventional extraction techniques

Tue Oct 13, 2020 17:57

Publication date: Available online 8 October 2020Source: TalantaAuthor(s): Hana Bavlovič Piskáčková, Elisabeth Leere Øiestad, Nela Váňová, Júlia Lengvarská, Petra Štěrbová-Kovaříková, Stig Pedersen-Bjergaard

Microscale Vacuum Distillation Apparatus for High-Boiling, Air- and Heat-Sensitive Liquids

Tue Oct 13, 2020 17:57

Publication date: Available online 8 October 2020Source: TalantaAuthor(s): Sumeng Liu, Gregory S. Girolami

A new method towards the detection of DNA mutation by Surface-Enhanced Raman Spectroscopy

Tue Oct 13, 2020 17:57

Publication date: 1 February 2021Source: Talanta, Volume 223, Part 2Author(s): Jiayu Zeng, Meiyu Dong, Bixue Zhu, Dongmei Chen, Yang Li

Screening aptamers for serine β-lactamase-expressing bacteria with Precision-SELEX

Wed Oct 14, 2020 18:33

Publication date: Available online 8 October 2020Source: TalantaAuthor(s): Fang Yu, Jing Chen, Zecheng Wang, Huixin Yang, Hui Li, Wenchao Jia, Shuyuan Xue, Hexin Xie, Danke Xu

Targeted metabolomics in formalin-fixed paraffin-embedded tissue specimens: Liquid chromatography-tandem mass spectrometry determination of acidic metabolites in cancer research

Tue Oct 13, 2020 17:57

Publication date: Available online 7 October 2020Source: TalantaAuthor(s): Alex Gomez-Gomez, MohammadA. Sabbaghi, Noemí Haro, Joan Albanell, Silvia Menéndez, Mónica González, Gabriel Gil-Gómez, Ana Rovira, Oscar J. Pozo

Evaluation of Thin Film Microextraction for trace elemental analysis of liquid samples using LIBS detection

Tue Oct 13, 2020 17:57

Publication date: 1 February 2021Source: Talanta, Volume 223, Part 2Author(s): L. Ripoll, J. Navarro-González, S. Legnaioli, V. Palleschi, M. Hidalgo

Electrochemical Micropipette-Tip for Low-Cost Environmental Applications: Determination of Anionic Surfactants through their Interaction with Methylene Blue

Wed Oct 14, 2020 18:33

Publication date: Available online 5 October 2020Source: TalantaAuthor(s): Andrea González-López, Estefanía Costa-Rama, M. Teresa Fernández-Abedul

Porous thin-film molecularly imprinted polymer device for simultaneous determination of phenol, alkylphenol and chlorophenol compounds in water

Tue Oct 13, 2020 17:57

Publication date: Available online 5 October 2020Source: TalantaAuthor(s): Ghadeer F. Abu-Alsoud, Christina S. Bottaro

Preparation of glycan-oriented imprinted polymer coating Gd-doped silicon nanoparticles for targeting cancer Tn antigens and dual-modal cell imaging via boronate-affinity surface imprinting

Tue Oct 13, 2020 17:57

Publication date: Available online 30 September 2020Source: TalantaAuthor(s): Xing-Hui Ren, Hai-Yan Wang, Si Li, Xi-Wen He, Wen-You Li, Yu-Kui Zhang

Dispersive liquid-liquid microextraction (DLLME) and external real matrix calibration for the determination of the UV absorber 2-(2H-benzotriazol-2-yl)-4,6-di-tert-pentylphenol (UV 328) and its metabolites in human blood

Tue Oct 13, 2020 17:57

Publication date: Available online 28 September 2020Source: TalantaAuthor(s): Heike Denghel, Thomas Göen

Quantitation of phosphatidylethanol in dried blood after volumetric absorptive microsampling

Tue Oct 13, 2020 17:57

Publication date: Available online 24 September 2020Source: TalantaAuthor(s): Katleen Van Uytfanghe, Maria del Mar Ramirez Fernandez, Aurelie De Vos, Sarah MR. Wille, Christophe Stove

An electrochemical molecularly imprinted sensor based on chitosan capped with gold nanoparticles and its application for highly sensitive butylated hydroxyanisole analysis in foodstuff products

Tue Oct 13, 2020 17:57

Publication date: Available online 24 September 2020Source: TalantaAuthor(s): Soukaina Motia, Benachir Bouchikhi, Nezha El Bari

Machine learning tools to estimate the severity of matrix effects and predict analyte recovery in inductively coupled plasma optical emission spectrometry

Tue Oct 13, 2020 17:57

Publication date: Available online 15 September 2020Source: TalantaAuthor(s): Jake A. Carter, Logan M. O’Brien, Tina Harville, Bradley T. Jones, George L. Donati

Monitoring N-Nitrosamines impurities in ranitidine pharmaceuticals using microextraction and gas chromatography-mass spectrometry

Tue Oct 13, 2020 17:57

Publication date: Available online 15 September 2020Source: TalantaAuthor(s): Claudia Giménez-Campillo, Marta Pastor-Belda, Natalia Campillo, Manuel Hernández-Córdoba, Pilar Viñas

Ultra-small four-emission-point spectral-detection system using seven-dichroic-mirror array

Tue Oct 13, 2020 17:57

Publication date: Available online 14 September 2020Source: TalantaAuthor(s): Takashi Anazawa, Motohiro Yamazaki, Shuhei Yamamoto, Ryoji Inaba

Novel approach to the measurement of antithyroglobulin antibodies in human serum –application of the Quartz Crystal Microbalance sensors

Tue Oct 13, 2020 17:57

Publication date: Available online 28 August 2020Source: TalantaAuthor(s): Lidija S. Vrhovac, Sonja A. Šelemetjev, Saša Vatić, Aleksandar Mitrović, Jelica R. Milošević, Aleksandar.Đ. Lolić, Anđelo D. Beletić, Natalija Đ. Polović

Tue Oct 13, 2020 17:57

Portable Gas Chromatograph Calibration with Gases of Varying Viscosities

Publication date: Available online 25 April 2020Source: TalantaAuthor(s): Vera Tschedanoff, Serge M.A. Biollaz, Alexander Wokaun, Tilman J. Schildhauer